Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [50-359]' and Ligand = 'BDBM50433916'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [50-359] (Homo sapiens (Human))	BDBM50433916 (PS653 ('1,6-dihydrodibenzo[c,d,g]indazol-6-one...) Show SMILES O=C1c2ccccc2-c2[nH]nc3cccc1c23 Show InChI InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	7.4	n/a
Universitätsklinikum Frankfurt					Assay Description Titrations were performed by a 0.4 µl injection followed by 19 successive injections (2 µl) of each compound(adenosine 500 µM, PS653 250 µM) into a 2...				Cell Chem Biol 23: 1193-1205 (2016) Article DOI: 10.1016/j.chembiol.2016.06.017 BindingDB Entry DOI: 10.7270/Q23N226C
					More data for this Ligand-Target Pair