Found 250 hits Enz. Inhib. hit(s) with Target = 'Galactokinase' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Galactokinase
(Homo sapiens (Human)) | BDBM50588170
(CHEMBL5088290)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)c(N)c3o2)N1)c1ccc(C)cc1Cl)C(=O)NCc1cnn(C)c1 |t:1,4| | PDB
UniProtKB/SwissProt
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588172
(CHEMBL5073602)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4ccc(F)c(N)c4o3)=NC2c2ccc(C)cc2Cl)cn1 |c:9,27| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588172
(CHEMBL5073602)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4ccc(F)c(N)c4o3)=NC2c2ccc(C)cc2Cl)cn1 |c:9,27| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588170
(CHEMBL5088290)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)c(N)c3o2)N1)c1ccc(C)cc1Cl)C(=O)NCc1cnn(C)c1 |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588173
(CHEMBL5087686)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4ccc(F)c(N)c4o3)=N[C@H]2c2ccc(C)cc2Cl)cn1 |r,c:9,27| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588173
(CHEMBL5087686)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4ccc(F)c(N)c4o3)=N[C@H]2c2ccc(C)cc2Cl)cn1 |r,c:9,27| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588167
(CHEMBL5089409)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-c1cnc(C)nc1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588167
(CHEMBL5089409)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-c1cnc(C)nc1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588163
(CHEMBL5072646)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-n1ccnc1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588168
(CHEMBL5075869)Show SMILES CC1=C([C@@H](N=C(Nc2nc3cccc(N)c3o2)N1)c1ccc(C)cc1Cl)C(=O)NCc1cnn(C)c1 |r,t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588163
(CHEMBL5072646)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-n1ccnc1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588168
(CHEMBL5075869)Show SMILES CC1=C([C@@H](N=C(Nc2nc3cccc(N)c3o2)N1)c1ccc(C)cc1Cl)C(=O)NCc1cnn(C)c1 |r,t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588171
(CHEMBL5077147)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4cccc(N)c4o3)=NC2c2ccc(C)cc2Cl)cn1 |c:9,26| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588171
(CHEMBL5077147)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4cccc(N)c4o3)=NC2c2ccc(C)cc2Cl)cn1 |c:9,26| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588154
(CHEMBL5087173)Show SMILES CC1=C(C(N=C(Nc2nc3cccc(N)c3o2)N1)c1ccc(C)cc1Cl)C(=O)NCc1cnn(C)c1 |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588153
(CHEMBL5094206)Show SMILES CC1=C(C(N=C(Nc2nc3cccc(N)c3o2)N1)c1ccccc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588154
(CHEMBL5087173)Show SMILES CC1=C(C(N=C(Nc2nc3cccc(N)c3o2)N1)c1ccc(C)cc1Cl)C(=O)NCc1cnn(C)c1 |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588153
(CHEMBL5094206)Show SMILES CC1=C(C(N=C(Nc2nc3cccc(N)c3o2)N1)c1ccccc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 234 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588166
(CHEMBL5081118)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-c1ccc(C)nc1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588166
(CHEMBL5081118)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-c1ccc(C)nc1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 347 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588158
(CHEMBL5090335)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(C)cc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 389 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588158
(CHEMBL5090335)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(C)cc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588159
(CHEMBL5088230)Show SMILES COc1ccc(C2N=C(Nc3nc4ccc(F)cc4o3)NC(C)=C2C(=O)Nc2cc(ccn2)C(O)=O)c(Cl)c1 |c:24,t:7| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588162
(CHEMBL5085360)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)N1CCOCC1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588159
(CHEMBL5088230)Show SMILES COc1ccc(C2N=C(Nc3nc4ccc(F)cc4o3)NC(C)=C2C(=O)Nc2cc(ccn2)C(O)=O)c(Cl)c1 |c:24,t:7| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 447 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588162
(CHEMBL5085360)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)N1CCOCC1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 447 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588155
(CHEMBL5091860)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccccc1Br)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588155
(CHEMBL5091860)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccccc1Br)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 562 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM249789
(US9447087, 17 | US9447087, 57)Show SMILES Clc1ccccc1C1N=C(Nc2nc3ccccc3o2)NC2=C1C(=O)CCC2 |c:24,t:9| Show InChI InChI=1S/C21H17ClN4O2/c22-13-7-2-1-6-12(13)19-18-15(9-5-10-16(18)27)23-20(25-19)26-21-24-14-8-3-4-11-17(14)28-21/h1-4,6-8,11,19H,5,9-10H2,(H2,23,24,25,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 595 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF UTAH RESEARCH FOUNDATION
US Patent
| Assay Description Assay details and protocol: The primary assay monitored ATP depletion using Promega's KinaseGlo technology, where ATP levels are measured through... |
US Patent US9447087 (2016)
BindingDB Entry DOI: 10.7270/Q25Q4V08 |
More data for this Ligand-Target Pair | |
Galactokinase
(Mus musculus) | BDBM50588172
(CHEMBL5073602)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4ccc(F)c(N)c4o3)=NC2c2ccc(C)cc2Cl)cn1 |c:9,27| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588138
(CHEMBL5079293)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccccc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Galactokinase
(Homo sapiens (Human)) | BDBM249831
(US9447087, 67)Show SMILES Brc1cccnc1C1N=C(Nc2nc3ccccc3o2)NC2=C1C(=O)CCC2 |c:24,t:9| Show InChI InChI=1S/C20H16BrN5O2/c21-11-5-4-10-22-17(11)18-16-13(7-3-8-14(16)27)23-19(25-18)26-20-24-12-6-1-2-9-15(12)28-20/h1-2,4-6,9-10,18H,3,7-8H2,(H2,23,24,25,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 651 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF UTAH RESEARCH FOUNDATION
US Patent
| Assay Description Assay details and protocol: The primary assay monitored ATP depletion using Promega's KinaseGlo technology, where ATP levels are measured through... |
US Patent US9447087 (2016)
BindingDB Entry DOI: 10.7270/Q25Q4V08 |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588138
(CHEMBL5079293)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccccc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Galactokinase
(Mus musculus) | BDBM50588170
(CHEMBL5088290)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)c(N)c3o2)N1)c1ccc(C)cc1Cl)C(=O)NCc1cnn(C)c1 |t:1,4| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50380337
(CHEMBL2017798)Show SMILES Oc1ccc(O)c(c1)C1NC(=O)C(C#N)=C(SCc2ccccc2)S1 |t:15| Show InChI InChI=1S/C18H14N2O3S2/c19-9-14-16(23)20-17(13-8-12(21)6-7-15(13)22)25-18(14)24-10-11-4-2-1-3-5-11/h1-8,17,21-22H,10H2,(H,20,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human galactokinase after 30 mins by Kinase-GloTM assay |
ACS Med Chem Lett 2: 667-672 (2011)
Article DOI: 10.1021/ml200131j BindingDB Entry DOI: 10.7270/Q251406Q |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM249808
(US9447087, 41)Show SMILES Brc1ccccc1C1N=C(Nc2nc3ccccc3o2)NC2=C1C(=O)CCC2 |c:24,t:9| Show InChI InChI=1S/C21H17BrN4O2/c22-13-7-2-1-6-12(13)19-18-15(9-5-10-16(18)27)23-20(25-19)26-21-24-14-8-3-4-11-17(14)28-21/h1-4,6-8,11,19H,5,9-10H2,(H2,23,24,25,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 749 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF UTAH RESEARCH FOUNDATION
US Patent
| Assay Description Assay details and protocol: The primary assay monitored ATP depletion using Promega's KinaseGlo technology, where ATP levels are measured through... |
US Patent US9447087 (2016)
BindingDB Entry DOI: 10.7270/Q25Q4V08 |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588161
(CHEMBL5084901)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-n1cccn1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588161
(CHEMBL5084901)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)-n1cccn1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 776 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588156
(CHEMBL5081119)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(F)cc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588156
(CHEMBL5081119)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(F)cc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 891 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50380339
(CHEMBL2017800)Show SMILES Oc1ccc(O)c(c1)C1NC(=O)C(C#N)=C(SCc2cccc(c2)N2CCOCC2)S1 |t:15| Show InChI InChI=1S/C22H21N3O4S2/c23-12-18-20(28)24-21(17-11-16(26)4-5-19(17)27)31-22(18)30-13-14-2-1-3-15(10-14)25-6-8-29-9-7-25/h1-5,10-11,21,26-27H,6-9,13H2,(H,24,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human galactokinase after 30 mins by Kinase-GloTM assay |
ACS Med Chem Lett 2: 667-672 (2011)
Article DOI: 10.1021/ml200131j BindingDB Entry DOI: 10.7270/Q251406Q |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588147
(CHEMBL5094727)Show SMILES CC1=C(C(N=C(Nc2nc3cccc(C)c3o2)N1)c1ccccc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 933 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Mus musculus) | BDBM50588173
(CHEMBL5087686)Show SMILES CCn1cc(CNC(=O)C2=C(C)NC(Nc3nc4ccc(F)c(N)c4o3)=N[C@H]2c2ccc(C)cc2Cl)cn1 |r,c:9,27| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588147
(CHEMBL5094727)Show SMILES CC1=C(C(N=C(Nc2nc3cccc(C)c3o2)N1)c1ccccc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588132
(CHEMBL5092131)Show SMILES CC1=C(C(N=C(Nc2nc3ccccc3o2)N1)c1ccccc1Cl)C(=O)NCc1cn(C)cn1 |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588157
(CHEMBL5082520)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(Cl)cc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM249793
(US9447087, 22)Show SMILES O=C1CCCC2=C1C1(CCSCC1)N=C(Nc1nc3ccccc3o1)N2 |c:5,t:15| Show InChI InChI=1S/C19H20N4O2S/c24-14-6-3-5-13-16(14)19(8-10-26-11-9-19)23-17(20-13)22-18-21-12-4-1-2-7-15(12)25-18/h1-2,4,7H,3,5-6,8-11H2,(H2,20,21,22,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF UTAH RESEARCH FOUNDATION
US Patent
| Assay Description Assay details and protocol: The primary assay monitored ATP depletion using Promega's KinaseGlo technology, where ATP levels are measured through... |
US Patent US9447087 (2016)
BindingDB Entry DOI: 10.7270/Q25Q4V08 |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588135
(CHEMBL5076119)Show SMILES CC1=C(C(N=C(Nc2nc3ccccc3o2)N1)c1ccccc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588157
(CHEMBL5082520)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(Cl)cc1Cl)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |
Galactokinase
(Homo sapiens (Human)) | BDBM50588165
(CHEMBL5073924)Show SMILES CC1=C(C(N=C(Nc2nc3ccc(F)cc3o2)N1)c1ccc(cc1Cl)N1CCCC1)C(=O)Nc1cc(ccn1)C(O)=O |t:1,4| | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00945 BindingDB Entry DOI: 10.7270/Q2Z323MD |
More data for this Ligand-Target Pair | |