Compile Data Set for Download or QSAR

Found 1844 hits Enz. Inhib. hit(s) with Target = 'Stromal cell-derived factor 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50335557 (CHEMBL1652605 | N,N-dipropyl-N'-[4-({[(1H-imidazol...) Show SMILES CCCN(CCC)CCCCN(C)Cc1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1 Show InChI InChI=1S/C28H45N7/c1-5-16-34(17-6-2)19-8-7-18-32(3)21-25-9-11-26(12-10-25)22-35(23-27-29-13-14-30-27)24-28-31-15-20-33(28)4/h9-15,20H,5-8,16-19,21-24H2,1-4H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem		0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50270276 (CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...) Show SMILES C(NCc1ccccn1)c1ccc(CN2CCCNCCNCCCNCC2)cc1 Show InChI InChI=1S/C24H38N6/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...				J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q
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C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50270276 (CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...) Show SMILES C(NCc1ccccn1)c1ccc(CN2CCCNCCNCCCNCC2)cc1 Show InChI InChI=1S/C24H38N6/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50315305 ((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-N-(4-amin...) Show SMILES NCCCCN(Cc1nc2ccccc2[nH]1)[C@H]1CCCc2cccnc12 |r| Show InChI InChI=1S/C21H27N5/c22-12-3-4-14-26(15-20-24-17-9-1-2-10-18(17)25-20)19-11-5-7-16-8-6-13-23-21(16)19/h1-2,6,8-10,13,19H,3-5,7,11-12,14-15,22H2,(H,24,25)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369245 (CHEMBL4170392) Show SMILES COc1cc(\C=C\C(=O)c2ccc(cc2)C(C)C)ccc1O Show InChI InChI=1S/C19H20O3/c1-13(2)15-6-8-16(9-7-15)17(20)10-4-14-5-11-18(21)19(12-14)22-3/h4-13,21H,1-3H3/b10-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
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Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369246 (CHEMBL4160309) Show SMILES COc1cc(\C=C\C(=O)c2ccc(Br)cc2)ccc1O Show InChI InChI=1S/C16H13BrO3/c1-20-16-10-11(3-9-15(16)19)2-8-14(18)12-4-6-13(17)7-5-12/h2-10,19H,1H3/b8-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369285 (CHEMBL4160346) Show SMILES COc1cc(\C=C\C(=O)c2ccc(Cl)cc2Cl)ccc1O Show InChI InChI=1S/C16H12Cl2O3/c1-21-16-8-10(3-7-15(16)20)2-6-14(19)12-5-4-11(17)9-13(12)18/h2-9,20H,1H3/b6-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50042947 (1-(4-Chloro-phenyl)-3-(4-hydroxy-3-methoxy-phenyl)...) Show SMILES COc1cc(\C=C\C(=O)c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C16H13ClO3/c1-20-16-10-11(3-9-15(16)19)2-8-14(18)12-4-6-13(17)7-5-12/h2-10,19H,1H3/b8-2+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EGFP-tagged human CXCR4 expressed in HEK293 cells assessed as inhibition of CXCL12-TR binding incubated for 5 mins prior to CXCL12-TR a...				ACS Med Chem Lett 3: 10-14 (2012) Article DOI: 10.1021/ml200017d BindingDB Entry DOI: 10.7270/Q27H1KR7
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Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369286 (CHEMBL4167574) Show SMILES COc1cc(\C=C\C(=O)c2cc(Cl)ccc2Cl)ccc1O Show InChI InChI=1S/C16H12Cl2O3/c1-21-16-8-10(3-7-15(16)20)2-6-14(19)12-9-11(17)4-5-13(12)18/h2-9,20H,1H3/b6-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50042947 (1-(4-Chloro-phenyl)-3-(4-hydroxy-3-methoxy-phenyl)...) Show SMILES COc1cc(\C=C\C(=O)c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C16H13ClO3/c1-20-16-10-11(3-9-15(16)19)2-8-14(18)12-4-6-13(17)7-5-12/h2-10,19H,1H3/b8-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369256 (CHEMBL4175451) Show SMILES COc1cc(\C=C\C(=O)c2c(Cl)cccc2Cl)ccc1O Show InChI InChI=1S/C16H12Cl2O3/c1-21-15-9-10(5-7-13(15)19)6-8-14(20)16-11(17)3-2-4-12(16)18/h2-9,19H,1H3/b8-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50615204 (CHEMBL278054) Show SMILES C(N1CCCNCCNCCCNCC1)c1cccc(CN2CCCNCCNCCCNCC2)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem		83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369321 (CHEMBL4168220) Show SMILES COc1cc(\C=C\C(=O)c2ccc(I)cc2)ccc1O Show InChI InChI=1S/C16H13IO3/c1-20-16-10-11(3-9-15(16)19)2-8-14(18)12-4-6-13(17)7-5-12/h2-10,19H,1H3/b8-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369248 (CHEMBL4163005) Show SMILES COc1cc(\C=C2/Cc3cc(Cl)ccc3C2=O)ccc1O Show InChI InChI=1S/C17H13ClO3/c1-21-16-7-10(2-5-15(16)19)6-12-8-11-9-13(18)3-4-14(11)17(12)20/h2-7,9,19H,8H2,1H3/b12-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369250 (CHEMBL4168923) Show SMILES COc1cc(\C=C\C(=O)c2ccc(Cl)cc2F)ccc1O Show InChI InChI=1S/C16H12ClFO3/c1-21-16-8-10(3-7-15(16)20)2-6-14(19)12-5-4-11(17)9-13(12)18/h2-9,20H,1H3/b6-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369280 (CHEMBL4166275) Show SMILES COc1cc(\C=C\C(=O)c2ccccc2Cl)ccc1O Show InChI InChI=1S/C16H13ClO3/c1-20-16-10-11(7-9-15(16)19)6-8-14(18)12-4-2-3-5-13(12)17/h2-10,19H,1H3/b8-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369244 (CHEMBL4169628) Show SMILES COc1cc(ccc1O)C1CC(=NN1)c1ccc(Cl)cc1 |c:12| Show InChI InChI=1S/C16H15ClN2O2/c1-21-16-8-11(4-7-15(16)20)14-9-13(18-19-14)10-2-5-12(17)6-3-10/h2-8,14,19-20H,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50270276 (CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...) Show SMILES C(NCc1ccccn1)c1ccc(CN2CCCNCCNCCCNCC2)cc1 Show InChI InChI=1S/C24H38N6/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cells				J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50035719 (1-(4-Methyl-benzyl)-1,4,8,11tetraaza-cyclotetradec...) Show SMILES Cc1ccc(CN2CCCNCCNCCCNCC2)cc1 Show InChI InChI=1S/C18H32N4/c1-17-4-6-18(7-5-17)16-22-14-3-10-20-12-11-19-8-2-9-21-13-15-22/h4-7,19-21H,2-3,8-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars		170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50615201 (1,3-Di(1,4,8,11-Tetraazacyclotetradecanyl)Propane ...) Show SMILES C(CN1CCCNCCNCCCNCC1)CN1CCCNCCNCCCNCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem		180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369330 (CHEMBL4160583) Show SMILES COc1cc(\C=C2/Oc3cc(Cl)ccc3C2=O)ccc1O Show InChI InChI=1S/C16H11ClO4/c1-20-14-6-9(2-5-12(14)18)7-15-16(19)11-4-3-10(17)8-13(11)21-15/h2-8,18H,1H3/b15-7-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50035696 (1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...) Show SMILES C(N1CCCNCCNCCCNCC1)c1ccc(CN2CCCNCCNCCCNCC2)cc1 Show InChI InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...				J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369279 (CHEMBL4166454) Show SMILES COc1cc(ccc1O)-c1cc(nc(=O)[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H13ClN2O3/c1-23-16-8-11(4-7-15(16)21)14-9-13(19-17(22)20-14)10-2-5-12(18)6-3-10/h2-9,21H,1H3,(H,19,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	267	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369249 (CHEMBL4173832) Show SMILES COc1cc(\C=C\C(=O)c2ccc(C)cc2)ccc1O Show InChI InChI=1S/C17H16O3/c1-12-3-7-14(8-4-12)15(18)9-5-13-6-10-16(19)17(11-13)20-2/h3-11,19H,1-2H3/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50042973 (1-(4-Chloro-phenyl)-3-(3,4-dihydroxy-phenyl)-prope...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(Cl)cc2)cc1O Show InChI InChI=1S/C15H11ClO3/c16-12-5-3-11(4-6-12)13(17)7-1-10-2-8-14(18)15(19)9-10/h1-9,18-19H/b7-1+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369278 (CHEMBL4162605) Show SMILES COc1cc(\C=C2/COc3cc(Cl)ccc3C2=O)ccc1O Show InChI InChI=1S/C17H13ClO4/c1-21-16-7-10(2-5-14(16)19)6-11-9-22-15-8-12(18)3-4-13(15)17(11)20/h2-8,19H,9H2,1H3/b11-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	357	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369322 (CHEMBL4170951) Show SMILES COc1cc(\C=C\C(=O)c2cccc(Cl)c2Cl)ccc1O Show InChI InChI=1S/C16H12Cl2O3/c1-21-15-9-10(6-8-14(15)20)5-7-13(19)11-3-2-4-12(17)16(11)18/h2-9,20H,1H3/b7-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	357	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369292 (CHEMBL4175213) Show SMILES Cl.NCCOc1cc(\C=C\C(=O)c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C17H16ClNO3/c18-14-5-3-13(4-6-14)15(20)7-1-12-2-8-16(21)17(11-12)22-10-9-19/h1-8,11,21H,9-10,19H2/b7-1+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	357	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369282 (CHEMBL4169688) Show SMILES COc1cc(\C=C\C(=O)c2ccc(F)cc2)ccc1O Show InChI InChI=1S/C16H13FO3/c1-20-16-10-11(3-9-15(16)19)2-8-14(18)12-4-6-13(17)7-5-12/h2-10,19H,1H3/b8-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369294 (CHEMBL4159394) Show SMILES Cl.NCCOCCOCCOc1cc(\C=C\C(=O)c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C21H24ClNO5/c22-18-5-3-17(4-6-18)19(24)7-1-16-2-8-20(25)21(15-16)28-14-13-27-12-11-26-10-9-23/h1-8,15,25H,9-14,23H2/b7-1+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	475	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369320 (CHEMBL4175047) Show SMILES Cl.NCCOCCOc1cc(\C=C2/Cc3cc(Cl)ccc3C2=O)ccc1O Show InChI InChI=1S/C20H20ClNO4/c21-16-2-3-17-14(12-16)11-15(20(17)24)9-13-1-4-18(23)19(10-13)26-8-7-25-6-5-22/h1-4,9-10,12,23H,5-8,11,22H2/b15-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	496	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369291 (CHEMBL226710) Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C15H11ClO2/c16-13-6-4-12(5-7-13)15(18)10-3-11-1-8-14(17)9-2-11/h1-10,17H/b10-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	625	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50615202 (CHEMBL5284797) Show SMILES C(C[C@H]1CNCCCNCCNCCCN1)CN1CCCNCCNCCCNCC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem		650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369247 (CHEMBL4164132) Show SMILES COc1cc(\C=C\C(=O)c2ccc(Cl)c(Cl)c2)ccc1O Show InChI InChI=1S/C16H12Cl2O3/c1-21-16-8-10(3-7-15(16)20)2-6-14(19)11-4-5-12(17)13(18)9-11/h2-9,20H,1H3/b6-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	714	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50615203 (CHEMBL277955) Show SMILES C(N1CCCNCCNCCCNCC1)c1ccnc(CN2CCCNCCNCCCNCC2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem		850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50035696 (1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...) Show SMILES C(N1CCCNCCNCCCNCC1)c1ccc(CN2CCCNCCNCCCNCC2)cc1 Show InChI InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cells				J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369283 (CHEMBL243400) Show SMILES COc1cc(\C=C\C(=O)c2ccc(cc2)C(F)(F)F)ccc1O Show InChI InChI=1S/C17H13F3O3/c1-23-16-10-11(3-9-15(16)22)2-8-14(21)12-4-6-13(7-5-12)17(18,19)20/h2-10,22H,1H3/b8-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369341 (CHEMBL4167307) Show SMILES Cl.NCCOCCOc1cc(\C=C\C(=O)c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C19H20ClNO4/c20-16-5-3-15(4-6-16)17(22)7-1-14-2-8-18(23)19(13-14)25-12-11-24-10-9-21/h1-8,13,23H,9-12,21H2/b7-1+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369289 (CHEMBL4159676) Show SMILES Clc1ccc(cc1)C(=O)\C=C\c1ccc2OCCOc2c1 Show InChI InChI=1S/C17H13ClO3/c18-14-5-3-13(4-6-14)15(19)7-1-12-2-8-16-17(11-12)21-10-9-20-16/h1-8,11H,9-10H2/b7-1+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369329 (CHEMBL4163644) Show SMILES COc1cc(ccc1O)-c1cc(nc(C)n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H15ClN2O2/c1-11-20-15(12-3-6-14(19)7-4-12)10-16(21-11)13-5-8-17(22)18(9-13)23-2/h3-10,22H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50270277 (Benzyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmeth...) Show SMILES C(NCc1ccc(CN2CCCNCCNCCCNCC2)cc1)c1ccccc1 Show InChI InChI=1S/C25H39N5/c1-2-6-23(7-3-1)20-29-21-24-8-10-25(11-9-24)22-30-18-5-14-27-16-15-26-12-4-13-28-17-19-30/h1-3,6-11,26-29H,4-5,12-22H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat...				J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50270277 (Benzyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmeth...) Show SMILES C(NCc1ccc(CN2CCCNCCNCCCNCC2)cc1)c1ccccc1 Show InChI InChI=1S/C25H39N5/c1-2-6-23(7-3-1)20-29-21-24-8-10-25(11-9-24)22-30-18-5-14-27-16-15-26-12-4-13-28-17-19-30/h1-3,6-11,26-29H,4-5,12-22H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50042992 (3-(4-Hydroxy-3-methoxy-phenyl)-1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(OC)c1 Show InChI InChI=1S/C17H16O4/c1-20-14-7-5-13(6-8-14)15(18)9-3-12-4-10-16(19)17(11-12)21-2/h3-11,19H,1-2H3/b9-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50615200 (1,6-Di(1,4,8,11-Tetraazacyclotetradecanyl)Hexane |...) Show SMILES C(CCCN1CCCNCCNCCCNCC1)CCN1CCCNCCNCCCNCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	UniChem		2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369313 (CHEMBL4174118) Show SMILES COc1cc(\C=C(/C)C(=O)c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C17H15ClO3/c1-11(17(20)13-4-6-14(18)7-5-13)9-12-3-8-15(19)16(10-12)21-2/h3-10,19H,1-2H3/b11-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369284 (CHEMBL4177186) Show SMILES COc1cc(\C=C\C(=O)c2ccc(cc2)C(O)=O)ccc1O Show InChI InChI=1S/C17H14O5/c1-22-16-10-11(3-9-15(16)19)2-8-14(18)12-4-6-13(7-5-12)17(20)21/h2-10,19H,1H3,(H,20,21)/b8-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50264279 (CHEMBL4072602) Show SMILES [H][C@@]12CC[C@@]([H])(O1)[C@H](C2)C(=O)N1CCC(CN2CCCN(CC2)c2c(CC)ccn3ccnc23)CC1 |r| Show InChI InChI=1S/C27H39N5O2/c1-2-21-8-14-31-15-9-28-26(31)25(21)30-11-3-10-29(16-17-30)19-20-6-12-32(13-7-20)27(33)23-18-22-4-5-24(23)34-22/h8-9,14-15,20,22-24H,2-7,10-13,16-19H2,1H3/t22-,23-,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]CXCL12 from CXCR4 in human Jurkat cells after 2 hrs by scintillation counting method				J Med Chem 61: 3685-3696 (2018) Article DOI: 10.1021/acs.jmedchem.8b00190 BindingDB Entry DOI: 10.7270/Q2KD21C4
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50458286 (CHEMBL2367715) Show SMILES C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)c1ccc(CNCc2ccccn2)cc1)c1cccc2ccccc12 |r| Show InChI InChI=1S/C32H37N7O2/c1-22(27-12-6-9-24-8-2-3-11-28(24)27)38-31(41)29(13-7-19-37-32(33)34)39-30(40)25-16-14-23(15-17-25)20-35-21-26-10-4-5-18-36-26/h2-6,8-12,14-18,22,29,35H,7,13,19-21H2,1H3,(H,38,41)(H,39,40)(H4,33,34,37)/t22-,29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369276 (CHEMBL4177375) Show SMILES COc1cc(\C=C\C(=N\O)\c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C16H14ClNO3/c1-21-16-10-11(3-9-15(16)19)2-8-14(18-20)12-4-6-13(17)7-5-12/h2-10,19-20H,1H3/b8-2+,18-14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair
Stromal cell-derived factor 1 (Homo sapiens (Human))	BDBM50369277 (CHEMBL4164112) Show SMILES CNc1nc(cc(n1)-c1ccc(O)c(OC)c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H16ClN3O2/c1-20-18-21-14(11-3-6-13(19)7-4-11)10-15(22-18)12-5-8-16(23)17(9-12)24-2/h3-10,23H,1-2H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 express...				J Med Chem 61: 7671-7686 (2018) Article DOI: 10.1021/acs.jmedchem.8b00657 BindingDB Entry DOI: 10.7270/Q2QF8WDS
					More data for this Ligand-Target Pair

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