Compile Data Set for Download or QSAR

Found 117 hits Enz. Inhib. hit(s) with Target = 'Tau-tubulin kinase 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602886 (CHEMBL5182036) Show SMILES CC[C@@](C)(O)C#Cc1cc2n(ccc2cn1)-c1cc(OC)nc(N)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609151 (CHEMBL5283456) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609143 (CHEMBL5268795) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609159 (CHEMBL5280210) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609138 (CHEMBL5272364) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609144 (CHEMBL5279863) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609137 (CHEMBL5282072) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609160 (CHEMBL5268080) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609145 (CHEMBL5271137) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609146 (CHEMBL5273263) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PDB UniChem	PDB	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609158 (CHEMBL5282902) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609142 (CHEMBL5290581) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609157 (CHEMBL5274162) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609139 (CHEMBL5280803) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609151 (CHEMBL5283456) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609141 (CHEMBL5288487) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609136 (CHEMBL5278744) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609140 (CHEMBL5274528) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609143 (CHEMBL5268795) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609137 (CHEMBL5282072) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602885 (CHEMBL5193906) Show SMILES CC1(N)CCN(Cc2ccn3ncnc(Nc4cc(O)cc(Br)c4)c23)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50506660 (CHEMBL4528881) Show SMILES CC1(N)CCC(CC1)Nc1ccn2ncnc(Nc3cc(O)cc(Br)c3)c12 Show InChI InChI=1S/C19H23BrN6O/c1-19(21)5-2-13(3-6-19)24-16-4-7-26-17(16)18(22-11-23-26)25-14-8-12(20)9-15(27)10-14/h4,7-11,13,24,27H,2-3,5-6,21H2,1H3,(H,22,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas-CSIC Curated by ChEMBL					Assay Description Inhibition of TTBK1 (unknown origin)				Eur J Med Chem 161: 39-47 (2019) Article DOI: 10.1016/j.ejmech.2018.10.030 BindingDB Entry DOI: 10.7270/Q2V98CC0
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609156 (CHEMBL5290252) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609144 (CHEMBL5279863) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609138 (CHEMBL5272364) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609161 (CHEMBL5279159) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50429615 (CHEMBL2334586) Show SMILES CC(C)(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI InChI=1S/C20H20N4O/c1-20(2,25)9-8-12-6-7-15-14(10-12)17-16(23-15)5-3-4-13-11-22-19(21)24-18(13)17/h6-7,10-11,23,25H,3-5H2,1-2H3,(H2,21,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609158 (CHEMBL5282902) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609160 (CHEMBL5268080) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602904 (CHEMBL5204869) Show SMILES Clc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609146 (CHEMBL5273263) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PDB UniChem	PDB	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609159 (CHEMBL5280210) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602917 (CHEMBL5200069) Show SMILES Clc1ccccc1Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602907 (CHEMBL5193488) Show SMILES COc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609162 (CHEMBL5275588) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	352	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609156 (CHEMBL5290252) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	352	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602930 (CHEMBL5181249) Show SMILES Clc1ccccc1Cn1cc(COc2ccc(Nc3ncnc4[nH]ccc34)cc2)nn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602922 (CHEMBL5184336) Show SMILES Nc1nc(Nc2ccc(Oc3cccc(Cl)c3)cc2)c2cc[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609162 (CHEMBL5275588) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602921 (CHEMBL5180098) Show SMILES Nc1nc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)c2cc[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602903 (CHEMBL5198544) Show SMILES N(c1ccc(Oc2ccccc2)cc1)c1ncnc2[nH]ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602932 (CHEMBL5178965) Show SMILES C(Cn1cc(COc2ccc(Nc3ncnc4[nH]ccc34)cc2)nn1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609152 (CHEMBL5272862) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	414	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602910 (CHEMBL5209196) Show SMILES [O-][N+](=O)c1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602906 (CHEMBL5187459) Show SMILES N#Cc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602920 (CHEMBL5187125) Show SMILES Nc1nc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)c2cc[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602931 (CHEMBL5197012) Show SMILES Clc1cccc(Cn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602911 (CHEMBL5171328) Show SMILES Nc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50602900 (CHEMBL5185704 | US11814388, Compound 3) Show SMILES COc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 1 (Homo sapiens (Human))	BDBM50609136 (CHEMBL5278744) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	571	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

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