Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily B member 1' AND taxid = 10116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily B member 1 (Rattus norvegicus)	BDBM50213094 ((1R,2R)-1-(3,4-dichlorophenethoxy)-2-(4-morpholiny...) Show SMILES Clc1ccc(CCO[C@@H]2CCCC[C@H]2N2CCOCC2)cc1Cl Show InChI InChI=1S/C18H25Cl2NO2/c19-15-6-5-14(13-16(15)20)7-10-23-18-4-2-1-3-17(18)21-8-11-22-12-9-21/h5-6,13,17-18H,1-4,7-12H2/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of rat potassium channel Kv2.1 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily B member 1 (Rattus norvegicus)	BDBM50213092 ((1R,2R)-1-(1-naphthalenethoxy)-2-(4-morpholinyl)cy...) Show SMILES C(Cc1cccc2ccccc12)O[C@@H]1CCCC[C@H]1N1CCOCC1 Show InChI InChI=1S/C22H29NO2/c1-2-9-20-18(6-1)7-5-8-19(20)12-15-25-22-11-4-3-10-21(22)23-13-16-24-17-14-23/h1-2,5-9,21-22H,3-4,10-17H2/t21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of rat potassium channel Kv2.1 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily B member 1 (Rattus norvegicus)	BDBM50213093 ((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...) Show SMILES O=C1CCN(C1)[C@@H]1CCCC[C@H]1OCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-19-12-14-23(16-19)21-10-3-4-11-22(21)25-15-13-18-8-5-7-17-6-1-2-9-20(17)18/h1-2,5-9,21-22H,3-4,10-16H2/t21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of rat potassium channel Kv2.1 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily B member 1 (Rattus norvegicus)	BDBM50213093 ((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...) Show SMILES O=C1CCN(C1)[C@@H]1CCCC[C@H]1OCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-19-12-14-23(16-19)21-10-3-4-11-22(21)25-15-13-18-8-5-7-17-6-1-2-9-20(17)18/h1-2,5-9,21-22H,3-4,10-16H2/t21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of rat potassium channel Kv2.1 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily B member 1 (Rattus norvegicus)	BDBM50213095 ((1S,2S)-1-(1-Naphthalenethoxy)-2-(3-ketopyrrolidin...) Show SMILES O=C1CCN(C1)[C@H]1CCCC[C@@H]1OCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-19-12-14-23(16-19)21-10-3-4-11-22(21)25-15-13-18-8-5-7-17-6-1-2-9-20(17)18/h1-2,5-9,21-22H,3-4,10-16H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiome Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of rat potassium channel Kv2.1 by patch-clamp method				J Med Chem 50: 2818-41 (2007) Article DOI: 10.1021/jm0604528 BindingDB Entry DOI: 10.7270/Q29Z95QZ
					More data for this Ligand-Target Pair