Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434188 (CHEMBL2385281 | US9346814, Cmpd No 2 Example 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434169 (CHEMBL2385300 | US9346814, Cmpd No 22 Example 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009366 (CHEMBL3233842 | US11504364, Compound Ref.-Comp. | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009366 (CHEMBL3233842 | US11504364, Compound Ref.-Comp. | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009364 (CHEMBL3233840) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009370 (CHEMBL3233847) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009360 (CHEMBL3233835 | US9346814, Cmpd No 23 Example 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009360 (CHEMBL3233835 | US9346814, Cmpd No 23 Example 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434163 (CHEMBL2385273 | US9346814, Cmpd No 12 Example 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434163 (CHEMBL2385273 | US9346814, Cmpd No 12 Example 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009359 (CHEMBL3233834) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM233322 (US9346814, Cmpd No 27 Example 32) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434164 (CHEMBL2385272 | US9346814, Cmpd No 13 Example 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434164 (CHEMBL2385272 | US9346814, Cmpd No 13 Example 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009331 (CHEMBL3233843 | US9346814, Cmpd No 24 Example 28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009331 (CHEMBL3233843 | US9346814, Cmpd No 24 Example 28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434165 (CHEMBL2385271 | US9346814, Cmpd No 11 Example 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434165 (CHEMBL2385271 | US9346814, Cmpd No 11 Example 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.20 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434170 (CHEMBL2385299 | US9346814, Cmpd No 21 Example 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.90 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434170 (CHEMBL2385299 | US9346814, Cmpd No 21 Example 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434166 (CHEMBL2385270 | US9346814, Cmpd No 6 Example 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434188 (CHEMBL2385281 | US9346814, Cmpd No 2 Example 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434188 (CHEMBL2385281 | US9346814, Cmpd No 2 Example 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434166 (CHEMBL2385270 | US9346814, Cmpd No 6 Example 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434188 (CHEMBL2385281 | US9346814, Cmpd No 2 Example 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10.3 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434169 (CHEMBL2385300 | US9346814, Cmpd No 22 Example 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434169 (CHEMBL2385300 | US9346814, Cmpd No 22 Example 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434169 (CHEMBL2385300 | US9346814, Cmpd No 22 Example 26) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434167 (CHEMBL2385302 | US9346814, Cmpd No 8 Example 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434167 (CHEMBL2385302 | US9346814, Cmpd No 8 Example 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434168 (CHEMBL2385301 | US9346814, Cmpd No 7 Example 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434168 (CHEMBL2385301 | US9346814, Cmpd No 7 Example 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50326392 ((2S)-1-({(2S,4S)-4-[2-(1,3-Dihydro-2H-isoindol-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50431242 (CHEMBL2333026) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009358 (CHEMBL3233833 | US9346814, Cmpd No 33 Example 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009358 (CHEMBL3233833 | US9346814, Cmpd No 33 Example 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM233323 (US9346814, Cmpd No 29 Example 34) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009352 (CHEMBL3233572) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009361 (CHEMBL3233837 | US9346814, Cmpd No 25 Example 30) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 59 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009361 (CHEMBL3233837 | US9346814, Cmpd No 25 Example 30) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009334 (CHEMBL3233554 | US9346814, Cmpd No 4 Example 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009334 (CHEMBL3233554 | US9346814, Cmpd No 4 Example 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 63 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009332 (CHEMBL3233836 | US9346814, Cmpd No 26 Example 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 64 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009362 (CHEMBL3233838 | US9346814, Cmpd No 25 Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50050513 ((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mi... | Bioorg Med Chem Lett 22: 3412-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.107 BindingDB Entry DOI: 10.7270/Q27D2W5P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50050513 ((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009332 (CHEMBL3233836 | US9346814, Cmpd No 26 Example 31) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp Curated by ChEMBL | Assay Description Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometry | J Med Chem 57: 3053-74 (2014) Article DOI: 10.1021/jm500031w BindingDB Entry DOI: 10.7270/Q2P84DFW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50009362 (CHEMBL3233838 | US9346814, Cmpd No 25 Example 29) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 8.3 | 37 |
Universiteit Antwerp; Fox Chase Cancer Center US Patent | Assay Description Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ... | US Patent US9346814 (2016) BindingDB Entry DOI: 10.7270/Q2W37V6D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50050513 ((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl endopeptidase FAP (Mus musculus (Mouse)) | BDBM50434191 (CHEMBL2385278) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UA) Curated by ChEMBL | Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi... | ACS Med Chem Lett 4: 491-6 (2013) Article DOI: 10.1021/ml300410d BindingDB Entry DOI: 10.7270/Q2KP83J7 | |||||||||||
More data for this Ligand-Target Pair |
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