Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50407493 (CHEMBL5288446) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Relative potency against Histamine H1 receptor in rat aorta | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50369190 (CHEMBL4163133) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50407492 (CHEMBL5280732) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Apparent pA2 value of compound at 50 nM concentration of mepyramine in rat aorta | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50407464 (CHEMBL5289275) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | 2.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Apparent pA2 value of compound at 10 nM concentration of mepyramine in guinea pig ileum | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50407467 (CHEMBL5289169) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | 3.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami... | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50407491 (CHEMBL5282293) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami... | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686] (Homo sapiens (Human)) | BDBM50094484 (CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | US Patent | 8.31E+3 | -6.93 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50481595 (CHEMBL5287183) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | 4.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein (Homo sapiens (Human)) | BDBM50407461 (CHEMBL5274458) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | 4.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Tetsed for Antagonistic activity at histamine H3 receptor in guinea pig ileal longitudinal muscle in the presence of mepyramine at a concentration of... | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686] (Homo sapiens (Human)) | BDBM213748 (US9284299, PKF115-584 | US9738628, Compound PKF115...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 5.39E+4 | -5.82 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686] (Homo sapiens (Human)) | BDBM50094484 (CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | US Patent | 6.25E+4 | -5.73 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686] (Homo sapiens (Human)) | BDBM32102 (1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | US Patent | 6.62E+4 | -5.70 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686] (Homo sapiens (Human)) | BDBM213761 (US9284299, 12 | US9738628, Compound 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.71E+5 | -5.14 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686] (Homo sapiens (Human)) | BDBM32102 (1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | US Patent | 1.71E+5 | -5.13 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686] (Homo sapiens (Human)) | BDBM213761 (US9284299, 12 | US9738628, Compound 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.76E+5 | -5.12 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
University of Utah Research Foundation US Patent | Assay Description Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino... | US Patent US9284299 (2016) BindingDB Entry DOI: 10.7270/Q2WW7GGC | |||||||||||
More data for this Ligand-Target Pair |