Found 36 hits of ec50 for UniProtKB: Q9Y5X4 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192208
(2-chloro-N-(4-(5-(cyclopropanecarboxamido)-1H-benz...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CC3)cc2[nH]1 Show InChI InChI=1S/C24H19ClN4O2/c25-19-4-2-1-3-18(19)24(31)26-16-9-7-14(8-10-16)22-28-20-12-11-17(13-21(20)29-22)27-23(30)15-5-6-15/h1-4,7-13,15H,5-6H2,(H,26,31)(H,27,30)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192208
(2-chloro-N-(4-(5-(cyclopropanecarboxamido)-1H-benz...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CC3)cc2[nH]1 Show InChI InChI=1S/C24H19ClN4O2/c25-19-4-2-1-3-18(19)24(31)26-16-9-7-14(8-10-16)22-28-20-12-11-17(13-21(20)29-22)27-23(30)15-5-6-15/h1-4,7-13,15H,5-6H2,(H,26,31)(H,27,30)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 141 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192198
(2-chloro-N-(4-(5-isobutyramido-1H-benzo[d]imidazol...)Show SMILES CC(C)C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H21ClN4O2/c1-14(2)23(30)27-17-11-12-20-21(13-17)29-22(28-20)15-7-9-16(10-8-15)26-24(31)18-5-3-4-6-19(18)25/h3-14H,1-2H3,(H,26,31)(H,27,30)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 147 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192209
(2-chloro-N-(2-{4-[(2-fluorobenzene)amido]phenyl}-1...)Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C27H18ClFN4O2/c28-21-7-3-1-5-19(21)26(34)31-18-13-14-23-24(15-18)33-25(32-23)16-9-11-17(12-10-16)30-27(35)20-6-2-4-8-22(20)29/h1-15H,(H,30,35)(H,31,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192204
(2-chloro-N-(2-{4-[(2-methylbenzene)amido]phenyl}-1...)Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C28H21ClN4O2/c1-17-6-2-3-7-21(17)27(34)30-19-12-10-18(11-13-19)26-32-24-15-14-20(16-25(24)33-26)31-28(35)22-8-4-5-9-23(22)29/h2-16H,1H3,(H,30,34)(H,31,35)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192202
(2-chloro-N-(4-(5-((1S,2R)-2-fluorocyclopropanecarb...)Show SMILES F[C@@H]1C[C@H]1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H18ClFN4O2/c25-18-4-2-1-3-16(18)23(31)27-14-7-5-13(6-8-14)22-29-20-10-9-15(11-21(20)30-22)28-24(32)17-12-19(17)26/h1-11,17,19H,12H2,(H,27,31)(H,28,32)(H,29,30)/t17-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192210
(CHEMBL215539 | N-[2-(4-benzoylamino-phenyl)-1H-ben...)Show SMILES Clc1ccccc1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H19ClN4O2/c28-22-9-5-4-8-21(22)27(34)30-20-14-15-23-24(16-20)32-25(31-23)17-10-12-19(13-11-17)29-26(33)18-6-2-1-3-7-18/h1-16H,(H,29,33)(H,30,34)(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 270 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192209
(2-chloro-N-(2-{4-[(2-fluorobenzene)amido]phenyl}-1...)Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C27H18ClFN4O2/c28-21-7-3-1-5-19(21)26(34)31-18-13-14-23-24(15-18)33-25(32-23)16-9-11-17(12-10-16)30-27(35)20-6-2-4-8-22(20)29/h1-15H,(H,30,35)(H,31,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 270 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192198
(2-chloro-N-(4-(5-isobutyramido-1H-benzo[d]imidazol...)Show SMILES CC(C)C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H21ClN4O2/c1-14(2)23(30)27-17-11-12-20-21(13-17)29-22(28-20)15-7-9-16(10-8-15)26-24(31)18-5-3-4-6-19(18)25/h3-14H,1-2H3,(H,26,31)(H,27,30)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 316 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192204
(2-chloro-N-(2-{4-[(2-methylbenzene)amido]phenyl}-1...)Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C28H21ClN4O2/c1-17-6-2-3-7-21(17)27(34)30-19-12-10-18(11-13-19)26-32-24-15-14-20(16-25(24)33-26)31-28(35)22-8-4-5-9-23(22)29/h2-16H,1H3,(H,30,34)(H,31,35)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192207
(2-chloro-N-(4-(5-(1-phenylcyclopropanecarboxamido)...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3(CC3)c3ccccc3)cc2[nH]1 Show InChI InChI=1S/C30H23ClN4O2/c31-24-9-5-4-8-23(24)28(36)32-21-12-10-19(11-13-21)27-34-25-15-14-22(18-26(25)35-27)33-29(37)30(16-17-30)20-6-2-1-3-7-20/h1-15,18H,16-17H2,(H,32,36)(H,33,37)(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192210
(CHEMBL215539 | N-[2-(4-benzoylamino-phenyl)-1H-ben...)Show SMILES Clc1ccccc1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H19ClN4O2/c28-22-9-5-4-8-21(22)27(34)30-20-14-15-23-24(16-20)32-25(31-23)17-10-12-19(13-11-17)29-26(33)18-6-2-1-3-7-18/h1-16H,(H,29,33)(H,30,34)(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 610 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192202
(2-chloro-N-(4-(5-((1S,2R)-2-fluorocyclopropanecarb...)Show SMILES F[C@@H]1C[C@H]1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H18ClFN4O2/c25-18-4-2-1-3-16(18)23(31)27-14-7-5-13(6-8-14)22-29-20-10-9-15(11-21(20)30-22)28-24(32)17-12-19(17)26/h1-11,17,19H,12H2,(H,27,31)(H,28,32)(H,29,30)/t17-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 720 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192205
(2-chloro-N-(4-(5-(cyclobutanecarboxamido)-1H-benzo...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CCC3)cc2[nH]1 Show InChI InChI=1S/C25H21ClN4O2/c26-20-7-2-1-6-19(20)25(32)27-17-10-8-15(9-11-17)23-29-21-13-12-18(14-22(21)30-23)28-24(31)16-4-3-5-16/h1-2,6-14,16H,3-5H2,(H,27,32)(H,28,31)(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 986 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192201
(2-chloro-N-(4-(5-(cyclopentanecarboxamido)-1H-benz...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CCCC3)cc2[nH]1 Show InChI InChI=1S/C26H23ClN4O2/c27-21-8-4-3-7-20(21)26(33)28-18-11-9-16(10-12-18)24-30-22-14-13-19(15-23(22)31-24)29-25(32)17-5-1-2-6-17/h3-4,7-15,17H,1-2,5-6H2,(H,28,33)(H,29,32)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192205
(2-chloro-N-(4-(5-(cyclobutanecarboxamido)-1H-benzo...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CCC3)cc2[nH]1 Show InChI InChI=1S/C25H21ClN4O2/c26-20-7-2-1-6-19(20)25(32)27-17-10-8-15(9-11-17)23-29-21-13-12-18(14-22(21)30-23)28-24(31)16-4-3-5-16/h1-2,6-14,16H,3-5H2,(H,27,32)(H,28,31)(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192203
(2-chloro-N-(4-(5-(2,2-difluorocyclopropanecarboxam...)Show SMILES FC1(F)CC1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H17ClF2N4O2/c25-18-4-2-1-3-16(18)22(32)28-14-7-5-13(6-8-14)21-30-19-10-9-15(11-20(19)31-21)29-23(33)17-12-24(17,26)27/h1-11,17H,12H2,(H,28,32)(H,29,33)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192199
(2-chloro-N-(4-(5-(2-chlorobenzamido)-1H-benzo[d]im...)Show SMILES Clc1ccccc1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2cccnc2Cl)cc1 Show InChI InChI=1S/C26H17Cl2N5O2/c27-20-6-2-1-4-18(20)25(34)31-17-11-12-21-22(14-17)33-24(32-21)15-7-9-16(10-8-15)30-26(35)19-5-3-13-29-23(19)28/h1-14H,(H,30,35)(H,31,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192197
(2-chloro-N-(4-(5-(1-methylcyclopropanecarboxamido)...)Show SMILES CC1(CC1)C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H21ClN4O2/c1-25(12-13-25)24(32)28-17-10-11-20-21(14-17)30-22(29-20)15-6-8-16(9-7-15)27-23(31)18-4-2-3-5-19(18)26/h2-11,14H,12-13H2,1H3,(H,27,31)(H,28,32)(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192196
(2-chloro-N-(4-(5-pivalamido-1H-benzo[d]imidazol-2-...)Show SMILES CC(C)(C)C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H23ClN4O2/c1-25(2,3)24(32)28-17-12-13-20-21(14-17)30-22(29-20)15-8-10-16(11-9-15)27-23(31)18-6-4-5-7-19(18)26/h4-14H,1-3H3,(H,27,31)(H,28,32)(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.61E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192197
(2-chloro-N-(4-(5-(1-methylcyclopropanecarboxamido)...)Show SMILES CC1(CC1)C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H21ClN4O2/c1-25(12-13-25)24(32)28-17-10-11-20-21(14-17)30-22(29-20)15-6-8-16(9-7-15)27-23(31)18-4-2-3-5-19(18)26/h2-11,14H,12-13H2,1H3,(H,27,31)(H,28,32)(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192203
(2-chloro-N-(4-(5-(2,2-difluorocyclopropanecarboxam...)Show SMILES FC1(F)CC1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C24H17ClF2N4O2/c25-18-4-2-1-3-16(18)22(32)28-14-7-5-13(6-8-14)21-30-19-10-9-15(11-20(19)31-21)29-23(33)17-12-24(17,26)27/h1-11,17H,12H2,(H,28,32)(H,29,33)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192201
(2-chloro-N-(4-(5-(cyclopentanecarboxamido)-1H-benz...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3CCCC3)cc2[nH]1 Show InChI InChI=1S/C26H23ClN4O2/c27-21-8-4-3-7-20(21)26(33)28-18-11-9-16(10-12-18)24-30-22-14-13-19(15-23(22)31-24)29-25(32)17-5-1-2-6-17/h3-4,7-15,17H,1-2,5-6H2,(H,28,33)(H,29,32)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192213
(2-chloro-N-(2-(1-(4-fluorophenyl)-1H-pyrazol-4-yl)...)Show SMILES Fc1ccc(cc1)-n1cc(cn1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C23H15ClFN5O/c24-19-4-2-1-3-18(19)23(31)27-16-7-10-20-21(11-16)29-22(28-20)14-12-26-30(13-14)17-8-5-15(25)6-9-17/h1-13H,(H,27,31)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192211
(2-chloro-N-(3-{5-[(2-chlorobenzene)amido]-1H-1,3-b...)Show SMILES Clc1ccccc1C(=O)Nc1cccc(c1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C27H18Cl2N4O2/c28-21-10-3-1-8-19(21)26(34)30-17-7-5-6-16(14-17)25-32-23-13-12-18(15-24(23)33-25)31-27(35)20-9-2-4-11-22(20)29/h1-15H,(H,30,34)(H,31,35)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192200
(2-chloro-N-(2-(3,5-dichloro-2-hydroxyphenyl)-1H-be...)Show SMILES Oc1c(Cl)cc(Cl)cc1-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C20H12Cl3N3O2/c21-10-7-13(18(27)15(23)8-10)19-25-16-6-5-11(9-17(16)26-19)24-20(28)12-3-1-2-4-14(12)22/h1-9,27H,(H,24,28)(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192199
(2-chloro-N-(4-(5-(2-chlorobenzamido)-1H-benzo[d]im...)Show SMILES Clc1ccccc1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2cccnc2Cl)cc1 Show InChI InChI=1S/C26H17Cl2N5O2/c27-20-6-2-1-4-18(20)25(34)31-17-11-12-21-22(14-17)33-24(32-21)15-7-9-16(10-8-15)30-26(35)19-5-3-13-29-23(19)28/h1-14H,(H,30,35)(H,31,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192196
(2-chloro-N-(4-(5-pivalamido-1H-benzo[d]imidazol-2-...)Show SMILES CC(C)(C)C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc(NC(=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C25H23ClN4O2/c1-25(2,3)24(32)28-17-12-13-20-21(14-17)30-22(29-20)15-8-10-16(11-9-15)27-23(31)18-6-4-5-7-19(18)26/h4-14H,1-3H3,(H,27,31)(H,28,32)(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.27E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192206
(CHEMBL215363 | N-(2-(benzo[d][1,3]dioxol-5-yl)-1H-...)Show SMILES Clc1ccccc1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H14ClN3O3/c22-15-4-2-1-3-14(15)21(26)23-13-6-7-16-17(10-13)25-20(24-16)12-5-8-18-19(9-12)28-11-27-18/h1-10H,11H2,(H,23,26)(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192212
(2-chloro-N-(4-(5-(1-cyanocyclopropanecarboxamido)-...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3(CC3)C#N)cc2[nH]1 Show InChI InChI=1S/C25H18ClN5O2/c26-19-4-2-1-3-18(19)23(32)28-16-7-5-15(6-8-16)22-30-20-10-9-17(13-21(20)31-22)29-24(33)25(14-27)11-12-25/h1-10,13H,11-12H2,(H,28,32)(H,29,33)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by luciferase NCOR release assay in CHO cells |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192211
(2-chloro-N-(3-{5-[(2-chlorobenzene)amido]-1H-1,3-b...)Show SMILES Clc1ccccc1C(=O)Nc1cccc(c1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C27H18Cl2N4O2/c28-21-10-3-1-8-19(21)26(34)30-17-7-5-6-16(14-17)25-32-23-13-12-18(15-24(23)33-25)31-27(35)20-9-2-4-11-22(20)29/h1-15H,(H,30,34)(H,31,35)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192212
(2-chloro-N-(4-(5-(1-cyanocyclopropanecarboxamido)-...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3(CC3)C#N)cc2[nH]1 Show InChI InChI=1S/C25H18ClN5O2/c26-19-4-2-1-3-18(19)23(32)28-16-7-5-15(6-8-16)22-30-20-10-9-17(13-21(20)31-22)29-24(33)25(14-27)11-12-25/h1-10,13H,11-12H2,(H,28,32)(H,29,33)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192200
(2-chloro-N-(2-(3,5-dichloro-2-hydroxyphenyl)-1H-be...)Show SMILES Oc1c(Cl)cc(Cl)cc1-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C20H12Cl3N3O2/c21-10-7-13(18(27)15(23)8-10)19-25-16-6-5-11(9-17(16)26-19)24-20(28)12-3-1-2-4-14(12)22/h1-9,27H,(H,24,28)(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192207
(2-chloro-N-(4-(5-(1-phenylcyclopropanecarboxamido)...)Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1nc2ccc(NC(=O)C3(CC3)c3ccccc3)cc2[nH]1 Show InChI InChI=1S/C30H23ClN4O2/c31-24-9-5-4-8-23(24)28(36)32-21-12-10-19(11-13-21)27-34-25-15-14-22(18-26(25)35-27)33-29(37)30(16-17-30)20-6-2-1-3-7-20/h1-15,18H,16-17H2,(H,32,36)(H,33,37)(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192213
(2-chloro-N-(2-(1-(4-fluorophenyl)-1H-pyrazol-4-yl)...)Show SMILES Fc1ccc(cc1)-n1cc(cn1)-c1nc2ccc(NC(=O)c3ccccc3Cl)cc2[nH]1 Show InChI InChI=1S/C23H15ClFN5O/c24-19-4-2-1-3-18(19)23(31)27-16-7-10-20-21(11-16)29-22(28-20)14-12-26-30(13-14)17-8-5-15(25)6-9-17/h1-13H,(H,27,31)(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
Photoreceptor-specific nuclear receptor
(Homo sapiens (Human)) | BDBM50192206
(CHEMBL215363 | N-(2-(benzo[d][1,3]dioxol-5-yl)-1H-...)Show SMILES Clc1ccccc1C(=O)Nc1ccc2nc([nH]c2c1)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H14ClN3O3/c22-15-4-2-1-3-14(15)21(26)23-13-6-7-16-17(10-13)25-20(24-16)12-5-8-18-19(9-12)28-11-27-18/h1-10H,11H2,(H,23,26)(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Agonist activity at NR2E3 by beta lactamase transactivation assay |
Bioorg Med Chem Lett 16: 5001-4 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.056
BindingDB Entry DOI: 10.7270/Q280528D |
More data for this
Ligand-Target Pair | |
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