Compile Data Set for Download or QSAR

Found 520 hits Enz. Inhib. hit(s) with all data for entry = 1059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306357 (US10144742, Compound I-519) Show SMILES COc1cc(c(F)cn1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1nccn1C Show InChI InChI=1S/C28H24F2N6O2/c1-36-13-12-31-24(36)4-3-11-32-28(37)18-7-10-22-23(14-18)35-27(20-15-25(38-2)33-16-21(20)30)26(34-22)17-5-8-19(29)9-6-17/h5-10,12-16H,3-4,11H2,1-2H3,(H,32,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306358 (US10144742, Compound I-520) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1cc(Cl)ccc1F)C(=O)NCCCc1nnc[nH]1 Show InChI InChI=1S/C26H19ClF2N6O/c27-17-6-9-20(29)19(13-17)25-24(15-3-7-18(28)8-4-15)33-21-10-5-16(12-22(21)34-25)26(36)30-11-1-2-23-31-14-32-35-23/h3-10,12-14H,1-2,11H2,(H,30,36)(H,31,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM305985 (US10144742, Compound I-147) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1N1CCOCC1)C(=O)NCc1ccc2nccn2c1 Show InChI InChI=1S/C27H23FN6O2/c28-21-5-2-19(3-6-21)25-26(33-11-13-36-14-12-33)32-22-7-4-20(15-23(22)31-25)27(35)30-16-18-1-8-24-29-9-10-34(24)17-18/h1-10,15,17H,11-14,16H2,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306021 (US10144742, Compound I-183) Show SMILES COc1cccc(c1)-c1nc2cc(ccc2nc1N1CCCCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H30N6O2/c1-35-21-8-5-7-19(17-21)25-26(33-15-3-2-4-16-33)32-22-11-10-20(18-23(22)31-25)27(34)30-12-6-9-24-28-13-14-29-24/h5,7-8,10-11,13-14,17-18H,2-4,6,9,12,15-16H2,1H3,(H,28,29)(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306093 (US10144742, Compound I-255) Show SMILES Clc1ccc(cc1)-c1nc2cc(ccc2nc1N1CCC(CC1)N1CCOCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C30H34ClN7O2/c31-23-6-3-21(4-7-23)28-29(38-14-9-24(10-15-38)37-16-18-40-19-17-37)36-25-8-5-22(20-26(25)35-28)30(39)34-11-1-2-27-32-12-13-33-27/h3-8,12-13,20,24H,1-2,9-11,14-19H2,(H,32,33)(H,34,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306113 (US10144742, Compound I-275) Show SMILES O=C(NCCCn1ccnc1)c1ccc2nc(N3CCC4(CC3)OCCO4)c(nc2c1)-c1ccccc1 Show InChI InChI=1S/C28H30N6O3/c35-27(30-11-4-13-33-16-12-29-20-33)22-7-8-23-24(19-22)31-25(21-5-2-1-3-6-21)26(32-23)34-14-9-28(10-15-34)36-17-18-37-28/h1-3,5-8,12,16,19-20H,4,9-11,13-15,17-18H2,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306207 (US10144742, Compound I-369) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1ccc(Cl)c(c1)C(F)(F)F)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H20ClF4N5O/c29-21-9-5-17(14-20(21)28(31,32)33)26-25(16-3-7-19(30)8-4-16)37-22-10-6-18(15-23(22)38-26)27(39)36-11-1-2-24-34-12-13-35-24/h3-10,12-15H,1-2,11H2,(H,34,35)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306238 (US10144742, Compound I-400) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OC1CCCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C26H26FN5O2/c27-19-10-7-17(8-11-19)24-26(34-20-4-1-2-5-20)32-21-12-9-18(16-22(21)31-24)25(33)30-13-3-6-23-28-14-15-29-23/h7-12,14-16,20H,1-6,13H2,(H,28,29)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306240 (US10144742, Compound I-402) Show SMILES CCOc1nc2ccc(cc2nc1-c1ccc(Cl)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C23H22ClN5O2/c1-2-31-23-21(15-5-8-17(24)9-6-15)28-19-14-16(7-10-18(19)29-23)22(30)27-11-3-4-20-25-12-13-26-20/h5-10,12-14H,2-4,11H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306242 (US10144742, Compound I-404) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OC1CC2(CCN2)C1)C(=O)NCCCc1ncc[nH]1 |(10.52,5.64,;9.19,4.87,;9.19,3.33,;7.85,2.56,;6.52,3.33,;6.52,4.87,;7.85,5.64,;5.19,2.56,;3.85,3.33,;2.52,2.56,;1.18,3.33,;-.15,2.56,;-.15,1.02,;1.18,.25,;2.52,1.02,;3.85,.25,;5.19,1.02,;6.52,.25,;6.52,-1.29,;5.43,-2.38,;6.52,-3.46,;5.43,-4.55,;6.52,-5.64,;7.61,-4.55,;7.61,-2.38,;-1.48,3.33,;-1.48,4.87,;-2.82,2.56,;-4.15,3.33,;-5.48,2.56,;-6.82,3.33,;-8.15,2.56,;-9.62,3.04,;-10.52,1.79,;-9.62,.55,;-8.15,1.02,)| Show InChI InChI=1S/C27H27FN6O2/c28-19-6-3-17(4-7-19)24-26(36-20-15-27(16-20)9-11-32-27)34-21-8-5-18(14-22(21)33-24)25(35)31-10-1-2-23-29-12-13-30-23/h3-8,12-14,20,32H,1-2,9-11,15-16H2,(H,29,30)(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306244 (US10144742, Compound I-406) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1CCOCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H28FN5O3/c28-21-6-3-19(4-7-21)25-27(36-17-18-9-14-35-15-10-18)33-22-8-5-20(16-23(22)32-25)26(34)31-11-1-2-24-29-12-13-30-24/h3-8,12-13,16,18H,1-2,9-11,14-15,17H2,(H,29,30)(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306245 (US10144742, Compound I-407) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1(CCC1)[N+]#[C-])C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H25FN6O2/c1-29-27(11-3-12-27)17-36-26-24(18-5-8-20(28)9-6-18)33-22-16-19(7-10-21(22)34-26)25(35)32-13-2-4-23-30-14-15-31-23/h5-10,14-16H,2-4,11-13,17H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306247 (US10144742, Compound I-409) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCc1cccnc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H23FN6O2/c28-21-8-5-19(6-9-21)25-27(36-17-18-3-1-11-29-16-18)34-22-10-7-20(15-23(22)33-25)26(35)32-12-2-4-24-30-13-14-31-24/h1,3,5-11,13-16H,2,4,12,17H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306252 (US10144742, Compound I-414) Show SMILES CC(C)Oc1nc2ccc(cc2nc1-c1cc(ccc1F)C#N)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C25H23FN6O2/c1-15(2)34-25-23(18-12-16(14-27)5-7-19(18)26)31-21-13-17(6-8-20(21)32-25)24(33)30-9-3-4-22-28-10-11-29-22/h5-8,10-13,15H,3-4,9H2,1-2H3,(H,28,29)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306258 (US10144742, Compound I-420) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCCc1ccccc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C29H26FN5O2/c30-23-11-8-21(9-12-23)27-29(37-18-14-20-5-2-1-3-6-20)35-24-13-10-22(19-25(24)34-27)28(36)33-15-4-7-26-31-16-17-32-26/h1-3,5-6,8-13,16-17,19H,4,7,14-15,18H2,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306260 (US10144742, Compound I-422) Show SMILES Cc1cc(c(C)s1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H24FN5OS/c1-16-14-21(17(2)35-16)26-25(18-5-8-20(28)9-6-18)32-22-10-7-19(15-23(22)33-26)27(34)31-11-3-4-24-29-12-13-30-24/h5-10,12-15H,3-4,11H2,1-2H3,(H,29,30)(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306264 (US10144742, Compound I-426) Show SMILES COc1cc(ccc1F)-c1nc2cc(ccc2nc1OC(C)C)C(=O)NCc1ccc2nccn2c1 Show InChI InChI=1S/C27H24FN5O3/c1-16(2)36-27-25(18-5-7-20(28)23(13-18)35-3)31-22-12-19(6-8-21(22)32-27)26(34)30-14-17-4-9-24-29-10-11-33(24)15-17/h4-13,15-16H,14H2,1-3H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306265 (US10144742, Compound I-427) Show SMILES COC1CC(C1)Oc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 |(7.85,-5.71,;6.52,-4.94,;6.52,-3.4,;5.43,-2.31,;6.52,-1.22,;7.61,-2.31,;6.52,.32,;5.19,1.09,;3.85,.32,;2.52,1.09,;1.18,.32,;-.15,1.09,;-.15,2.63,;1.18,3.4,;2.52,2.63,;3.85,3.4,;5.19,2.63,;6.52,3.4,;7.85,2.63,;9.19,3.4,;9.19,4.94,;10.52,5.71,;7.85,5.71,;6.52,4.94,;-1.48,3.4,;-1.48,4.94,;-2.82,2.63,;-4.15,3.4,;-5.48,2.63,;-6.82,3.4,;-8.15,2.63,;-8.15,1.09,;-9.62,.61,;-10.52,1.86,;-9.62,3.1,)| Show InChI InChI=1S/C26H26FN5O3/c1-34-19-14-20(15-19)35-26-24(16-4-7-18(27)8-5-16)31-22-13-17(6-9-21(22)32-26)25(33)30-10-2-3-23-28-11-12-29-23/h4-9,11-13,19-20H,2-3,10,14-15H2,1H3,(H,28,29)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306268 (US10144742, Compound I-430) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OC1CCCNC1)C(=O)NCCCc1ncc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306273 (US10144742, Compound I-435) Show SMILES CC(C)Oc1nc2ccc(cc2nc1-c1ccc(F)c(Cl)c1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C24H23ClFN5O2/c1-14(2)33-24-22(15-5-7-18(26)17(25)12-15)30-20-13-16(6-8-19(20)31-24)23(32)29-9-3-4-21-27-10-11-28-21/h5-8,10-14H,3-4,9H2,1-2H3,(H,27,28)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306276 (US10144742, Compound I-438) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1CCCO1)C(=O)NCCCc1ncc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306277 (US10144742, Compound I-439) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCc1ccccc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H24FN5O2/c29-22-11-8-20(9-12-22)26-28(36-18-19-5-2-1-3-6-19)34-23-13-10-21(17-24(23)33-26)27(35)32-14-4-7-25-30-15-16-31-25/h1-3,5-6,8-13,15-17H,4,7,14,18H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306278 (US10144742, Compound I-440) Show SMILES CCOc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C23H22FN5O2/c1-2-31-23-21(15-5-8-17(24)9-6-15)28-19-14-16(7-10-18(19)29-23)22(30)27-11-3-4-20-25-12-13-26-20/h5-10,12-14H,2-4,11H2,1H3,(H,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306280 (US10144742, Compound I-442) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCCc1cn[nH]c1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C26H24FN7O2/c27-20-6-3-18(4-7-20)24-26(36-13-9-17-15-31-32-16-17)34-21-8-5-19(14-22(21)33-24)25(35)30-10-1-2-23-28-11-12-29-23/h3-8,11-12,14-16H,1-2,9-10,13H2,(H,28,29)(H,30,35)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306283 (US10144742, Compound I-445) Show SMILES Cc1ccc(cc1-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1)C(F)(F)F Show InChI InChI=1S/C29H23F4N5O/c1-17-4-8-20(29(31,32)33)16-22(17)27-26(18-5-9-21(30)10-6-18)37-23-11-7-19(15-24(23)38-27)28(39)36-12-2-3-25-34-13-14-35-25/h4-11,13-16H,2-3,12H2,1H3,(H,34,35)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306284 (US10144742, Compound I-446) Show SMILES Cc1noc(C)c1COc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H25FN6O3/c1-16-21(17(2)37-34-16)15-36-27-25(18-5-8-20(28)9-6-18)32-23-14-19(7-10-22(23)33-27)26(35)31-11-3-4-24-29-12-13-30-24/h5-10,12-14H,3-4,11,15H2,1-2H3,(H,29,30)(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306285 (US10144742, Compound I-447) Show SMILES CCOc1cccc(c1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C29H26FN5O2/c1-2-37-23-6-3-5-20(17-23)28-27(19-8-11-22(30)12-9-19)34-24-13-10-21(18-25(24)35-28)29(36)33-14-4-7-26-31-15-16-32-26/h3,5-6,8-13,15-18H,2,4,7,14H2,1H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306288 (US10144742, Compound I-450) Show SMILES Cc1ccc(C)c(c1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C29H26FN5O/c1-18-5-6-19(2)23(16-18)28-27(20-7-10-22(30)11-8-20)34-24-12-9-21(17-25(24)35-28)29(36)33-13-3-4-26-31-14-15-32-26/h5-12,14-17H,3-4,13H2,1-2H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306289 (US10144742, Compound I-451) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1cc(ccc1F)C(F)(F)F)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H20F5N5O/c29-19-7-3-16(4-8-19)25-26(20-15-18(28(31,32)33)6-9-21(20)30)38-23-14-17(5-10-22(23)37-25)27(39)36-11-1-2-24-34-12-13-35-24/h3-10,12-15H,1-2,11H2,(H,34,35)(H,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306292 (US10144742, Compound I-454) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCc1ccccc1Cl)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H23ClFN5O2/c29-22-5-2-1-4-20(22)17-37-28-26(18-7-10-21(30)11-8-18)34-24-16-19(9-12-23(24)35-28)27(36)33-13-3-6-25-31-14-15-32-25/h1-2,4-5,7-12,14-16H,3,6,13,17H2,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306294 (US10144742, Compound I-456) Show SMILES CN(C)C1CCC(CC1)Oc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 |(7.85,-6.16,;6.52,-5.39,;5.19,-6.16,;6.52,-3.85,;5.19,-3.08,;5.19,-1.54,;6.52,-.77,;7.85,-1.54,;7.85,-3.08,;6.52,.77,;5.19,1.54,;3.85,.77,;2.52,1.54,;1.18,.77,;-.15,1.54,;-.15,3.08,;1.18,3.85,;2.52,3.08,;3.85,3.85,;5.19,3.08,;6.52,3.85,;7.85,3.08,;9.19,3.85,;9.19,5.39,;10.52,6.16,;7.85,6.16,;6.52,5.39,;-1.48,3.85,;-1.48,5.39,;-2.82,3.08,;-4.15,3.85,;-5.48,3.08,;-6.82,3.85,;-8.15,3.08,;-8.15,1.54,;-9.62,1.06,;-10.52,2.31,;-9.62,3.56,)| Show InChI InChI=1S/C29H33FN6O2/c1-36(2)22-10-12-23(13-11-22)38-29-27(19-5-8-21(30)9-6-19)34-25-18-20(7-14-24(25)35-29)28(37)33-15-3-4-26-31-16-17-32-26/h5-9,14,16-18,22-23H,3-4,10-13,15H2,1-2H3,(H,31,32)(H,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306295 (US10144742, Compound I-457) Show SMILES COC1CCN(C1)c1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306298 (US10144742, Compound I-460) Show SMILES Cn1ccc(COc2nc3ccc(cc3nc2-c2ccc(F)cc2)C(=O)NCCCc2ncc[nH]2)n1 Show InChI InChI=1S/C26H24FN7O2/c1-34-14-10-20(33-34)16-36-26-24(17-4-7-19(27)8-5-17)31-22-15-18(6-9-21(22)32-26)25(35)30-11-2-3-23-28-12-13-29-23/h4-10,12-15H,2-3,11,16H2,1H3,(H,28,29)(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306300 (US10144742, Compound I-462) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC#C)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C24H20FN5O2/c1-2-14-32-24-22(16-5-8-18(25)9-6-16)29-20-15-17(7-10-19(20)30-24)23(31)28-11-3-4-21-26-12-13-27-21/h1,5-10,12-13,15H,3-4,11,14H2,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306301 (US10144742, Compound I-463) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1cccc(Cl)c1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H21ClFN5O/c28-20-4-1-3-18(15-20)26-25(17-6-9-21(29)10-7-17)33-22-11-8-19(16-23(22)34-26)27(35)32-12-2-5-24-30-13-14-31-24/h1,3-4,6-11,13-16H,2,5,12H2,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306302 (US10144742, Compound I-464) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCc1nc2cnccc2[nH]1 Show InChI InChI=1S/C28H18F2N6O/c29-19-6-1-16(2-7-19)26-27(17-3-8-20(30)9-4-17)36-23-13-18(5-10-21(23)35-26)28(37)32-15-25-33-22-11-12-31-14-24(22)34-25/h1-14H,15H2,(H,32,37)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306303 (US10144742, Compound I-465) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1N1CCCC1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C25H25FN6O/c26-19-8-5-17(6-9-19)23-24(32-14-1-2-15-32)31-20-10-7-18(16-21(20)30-23)25(33)29-11-3-4-22-27-12-13-28-22/h5-10,12-13,16H,1-4,11,14-15H2,(H,27,28)(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306304 (US10144742, Compound I-466) Show SMILES COc1cc(c(F)cn1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H22F2N6O2/c1-37-24-14-19(20(29)15-33-24)26-25(16-4-7-18(28)8-5-16)34-21-9-6-17(13-22(21)35-26)27(36)32-10-2-3-23-30-11-12-31-23/h4-9,11-15H,2-3,10H2,1H3,(H,30,31)(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306305 (US10144742, Compound I-467) Show SMILES COc1ccc(C)c(c1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C29H26FN5O2/c1-18-5-11-22(37-2)17-23(18)28-27(19-6-9-21(30)10-7-19)34-24-12-8-20(16-25(24)35-28)29(36)33-13-3-4-26-31-14-15-32-26/h5-12,14-17H,3-4,13H2,1-2H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306306 (US10144742, Compound I-468) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1O[C@H]1CCOC1)C(=O)NCCCc1ncc[nH]1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306307 (US10144742, Compound I-469) Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCc1nccs1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C25H21FN6O2S/c26-18-6-3-16(4-7-18)23-25(34-15-22-29-12-13-35-22)32-19-8-5-17(14-20(19)31-23)24(33)30-9-1-2-21-27-10-11-28-21/h3-8,10-14H,1-2,9,15H2,(H,27,28)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306309 (US10144742, Compound I-471) Show SMILES Cc1cc(ccc1F)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H23F2N5O/c1-17-15-19(6-10-22(17)30)27-26(18-4-8-21(29)9-5-18)34-23-11-7-20(16-24(23)35-27)28(36)33-12-2-3-25-31-13-14-32-25/h4-11,13-16H,2-3,12H2,1H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306310 (US10144742, Compound I-472) Show SMILES Cc1ccc(cc1-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1)C#N Show InChI InChI=1S/C29H23FN6O/c1-18-4-5-19(17-31)15-23(18)28-27(20-6-9-22(30)10-7-20)35-24-11-8-21(16-25(24)36-28)29(37)34-12-2-3-26-32-13-14-33-26/h4-11,13-16H,2-3,12H2,1H3,(H,32,33)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306315 (US10144742, Compound I-477) Show SMILES O=C(NCCCc1ncc[nH]1)c1ccc2nc(-c3ccccc3)c(nc2c1)-c1cccs1 Show InChI InChI=1S/C25H21N5OS/c31-25(28-12-4-9-22-26-13-14-27-22)18-10-11-19-20(16-18)30-24(21-8-5-15-32-21)23(29-19)17-6-2-1-3-7-17/h1-3,5-8,10-11,13-16H,4,9,12H2,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306316 (US10144742, Compound I-478) Show SMILES CC(C)COc1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C25H26FN5O2/c1-16(2)15-33-25-23(17-5-8-19(26)9-6-17)30-21-14-18(7-10-20(21)31-25)24(32)29-11-3-4-22-27-12-13-28-22/h5-10,12-14,16H,3-4,11,15H2,1-2H3,(H,27,28)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306318 (US10144742, Compound I-480) Show SMILES Fc1ccc(cc1)-c1nc2ccc(cc2nc1-c1cc(Cl)ccc1F)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C27H20ClF2N5O/c28-18-6-9-21(30)20(15-18)26-25(16-3-7-19(29)8-4-16)34-22-10-5-17(14-23(22)35-26)27(36)33-11-1-2-24-31-12-13-32-24/h3-10,12-15H,1-2,11H2,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306319 (US10144742, Compound I-481) Show SMILES COc1ccc(F)c(c1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H23F2N5O2/c1-37-20-9-10-22(30)21(16-20)27-26(17-4-7-19(29)8-5-17)34-23-11-6-18(15-24(23)35-27)28(36)33-12-2-3-25-31-13-14-32-25/h4-11,13-16H,2-3,12H2,1H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306322 (US10144742, Compound I-484) Show SMILES COc1cccc(c1)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H24FN5O2/c1-36-22-5-2-4-19(16-22)27-26(18-7-10-21(29)11-8-18)33-23-12-9-20(17-24(23)34-27)28(35)32-13-3-6-25-30-14-15-31-25/h2,4-5,7-12,14-17H,3,6,13H2,1H3,(H,30,31)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306323 (US10144742, Compound I-485) Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1nc2ccc(cc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ccc(N)nc1 |r| Show InChI InChI=1S/C29H31FN6O2/c1-18-16-36(17-19(2)38-18)28-27(21-6-9-23(30)10-7-21)34-25-14-22(8-11-24(25)35-28)29(37)32-13-3-4-20-5-12-26(31)33-15-20/h5-12,14-15,18-19H,3-4,13,16-17H2,1-2H3,(H2,31,33)(H,32,37)/t18-,19+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM306326 (US10144742, Compound I-488) Show SMILES COc1cc(ccc1F)-c1nc2cc(ccc2nc1-c1ccc(F)cc1)C(=O)NCCCc1ncc[nH]1 Show InChI InChI=1S/C28H23F2N5O2/c1-37-24-16-18(6-10-21(24)30)27-26(17-4-8-20(29)9-5-17)34-22-11-7-19(15-23(22)35-27)28(36)33-12-2-3-25-31-13-14-32-25/h4-11,13-16H,2-3,12H2,1H3,(H,31,32)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				US Patent US10144742 (2018) BindingDB Entry DOI: 10.7270/Q2NV9M91
					More data for this Ligand-Target Pair

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