Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26673 (6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dih...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26674 (6-(2-hydroxy-5-methylphenyl)-2-oxo-4-phenyl-1,2-di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26675 (4-(2-hydroxy-5-methylphenyl)-2-oxo-6-phenyl-1,2-di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26676 (6-(2-hydroxyphenyl)-4-(4-hydroxyphenyl)-2-oxo-1,2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26684 (4-oxo-6-(thiophen-2-yl)-9-oxa-3-azatricyclo[8.4.0....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26685 (6-(furan-2-yl)-4-oxo-9-oxa-3-azatricyclo[8.4.0.0^{...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 870 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26686 (6-(4-chlorophenyl)-4-oxo-9-oxa-3-azatricyclo[8.4.0...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26679 (2-oxo-4,6-bis(thiophen-2-yl)-1,2-dihydropyridine-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26677 (4-(3-chlorophenyl)-6-(5-ethyl-2-hydroxyphenyl)-2-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26678 (6-(3-bromo-4-methoxyphenyl)-2-oxo-4-(trifluorometh...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26687 (6-(2-chlorophenyl)-4-oxo-9-oxa-3-azatricyclo[8.4.0...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26691 (4-oxo-6-(thiophen-2-yl)-9-thia-3-azatricyclo[8.4.0...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26683 (2-{3-amino-4-phenyl-1H-pyrazolo[3,4-b]pyridin-6-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.77E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26680 (2-oxo-4-(thiophen-2-yl)-6-(trifluoromethyl)-1,2-di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.54E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26682 (2-amino-6-(4-hydroxyphenyl)-4-phenylpyridine-3-car...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.41E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26692 (4-oxo-6-(pyridin-3-yl)-9-thia-3-azatricyclo[8.4.0....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.79E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26681 (6-(furan-2-yl)-2-oxo-4-(trifluoromethyl)-1,2-dihyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26695 (4-oxo-6-(pyridin-4-yl)-3-azatricyclo[8.4.0.0^{2,7}...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26694 (6-(4-fluorophenyl)-4-oxo-9-thia-3-azatricyclo[8.4....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26693 (6-(2-chlorophenyl)-4-oxo-9-thia-3-azatricyclo[8.4....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26689 (2-keto-4-(4-pyridyl)-1,5-dihydrochromeno[4,3-b]pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26688 (6-(4-methoxyphenyl)-4-oxo-9-oxa-3-azatricyclo[8.4....) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26696 (ethyl 3-methyl-4,8-dioxo-9-oxa-3-azatricyclo[8.4.0...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM26690 (4-oxo-6-(pyridin-2-yl)-9-oxa-3-azatricyclo[8.4.0.0...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Valeant Pharmaceuticals Research and Development | Assay Description PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was... | Bioorg Med Chem Lett 17: 1679-83 (2007) Article DOI: 10.1016/j.bmcl.2006.12.086 BindingDB Entry DOI: 10.7270/Q2CV4G2V | |||||||||||
More data for this Ligand-Target Pair |