Compile Data Set for Download or QSAR

Found 133 hits Enz. Inhib. hit(s) with all data for entry = 50026621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262625 (CHEMBL476312 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...) Show SMILES CS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H22N2O2S/c1-23(21,22)20(17-11-12-19-13-17)14-16-9-5-6-10-18(16)15-7-3-2-4-8-15/h2-10,17,19H,11-14H2,1H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262626 (CHEMBL515936 | Ethanesulfonic acid biphenyl-2-ylme...) Show SMILES CCS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C19H24N2O2S/c1-2-24(22,23)21(18-12-13-20-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,20H,2,12-15H2,1H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262415 ((S)-N-(biphenyl-2-ylmethyl)-N-(pyrrolidin-3-yl)iso...) Show SMILES CC(C)C(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O/c1-16(2)21(24)23(19-12-13-22-14-19)15-18-10-6-7-11-20(18)17-8-4-3-5-9-17/h3-11,16,19,22H,12-15H2,1-2H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262627 (CHEMBL476313 | Propane-1-sulfonic acid biphenyl-2-...) Show SMILES CCCS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H26N2O2S/c1-2-14-25(23,24)22(19-12-13-21-15-19)16-18-10-6-7-11-20(18)17-8-4-3-5-9-17/h3-11,19,21H,2,12-16H2,1H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262678 ((S)-ethyl biphenyl-2-ylmethyl(pyrrolidin-3-yl)carb...) Show SMILES CCOC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O2/c1-2-24-20(23)22(18-12-13-21-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,21H,2,12-15H2,1H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262684 (CHEMBL514232 | N-(1,1'-biphenyl-2-ylmethyl)-N',N'-...) Show SMILES CN(C)S(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C19H25N3O2S/c1-21(2)25(23,24)22(18-12-13-20-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,20H,12-15H2,1-2H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262679 (CHEMBL478835 | Propane-2-sulfonic acid biphenyl-2-...) Show SMILES CC(C)S(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H26N2O2S/c1-16(2)25(23,24)22(19-12-13-21-14-19)15-18-10-6-7-11-20(18)17-8-4-3-5-9-17/h3-11,16,19,21H,12-15H2,1-2H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262729 (Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-carbamic a...) Show SMILES CC(C)OC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O2/c1-16(2)25-21(24)23(19-12-13-22-14-19)15-18-10-6-7-11-20(18)17-8-4-3-5-9-17/h3-11,16,19,22H,12-15H2,1-2H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262630 (Biphenyl-2-ylmethyl-(R)-pyrrolidin-3-yl-carbamic a...) Show SMILES CCOC(=O)N(Cc1ccccc1-c1ccccc1)[C@@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O2/c1-2-24-20(23)22(18-12-13-21-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,21H,2,12-15H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262677 (Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-carbamic a...) Show SMILES COC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C19H22N2O2/c1-23-19(22)21(17-11-12-20-13-17)14-16-9-5-6-10-18(16)15-7-3-2-4-8-15/h2-10,17,20H,11-14H2,1H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262733 ((2-Phenoxy-benzyl)-(S)-pyrrolidin-3-yl-carbamic ac...) Show SMILES CCOC(=O)N(Cc1ccccc1Oc1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O3/c1-2-24-20(23)22(17-12-13-21-14-17)15-16-8-6-7-11-19(16)25-18-9-4-3-5-10-18/h3-11,17,21H,2,12-15H2,1H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262619 (CHEMBL507723 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...) Show SMILES CCCC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O/c1-2-8-21(24)23(19-13-14-22-15-19)16-18-11-6-7-12-20(18)17-9-4-3-5-10-17/h3-7,9-12,19,22H,2,8,13-16H2,1H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262624 (CHEMBL477148 | Pyrrolidine-1-carboxylic acid biphe...) Show SMILES O=C(N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1)N1CCCC1 |r| Show InChI InChI=1S/C22H27N3O/c26-22(24-14-6-7-15-24)25(20-12-13-23-16-20)17-19-10-4-5-11-21(19)18-8-2-1-3-9-18/h1-5,8-11,20,23H,6-7,12-17H2/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262631 (CHEMBL478622 | N-Biphenyl-2-ylmethyl-N-(R)-pyrroli...) Show SMILES CS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@@H]1CCNC1 |r| Show InChI InChI=1S/C18H22N2O2S/c1-23(21,22)20(17-11-12-19-13-17)14-16-9-5-6-10-18(16)15-7-3-2-4-8-15/h2-10,17,19H,11-14H2,1H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262728 (CHEMBL477782 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...) Show SMILES CCC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O/c1-2-20(23)22(18-12-13-21-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,21H,2,12-15H2,1H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262620 (CHEMBL476941 | N-Biphenyl-2-ylmethyl-3-methyl-N-(S...) Show SMILES CC(C)CC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C22H28N2O/c1-17(2)14-22(25)24(20-12-13-23-15-20)16-19-10-6-7-11-21(19)18-8-4-3-5-9-18/h3-11,17,20,23H,12-16H2,1-2H3/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262680 (CHEMBL477571 | N-Biphenyl-2-ylmethyl-C,C,C-trifluo...) Show SMILES FC(F)(F)S(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H19F3N2O2S/c19-18(20,21)26(24,25)23(16-10-11-22-12-16)13-15-8-4-5-9-17(15)14-6-2-1-3-7-14/h1-9,16,22H,10-13H2/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262676 ((S)-N-(2-phenoxybenzyl)-N-(pyrrolidin-3-yl)isobuty...) Show SMILES CC(C)C(=O)N(Cc1ccccc1Oc1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O2/c1-16(2)21(24)23(18-12-13-22-14-18)15-17-8-6-7-11-20(17)25-19-9-4-3-5-10-19/h3-11,16,18,22H,12-15H2,1-2H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262731 ((S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-car...) Show SMILES CCOC(=O)N(Cc1ccccc1C(F)(F)F)[C@H]1CCNC1 |r| Show InChI InChI=1S/C15H19F3N2O2/c1-2-22-14(21)20(12-7-8-19-9-12)10-11-5-3-4-6-13(11)15(16,17)18/h3-6,12,19H,2,7-10H2,1H3/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262730 ((2-Isopropyl-benzyl)-(S)-pyrrolidin-3-yl-carbamic ...) Show SMILES CCOC(=O)N(Cc1ccccc1C(C)C)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H26N2O2/c1-4-21-17(20)19(15-9-10-18-11-15)12-14-7-5-6-8-16(14)13(2)3/h5-8,13,15,18H,4,9-12H2,1-3H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262675 ((S)-N-(2-(methylthio)benzyl)-N-(pyrrolidin-3-yl)is...) Show SMILES CSc1ccccc1CN([C@H]1CCNC1)C(=O)C(C)C |r| Show InChI InChI=1S/C16H24N2OS/c1-12(2)16(19)18(14-8-9-17-10-14)11-13-6-4-5-7-15(13)20-3/h4-7,12,14,17H,8-11H2,1-3H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262734 (1-Biphenyl-2-ylmethyl-3,3-dimethyl-1-(S)-pyrrolidi...) Show SMILES CN(C)C(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H25N3O/c1-22(2)20(24)23(18-12-13-21-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,21H,12-15H2,1-2H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262674 (CHEMBL476527 | N-(S)-Pyrrolidin-3-yl-N-(2-trifluor...) Show SMILES CC(C)C(=O)N(Cc1ccccc1C(F)(F)F)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H21F3N2O/c1-11(2)15(22)21(13-7-8-20-9-13)10-12-5-3-4-6-14(12)16(17,18)19/h3-6,11,13,20H,7-10H2,1-2H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262675 ((S)-N-(2-(methylthio)benzyl)-N-(pyrrolidin-3-yl)is...) Show SMILES CSc1ccccc1CN([C@H]1CCNC1)C(=O)C(C)C |r| Show InChI InChI=1S/C16H24N2OS/c1-12(2)16(19)18(14-8-9-17-10-14)11-13-6-4-5-7-15(13)20-3/h4-7,12,14,17H,8-11H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262621 (CHEMBL476942 | N-(2-Isopropyl-benzyl)-N-(S)-pyrrol...) Show SMILES CC(C)C(=O)N(Cc1ccccc1C(C)C)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H28N2O/c1-13(2)17-8-6-5-7-15(17)12-20(18(21)14(3)4)16-9-10-19-11-16/h5-8,13-14,16,19H,9-12H2,1-4H3/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262622 (CHEMBL450435 | N-(2-Cyclopropyl-benzyl)-N-(S)-pyrr...) Show SMILES CC(C)C(=O)N(Cc1ccccc1C1CC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H26N2O/c1-13(2)18(21)20(16-9-10-19-11-16)12-15-5-3-4-6-17(15)14-7-8-14/h3-6,13-14,16,19H,7-12H2,1-2H3/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262681 ((S)-N-(2-(trifluoromethyl)benzyl)-N-(pyrrolidin-3-...) Show SMILES CS(=O)(=O)N(Cc1ccccc1C(F)(F)F)[C@H]1CCNC1 |r| Show InChI InChI=1S/C13H17F3N2O2S/c1-21(19,20)18(11-6-7-17-8-11)9-10-4-2-3-5-12(10)13(14,15)16/h2-5,11,17H,6-9H2,1H3/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262682 (CHEMBL477572 | N-(2-Methylsulfanyl-benzyl)-N-(S)-p...) Show SMILES CSc1ccccc1CN([C@H]1CCNC1)S(C)(=O)=O |r| Show InChI InChI=1S/C13H20N2O2S2/c1-18-13-6-4-3-5-11(13)10-15(19(2,16)17)12-7-8-14-9-12/h3-6,12,14H,7-10H2,1-2H3/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262732 ((2-Methylsulfanyl-benzyl)-(S)-pyrrolidin-3-yl-carb...) Show SMILES CCOC(=O)N(Cc1ccccc1SC)[C@H]1CCNC1 |r| Show InChI InChI=1S/C15H22N2O2S/c1-3-19-15(18)17(13-8-9-16-10-13)11-12-6-4-5-7-14(12)20-2/h4-7,13,16H,3,8-11H2,1-2H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262683 (CHEMBL477573 | N-(2-Phenoxy-benzyl)-N-(S)-pyrrolid...) Show SMILES CS(=O)(=O)N(Cc1ccccc1Oc1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H22N2O3S/c1-24(21,22)20(16-11-12-19-13-16)14-15-7-5-6-10-18(15)23-17-8-3-2-4-9-17/h2-10,16,19H,11-14H2,1H3/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262726 (CHEMBL449235 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...) Show SMILES O=CN(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H20N2O/c21-14-20(17-10-11-19-12-17)13-16-8-4-5-9-18(16)15-6-2-1-3-7-15/h1-9,14,17,19H,10-13H2/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262727 (CHEMBL479044 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...) Show SMILES CC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C19H22N2O/c1-15(22)21(18-11-12-20-13-18)14-17-9-5-6-10-19(17)16-7-3-2-4-8-16/h2-10,18,20H,11-14H2,1H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262622 (CHEMBL450435 | N-(2-Cyclopropyl-benzyl)-N-(S)-pyrr...) Show SMILES CC(C)C(=O)N(Cc1ccccc1C1CC1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H26N2O/c1-13(2)18(21)20(16-9-10-19-11-16)12-15-5-3-4-6-17(15)14-7-8-14/h3-6,13-14,16,19H,7-12H2,1-2H3/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262674 (CHEMBL476527 | N-(S)-Pyrrolidin-3-yl-N-(2-trifluor...) Show SMILES CC(C)C(=O)N(Cc1ccccc1C(F)(F)F)[C@H]1CCNC1 |r| Show InChI InChI=1S/C16H21F3N2O/c1-11(2)15(22)21(13-7-8-20-9-13)10-12-5-3-4-6-14(12)16(17,18)19/h3-6,11,13,20H,7-10H2,1-2H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262676 ((S)-N-(2-phenoxybenzyl)-N-(pyrrolidin-3-yl)isobuty...) Show SMILES CC(C)C(=O)N(Cc1ccccc1Oc1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O2/c1-16(2)21(24)23(18-12-13-22-14-18)15-17-8-6-7-11-20(17)25-19-9-4-3-5-10-19/h3-11,16,18,22H,12-15H2,1-2H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262725 (Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine | CH...) Show SMILES C(N[C@H]1CCNC1)c1ccccc1-c1ccccc1 |r| Show InChI InChI=1S/C17H20N2/c1-2-6-14(7-3-1)17-9-5-4-8-15(17)12-19-16-10-11-18-13-16/h1-9,16,18-19H,10-13H2/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	271	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262732 ((2-Methylsulfanyl-benzyl)-(S)-pyrrolidin-3-yl-carb...) Show SMILES CCOC(=O)N(Cc1ccccc1SC)[C@H]1CCNC1 |r| Show InChI InChI=1S/C15H22N2O2S/c1-3-19-15(18)17(13-8-9-16-10-13)11-12-6-4-5-7-14(12)20-2/h4-7,13,16H,3,8-11H2,1-2H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	353	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262630 (Biphenyl-2-ylmethyl-(R)-pyrrolidin-3-yl-carbamic a...) Show SMILES CCOC(=O)N(Cc1ccccc1-c1ccccc1)[C@@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O2/c1-2-24-20(23)22(18-12-13-21-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,21H,2,12-15H2,1H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262620 (CHEMBL476941 | N-Biphenyl-2-ylmethyl-3-methyl-N-(S...) Show SMILES CC(C)CC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C22H28N2O/c1-17(2)14-22(25)24(20-12-13-23-15-20)16-19-10-6-7-11-21(19)18-8-4-3-5-9-18/h3-11,17,20,23H,12-16H2,1-2H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	415	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262731 ((S)-Pyrrolidin-3-yl-(2-trifluoromethyl-benzyl)-car...) Show SMILES CCOC(=O)N(Cc1ccccc1C(F)(F)F)[C@H]1CCNC1 |r| Show InChI InChI=1S/C15H19F3N2O2/c1-2-22-14(21)20(12-7-8-19-9-12)10-11-5-3-4-6-13(11)15(16,17)18/h3-6,12,19H,2,7-10H2,1H3/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262733 ((2-Phenoxy-benzyl)-(S)-pyrrolidin-3-yl-carbamic ac...) Show SMILES CCOC(=O)N(Cc1ccccc1Oc1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O3/c1-2-24-20(23)22(17-12-13-21-14-17)15-16-8-6-7-11-19(16)25-18-9-4-3-5-10-18/h3-11,17,21H,2,12-15H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	444	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262629 (CHEMBL478623 | Ethanesulfonic acid biphenyl-2-ylme...) Show SMILES CCS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCN(C)C1 |r| Show InChI InChI=1S/C20H26N2O2S/c1-3-25(23,24)22(19-13-14-21(2)16-19)15-18-11-7-8-12-20(18)17-9-5-4-6-10-17/h4-12,19H,3,13-16H2,1-2H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	466	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262621 (CHEMBL476942 | N-(2-Isopropyl-benzyl)-N-(S)-pyrrol...) Show SMILES CC(C)C(=O)N(Cc1ccccc1C(C)C)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H28N2O/c1-13(2)17-8-6-5-7-15(17)12-20(18(21)14(3)4)16-9-10-19-11-16/h5-8,13-14,16,19H,9-12H2,1-4H3/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	544	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50262678 ((S)-ethyl biphenyl-2-ylmethyl(pyrrolidin-3-yl)carb...) Show SMILES CCOC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C20H24N2O2/c1-2-24-20(23)22(18-12-13-21-14-18)15-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18,21H,2,12-15H2,1H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	635	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of muscarinic M3 receptor (unknown origin)				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262619 (CHEMBL507723 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...) Show SMILES CCCC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O/c1-2-8-21(24)23(19-13-14-22-15-19)16-18-11-6-7-12-20(18)17-9-4-3-5-10-17/h3-7,9-12,19,22H,2,8,13-16H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50262628 (CHEMBL476315 | N-Biphenyl-2-ylmethyl-N-((S)-1-meth...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1-c1ccccc1)S(C)(=O)=O |r| Show InChI InChI=1S/C19H24N2O2S/c1-20-13-12-18(15-20)21(24(2,22)23)14-17-10-6-7-11-19(17)16-8-4-3-5-9-16/h3-11,18H,12-15H2,1-2H3/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	748	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine reuptake at human NET expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262730 ((2-Isopropyl-benzyl)-(S)-pyrrolidin-3-yl-carbamic ...) Show SMILES CCOC(=O)N(Cc1ccccc1C(C)C)[C@H]1CCNC1 |r| Show InChI InChI=1S/C17H26N2O2/c1-4-21-17(20)19(15-9-10-18-11-15)12-14-7-5-6-8-16(14)13(2)3/h5-8,13,15,18H,4,9-12H2,1-3H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	764	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262729 (Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-carbamic a...) Show SMILES CC(C)OC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O2/c1-16(2)25-21(24)23(19-12-13-22-14-19)15-18-10-6-7-11-20(18)17-8-4-3-5-9-17/h3-11,16,19,22H,12-15H2,1-2H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	787	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262726 (CHEMBL449235 | N-Biphenyl-2-ylmethyl-N-(S)-pyrroli...) Show SMILES O=CN(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C18H20N2O/c21-14-20(17-10-11-19-12-17)13-16-8-4-5-9-18(16)15-6-2-1-3-7-15/h1-9,14,17,19H,10-13H2/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	869	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50262415 ((S)-N-(biphenyl-2-ylmethyl)-N-(pyrrolidin-3-yl)iso...) Show SMILES CC(C)C(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 |r| Show InChI InChI=1S/C21H26N2O/c1-16(2)21(24)23(19-12-13-22-14-19)15-18-10-6-7-11-20(18)17-8-4-3-5-9-17/h3-11,16,19,22H,12-15H2,1-2H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram uptake at human 5HTT expressed in HEK293 cells by SPA				Bioorg Med Chem Lett 18: 4355-9 (2008) Article DOI: 10.1016/j.bmcl.2008.06.071 BindingDB Entry DOI: 10.7270/Q2GH9HRM
					More data for this Ligand-Target Pair

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