Compile Data Set for Download or QSAR

Found 33 hits Enz. Inhib. hit(s) with all data for entry = 50035833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012990 (6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinol...) Show SMILES CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(20)18(21)17(12)13/h3-7,14,20-21H,2,8-10H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012990 (6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinol...) Show SMILES CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(20)18(21)17(12)13/h3-7,14,20-21H,2,8-10H2,1H3/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012991 (6-Cyclopropylmethyl-5,6,6a,7-tetrahydro-4H-dibenzo...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C20H21NO2/c22-17-7-6-14-10-16-18-13(8-9-21(16)11-12-4-5-12)2-1-3-15(18)19(14)20(17)23/h1-3,6-7,12,16,22-23H,4-5,8-11H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012989 (5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,1...) Show SMILES Oc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C16H15NO2/c18-13-5-4-10-8-12-14-9(6-7-17-12)2-1-3-11(14)15(10)16(13)19/h1-5,12,17-19H,6-8H2/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012987 (6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrahydro-4H-dibenzo...) Show SMILES OCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO3/c20-9-8-19-7-6-11-2-1-3-13-16(11)14(19)10-12-4-5-15(21)18(22)17(12)13/h1-5,14,20-22H,6-10H2/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012991 (6-Cyclopropylmethyl-5,6,6a,7-tetrahydro-4H-dibenzo...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C20H21NO2/c22-17-7-6-14-10-16-18-13(8-9-21(16)11-12-4-5-12)2-1-3-15(18)19(14)20(17)23/h1-3,6-7,12,16,22-23H,4-5,8-11H2/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012990 (6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinol...) Show SMILES CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(20)18(21)17(12)13/h3-7,14,20-21H,2,8-10H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012992 (6-Isopropyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CC(C)N1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C19H21NO2/c1-11(2)20-9-8-12-4-3-5-14-17(12)15(20)10-13-6-7-16(21)19(22)18(13)14/h3-7,11,15,21-22H,8-10H2,1-2H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	199	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM50012994 (6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quino...) Show SMILES CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012993 (6-Isobutyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES CC(C)CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C20H23NO2/c1-12(2)11-21-9-8-13-4-3-5-15-18(13)16(21)10-14-6-7-17(22)20(23)19(14)15/h3-7,12,16,22-23H,8-11H2,1-2H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	365	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012989 (5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,1...) Show SMILES Oc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C16H15NO2/c18-13-5-4-10-8-12-14-9(6-7-17-12)2-1-3-11(14)15(10)16(13)19/h1-5,12,17-19H,6-8H2/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012993 (6-Isobutyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES CC(C)CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C20H23NO2/c1-12(2)11-21-9-8-13-4-3-5-15-18(13)16(21)10-14-6-7-17(22)20(23)19(14)15/h3-7,12,16,22-23H,8-11H2,1-2H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007423 ((R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	615	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012991 (6-Cyclopropylmethyl-5,6,6a,7-tetrahydro-4H-dibenzo...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C20H21NO2/c22-17-7-6-14-10-16-18-13(8-9-21(16)11-12-4-5-12)2-1-3-15(18)19(14)20(17)23/h1-3,6-7,12,16,22-23H,4-5,8-11H2/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012992 (6-Isopropyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CC(C)N1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C19H21NO2/c1-11(2)20-9-8-12-4-3-5-14-17(12)15(20)10-13-6-7-16(21)19(22)18(13)14/h3-7,11,15,21-22H,8-10H2,1-2H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	895	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012989 (5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,1...) Show SMILES Oc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C16H15NO2/c18-13-5-4-10-8-12-14-9(6-7-17-12)2-1-3-11(14)15(10)16(13)19/h1-5,12,17-19H,6-8H2/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012987 (6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrahydro-4H-dibenzo...) Show SMILES OCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO3/c20-9-8-19-7-6-11-2-1-3-13-16(11)14(19)10-12-4-5-15(21)18(22)17(12)13/h1-5,14,20-22H,6-10H2/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012987 (6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrahydro-4H-dibenzo...) Show SMILES OCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C18H19NO3/c20-9-8-19-7-6-11-2-1-3-13-16(11)14(19)10-12-4-5-15(21)18(22)17(12)13/h1-5,14,20-22H,6-10H2/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012993 (6-Isobutyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qui...) Show SMILES CC(C)CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C20H23NO2/c1-12(2)11-21-9-8-13-4-3-5-15-18(13)16(21)10-14-6-7-17(22)20(23)19(14)15/h3-7,12,16,22-23H,8-11H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012992 (6-Isopropyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CC(C)N1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI InChI=1S/C19H21NO2/c1-11(2)20-9-8-12-4-3-5-14-17(12)15(20)10-13-6-7-16(21)19(22)18(13)14/h3-7,11,15,21-22H,8-10H2,1-2H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012988 (6-(2,2,3,3,3-Pentafluoro-propyl)-5,6,6a,7-tetrahyd...) Show SMILES Oc1ccc2C[C@H]3N(CC(F)(F)C(F)(F)F)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H16F5NO2/c20-18(21,19(22,23)24)9-25-7-6-10-2-1-3-12-15(10)13(25)8-11-4-5-14(26)17(27)16(11)12/h1-5,13,26-27H,6-9H2/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012995 (6-(2,2,2-Trifluoro-ethyl)-5,6,6a,7-tetrahydro-4H-d...) Show SMILES Oc1ccc2C[C@H]3N(CC(F)(F)F)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C18H16F3NO2/c19-18(20,21)9-22-7-6-10-2-1-3-12-15(10)13(22)8-11-4-5-14(23)17(24)16(11)12/h1-5,13,23-24H,6-9H2/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D1 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012995 (6-(2,2,2-Trifluoro-ethyl)-5,6,6a,7-tetrahydro-4H-d...) Show SMILES Oc1ccc2C[C@H]3N(CC(F)(F)F)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C18H16F3NO2/c19-18(20,21)9-22-7-6-10-2-1-3-12-15(10)13(22)8-11-4-5-14(23)17(24)16(11)12/h1-5,13,23-24H,6-9H2/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012988 (6-(2,2,3,3,3-Pentafluoro-propyl)-5,6,6a,7-tetrahyd...) Show SMILES Oc1ccc2C[C@H]3N(CC(F)(F)C(F)(F)F)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H16F5NO2/c20-18(21,19(22,23)24)9-25-7-6-10-2-1-3-12-15(10)13(25)8-11-4-5-14(26)17(27)16(11)12/h1-5,13,26-27H,6-9H2/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50012995 (6-(2,2,2-Trifluoro-ethyl)-5,6,6a,7-tetrahydro-4H-d...) Show SMILES Oc1ccc2C[C@H]3N(CC(F)(F)F)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C18H16F3NO2/c19-18(20,21)9-22-7-6-10-2-1-3-12-15(10)13(22)8-11-4-5-14(23)17(24)16(11)12/h1-5,13,23-24H,6-9H2/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Agonist activity was tested in vitro against Dopamine receptor from rat brain membranes with [3H]ADT-6,7-dihydroxy-2-aminotetralin]				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50012988 (6-(2,2,3,3,3-Pentafluoro-propyl)-5,6,6a,7-tetrahyd...) Show SMILES Oc1ccc2C[C@H]3N(CC(F)(F)C(F)(F)F)CCc4cccc(c34)-c2c1O Show InChI InChI=1S/C19H16F5NO2/c20-18(21,19(22,23)24)9-25-7-6-10-2-1-3-12-15(10)13(25)8-11-4-5-14(26)17(27)16(11)12/h1-5,13,26-27H,6-9H2/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Dopamine receptor D2 affinity was tested in vitro against corpus striatum from rat brain membranes				J Med Chem 33: 39-44 (1990) BindingDB Entry DOI: 10.7270/Q2183732
					More data for this Ligand-Target Pair