Compile Data Set for Download or QSAR

Found 134 hits of ec50 for UniProtKB: P35439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583031 (CHEMBL5081078) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Br)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM18133 (2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...) Show SMILES NCC(O)=O Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	91	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583019 (CHEMBL5081008) Show SMILES CCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM23167 ((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...) Show SMILES N[C@H](CO)C(O)=O Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583021 (CHEMBL5091289) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2ccccc12)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583022 (CHEMBL5085583) Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583023 (CHEMBL5081203) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Cl)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238352 (CHEMBL4061206) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C28H30BrNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436093 (CHEMBL2397268) Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C31H28BrNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238357 (CHEMBL4100452) Show SMILES CC(C)Oc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C30H32F3NO3S/c1-19(2)36-25-10-8-24(9-11-25)35-18-28-27-13-12-26(37-20(3)4)17-21(27)14-15-34(28)29(38)22-6-5-7-23(16-22)30(31,32)33/h5-13,16-17,19-20,28H,14-15,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436094 (CHEMBL2397267) Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C31H28ClNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238355 (CHEMBL4091770) Show SMILES CC(C)Oc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C29H32ClNO3S/c1-19(2)33-25-10-8-24(9-11-25)32-18-28-27-13-12-26(34-20(3)4)17-21(27)14-15-31(28)29(35)22-6-5-7-23(30)16-22/h5-13,16-17,19-20,28H,14-15,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238350 (CHEMBL4063861) Show SMILES COc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C27H28ClNO3S/c1-18(2)32-24-11-12-25-19(16-24)13-14-29(27(33)20-5-4-6-21(28)15-20)26(25)17-31-23-9-7-22(30-3)8-10-23/h4-12,15-16,18,26H,13-14,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238354 (CHEMBL4070902) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2ccc(F)c(Cl)c2)cc1 Show InChI InChI=1S/C28H29ClFNO3S/c1-4-32-21-6-8-22(9-7-21)33-17-27-24-11-10-23(34-18(2)3)15-19(24)13-14-31(27)28(35)20-5-12-26(30)25(29)16-20/h5-12,15-16,18,27H,4,13-14,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238363 (CHEMBL4099510) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C29H30F3NO3S/c1-4-34-23-8-10-24(11-9-23)35-18-27-26-13-12-25(36-19(2)3)17-20(26)14-15-33(27)28(37)21-6-5-7-22(16-21)29(30,31)32/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238364 (CHEMBL4064008) Show SMILES COc1ccc(OC[C@H]2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C27H28ClNO3S/c1-18(2)32-24-11-12-25-19(16-24)13-14-29(27(33)20-5-4-6-21(28)15-20)26(25)17-31-23-9-7-22(30-3)8-10-23/h4-12,15-16,18,26H,13-14,17H2,1-3H3/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545698 (CHEMBL4637429) Show SMILES COc1ccc(OCC2N(Cc3cccc(Cl)c3)C(=O)Cc3cc(OC(C)C)ccc23)cc1 Show InChI InChI=1S/C27H28ClNO4/c1-18(2)33-24-11-12-25-20(14-24)15-27(30)29(16-19-5-4-6-21(28)13-19)26(25)17-32-23-9-7-22(31-3)8-10-23/h4-14,18,26H,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	501	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238335 (CHEMBL4083076) Show SMILES CCOc1ccc(OC[C@H]2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(F)c2)cc1 |r| Show InChI InChI=1S/C28H30FNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545700 (CHEMBL4633060) Show SMILES COc1ccc(OCC2N(Cc3cccc(c3)C(F)(F)F)C(=O)Cc3cc(OC(C)C)ccc23)cc1 Show InChI InChI=1S/C28H28F3NO4/c1-18(2)36-24-11-12-25-20(14-24)15-27(33)32(16-19-5-4-6-21(13-19)28(29,30)31)26(25)17-35-23-9-7-22(34-3)8-10-23/h4-14,18,26H,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545699 (CHEMBL4636021) Show SMILES COc1ccc(OCC2N(Cc3cccc(Cl)c3)C(=O)Cc3cc(OCC(C)C)ccc23)cc1 Show InChI InChI=1S/C28H30ClNO4/c1-19(2)17-33-25-11-12-26-21(14-25)15-28(31)30(16-20-5-4-6-22(29)13-20)27(26)18-34-24-9-7-23(32-3)8-10-24/h4-14,19,27H,15-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545716 (CHEMBL4636029) Show SMILES COc1ccc(OC[C@@H]2N(Cc3cccc(c3)C(F)(F)F)C(=O)Cn3cccc23)cc1 |r| Show InChI InChI=1S/C23H21F3N2O3/c1-30-18-7-9-19(10-8-18)31-15-21-20-6-3-11-27(20)14-22(29)28(21)13-16-4-2-5-17(12-16)23(24,25)26/h2-12,21H,13-15H2,1H3/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436088 (CHEMBL2397121) Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C26H24ClNO3/c1-30-22-9-6-18(7-10-22)8-13-25-24-12-11-23(31-2)17-19(24)14-15-28(25)26(29)20-4-3-5-21(27)16-20/h3-13,16-17,25H,14-15H2,1-2H3/b13-8+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436102 (CHEMBL2397256 | US10273214, Example 1180-26) Show SMILES COc1ccc(OCC2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H24ClNO4/c1-29-20-6-8-21(9-7-20)31-16-24-23-11-10-22(30-2)15-17(23)12-13-27(24)25(28)18-4-3-5-19(26)14-18/h3-11,14-15,24H,12-13,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436102 (CHEMBL2397256 | US10273214, Example 1180-26) Show SMILES COc1ccc(OCC2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H24ClNO4/c1-29-20-6-8-21(9-7-20)31-16-24-23-11-10-22(30-2)15-17(23)12-13-27(24)25(28)18-4-3-5-19(26)14-18/h3-11,14-15,24H,12-13,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238359 (CHEMBL4091772) Show SMILES COc1ccc(OC[C@@H]2N(CCc3cc(OC(C)C)ccc23)C(=O)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C27H28ClNO4/c1-18(2)33-24-11-12-25-19(16-24)13-14-29(27(30)20-5-4-6-21(28)15-20)26(25)17-32-23-9-7-22(31-3)8-10-23/h4-12,15-16,18,26H,13-14,17H2,1-3H3/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436102 (CHEMBL2397256 | US10273214, Example 1180-26) Show SMILES COc1ccc(OCC2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H24ClNO4/c1-29-20-6-8-21(9-7-20)31-16-24-23-11-10-22(30-2)15-17(23)12-13-27(24)25(28)18-4-3-5-19(26)14-18/h3-11,14-15,24H,12-13,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238351 (CHEMBL4091645) Show SMILES COc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(F)c2)cc1 Show InChI InChI=1S/C27H28FNO3S/c1-18(2)32-24-11-12-25-19(16-24)13-14-29(27(33)20-5-4-6-21(28)15-20)26(25)17-31-23-9-7-22(30-3)8-10-23/h4-12,15-16,18,26H,13-14,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436098 (CHEMBL2397262) Show SMILES COc1ccc(OCC2N(CCc3cc(C)c(C)cc23)C(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C26H26BrNO3/c1-17-13-19-11-12-28(26(29)20-5-4-6-21(27)15-20)25(24(19)14-18(17)2)16-31-23-9-7-22(30-3)8-10-23/h4-10,13-15,25H,11-12,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238353 (CHEMBL4081483) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(F)c2)cc1 Show InChI InChI=1S/C28H30FNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238356 (CHEMBL4062279) Show SMILES CC(C)Oc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(F)c2)cc1 Show InChI InChI=1S/C29H32FNO3S/c1-19(2)33-25-10-8-24(9-11-25)32-18-28-27-13-12-26(34-20(3)4)17-21(27)14-15-31(28)29(35)22-6-5-7-23(30)16-22/h5-13,16-17,19-20,28H,14-15,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238338 (CHEMBL4068612) Show SMILES COc1ccc(OCC2N(CCc3cc(OCC(C)C)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H30ClNO4/c1-19(2)17-33-25-11-12-26-20(16-25)13-14-30(28(31)21-5-4-6-22(29)15-21)27(26)18-34-24-9-7-23(32-3)8-10-24/h4-12,15-16,19,27H,13-14,17-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545718 (CHEMBL4638424) Show SMILES COc1ccc(OC[C@@H]2N(CCn3cccc23)C(=O)c2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C23H21F3N2O3/c1-30-18-7-9-19(10-8-18)31-15-21-20-6-3-11-27(20)12-13-28(21)22(29)16-4-2-5-17(14-16)23(24,25)26/h2-11,14,21H,12-13,15H2,1H3/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436090 (CHEMBL2397119 | US10273214, Example 1180-31) Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C27H26ClNO4/c1-31-22-10-7-18(8-11-22)9-12-24-23-17-26(33-3)25(32-2)16-19(23)13-14-29(24)27(30)20-5-4-6-21(28)15-20/h4-12,15-17,24H,13-14H2,1-3H3/b12-9+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238338 (CHEMBL4068612) Show SMILES COc1ccc(OCC2N(CCc3cc(OCC(C)C)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H30ClNO4/c1-19(2)17-33-25-11-12-26-20(16-25)13-14-30(28(31)21-5-4-6-22(29)15-21)27(26)18-34-24-9-7-23(32-3)8-10-24/h4-12,15-16,19,27H,13-14,17-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436099 (CHEMBL2397261) Show SMILES COc1ccc(OCC2N(CCc3cc(C)c(C)cc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C26H26ClNO3/c1-17-13-19-11-12-28(26(29)20-5-4-6-21(27)15-20)25(24(19)14-18(17)2)16-31-23-9-7-22(30-3)8-10-23/h4-10,13-15,25H,11-12,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50237806 (CHEMBL4099073) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OCC(C)C)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C29H32ClNO4/c1-4-33-24-8-10-25(11-9-24)35-19-28-27-13-12-26(34-18-20(2)3)17-21(27)14-15-31(28)29(32)22-6-5-7-23(30)16-22/h5-13,16-17,20,28H,4,14-15,18-19H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545714 (CHEMBL4641889) Show SMILES COc1ccc(OCC2N(Cc3cccc(c3)C(F)(F)F)C(=O)Cn3cccc23)cc1 Show InChI InChI=1S/C23H21F3N2O3/c1-30-18-7-9-19(10-8-18)31-15-21-20-6-3-11-27(20)14-22(29)28(21)13-16-4-2-5-17(12-16)23(24,25)26/h2-12,21H,13-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238341 (CHEMBL4064435) Show SMILES COc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=O)c2cccc(I)c2)cc1 Show InChI InChI=1S/C27H28INO4/c1-18(2)33-24-11-12-25-19(16-24)13-14-29(27(30)20-5-4-6-21(28)15-20)26(25)17-32-23-9-7-22(31-3)8-10-23/h4-12,15-16,18,26H,13-14,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238367 (CHEMBL4089357) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H30ClNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436087 (CHEMBL2397274) Show SMILES COc1ccc(\C=C\C2N(CCc3cc(OC)ccc23)C(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C26H24BrNO3/c1-30-22-9-6-18(7-10-22)8-13-25-24-12-11-23(31-2)17-19(24)14-15-28(25)26(29)20-4-3-5-21(27)16-20/h3-13,16-17,25H,14-15H2,1-2H3/b13-8+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238365 (CHEMBL4069391) Show SMILES CCC(CC)Oc1ccc2C(COc3ccc(OC)cc3)N(CCc2c1)C(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C29H32ClNO4/c1-4-23(5-2)35-26-13-14-27-20(18-26)15-16-31(29(32)21-7-6-8-22(30)17-21)28(27)19-34-25-11-9-24(33-3)10-12-25/h6-14,17-18,23,28H,4-5,15-16,19H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238347 (CHEMBL4064895) Show SMILES CC(C)Oc1ccc2C(COc3ccc(OC(F)(F)F)cc3)N(CCc2c1)C(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C27H25ClF3NO4/c1-17(2)35-23-10-11-24-18(15-23)12-13-32(26(33)19-4-3-5-20(28)14-19)25(24)16-34-21-6-8-22(9-7-21)36-27(29,30)31/h3-11,14-15,17,25H,12-13,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436077 (CHEMBL2397123) Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cc(Cl)cc(Cl)c2)cc1 Show InChI InChI=1S/C26H25Cl2NO5/c1-31-20-4-6-21(7-5-20)34-15-23-22-14-25(33-3)24(32-2)12-16(22)8-9-29(23)26(30)17-10-18(27)13-19(28)11-17/h4-7,10-14,23H,8-9,15H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238339 (CHEMBL4096621) Show SMILES COc1ccc(OCC2N(CCc3cc(OC4CCCCC4)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C30H32ClNO4/c1-34-24-10-12-25(13-11-24)35-20-29-28-15-14-27(36-26-8-3-2-4-9-26)19-21(28)16-17-32(29)30(33)22-6-5-7-23(31)18-22/h5-7,10-15,18-19,26,29H,2-4,8-9,16-17,20H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545713 (CHEMBL4639711) Show SMILES COc1ccc(OCC2N(CCn3cccc23)C(=O)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C23H21F3N2O3/c1-30-18-7-9-19(10-8-18)31-15-21-20-6-3-11-27(20)12-13-28(21)22(29)16-4-2-5-17(14-16)23(24,25)26/h2-11,14,21H,12-13,15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545701 (CHEMBL4648608) Show SMILES COc1ccc(OCC2N(Cc3cccc(F)c3)C(=O)Cc3cc(OC(C)C)ccc23)cc1 Show InChI InChI=1S/C27H28FNO4/c1-18(2)33-24-11-12-25-20(14-24)15-27(30)29(16-19-5-4-6-21(28)13-19)26(25)17-32-23-9-7-22(31-3)8-10-23/h4-14,18,26H,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50545717 (CHEMBL4637740) Show SMILES COc1ccc(OC[C@@H]2N(CCn3cccc23)C(=O)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C22H21ClN2O3/c1-27-18-7-9-19(10-8-18)28-15-21-20-6-3-11-24(20)12-13-25(21)22(26)16-4-2-5-17(23)14-16/h2-11,14,21H,12-13,15H2,1H3/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238360 (CHEMBL4101985) Show SMILES COc1ccc(OC[C@@H]2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C27H28ClNO3S/c1-18(2)32-24-11-12-25-19(16-24)13-14-29(27(33)20-5-4-6-21(28)15-20)26(25)17-31-23-9-7-22(30-3)8-10-23/h4-12,15-16,18,26H,13-14,17H2,1-3H3/t26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238332 (CHEMBL4100185) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=O)c2ccc(F)c(Cl)c2)cc1 Show InChI InChI=1S/C28H29ClFNO4/c1-4-33-21-6-8-22(9-7-21)34-17-27-24-11-10-23(35-18(2)3)15-19(24)13-14-31(27)28(32)20-5-12-26(30)25(29)16-20/h5-12,15-16,18,27H,4,13-14,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436082 (CHEMBL2397103 | US10273214, Example 1391) Show SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C26H26BrNO5/c1-30-20-7-9-21(10-8-20)33-16-23-22-15-25(32-3)24(31-2)14-17(22)11-12-28(23)26(29)18-5-4-6-19(27)13-18/h4-10,13-15,23H,11-12,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 134 total )  |  Next  |  Last  >>

Jump to: