Compile Data Set for Download or QSAR

Found 240 hits of ic50 for UniProtKB: P00749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264615 (US9718760, C182) Show SMILES CCCCCCCN(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C19H25NO8S2/c1-2-3-4-5-6-11-20(29(25,26)14-7-9-16(21)18(23)12-14)30(27,28)15-8-10-17(22)19(24)13-15/h7-10,12-13,21-24H,2-6,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264650 (US9718760, C204) Show SMILES Oc1ccc(cc1O)C(=O)OCC(CNS(=O)(=O)c1cccc(c1)C(F)(F)F)OC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C24H20F3NO10S/c25-24(26,27)15-2-1-3-17(10-15)39(35,36)28-11-16(38-23(34)14-5-7-19(30)21(32)9-14)12-37-22(33)13-4-6-18(29)20(31)8-13/h1-10,16,28-32H,11-12H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264630 (US9718760, C198) Show SMILES Oc1ccc(CCNS(=O)(=O)c2ccc(O)c(O)c2)cc1O Show InChI InChI=1S/C14H15NO6S/c16-11-3-1-9(7-13(11)18)5-6-15-22(20,21)10-2-4-12(17)14(19)8-10/h1-4,7-8,15-19H,5-6H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264611 (US9718760, C188) Show SMILES CCCCCCc1ccc(cc1)N(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C24H27NO8S2/c1-2-3-4-5-6-17-7-9-18(10-8-17)25(34(30,31)19-11-13-21(26)23(28)15-19)35(32,33)20-12-14-22(27)24(29)16-20/h7-16,26-29H,2-6H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264602 (US9718760, C197) Show SMILES Oc1ccc(CCN(S(=O)(=O)c2ccccc2)S(=O)(=O)c2ccc(O)c(O)c2)cc1O Show InChI InChI=1S/C20H19NO8S2/c22-17-8-6-14(12-19(17)24)10-11-21(30(26,27)15-4-2-1-3-5-15)31(28,29)16-7-9-18(23)20(25)13-16/h1-9,12-13,22-25H,10-11H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	173	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264616 (US9718760, C183) Show SMILES CCCCCCCCCN(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C21H29NO8S2/c1-2-3-4-5-6-7-8-13-22(31(27,28)16-9-11-18(23)20(25)14-16)32(29,30)17-10-12-19(24)21(26)15-17/h9-12,14-15,23-26H,2-8,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264613 (US9718760, C157) Show SMILES CCCCCCCCCCN(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H31NO8S2/c1-2-3-4-5-6-7-8-9-14-23(32(28,29)17-10-12-19(24)21(26)15-17)33(30,31)18-11-13-20(25)22(27)16-18/h10-13,15-16,24-27H,2-9,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264609 (US9718760, C163) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N(c1cccc(c1)C(F)(F)F)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C19H14F3NO8S2/c20-19(21,22)11-2-1-3-12(8-11)23(32(28,29)13-4-6-15(24)17(26)9-13)33(30,31)14-5-7-16(25)18(27)10-14/h1-10,24-27H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	288	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264610 (US9718760, C165) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N(c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C24H19NO8S2/c26-21-12-10-19(14-23(21)28)34(30,31)25(35(32,33)20-11-13-22(27)24(29)15-20)18-8-6-17(7-9-18)16-4-2-1-3-5-16/h1-15,26-29H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264645 (US9718760, C185) Show SMILES CCCCCCCCCN(CCN(CCCCCCCCC)S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C32H52N2O8S2/c1-3-5-7-9-11-13-15-21-33(43(39,40)27-17-19-29(35)31(37)25-27)23-24-34(22-16-14-12-10-8-6-4-2)44(41,42)28-18-20-30(36)32(38)26-28/h17-20,25-26,35-38H,3-16,21-24H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264646 (US9718760, C196) Show SMILES CCCCCCCCCCN(CCN(C)S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C25H38N2O8S2/c1-3-4-5-6-7-8-9-10-15-27(37(34,35)21-12-14-23(29)25(31)19-21)17-16-26(2)36(32,33)20-11-13-22(28)24(30)18-20/h11-14,18-19,28-31H,3-10,15-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264644 (US9718760, C184) Show SMILES CCCCCCCN(CCN(CCCCCCC)S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C28H44N2O8S2/c1-3-5-7-9-11-17-29(39(35,36)23-13-15-25(31)27(33)21-23)19-20-30(18-12-10-8-6-4-2)40(37,38)24-14-16-26(32)28(34)22-24/h13-16,21-22,31-34H,3-12,17-20H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	590	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264643 (US9718760, C176) Show SMILES CCCCCCCCN(CCN(CCCCCCCC)S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C30H48N2O8S2/c1-3-5-7-9-11-13-19-31(41(37,38)25-15-17-27(33)29(35)23-25)21-22-32(20-14-12-10-8-6-4-2)42(39,40)26-16-18-28(34)30(36)24-26/h15-18,23-24,33-36H,3-14,19-22H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264607 (US9718760, C153) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N(c1ccccc1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H15NO8S2/c20-15-8-6-13(10-17(15)22)28(24,25)19(12-4-2-1-3-5-12)29(26,27)14-7-9-16(21)18(23)11-14/h1-11,20-23H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	700	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264628 (US9718760, C187) Show SMILES CCCCCCc1ccc(NS(=O)(=O)c2ccc(O)c(O)c2)cc1 Show InChI InChI=1S/C18H23NO4S/c1-2-3-4-5-6-14-7-9-15(10-8-14)19-24(22,23)16-11-12-17(20)18(21)13-16/h7-13,19-21H,2-6H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	910	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264612 (US9718760, C195) Show SMILES CCCCCCCCCCCCc1ccc(cc1)N(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C30H39NO8S2/c1-2-3-4-5-6-7-8-9-10-11-12-23-13-15-24(16-14-23)31(40(36,37)25-17-19-27(32)29(34)21-25)41(38,39)26-18-20-28(33)30(35)22-26/h13-22,32-35H,2-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	920	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264601 (US9718760, C191) Show SMILES CCCCCCCCN(S(=O)(=O)c1ccc(CCCCC)cc1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C25H37NO6S2/c1-3-5-7-8-9-11-19-26(34(31,32)23-17-18-24(27)25(28)20-23)33(29,30)22-15-13-21(14-16-22)12-10-6-4-2/h13-18,20,27-28H,3-12,19H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264623 (US9718760, C180) Show SMILES CCCCCCCCN(CCCCCC)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C20H35NO4S/c1-3-5-7-9-10-12-16-21(15-11-8-6-4-2)26(24,25)18-13-14-19(22)20(23)17-18/h13-14,17,22-23H,3-12,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264597 (US9718760, C152) Show SMILES CCCCCCCCN(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1cc(F)c(O)c(F)c1 Show InChI InChI=1S/C20H25F2NO7S2/c1-2-3-4-5-6-7-10-23(31(27,28)14-8-9-18(24)19(25)13-14)32(29,30)15-11-16(21)20(26)17(22)12-15/h8-9,11-13,24-26H,2-7,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264618 (US9718760, C171) Show SMILES CCCCCCN(CCCCCC)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H31NO4S/c1-3-5-7-9-13-19(14-10-8-6-4-2)24(22,23)16-11-12-17(20)18(21)15-16/h11-12,15,20-21H,3-10,13-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264635 (US9718760, C271) Show SMILES OC(=O)CCCCCNS(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C12H17NO6S/c14-10-6-5-9(8-11(10)15)20(18,19)13-7-3-1-2-4-12(16)17/h5-6,8,13-15H,1-4,7H2,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264619 (US9718760, C172) Show SMILES CCCCCCCCN(Cc1cc(Cl)c(O)c(Cl)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C21H27Cl2NO5S/c1-2-3-4-5-6-7-10-24(14-15-11-17(22)21(27)18(23)12-15)30(28,29)16-8-9-19(25)20(26)13-16/h8-9,11-13,25-27H,2-7,10,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264642 (US9718760, C168) Show SMILES CCCCCCCCCCN(CCN(CCCCCCCCCC)S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C34H56N2O8S2/c1-3-5-7-9-11-13-15-17-23-35(45(41,42)29-19-21-31(37)33(39)27-29)25-26-36(24-18-16-14-12-10-8-6-4-2)46(43,44)30-20-22-32(38)34(40)28-30/h19-22,27-28,37-40H,3-18,23-26H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264600 (US9718760, C189) Show SMILES CCCCCCc1ccc(cc1)N(S(=O)(=O)c1ccc(CCC)cc1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C27H33NO6S2/c1-3-5-6-7-9-22-10-14-23(15-11-22)28(36(33,34)25-18-19-26(29)27(30)20-25)35(31,32)24-16-12-21(8-4-2)13-17-24/h10-20,29-30H,3-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264622 (US9718760, C179) Show SMILES CCCCCCCCN(Cc1cccc(c1)C(F)(F)F)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H28F3NO4S/c1-2-3-4-5-6-7-13-26(16-17-9-8-10-18(14-17)22(23,24)25)31(29,30)19-11-12-20(27)21(28)15-19/h8-12,14-15,27-28H,2-7,13,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264614 (US9718760, C158) Show SMILES CCCCCCCCCCCCN(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C24H35NO8S2/c1-2-3-4-5-6-7-8-9-10-11-16-25(34(30,31)19-12-14-21(26)23(28)17-19)35(32,33)20-13-15-22(27)24(29)18-20/h12-15,17-18,26-29H,2-11,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264648 (US9718760, C161) Show SMILES CCCCCCCCNC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C15H23NO4/c1-2-3-4-5-6-7-8-16-15(20)11-9-12(17)14(19)13(18)10-11/h9-10,17-19H,2-8H2,1H3,(H,16,20)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264608 (US9718760, C162) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N(CCc1ccccn1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C19H18N2O8S2/c22-16-6-4-14(11-18(16)24)30(26,27)21(10-8-13-3-1-2-9-20-13)31(28,29)15-5-7-17(23)19(25)12-15/h1-7,9,11-12,22-25H,8,10H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264603 (US9718760, C224) Show SMILES CCCCCCCCN(S(=O)(=O)c1ccc(O)cc1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C20H27NO7S2/c1-2-3-4-5-6-7-14-21(29(25,26)17-10-8-16(22)9-11-17)30(27,28)18-12-13-19(23)20(24)15-18/h8-13,15,22-24H,2-7,14H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264660 (US9718760, C206) Show SMILES Oc1ccc(\C=C2/SC(=O)N(Cc3cccc(Br)c3)C2=O)cc1O Show InChI InChI=1S/C17H12BrNO4S/c18-12-3-1-2-11(6-12)9-19-16(22)15(24-17(19)23)8-10-4-5-13(20)14(21)7-10/h1-8,20-21H,9H2/b15-8-	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.96E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264626 (US9718760, C205) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N1CCc2ccccc12 Show InChI InChI=1S/C14H13NO4S/c16-13-6-5-11(9-14(13)17)20(18,19)15-8-7-10-3-1-2-4-12(10)15/h1-6,9,16-17H,7-8H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.05E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264621 (US9718760, C177) Show SMILES CCCCCCCCN(Cc1cccc(Cl)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C21H28ClNO4S/c1-2-3-4-5-6-7-13-23(16-17-9-8-10-18(22)14-17)28(26,27)19-11-12-20(24)21(25)15-19/h8-12,14-15,24-25H,2-7,13,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.11E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264658 (US9718760, C199) Show SMILES Oc1ccc(\C=C2/SC(=O)N(Cc3ccccc3)C2=O)cc1O Show InChI InChI=1S/C17H13NO4S/c19-13-7-6-12(8-14(13)20)9-15-16(21)18(17(22)23-15)10-11-4-2-1-3-5-11/h1-9,19-20H,10H2/b15-9-	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.36E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264617 (US9718760, C170) Show SMILES CCCCCCCCN(CCCCCCCC)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H39NO4S/c1-3-5-7-9-11-13-17-23(18-14-12-10-8-6-4-2)28(26,27)20-15-16-21(24)22(25)19-20/h15-16,19,24-25H,3-14,17-18H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.49E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264620 (US9718760, C175) Show SMILES CCCCCCCCN(CC(O)c1ccccc1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H31NO5S/c1-2-3-4-5-6-10-15-23(17-22(26)18-11-8-7-9-12-18)29(27,28)19-13-14-20(24)21(25)16-19/h7-9,11-14,16,22,24-26H,2-6,10,15,17H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.74E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264624 (US9718760, C186) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N1CCC[C@H]1CCc1ccccc1 |r| Show InChI InChI=1S/C18H21NO4S/c20-17-11-10-16(13-18(17)21)24(22,23)19-12-4-7-15(19)9-8-14-5-2-1-3-6-14/h1-3,5-6,10-11,13,15,20-21H,4,7-9,12H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.98E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264629 (US9718760, C190) Show SMILES Oc1ccc(cc1O)S(=O)(=O)Nc1ccc(cc1)-c1cccc(F)c1 Show InChI InChI=1S/C18H14FNO4S/c19-14-3-1-2-13(10-14)12-4-6-15(7-5-12)20-25(23,24)16-8-9-17(21)18(22)11-16/h1-11,20-22H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264640 (US9718760, C303) Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCc1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C14H11ClF3NO4S/c15-11-3-1-8(5-10(11)14(16,17)18)7-19-24(22,23)9-2-4-12(20)13(21)6-9/h1-6,19-21H,7H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264631 (US9718760, C232) Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCCCc1ccccc1 Show InChI InChI=1S/C15H17NO4S/c17-14-9-8-13(11-15(14)18)21(19,20)16-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,16-18H,4,7,10H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264664 (US9718760, C228) Show SMILES Oc1ccc(cc1O)-c1nc(cs1)-c1ccc2NC(=O)Cc2c1 Show InChI InChI=1S/C17H12N2O3S/c20-14-4-2-10(6-15(14)21)17-19-13(8-23-17)9-1-3-12-11(5-9)7-16(22)18-12/h1-6,8,20-21H,7H2,(H,18,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264636 (US9718760, C272) Show SMILES OC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C15H15NO6S/c17-13-7-6-11(9-14(13)18)23(21,22)16-12(15(19)20)8-10-4-2-1-3-5-10/h1-7,9,12,16-18H,8H2,(H,19,20)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264661 (US9718760, C207) Show SMILES Oc1ccc(\C=C2/SC(=O)N(Cc3cccc(c3)-c3ccc(OC(F)(F)F)cc3)C2=O)cc1O Show InChI InChI=1S/C24H16F3NO5S/c25-24(26,27)33-18-7-5-16(6-8-18)17-3-1-2-15(10-17)13-28-22(31)21(34-23(28)32)12-14-4-9-19(29)20(30)11-14/h1-12,29-30H,13H2/b21-12-	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264659 (US9718760, C203) Show SMILES Oc1ccc(\C=C2/SC(=O)N(Cc3ccc(Br)cc3)C2=O)cc1O Show InChI InChI=1S/C17H12BrNO4S/c18-12-4-1-10(2-5-12)9-19-16(22)15(24-17(19)23)8-11-3-6-13(20)14(21)7-11/h1-8,20-21H,9H2/b15-8-	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264599 (US9718760, C173) Show SMILES CCCCCCCCN(S(=O)(=O)c1ccc(cc1)-c1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C27H30F3NO7S2/c1-2-3-4-5-6-7-18-31(40(36,37)24-16-17-25(32)26(33)19-24)39(34,35)23-14-10-21(11-15-23)20-8-12-22(13-9-20)38-27(28,29)30/h8-17,19,32-33H,2-7,18H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264634 (US9718760, C270) Show SMILES NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C15H16N2O5S/c16-15(20)12(8-10-4-2-1-3-5-10)17-23(21,22)11-6-7-13(18)14(19)9-11/h1-7,9,12,17-19H,8H2,(H2,16,20)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.95E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264598 (US9718760, C155) Show SMILES CCCCCCCCN(S(=O)(=O)c1cc(F)c(O)c(F)c1)S(=O)(=O)c1cc(F)c(O)c(F)c1 Show InChI InChI=1S/C20H23F4NO6S2/c1-2-3-4-5-6-7-8-25(32(28,29)13-9-15(21)19(26)16(22)10-13)33(30,31)14-11-17(23)20(27)18(24)12-14/h9-12,26-27H,2-8H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.04E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264639 (US9718760, C275) Show SMILES OC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C15H15NO6S/c17-13-7-6-11(9-14(13)18)23(21,22)16-12(15(19)20)8-10-4-2-1-3-5-10/h1-7,9,12,16-18H,8H2,(H,19,20)/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.05E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264604 (US9718760, C292) Show SMILES CCCCCCCCN(S(=O)(=O)c1cccc(O)c1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C20H27NO7S2/c1-2-3-4-5-6-7-13-21(29(25,26)17-10-8-9-16(22)14-17)30(27,28)18-11-12-19(23)20(24)15-18/h8-12,14-15,22-24H,2-7,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.65E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264627 (US9718760, C160) Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C13H13NO4S/c15-12-7-6-11(8-13(12)16)19(17,18)14-9-10-4-2-1-3-5-10/h1-8,14-16H,9H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM264637 (US9718760, C273) Show SMILES OC(=O)[C@@H](NS(=O)(=O)c1ccc(O)c(O)c1)c1ccccc1 |r| Show InChI InChI=1S/C14H13NO6S/c16-11-7-6-10(8-12(11)17)22(20,21)15-13(14(18)19)9-4-2-1-3-5-9/h1-8,13,15-17H,(H,18,19)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.56E+4	n/a	n/a	n/a	n/a	7.4	25
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...				US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK
					More data for this Ligand-Target Pair

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