BindingDB PrimarySearch

Found 15 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM82505'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									FASEB J 10: 1398-407 (1996) Article DOI: 10.1096/fasebj.10.12.8903510 BindingDB Entry DOI: 10.7270/Q2TQ602G
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article	0.0129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for binding affinity against 5-HT4 receptor in guinea pig striata using [3H]GR-113808 as radioligand				Citation and Details Article DOI: 10.1016/S0960-894X(01)80414-5 BindingDB Entry DOI: 10.7270/Q2X63QND
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP K_i Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
Janssen Research Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Sus scrofa)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article	0.126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was evaluated for its ability to inhibit the binding of 5-HT4 receptor radioligand [125I]SB 207710 to piglet hippocampal membrane				Citation and Details Article DOI: 10.1016/S0960-894X(01)80176-1 BindingDB Entry DOI: 10.7270/Q25T3MSB
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (RAT)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (RAT)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (RAT)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.0794	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...				Citation and Details Article DOI: 10.1016/S0960-894X(01)80176-1 BindingDB Entry DOI: 10.7270/Q25T3MSB
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMP				J Med Chem 38: 4760-3 (1996) BindingDB Entry DOI: 10.7270/Q2B56M1M
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 5-HT-evoked 5-HT4 receptor-mediated contractions in the guinea pig distal colon longitudinal muscle myenteric plexus (LMMP)				J Med Chem 36: 4121-3 (1994) BindingDB Entry DOI: 10.7270/Q20003D7
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM82505 (CAS_121881 \| NSC_121881 \| SB204070) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a
Molecular NeuroImaging LLC Curated by ChEMBL					Assay Description Binding affinity to 5HT4 receptor in guinea pig distal colon				Bioorg Med Chem Lett 23: 6243-7 (2013) Article DOI: 10.1016/j.bmcl.2013.09.097 BindingDB Entry DOI: 10.7270/Q2RJ4KZ2
Molecular NeuroImaging LLC Curated by ChEMBL					More data for this Ligand-Target Pair