BindingDB PrimarySearch

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinase suppressor of Ras 2' and Ligand = 'BDBM50095227'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kinase suppressor of Ras 2 (Human)	BDBM50095227 ((6,7-Dimethoxy-quinazolin-4-yl)-(4-phenoxy-phenyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	602	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai US Patent					Assay Description The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...				US Patent US10548897 (2020) BindingDB Entry DOI: 10.7270/Q25H7JMP
Icahn School of Medicine at Mount Sinai US Patent					More data for this Ligand-Target Pair