Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM16307'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM16307 (2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...) Show SMILES NC(=N)c1ccc2nc(Cc3ccccn3)[nH]c2c1 Show InChI InChI=1S/C14H13N5/c15-14(16)9-4-5-11-12(7-9)19-13(18-11)8-10-3-1-2-6-17-10/h1-7H,8H2,(H3,15,16)(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+4	-28.1	n/a	n/a	n/a	n/a	n/a	8.2	22
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM16307 (2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...) Show SMILES NC(=N)c1ccc2nc(Cc3ccccn3)[nH]c2c1 Show InChI InChI=1S/C14H13N5/c15-14(16)9-4-5-11-12(7-9)19-13(18-11)8-10-3-1-2-6-17-10/h1-7H,8H2,(H3,15,16)(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Binding affinity to thrombin in presence of Zn2+				Bioorg Med Chem Lett 16: 710-3 (2005) Article DOI: 10.1016/j.bmcl.2005.10.023 BindingDB Entry DOI: 10.7270/Q2VM4BSJ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM16307 (2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...) Show SMILES NC(=N)c1ccc2nc(Cc3ccccn3)[nH]c2c1 Show InChI InChI=1S/C14H13N5/c15-14(16)9-4-5-11-12(7-9)19-13(18-11)8-10-3-1-2-6-17-10/h1-7H,8H2,(H3,15,16)(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Curated by ChEMBL					Assay Description Binding affinity to thrombin in absence of Zn2+				Bioorg Med Chem Lett 16: 710-3 (2005) Article DOI: 10.1016/j.bmcl.2005.10.023 BindingDB Entry DOI: 10.7270/Q2VM4BSJ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM16307 (2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...) Show SMILES NC(=N)c1ccc2nc(Cc3ccccn3)[nH]c2c1 Show InChI InChI=1S/C14H13N5/c15-14(16)9-4-5-11-12(7-9)19-13(18-11)8-10-3-1-2-6-17-10/h1-7H,8H2,(H3,15,16)(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arris					Assay Description Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...				Nature 391: 608-12 (1998) Article DOI: 10.1038/35422 BindingDB Entry DOI: 10.7270/Q29P2ZW9
					More data for this Ligand-Target Pair