Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine protease 1 (Rattus norvegicus) | BDBM50110015 (CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | US Patent | 150 | -38.8 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50110015 (CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jena Curated by ChEMBL | Assay Description In vitro inhibition of trypsin. | Bioorg Med Chem Lett 12: 645-8 (2002) BindingDB Entry DOI: 10.7270/Q2NZ86XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM50110015 (CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | US Patent | 290 | -37.2 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair |