Compile Data Set for Download or QSAR

Found 149 hits of ic50 for UniProtKB: P08581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517021 ((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- hydroxypr...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CCC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517049 ((R)-5-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccc(F)cc5)c4=O)C4CC4)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517011 ((S)-N-(3-fluoro-4-((3- ((3-hydroxy-3- methylbutan-...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@@H](C)C(C)(C)O)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517014 ((R)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(CC5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517051 ((R)-5-bromo-N-(3- fluoro-4-((3-((1- hydroxypropan-...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(Br)cn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517044 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(cc(-c5ccc(F)cc5)c4=O)C(C)C)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517002 ((R)—N-(3-fluoro-4-((3-((1-hydroxypropan-2-yl)amino...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517082 ((S)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- methoxypr...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CCC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM516997 ((R)-N-(3-fluoro-4-((3- ((1-hydroxybutan-2- yl)amin...) Show SMILES CC[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517030 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccc(C)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517045 ((R)-1-ethyl-N-(3-fluoro- 4-((3-((1- hydroxypropan-...) Show SMILES CCn1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@H](C)CO)c34)c(F)c2)c(=O)c(c1)-c1ccc(F)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517080 ((S)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(CC5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517033 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(C)cn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517109 ((R)-1-(cyclopropylmethyl)-N-(3-fluoro-4-((3-((1-me...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(CC5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517009 (N-(3-fluoro-4-((3- (((2R,3R)-3- hydroxybutan-2- yl...) Show SMILES C[C@@H](O)[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517010 ((R)-N-(3-fluoro-4-((3- ((3-hydroxy-3- methylbutan-...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@H](C)C(C)(C)O)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517036 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(nn(-c5ccc(F)cc5)c4=O)C(C)C)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517084 ((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES CCn1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@@H](C)COC)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517091 ((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- methoxypr...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CCC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517037 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nn(C(C)C)c(=S)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517081 ((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccc(C)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517003 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)(me...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N(C)[C@H](C)CO)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517099 ((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(C)cn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517035 ((R)-6-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(nn(-c5ccc(F)cc5)c4=O)C4CC4)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517046 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C)cc(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517028 ((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517006 ((S)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...) Show SMILES C[C@H](O)CNc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM516981 (N-(4-((3-((4,4-difluoro-1- hydroxybutan-2- yl)amin...) Show SMILES OCC(CC(F)F)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517047 ((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C)cc(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517076 ((R)—N-(3-fluoro-4-((3-((1-methoxypropan-2-yl)amino...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517038 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM516998 ((S)-N-(3-fluoro-4-((3- ((1-hydroxybutan-2- yl)amin...) Show SMILES CC[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM516985 ((R)-N-(3-fluoro-4-((3-((1- hydroxybutan-2- yl)amin...) Show SMILES CC[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517094 (N-(4-((3-((4,4- difluorobutan-2- yl)amino)-1H- pyr...) Show SMILES CC(CC(F)F)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517007 (N-(3-fluoro-4-((3-((2- hydroxy-2- methylpropyl)ami...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(NCC(C)(C)O)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517034 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nccn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517090 ((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccc(C)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517005 ((R)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...) Show SMILES C[C@@H](O)CNc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517050 ((R)-1-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(C)cn(-c5ccc(F)c(F)c5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517102 ((S)-N-(4-((3-((1- ethoxypropan-2- yl)amino)-1H- py...) Show SMILES CCOC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(C)cn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517092 ((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517126 (N-(4-((3-amino-1H-pyrazolo[3,4-b]pyridin-4-yl)oxy)...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM516967 (N-(3-fluoro-4-((3- (((1s,3s)-3- (hydroxymethyl)cyc...) Show SMILES OC[C@H]1CC(C1)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r,wU:2.1,(-12.34,2.12,;-11.94,.63,;-10.45,.23,;-9.12,1,;-8.35,-.33,;-9.68,-1.1,;-6.86,-.73,;-6.46,-2.22,;-7.37,-3.47,;-6.46,-4.71,;-5,-4.23,;-3.67,-5,;-2.33,-4.23,;-2.33,-2.69,;-3.67,-1.93,;-3.67,-.38,;-2.33,.38,;-1,-.38,;.34,.38,;.34,1.93,;1.67,2.69,;3,1.93,;3,.38,;4.34,2.69,;4.34,4.23,;5.67,5,;7,4.23,;7,2.69,;8.34,1.93,;8.34,.38,;9.67,-.38,;11.01,.38,;12.34,-.38,;11.01,1.93,;9.67,2.69,;5.67,1.93,;5.67,.38,;-1,2.69,;-2.33,1.93,;-3.67,2.69,;-5,-2.69,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM516979 (N-(3-fluoro-4-((3-((1- hydroxy-4-methoxybutan- 2-y...) Show SMILES COCCC(CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)c(F)c5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517024 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES CCC(CC)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@H](C)CO)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517047 ((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C)cc(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517040 ((R)-1-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517093 ((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair

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