Compile Data Set for Download or QSAR

Found 43 hits of ec50 for UniProtKB: P70604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50561183 (CHEMBL4787693) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](C)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]3CSSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC3=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N2)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0240	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant rat SK2 expressed in HEK293 cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for 50 ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00300 BindingDB Entry DOI: 10.7270/Q24B351Z
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50561185 (CHEMBL4749661) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)N2)NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(N)=O)[C@@H](C)O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0270	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant rat SK2 expressed in HEK293 cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for 50 ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00300 BindingDB Entry DOI: 10.7270/Q24B351Z
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50561184 (CHEMBL4762592) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](C)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@H]3CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)CNC1=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC3=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N2)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.290	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant rat SK2 expressed in HEK293 cells assessed as decrease in intracellular calcium level at membrane potential -120 mV for 50 ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00300 BindingDB Entry DOI: 10.7270/Q24B351Z
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583213 (CHEMBL5086997) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2cc(Cl)ccc2F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	91	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells assessed as increase in calcium response at -90 mV holding potential measured at 1 to 2 days by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583211 (CHEMBL5078247) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(F)c(Cl)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells assessed as increase in calcium response at -90 mV holding potential measured at 1 to 2 days by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583213 (CHEMBL5086997) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2cc(Cl)ccc2F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	640	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583211 (CHEMBL5078247) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(F)c(Cl)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	990	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583210 (CHEMBL5074700) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2cc(F)ccc2F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583212 (CHEMBL5076878) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(Cl)cc2F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583214 (CHEMBL5076032) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2cc(F)ccc2Cl)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.97E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583216 (CHEMBL5081906) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(c(Cl)c2)C(F)(F)F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.27E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583215 (CHEMBL5075016) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(cc2)C(F)(F)F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583223 (CHEMBL5077913) Show SMILES Cc1nc(co1)-c1nc(C)cc(Nc2ccc(F)c(Cl)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.59E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583231 (CHEMBL5094656) Show SMILES Cc1cc(C)n(n1)-c1cc(C)c(Nc2ccc(F)c(Cl)c2)nn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.32E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583220 (CHEMBL5079766) Show SMILES Cc1cn(cn1)-c1nc(C)cc(Nc2cc(Cl)ccc2F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.51E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583209 (CHEMBL5082158) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2cccc(F)c2F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.03E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583219 (CHEMBL5088936) Show SMILES Cc1cc(C)n(n1)-c1nc(N)cc(Nc2ccc(F)c(Cl)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.59E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50275157 (CHEMBL453730 | N-cyclohexyl-2-(3,5-dimethyl-1H-pyr...) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(NC2CCCCC2)n1 Show InChI InChI=1S/C16H23N5/c1-11-10-15(18-14-7-5-4-6-8-14)19-16(17-11)21-13(3)9-12(2)20-21/h9-10,14H,4-8H2,1-3H3,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.48E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583222 (CHEMBL5094693) Show SMILES Cc1nc(co1)-c1nc(C)cc(Nc2cc(Cl)ccc2F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM168436 (US9675591, SKA-19) Show SMILES Nc1nc2ccc(SC(F)(F)F)cc2s1 Show InChI InChI=1S/C8H5F3N2S2/c9-8(10,11)15-4-1-2-5-6(3-4)14-7(12)13-5/h1-3H,(H2,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	7.35	25
The Regents of the University of California US Patent					Assay Description All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...				US Patent US9675591 (2017) BindingDB Entry DOI: 10.7270/Q26T0JSP
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583218 (CHEMBL5090801) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2cc(ccc2F)C(O)=O)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583221 (CHEMBL5088498) Show SMILES Cc1cn(cn1)-c1nc(C)cc(Nc2ccc(F)c(Cl)c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.88E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583199 (CHEMBL5074647) Show SMILES CO[C@@H]1CC[C@@H](CC1)Nc1cc(C)nc(n1)-n1nc(C)cc1C |r,wD:5.8,2.1,(69.87,-2.91,;68.53,-2.15,;67.2,-2.92,;67.21,-4.46,;65.88,-5.23,;64.54,-4.47,;64.54,-2.93,;65.87,-2.15,;63.21,-5.24,;63.21,-6.78,;61.88,-7.55,;61.88,-9.1,;60.55,-9.87,;63.22,-9.87,;64.55,-9.1,;64.55,-7.55,;65.89,-9.86,;67.3,-9.23,;68.33,-10.37,;69.86,-10.21,;67.56,-11.71,;66.05,-11.39,;64.91,-12.42,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.97E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583226 (CHEMBL5086120) Show SMILES Cc1cc(C)n(n1)-c1cc(Nc2cc(Cl)ccc2F)nc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583227 (CHEMBL5079837) Show SMILES Cc1cc(C)n(n1)-c1cc(Nc2ccc(Cl)cc2F)nc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583228 (CHEMBL5072517) Show SMILES Cc1cc(C)n(n1)-c1cc(Nc2cc(F)ccc2Cl)nc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583229 (CHEMBL5088379) Show SMILES Cc1cc(C)n(n1)-c1cc(Nc2cc(F)ccc2F)nc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583230 (CHEMBL5075803) Show SMILES Cc1cc(C)n(n1)-c1cc(Nc2ccc(c(Cl)c2)C(F)(F)F)nc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583196 (CHEMBL5084004) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H]2CC[C@H](O)CC2)n1 |r,wD:14.14,17.18,(12.25,-10.26,;10.72,-10.43,;9.95,-11.76,;8.44,-11.44,;7.3,-12.48,;8.28,-9.91,;9.69,-9.28,;6.94,-9.15,;5.61,-9.92,;4.27,-9.15,;2.94,-9.92,;4.28,-7.61,;5.6,-6.84,;5.6,-5.3,;6.93,-4.52,;6.93,-2.98,;8.26,-2.21,;9.59,-2.97,;10.92,-2.2,;9.6,-4.51,;8.27,-5.29,;6.94,-7.6,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583225 (CHEMBL5076140) Show SMILES Cc1cc(C)n(n1)-c1cc(Nc2ccc(F)c(Cl)c2)nc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583224 (CHEMBL5090420) Show SMILES Cc1cc(C)n(n1)-c1cc(Nc2cccc(Cl)c2)nc(N)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583217 (CHEMBL5084258) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2cc(Cl)cc(c2)C(F)(F)F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583197 (CHEMBL5079951) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H]2CC[C@H](N)CC2)n1 |r,wD:14.14,17.18,(30.83,-10.14,;29.3,-10.3,;28.53,-11.64,;27.02,-11.32,;25.88,-12.35,;26.86,-9.79,;28.27,-9.16,;25.53,-9.03,;24.19,-9.8,;22.85,-9.03,;21.52,-9.8,;22.86,-7.48,;24.18,-6.71,;24.18,-5.17,;25.51,-4.4,;25.51,-2.86,;26.84,-2.08,;28.17,-2.85,;29.51,-2.08,;28.18,-4.39,;26.85,-5.16,;25.52,-7.48,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583198 (CHEMBL5090455) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H]2CC[C@H](CO)CC2)n1 |r,wD:14.14,17.18,(49.78,-10.62,;48.25,-10.79,;47.48,-12.12,;45.97,-11.8,;44.83,-12.83,;45.81,-10.27,;47.21,-9.64,;44.47,-9.51,;43.13,-10.28,;41.8,-9.51,;40.47,-10.28,;41.8,-7.96,;43.13,-7.19,;43.13,-5.65,;44.46,-4.88,;44.45,-3.34,;45.78,-2.57,;47.12,-3.33,;48.45,-2.56,;49.79,-3.32,;47.13,-4.87,;45.79,-5.65,;44.47,-7.96,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583200 (CHEMBL5093708) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H]2CC[C@H](F)CC2)n1 |r,wD:14.14,17.18,(87.17,-10.49,;85.64,-10.65,;84.87,-11.99,;83.37,-11.67,;82.22,-12.7,;83.2,-10.14,;84.61,-9.51,;81.87,-9.38,;80.53,-10.15,;79.2,-9.38,;77.86,-10.15,;79.2,-7.83,;80.53,-7.06,;80.52,-5.52,;81.85,-4.75,;81.85,-3.21,;83.18,-2.43,;84.52,-3.2,;85.85,-2.43,;84.52,-4.74,;83.19,-5.51,;81.86,-7.83,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583208 (CHEMBL5089976) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(cc2)[N+]([O-])=O)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583207 (CHEMBL5088689) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(S)cc2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583206 (CHEMBL5079218) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H](Cc2ccc(F)c(F)c2)C(O)=O)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583205 (CHEMBL5069418) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H](Cc2ccc(O)cc2)C(O)=O)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583204 (CHEMBL5075501) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H](Cc2ccc(cc2)C#N)C(O)=O)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583203 (CHEMBL5081876) Show SMILES COc1cc2nc(Nc3cc(C)nc(n3)-n3nc(C)cc3C)[nH]c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583201 (CHEMBL5080805) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@H]2CC[C@H](CC2)[N+]([O-])=O)n1 |r,wD:14.14,17.21,(13.14,-30.4,;11.61,-30.56,;10.84,-31.9,;9.33,-31.58,;8.19,-32.61,;9.17,-30.05,;10.57,-29.42,;7.83,-29.29,;6.49,-30.06,;5.16,-29.29,;3.83,-30.06,;5.16,-27.74,;6.49,-26.97,;6.49,-25.43,;7.82,-24.66,;9.15,-25.42,;10.48,-24.65,;10.48,-23.11,;9.14,-22.34,;7.81,-23.12,;11.81,-22.34,;13.15,-23.1,;11.81,-20.79,;7.83,-27.74,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Rattus norvegicus (Rat))	BDBM50583202 (CHEMBL5083279) Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(NCCc2ccc(cc2)[N+]([O-])=O)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01473 BindingDB Entry DOI: 10.7270/Q28919R5
					More data for this Ligand-Target Pair