Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34046 (iodinated benzimidazole, 9a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 19 | -10.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34038 (4,5,6,7-tetraiodobenzimidazole (TIBI), 1a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MCE MMDB PC cid PC sid PDB UniChem | Article PubMed | 23 | -10.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34044 (iodinated benzimidazole, 7a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 24 | -10.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34051 (iodinated benzimidazole, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 27 | -10.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34052 (iodinated benzimidazole, 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 50 | -10.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34054 (iodinated benzimidazole, 17) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 50 | -10.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34053 (iodinated benzimidazole, 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 54 | -10.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34048 (iodinated benzimidazole, 11a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 70 | -10.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34043 (iodinated benzimidazole, 6a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 75 | -10.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34050 (iodinated benzimidazole, 13a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 90 | -9.99 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34040 (iodinated benzimidazole, 3a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 100 | -9.93 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34047 (iodinated benzimidazole, 10a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 120 | -9.81 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34049 (iodinated benzimidazole, 12a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 120 | -9.81 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34056 (iodinated benzimidazole, 23) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 130 | -9.77 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34055 (iodinated benzimidazole, 21) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 140 | -9.72 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34039 (iodinated benzimidazole, 2a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 160 | -9.64 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34058 (iodinated benzimidazole, 27) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 160 | -9.64 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34057 (iodinated benzimidazole, 25) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 180 | -9.56 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34045 (iodinated benzimidazole, 8a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 330 | -9.19 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34041 (iodinated benzimidazole, 4a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 460 | -8.99 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34042 (iodinated benzimidazole, 5a) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 590 | -8.83 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus (Rat)) | BDBM50156369 (CHEMBL227370) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Rattus norvegicus (rat) liver cytosolic CK2 | Citation and Details Article DOI: 10.1007/s00044-010-9533-9 BindingDB Entry DOI: 10.7270/Q2C2509N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34059 (brominated benzimidazole, 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | 1.34E+3 | -8.33 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34060 (brominated benzimidazole, 22) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.45E+3 | -8.28 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34062 (brominated benzimidazole, 26) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.51E+3 | -8.25 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase II subunit alpha (Rattus norvegicus (Rat)) | BDBM34061 (brominated benzimidazole, 24) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.91E+3 | -8.11 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
University of Padova | Assay Description Inhibitory effect of test compound was assessed in reaction buffer containing purified CK2, synthetic peptide substrate, and [gamma-33P]ATP. Assays w... | Bioorg Med Chem 17: 7281-9 (2009) Article DOI: 10.1016/j.bmc.2009.08.047 BindingDB Entry DOI: 10.7270/Q2NZ860P | |||||||||||
More data for this Ligand-Target Pair |