Found 50 hits of ic50 for UniProtKB: P33072 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633180
(4-((1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-2-methyl...)Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(cc23)C(=O)N2CCN(CC2)C(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cc1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633249
(N-((1-(4-(((1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-...)Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)C(OCc1ccc(cc1)-n1cc(CNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)nn1)c1cn(C\C(F)=C\CN)nn1 |r,w:13.13| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633181
(1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-3-(3-(N,N-di...)Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(cc23)C(=O)NCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cc1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633197
(N,N′-((((((((((5-(1-((Z)-4-amino-2-fluorobut...)Show SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(=O)Nc1ccc2n(Cc3cn(CCOCCOCCOCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)c(=O)n(Cc3cn(CCOCCOCCOCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)c2c1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633202
(N,N′-((((5-(1-((Z)-4-amino-2-fluorobut-2-en-...)Show SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(=O)Nc1ccc2n(CCn3cc(CCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)c(=O)n(CCn3cc(CCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)c2c1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633250
(N-((1-(4-(((1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-...)Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)C(OCc1ccc(cc1)-n1cc(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)nn1)c1cn(C\C(F)=C\CN)nn1 |r,w:13.13| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633203
(5-(1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-3-(3-(N,N...)Show SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(=O)Nc1cc(cc(c1)C(=O)NCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)NCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633204
(5-(4-(1-((Z)-4-amino-2-fluorobut-2-en-1-yl)-3-(3-(...)Show SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)-c1cn(nn1)-c1cc(cc(c1)C(=O)NCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)NCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633224
(4-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1ccc(cc1)C(=O)NCc1cn(CCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)nn1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633227
(2-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1ccccc1C(=O)NCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633233
(3-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1cccc(c1)C(=O)NCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633244
(3-(((Z)-4-amino-2-fluorobut-2-en-1-yl)sulfonyl)-N-...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1cccc(c1)C(=O)Nc1cc(cc(c1)C(=O)N1CCN(CC1)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)N1CCN(CC1)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633245
((3aS,4S,6aR)-4-(5-(4-(3-(3-(((Z)-4-amino-2-fluorob...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1cccc(OCCCc2cn(CCCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)nn2)c1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633246
((3aS,3a'S,4S,4'S,6aR,6a′R)-4,4′-(((((5...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1cccc(Cn2cc(nn2)-c2cc(OCCCc3cn(CCCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)cc(OCCCc3cn(CCCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)nn3)c2)c1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633247
((3aS,3a'S,4S,4'S,6aR,6a′R)-4,4′-(((((3...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1cccc(c1)N(CCCc1cn(CCCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)nn1)CCCc1cn(CCCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)nn1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM633248
((3aS,4S,6aR)-4-(4-(4-(3-((3-(((Z)-4-amino-2-fluoro...)Show SMILES NC\C=C(/F)CS(=O)(=O)c1cccc(NCCCc2cn(CCCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)nn2)c1 |r| | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505649
(CHEMBL4439437)Show SMILES Cl.C[C@H](NS(=O)(=O)c1ccc(OC\C(F)=C\CN)cc1)c1ccccc1 |r| Show InChI InChI=1S/C18H21FN2O3S.ClH/c1-14(15-5-3-2-4-6-15)21-25(22,23)18-9-7-17(8-10-18)24-13-16(19)11-12-20;/h2-11,14,21H,12-13,20H2,1H3;1H/b16-11-;/t14-;/m0./s1 | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505633
(CHEMBL4448713)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O Show InChI InChI=1S/C22H26FN3O4S2/c1-15-22(16-6-5-7-19(12-16)32(29,30)25(2)3)20-13-18(31(4,27)28)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505657
(CHEMBL4467234)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(NCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H21FN6O2S/c1-21(2)25(23,24)15-5-3-13(4-6-15)18-9-14-11-22(20-19-14)10-12(16)7-8-17/h3-7,11,18H,8-10,17H2,1-2H3/b12-7- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505655
(CHEMBL4441299)Show InChI InChI=1S/C13H15FN4O/c14-11(6-7-15)8-18-9-12(16-17-18)10-19-13-4-2-1-3-5-13/h1-6,9H,7-8,10,15H2/b11-6- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505659
(CHEMBL4459524)Show SMILES Cl.CC(C)(C)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C17H23FN4O/c1-17(2,3)13-4-6-16(7-5-13)23-12-15-11-22(21-20-15)10-14(18)8-9-19/h4-8,11H,9-10,12,19H2,1-3H3/b14-8- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505650
(CHEMBL4450939)Show SMILES Cl.CS(=O)(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C14H17FN4O3S/c1-23(20,21)14-4-2-13(3-5-14)22-10-12-9-19(18-17-12)8-11(15)6-7-16/h2-6,9H,7-8,10,16H2,1H3/b11-6- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505640
(CHEMBL4556859)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(Cc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H20FN5O2S/c1-20(2)24(22,23)15-5-3-12(4-6-15)9-14-11-21(19-18-14)10-13(16)7-8-17/h3-7,11H,8-10,17H2,1-2H3/b13-7- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505641
(CHEMBL4531248)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(cc1)-c1ccn(C\C(F)=C\CN)c1 Show InChI InChI=1S/C16H20FN3O2S/c1-19(2)23(21,22)16-5-3-13(4-6-16)14-8-10-20(11-14)12-15(17)7-9-18/h3-8,10-11H,9,12,18H2,1-2H3/b15-7- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505661
(CHEMBL4574820)Show SMILES Cl.CN(C)C(=O)c1ccc2c(c(C)n(C\C(F)=C\CN)c2c1)-c1cccc(c1)S(=O)(=O)N(C)C Show InChI InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-10-9-18(24(30)27(2)3)14-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505634
(CHEMBL4569453)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H20FN5O3S/c1-20(2)25(22,23)15-5-3-14(4-6-15)24-11-13-10-21(19-18-13)9-12(16)7-8-17/h3-7,10H,8-9,11,17H2,1-2H3/b12-7- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505647
(CHEMBL4531065)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)c(Cl)c1 Show InChI InChI=1S/C15H19ClFN5O3S/c1-21(2)26(23,24)13-3-4-15(14(16)7-13)25-10-12-9-22(20-19-12)8-11(17)5-6-18/h3-5,7,9H,6,8,10,18H2,1-2H3/b11-5- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505660
(CHEMBL4581561)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(cc1)-c1cn(C\C(F)=C\CN)nn1 Show InChI InChI=1S/C14H18FN5O2S/c1-19(2)23(21,22)13-5-3-11(4-6-13)14-10-20(18-17-14)9-12(15)7-8-16/h3-7,10H,8-9,16H2,1-2H3/b12-7- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505653
(CHEMBL4458907)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(NS(C)(=O)=O)cc12 Show InChI InChI=1S/C22H27FN4O4S2/c1-15-22(16-6-5-7-19(12-16)33(30,31)26(2)3)20-13-18(25-32(4,28)29)8-9-21(20)27(15)14-17(23)10-11-24/h5-10,12-13,25H,11,14,24H2,1-4H3/b17-10- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505636
(CHEMBL4443268)Show SMILES Cl.CS(=O)(=O)c1cccc(OCc2cn(C\C(F)=C\CN)nn2)c1 Show InChI InChI=1S/C14H17FN4O3S/c1-23(20,21)14-4-2-3-13(7-14)22-10-12-9-19(18-17-12)8-11(15)5-6-16/h2-5,7,9H,6,8,10,16H2,1H3/b11-5- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505658
(CHEMBL4581458)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cccnc12 Show InChI InChI=1S/C20H23FN4O2S/c1-14-19(15-6-4-7-17(12-15)28(26,27)24(2)3)20-18(8-5-11-23-20)25(14)13-16(21)9-10-22/h4-9,11-12H,10,13,22H2,1-3H3/b16-9- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505645
(CHEMBL4550754)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(O)cc12 Show InChI InChI=1S/C21H24FN3O3S/c1-14-21(15-5-4-6-18(11-15)29(27,28)24(2)3)19-12-17(26)7-8-20(19)25(14)13-16(22)9-10-23/h4-9,11-12,26H,10,13,23H2,1-3H3/b16-9- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505643
(CHEMBL4582216)Show SMILES Cl.CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505662
(CHEMBL4446643)Show SMILES Cl.COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C22H26FN3O3S/c1-15-22(16-6-5-7-19(12-16)30(27,28)25(2)3)20-13-18(29-4)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505638
(CHEMBL4457578)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505635
(CHEMBL4472333)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 Show InChI InChI=1S/C21H24FN3O2S/c1-15-21(16-7-6-8-18(13-16)28(26,27)24(2)3)19-9-4-5-10-20(19)25(15)14-17(22)11-12-23/h4-11,13H,12,14,23H2,1-3H3/b17-11- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505648
(CHEMBL4562149)Show SMILES Cl.C[C@H](NS(=O)(=O)c1ccc(OC\C(F)=C/CN)cc1)c1ccccc1 |r| Show InChI InChI=1S/C18H21FN2O3S.ClH/c1-14(15-5-3-2-4-6-15)21-25(22,23)18-9-7-17(8-10-18)24-13-16(19)11-12-20;/h2-11,14,21H,12-13,20H2,1H3;1H/b16-11+;/t14-;/m0./s1 | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50232678
(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...) | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505652
(CHEMBL4463296)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1ccn(C\C(F)=C\CN)c1 Show InChI InChI=1S/C16H20FN3O2S/c1-19(2)23(21,22)16-5-3-4-13(10-16)14-7-9-20(11-14)12-15(17)6-8-18/h3-7,9-11H,8,12,18H2,1-2H3/b15-6- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505639
(CHEMBL4554097)Show SMILES Cl.CN(C)C(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C16H20FN5O2/c1-21(2)16(23)12-3-5-15(6-4-12)24-11-14-10-22(20-19-14)9-13(17)7-8-18/h3-7,10H,8-9,11,18H2,1-2H3/b13-7- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505637
(CHEMBL4438235)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 Show InChI InChI=1S/C21H23ClFN3O2S/c1-14-21(15-5-4-6-18(11-15)29(27,28)25(2)3)19-12-16(22)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3/b17-9- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505654
(CHEMBL4586209)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H25N3O4S/c1-15-21(16-7-6-8-18(13-16)30(28,29)24(2)3)19-14-17(22(26)27)9-10-20(19)25(15)12-5-4-11-23/h4-10,13-14H,11-12,23H2,1-3H3,(H,26,27)/b5-4+ | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505642
(CHEMBL4527340)Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(cc1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 Show InChI InChI=1S/C21H24FN3O2S/c1-15-21(16-8-10-18(11-9-16)28(26,27)24(2)3)19-6-4-5-7-20(19)25(15)14-17(22)12-13-23/h4-12H,13-14,23H2,1-3H3/b17-12- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505651
(CHEMBL4469240)Show SMILES Cl.CS(=O)(=O)c1ccccc1OCc1cn(C\C(F)=C\CN)nn1 Show InChI InChI=1S/C14H17FN4O3S/c1-23(20,21)14-5-3-2-4-13(14)22-10-12-9-19(18-17-12)8-11(15)6-7-16/h2-6,9H,7-8,10,16H2,1H3/b11-6- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505663
(CHEMBL4451632)Show SMILES Cl.CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H28FN3O4S/c1-5-32-24(29)18-9-10-22-21(14-18)23(16(2)28(22)15-19(25)11-12-26)17-7-6-8-20(13-17)33(30,31)27(3)4/h6-11,13-14H,5,12,15,26H2,1-4H3/b19-11- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505656
(CHEMBL4457469)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(ccc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-8-7-16(22(27)28)12-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505646
(CHEMBL4446904)Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)-c1nnn[nH]1 Show InChI InChI=1S/C22H24FN7O2S/c1-14-21(15-5-4-6-18(11-15)33(31,32)29(2)3)19-12-16(22-25-27-28-26-22)7-8-20(19)30(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,25,26,27,28)/b17-9- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50505644
(CHEMBL4563012)Show SMILES Cl.CN(C)C(=O)c1cccc2c(c(C)n(C\C(F)=C\CN)c12)-c1cccc(c1)S(=O)(=O)N(C)C Show InChI InChI=1S/C24H29FN4O3S/c1-16-22(17-8-6-9-19(14-17)33(31,32)28(4)5)20-10-7-11-21(24(30)27(2)3)23(20)29(16)15-18(25)12-13-26/h6-12,14H,13,15,26H2,1-5H3/b18-12- | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaxis Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever... |
J Med Chem 62: 9874-9889 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2 |
More data for this
Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Bos taurus) | BDBM50589703
(CHEMBL5196906) | MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmcl.2022.128942
BindingDB Entry DOI: 10.7270/Q2639TQ8 |
More data for this
Ligand-Target Pair | |
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