Compile Data Set for Download or QSAR

Found 36 hits of ec50 for UniProtKB: P25084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50350703 (CHEMBL1814828) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCSC1=O |r| Show InChI InChI=1S/C16H27NO3S/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351512 (CHEMBL8483) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50080867 (CHEMBL3421671) Show SMILES [O-][N+](=O)c1ccccc1NC(=O)Cc1cc(Br)cc(Br)c1OC(=O)CCN1C(=O)CCC1=O Show InChI InChI=1S/C21H17Br2N3O7/c22-13-9-12(10-17(27)24-15-3-1-2-4-16(15)26(31)32)21(14(23)11-13)33-20(30)7-8-25-18(28)5-6-19(25)29/h1-4,9,11H,5-8,10H2,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli BL21 DE3 after 4 to 6 hrs by GFP reporter gene assay				ACS Med Chem Lett 6: 162-7 (2015) Article DOI: 10.1021/ml500459f BindingDB Entry DOI: 10.7270/Q2CV4KF1
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351512 (CHEMBL8483) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50350703 (CHEMBL1814828) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCSC1=O |r| Show InChI InChI=1S/C16H27NO3S/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351510 (CHEMBL8463) Show SMILES CCCCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O Show InChI InChI=1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducer				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351515 (CHEMBL1823932) Show SMILES CCCCC\C=C\CCC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H25NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h6-7,14H,2-5,8-12H2,1H3,(H,17,19)/b7-6+/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351510 (CHEMBL8463) Show SMILES CCCCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O Show InChI InChI=1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351513 (CHEMBL8450) Show SMILES CCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O Show InChI InChI=1S/C14H23NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h12H,2-10H2,1H3,(H,15,17)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50468430 (CHEMBL4283085) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCCC1=O |r| Show InChI InChI=1S/C17H29NO3/c1-2-3-4-5-6-7-8-10-14(19)13-17(21)18-15-11-9-12-16(15)20/h15H,2-13H2,1H3,(H,18,21)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50080869 (CHEMBL1236450) Show SMILES [O-][N+](=O)c1ccccc1C(=O)NCc1cc(Br)cc(Br)c1OC(=O)c1ccccc1Cl Show InChI InChI=1S/C21H13Br2ClN2O5/c22-13-9-12(11-25-20(27)15-6-2-4-8-18(15)26(29)30)19(16(23)10-13)31-21(28)14-5-1-3-7-17(14)24/h1-10H,11H2,(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR				ACS Med Chem Lett 6: 162-7 (2015) Article DOI: 10.1021/ml500459f BindingDB Entry DOI: 10.7270/Q2CV4KF1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50468428 (CHEBI:44612 | CHEMBL1234965) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCNC1=O |r| Show InChI InChI=1S/C16H28N2O3/c1-2-3-4-5-6-7-8-9-13(19)12-15(20)18-14-10-11-17-16(14)21/h14H,2-12H2,1H3,(H,17,21)(H,18,20)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351512 (CHEMBL8483) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR				ACS Med Chem Lett 6: 162-7 (2015) Article DOI: 10.1021/ml500459f BindingDB Entry DOI: 10.7270/Q2CV4KF1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351252 (CHEMBL8755) Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCOC1=O Show InChI InChI=1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351252 (CHEMBL8755) Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCOC1=O Show InChI InChI=1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducer				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351514 (CHEMBL8609) Show SMILES CCCCCCCCCC(O)CC(=O)N[C@H]1CCOC1=O Show InChI InChI=1S/C16H29NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h13-14,18H,2-12H2,1H3,(H,17,19)/t13?,14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50527017 (CHEMBL4461584) Show SMILES [O-][N+](=O)c1ccccc1C(=O)Oc1c(Br)cc(Br)cc1CNC(=O)c1ccccc1Cl Show InChI InChI=1S/C21H13Br2ClN2O5/c22-13-9-12(11-25-20(27)14-5-1-3-7-17(14)24)19(16(23)10-13)31-21(28)15-6-2-4-8-18(15)26(29)30/h1-10H,11H2,(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50468425 (CHEBI:56080 | CHEMBL208383) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@@H]1CCOC1=O Show InChI InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50080868 (CHEMBL3421670) Show SMILES [O-][N+](=O)c1ccccc1C(=O)NCc1cc(Br)cc(Br)c1OC(=O)CCCN1C(=O)CCC1=O Show InChI InChI=1S/C22H19Br2N3O7/c23-14-10-13(12-25-22(31)15-4-1-2-5-17(15)27(32)33)21(16(24)11-14)34-20(30)6-3-9-26-18(28)7-8-19(26)29/h1-2,4-5,10-11H,3,6-9,12H2,(H,25,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	119	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli BL21 DE3 after 4 to 6 hrs by GFP reporter gene assay				ACS Med Chem Lett 6: 162-7 (2015) Article DOI: 10.1021/ml500459f BindingDB Entry DOI: 10.7270/Q2CV4KF1
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351512 (CHEMBL8483) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	139	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351511 (CHEMBL463321) Show SMILES CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C12H19NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR cognate receptor expressed in Escherichia coli harboring pKDT17 assessed as activation of lasB expres...				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50468427 (CHEMBL1812101) Show SMILES CCCCCCCCCC(=O)CC(=O)NC1CCCC1 Show InChI InChI=1S/C17H31NO2/c1-2-3-4-5-6-7-8-13-16(19)14-17(20)18-15-11-9-10-12-15/h15H,2-14H2,1H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	162	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50468432 (CHEMBL4285396) Show SMILES CCCCCCCCCC(=O)CC(=O)NCC1CCCO1 Show InChI InChI=1S/C17H31NO3/c1-2-3-4-5-6-7-8-10-15(19)13-17(20)18-14-16-11-9-12-21-16/h16H,2-14H2,1H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	256	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50248862 (CHEMBL473592 | N-(3-oxo-3-phenylpropanoyl)-L-homos...) Show SMILES O=C(CC(=O)N[C@H]1CCOC1=O)Cc1ccccc1 |r| Show InChI InChI=1S/C14H15NO4/c16-11(8-10-4-2-1-3-5-10)9-13(17)15-12-6-7-19-14(12)18/h1-5,12H,6-9H2,(H,15,17)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR receptor expressed in Escherichia coli in absence of natural autoinducer				J Med Chem 53: 7467-89 (2010) Article DOI: 10.1021/jm901742e BindingDB Entry DOI: 10.7270/Q2S75GPT
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50468429 (CHEMBL4279608) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1 |r| Show InChI InChI=1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-15(18)12-16(19)17-14-10-11-20-13-14/h14H,2-13H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	906	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50468424 (CHEMBL4287516) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCO[C@@H]1O |r| Show InChI InChI=1S/C16H29NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14,16,20H,2-12H2,1H3,(H,17,19)/t14-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa LasR expressed in Escherichia coli JLD271 harboring LasR expression plasmid pJN105L and lasI-lacZ transcri...				Bioorg Med Chem 26: 5336-5342 (2018) Article DOI: 10.1016/j.bmc.2018.05.018 BindingDB Entry DOI: 10.7270/Q23B62V9
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50526977 (CHEMBL4462112) Show SMILES O=C(CSC#N)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C9H10N2O4S/c10-5-16-4-6(12)3-8(13)11-7-1-2-15-9(7)14/h7H,1-4H2,(H,11,13)/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50350703 (CHEMBL1814828) Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCSC1=O |r| Show InChI InChI=1S/C16H27NO3S/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa PAO1 MW1 (pUM15) LasR after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHL				Bioorg Med Chem 19: 4820-8 (2011) Article DOI: 10.1016/j.bmc.2011.06.071 BindingDB Entry DOI: 10.7270/Q27D2W47
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50527004 (CHEMBL4450449) Show SMILES Brc1cccc(OCC(=O)N[C@H]2CCSC2=O)c1 |r| Show InChI InChI=1S/C12H12BrNO3S/c13-8-2-1-3-9(6-8)17-7-11(15)14-10-4-5-18-12(10)16/h1-3,6,10H,4-5,7H2,(H,14,15)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50350705 (CHEMBL1814827) Show SMILES CCCC(=O)CC(=O)N[C@H]1CCSC1=O |r| Show InChI InChI=1S/C10H15NO3S/c1-2-3-7(12)6-9(13)11-8-4-5-15-10(8)14/h8H,2-6H2,1H3,(H,11,13)/t8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa PAO1 MW1 (pUM15) LasR after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHL				Bioorg Med Chem 19: 4820-8 (2011) Article DOI: 10.1016/j.bmc.2011.06.071 BindingDB Entry DOI: 10.7270/Q27D2W47
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50527002 (CHEMBL4444462) Show SMILES CCC(=O)CC(=O)Nc1ccccc1O Show InChI InChI=1S/C11H13NO3/c1-2-8(13)7-11(15)12-9-5-3-4-6-10(9)14/h3-6,14H,2,7H2,1H3,(H,12,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50350706 (CHEMBL1811922) Show SMILES CCCCCCCCCCCC(=O)N[C@H]1CCSC1=O |r| Show InChI InChI=1S/C16H29NO2S/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Agonist activity at Pseudomonas aeruginosa PAO1 MW1 (pUM15) LasR after 8 hrs by beta-galactosidase reporter gene assay relative to OdDHL				Bioorg Med Chem 19: 4820-8 (2011) Article DOI: 10.1016/j.bmc.2011.06.071 BindingDB Entry DOI: 10.7270/Q27D2W47
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50266165 ((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...) Show SMILES FC(F)(F)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50351511 (CHEMBL463321) Show SMILES CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C12H19NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50241433 ((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...) Show SMILES Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair
Transcriptional activator protein LasR (Pseudomonas aeruginosa)	BDBM50527003 (CHEMBL4522587) Show SMILES CCC(=O)CC(=O)NC1CCCCC1=O Show InChI InChI=1S/C11H17NO3/c1-2-8(13)7-11(15)12-9-5-3-4-6-10(9)14/h9H,2-7H2,1H3,(H,12,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
Larkin University Curated by ChEMBL					Assay Description Activation of LasR in Pseudomonas aeruginosa PAO-JP2 harboring plasI-LVAgfp incubated for 6 hrs by fluorescence method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115282 BindingDB Entry DOI: 10.7270/Q2PN992D
					More data for this Ligand-Target Pair