Compile Data Set for Download or QSAR

Found 160 hits of ic50 for UniProtKB: P28776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578623 (CHEMBL4858888) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(C)NC(=O)c1ccc(Cl)cc1)n1cnc2cc(F)c(F)cc12 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578625 (CHEMBL4855340) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:4.7,wD:1.0,18.21,(31.16,-49.31,;31.94,-50.76,;33.11,-51.77,;34.58,-51.26,;34.85,-49.74,;33.69,-48.73,;32.23,-49.24,;36.31,-49.23,;36.59,-47.71,;38.05,-47.2,;39.23,-48.21,;38.93,-49.73,;40.14,-50.67,;39.94,-52.19,;38.51,-52.78,;38.3,-54.3,;37.29,-51.83,;37.51,-50.31,;30.48,-51.26,;30.19,-52.77,;29.32,-50.25,;27.86,-50.76,;29.61,-48.74,;28.44,-47.73,;28.74,-46.23,;27.58,-45.22,;26.12,-45.72,;24.95,-44.72,;25.83,-47.25,;27,-48.25,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50550026 (CHEMBL4786690) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,18.21,wD:1.0,(55.56,-25.24,;55.58,-26.78,;54.24,-26.01,;52.9,-26.78,;52.91,-28.32,;54.25,-29.09,;55.57,-28.32,;51.57,-29.08,;50.24,-28.32,;48.91,-29.1,;48.92,-30.63,;50.25,-31.38,;50.25,-32.93,;51.58,-33.7,;52.92,-32.93,;54.25,-33.69,;52.91,-31.38,;51.58,-30.61,;56.91,-26.01,;56.91,-24.47,;58.24,-26.78,;58.24,-28.32,;56.9,-29.08,;59.58,-29.09,;59.57,-30.63,;60.9,-31.4,;62.24,-30.63,;63.57,-31.4,;62.23,-29.09,;60.9,-28.32,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50391363 (CHEMBL2148074) Show SMILES Oc1ccc(Cl)cc1-c1c[nH]nn1 Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50550026 (CHEMBL4786690) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,18.21,wD:1.0,(55.56,-25.24,;55.58,-26.78,;54.24,-26.01,;52.9,-26.78,;52.91,-28.32,;54.25,-29.09,;55.57,-28.32,;51.57,-29.08,;50.24,-28.32,;48.91,-29.1,;48.92,-30.63,;50.25,-31.38,;50.25,-32.93,;51.58,-33.7,;52.92,-32.93,;54.25,-33.69,;52.91,-31.38,;51.58,-30.61,;56.91,-26.01,;56.91,-24.47,;58.24,-26.78,;58.24,-28.32,;56.9,-29.08,;59.58,-29.09,;59.57,-30.63,;60.9,-31.4,;62.24,-30.63,;63.57,-31.4,;62.23,-29.09,;60.9,-28.32,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs by				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00668 BindingDB Entry DOI: 10.7270/Q2TM7FR5
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578624 (CHEMBL4856710) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(C)NC(=O)c1ccc(Cl)cc1)c1ccnc2ccc(F)cc12 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559669 (CHEMBL4756822) Show SMILES CCC([C@H]1CC[C@H](CC1)c1ccnc2ccc(cc12)C(F)(F)F)c1nc2ncc(Cl)cc2[nH]1 |r,wU:6.9,3.2,(5.53,-5.77,;5.53,-7.31,;6.87,-8.07,;6.87,-9.62,;8.2,-10.39,;8.2,-11.94,;6.87,-12.7,;5.53,-11.94,;5.53,-10.39,;6.87,-14.25,;5.52,-15.02,;5.52,-16.57,;6.87,-17.35,;8.21,-16.56,;9.55,-17.33,;10.88,-16.55,;10.87,-15,;9.53,-14.24,;8.21,-15.02,;12.2,-14.22,;13.54,-14.98,;12.19,-12.68,;13.53,-13.44,;8.2,-7.31,;8.2,-5.76,;9.66,-5.28,;10.29,-3.87,;11.82,-3.71,;12.72,-4.96,;14.26,-4.78,;12.09,-6.36,;10.56,-6.53,;9.66,-7.77,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559672 (CHEMBL4750211) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)C(CC)c1nc2ccc(Cl)cc2[nH]1 |r,wU:4.7,wD:1.0,(4.71,-8.61,;6.22,-8.87,;4.89,-9.64,;4.89,-11.19,;6.22,-11.96,;7.56,-11.19,;7.56,-9.64,;6.22,-13.51,;4.89,-14.28,;4.89,-15.82,;6.23,-16.59,;7.56,-15.82,;8.88,-16.59,;10.22,-15.82,;10.23,-14.27,;11.56,-13.49,;8.88,-13.51,;7.56,-14.27,;6.22,-7.32,;4.89,-6.55,;4.89,-5.02,;7.56,-6.56,;7.56,-5.01,;9.02,-4.53,;9.65,-3.12,;11.18,-2.96,;12.08,-4.21,;13.62,-4.03,;11.45,-5.61,;9.92,-5.78,;9.02,-7.02,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50550030 (CHEMBL4743409) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)NC(=O)c1ccc(cc1)-c1ccccc1 |r,wU:4.7,18.21,wD:1.0,(9.78,-48.44,;9.8,-49.98,;8.46,-49.21,;7.12,-49.98,;7.13,-51.52,;8.47,-52.29,;9.79,-51.52,;5.79,-52.29,;4.46,-51.52,;3.14,-52.3,;3.15,-53.83,;4.47,-54.58,;4.47,-56.13,;5.8,-56.9,;7.14,-56.13,;8.47,-56.9,;7.13,-54.58,;5.8,-53.82,;11.13,-49.21,;11.13,-47.67,;12.47,-49.98,;12.46,-51.52,;11.12,-52.29,;13.8,-52.3,;13.79,-53.83,;15.12,-54.6,;16.46,-53.83,;16.46,-52.29,;15.12,-51.52,;17.78,-54.6,;17.78,-56.14,;19.11,-56.91,;20.45,-56.14,;20.45,-54.59,;19.11,-53.83,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs by				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00668 BindingDB Entry DOI: 10.7270/Q2TM7FR5
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571886 (CHEMBL4861763) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccncc1C)[C@@H](C)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,14.16,wD:1.0,(48.54,-31.73,;48.95,-33.21,;47.63,-32.44,;46.29,-33.21,;46.29,-34.76,;47.63,-35.52,;48.95,-34.76,;44.96,-35.53,;43.62,-34.76,;42.29,-35.53,;42.29,-37.08,;43.64,-37.83,;44.97,-37.06,;46.3,-37.82,;50.29,-32.45,;50.29,-30.91,;51.62,-33.22,;51.62,-34.76,;50.28,-35.53,;52.95,-35.54,;52.94,-37.08,;54.27,-37.85,;55.61,-37.09,;56.94,-37.86,;55.61,-35.54,;54.28,-34.77,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571884 (CHEMBL4859400) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(F)c1C)[C@@H](C)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,15.17,wD:1.0,(7.89,-49.37,;8.3,-50.85,;6.98,-50.08,;5.64,-50.85,;5.64,-52.39,;6.98,-53.16,;8.3,-52.39,;4.31,-53.17,;2.98,-52.39,;1.64,-53.17,;1.64,-54.71,;2.99,-55.47,;3,-57,;4.32,-54.7,;5.65,-55.46,;9.64,-50.09,;9.64,-48.55,;10.97,-50.86,;10.97,-52.4,;9.63,-53.17,;12.3,-53.18,;12.29,-54.72,;13.62,-55.49,;14.96,-54.73,;16.29,-55.49,;14.96,-53.18,;13.63,-52.41,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50285416 (CHEMBL4161733) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:18.21,1.0,wD:4.7,(66.16,-9.22,;66.17,-7.68,;66.16,-6.15,;67.5,-5.38,;68.84,-6.15,;68.83,-7.69,;67.5,-8.46,;70.18,-5.39,;71.5,-6.16,;72.84,-5.4,;72.84,-3.85,;71.5,-3.08,;71.5,-1.55,;70.17,-.79,;68.84,-1.56,;67.5,-.8,;68.85,-3.09,;70.18,-3.85,;64.83,-8.46,;64.84,-10,;63.5,-7.69,;63.49,-6.14,;62.16,-8.46,;60.83,-7.69,;59.49,-8.47,;58.15,-7.69,;58.16,-6.14,;56.82,-5.38,;59.49,-5.38,;60.83,-6.14,)| Show InChI InChI=1S/C24H24ClFN2O/c1-15(24(29)28-20-9-6-18(25)7-10-20)16-2-4-17(5-3-16)21-12-13-27-23-11-8-19(26)14-22(21)23/h6-17H,2-5H2,1H3,(H,28,29)/t15-,16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs by				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00668 BindingDB Entry DOI: 10.7270/Q2TM7FR5
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559671 (CHEMBL4750659) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)C(CC)c1nc2ncc(Cl)cc2[nH]1 |r,wU:4.7,wD:1.0,(4.82,-9.26,;6.33,-9.52,;5,-10.3,;5,-11.84,;6.33,-12.61,;7.67,-11.84,;7.67,-10.3,;6.33,-14.16,;5,-14.93,;5,-16.47,;6.34,-17.24,;7.66,-16.47,;8.99,-17.24,;10.33,-16.47,;10.34,-14.92,;11.67,-14.14,;8.99,-14.16,;7.67,-14.93,;6.33,-7.98,;5,-7.21,;5,-5.67,;7.67,-7.21,;7.67,-5.66,;9.13,-5.18,;9.76,-3.77,;11.29,-3.61,;12.19,-4.86,;13.73,-4.68,;11.56,-6.26,;10.03,-6.43,;9.13,-7.68,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50285416 (CHEMBL4161733) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:18.21,1.0,wD:4.7,(66.16,-9.22,;66.17,-7.68,;66.16,-6.15,;67.5,-5.38,;68.84,-6.15,;68.83,-7.69,;67.5,-8.46,;70.18,-5.39,;71.5,-6.16,;72.84,-5.4,;72.84,-3.85,;71.5,-3.08,;71.5,-1.55,;70.17,-.79,;68.84,-1.56,;67.5,-.8,;68.85,-3.09,;70.18,-3.85,;64.83,-8.46,;64.84,-10,;63.5,-7.69,;63.49,-6.14,;62.16,-8.46,;60.83,-7.69,;59.49,-8.47,;58.15,-7.69,;58.16,-6.14,;56.82,-5.38,;59.49,-5.38,;60.83,-6.14,)| Show InChI InChI=1S/C24H24ClFN2O/c1-15(24(29)28-20-9-6-18(25)7-10-20)16-2-4-17(5-3-16)21-12-13-27-23-11-8-19(26)14-22(21)23/h6-17H,2-5H2,1H3,(H,28,29)/t15-,16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578625 (CHEMBL4855340) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:4.7,wD:1.0,18.21,(31.16,-49.31,;31.94,-50.76,;33.11,-51.77,;34.58,-51.26,;34.85,-49.74,;33.69,-48.73,;32.23,-49.24,;36.31,-49.23,;36.59,-47.71,;38.05,-47.2,;39.23,-48.21,;38.93,-49.73,;40.14,-50.67,;39.94,-52.19,;38.51,-52.78,;38.3,-54.3,;37.29,-51.83,;37.51,-50.31,;30.48,-51.26,;30.19,-52.77,;29.32,-50.25,;27.86,-50.76,;29.61,-48.74,;28.44,-47.73,;28.74,-46.23,;27.58,-45.22,;26.12,-45.72,;24.95,-44.72,;25.83,-47.25,;27,-48.25,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered twice da...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571885 (CHEMBL4877466) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(C)c1C)[C@@H](C)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,15.17,wD:1.0,(67.15,-31.42,;67.56,-32.91,;66.24,-32.13,;64.9,-32.91,;64.9,-34.45,;66.24,-35.21,;67.56,-34.45,;63.57,-35.22,;62.23,-34.45,;60.9,-35.22,;60.9,-36.77,;62.25,-37.52,;62.26,-39.06,;63.58,-36.75,;64.91,-37.52,;68.9,-32.14,;68.9,-30.6,;70.23,-32.91,;70.23,-34.45,;68.89,-35.22,;71.56,-35.23,;71.55,-36.77,;72.88,-37.54,;74.22,-36.78,;75.55,-37.55,;74.22,-35.23,;72.89,-34.46,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571881 (CHEMBL4845988) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(OC)c1C(F)F)[C@@H](CC)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,18.20,wD:1.0,(66.33,-47.56,;66.74,-49.04,;65.42,-48.27,;64.08,-49.04,;64.08,-50.59,;65.42,-51.35,;66.74,-50.59,;62.75,-51.36,;61.41,-50.59,;60.08,-51.36,;60.08,-52.91,;61.43,-53.66,;61.44,-55.2,;60.12,-55.97,;62.76,-52.89,;64.09,-53.65,;65.41,-52.88,;64.09,-55.19,;68.08,-48.28,;68.08,-46.74,;69.41,-45.98,;69.41,-49.05,;69.41,-50.59,;68.07,-51.36,;70.74,-51.37,;70.73,-52.91,;72.06,-53.68,;73.4,-52.92,;74.73,-53.69,;73.4,-51.37,;72.07,-50.6,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559678 (CHEMBL4763467) Show SMILES CCC(Nc1nnc(o1)-c1ccc(OC)cc1)[C@H]1CC[C@H](CC1)c1ccnc2ccc(cc12)C(F)(F)F |r,wU:20.25,17.18,(3.21,-6.32,;4.54,-5.54,;5.87,-6.32,;7.22,-5.54,;8.55,-6.32,;8.88,-7.82,;10.42,-7.99,;11.04,-6.61,;9.89,-5.54,;12.53,-6.21,;12.93,-4.73,;14.42,-4.33,;15.51,-5.42,;17,-5.02,;17.4,-3.53,;15.11,-6.9,;13.63,-7.31,;5.87,-7.86,;7.22,-8.63,;7.22,-10.18,;5.87,-10.95,;4.54,-10.18,;4.54,-8.63,;5.87,-12.49,;4.54,-13.26,;4.54,-14.8,;5.89,-15.58,;7.21,-14.8,;8.55,-15.56,;9.87,-14.78,;9.87,-13.25,;8.53,-12.5,;7.22,-13.26,;11.2,-12.49,;12.54,-13.26,;11.21,-10.95,;12.53,-11.71,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571883 (CHEMBL4868709) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(OC)c1C)[C@@H](CC)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,16.18,wD:1.0,(28.06,-49.01,;28.46,-50.5,;27.14,-49.72,;25.81,-50.5,;25.81,-52.04,;27.14,-52.81,;28.46,-52.04,;24.48,-52.82,;23.14,-52.04,;21.81,-52.82,;21.81,-54.36,;23.16,-55.12,;23.17,-56.65,;21.84,-57.42,;24.48,-54.34,;25.81,-55.11,;29.8,-49.73,;29.81,-48.19,;31.14,-47.43,;31.14,-50.51,;31.13,-52.05,;29.79,-52.82,;32.46,-52.82,;32.45,-54.36,;33.78,-55.13,;35.12,-54.37,;36.46,-55.14,;35.12,-52.82,;33.79,-52.05,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50549535 (CHEMBL4763375) Show SMILES [H][C@@]1(CC[C@@]2(COc3cc(ccc23)C(F)(F)F)CC1)[C@H](C)C(=O)Nc1ccc(Cl)cc1 |r,wU:4.4,19.22,wD:1.0,(49.52,-49.21,;49.47,-50.71,;50.8,-49.93,;52.14,-50.7,;52.14,-52.25,;53.43,-51.41,;54.62,-52.38,;54.07,-53.81,;54.76,-55.17,;53.93,-56.45,;52.39,-56.37,;51.7,-55,;52.54,-53.72,;54.62,-57.81,;55.95,-57.04,;55.96,-58.58,;53.79,-59.11,;50.8,-53.03,;49.47,-52.25,;48.13,-49.95,;48.12,-48.41,;46.79,-50.72,;46.79,-52.27,;45.45,-49.96,;44.12,-50.73,;44.12,-52.29,;42.78,-53.07,;41.44,-52.29,;40.1,-53.06,;41.44,-50.74,;42.77,-49.97,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse IDO1 expressed in HEK cells				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127738 BindingDB Entry DOI: 10.7270/Q270851B
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50514760 (CHEMBL4448402) Show SMILES O=C(NCc1cccc(Cn2cnc3ccccc23)c1)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C24H20N4O/c29-24(22-13-19-8-1-2-9-20(19)27-22)25-14-17-6-5-7-18(12-17)15-28-16-26-21-10-3-4-11-23(21)28/h1-13,16,27H,14-15H2,(H,25,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysis				J Med Chem 63: 3047-3065 (2020) Article DOI: 10.1021/acs.jmedchem.9b01809 BindingDB Entry DOI: 10.7270/Q29K4FKS
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571880 (CHEMBL4851220) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(OC)c1C(F)F)[C@@H](COC)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,18.20,wD:1.0,(10.11,-4.67,;10.52,-6.16,;9.2,-5.38,;7.87,-6.16,;7.87,-7.7,;9.2,-8.46,;10.52,-7.7,;6.54,-8.47,;5.2,-7.7,;3.86,-8.47,;3.87,-10.02,;5.21,-10.77,;5.22,-12.31,;3.9,-13.08,;6.54,-10,;7.87,-10.77,;9.2,-10,;7.88,-12.3,;11.86,-5.39,;11.86,-3.85,;13.2,-3.09,;13.2,-1.56,;13.19,-6.16,;13.19,-7.71,;11.85,-8.48,;14.52,-8.48,;14.51,-10.02,;15.84,-10.79,;17.18,-10.03,;18.52,-10.8,;17.18,-8.48,;15.85,-7.71,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50550037 (CHEMBL4755937) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)c1nc2ccc(Cl)cc2[nH]1 |r,wU:4.7,18.21,wD:1.0,(5,-8.36,;6.52,-8.62,;5.18,-9.39,;5.18,-10.94,;6.52,-11.71,;7.85,-10.94,;7.85,-9.39,;6.52,-13.26,;5.18,-14.03,;5.18,-15.56,;6.52,-16.34,;7.85,-15.57,;9.18,-16.34,;10.52,-15.57,;10.52,-14.02,;11.86,-13.24,;9.18,-13.26,;7.85,-14.03,;6.52,-7.07,;5.18,-6.31,;7.85,-6.31,;7.85,-4.76,;9.32,-4.28,;9.94,-2.87,;11.47,-2.71,;12.37,-3.96,;13.92,-3.78,;11.75,-5.36,;10.22,-5.53,;9.31,-6.77,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs by				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00668 BindingDB Entry DOI: 10.7270/Q2TM7FR5
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50550037 (CHEMBL4755937) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)c1nc2ccc(Cl)cc2[nH]1 |r,wU:4.7,18.21,wD:1.0,(5,-8.36,;6.52,-8.62,;5.18,-9.39,;5.18,-10.94,;6.52,-11.71,;7.85,-10.94,;7.85,-9.39,;6.52,-13.26,;5.18,-14.03,;5.18,-15.56,;6.52,-16.34,;7.85,-15.57,;9.18,-16.34,;10.52,-15.57,;10.52,-14.02,;11.86,-13.24,;9.18,-13.26,;7.85,-14.03,;6.52,-7.07,;5.18,-6.31,;7.85,-6.31,;7.85,-4.76,;9.32,-4.28,;9.94,-2.87,;11.47,-2.71,;12.37,-3.96,;13.92,-3.78,;11.75,-5.36,;10.22,-5.53,;9.31,-6.77,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50514753 (CHEMBL4557994) Show SMILES Brc1c[nH]c(c1)C(=O)NCc1cccc(Cn2cnc3ccccc23)c1 Show InChI InChI=1S/C20H17BrN4O/c21-16-9-18(22-11-16)20(26)23-10-14-4-3-5-15(8-14)12-25-13-24-17-6-1-2-7-19(17)25/h1-9,11,13,22H,10,12H2,(H,23,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ del Piemonte Orientale Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 transfected in P815 cells assessed as reduction in L-Kyn level measured after 16 hrs by HPLC analysis				J Med Chem 63: 3047-3065 (2020) Article DOI: 10.1021/acs.jmedchem.9b01809 BindingDB Entry DOI: 10.7270/Q29K4FKS
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559681 (CHEMBL4750132) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)Nc1nnc(o1)-c1ccc(OC)cc1 |wU:4.7,18.21,wD:1.0,(1.38,-4.24,;2.86,-4.64,;1.53,-5.41,;1.53,-6.95,;2.86,-7.72,;4.2,-6.95,;4.2,-5.41,;2.86,-9.26,;1.53,-10.02,;1.53,-11.56,;2.87,-12.34,;4.2,-11.56,;5.54,-12.33,;6.86,-11.55,;6.85,-10.02,;8.18,-9.25,;5.52,-9.26,;4.2,-10.03,;2.86,-3.1,;1.53,-2.33,;4.2,-2.33,;5.53,-3.1,;5.86,-4.59,;7.4,-4.76,;8.02,-3.39,;6.86,-2.33,;9.51,-2.99,;9.91,-1.51,;11.39,-1.11,;12.48,-2.2,;13.97,-1.8,;14.37,-.31,;12.09,-3.68,;10.6,-4.09,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578622 (CHEMBL4861332) Show SMILES [H][C@]12C[C@@H](C[C@@]1([H])[C@]2([H])[C@@H](CC)NC(=O)c1ccc(Cl)cc1)n1cnc2cc(F)c(F)cc12 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571879 (CHEMBL4848094) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(OC)c1C(F)F)[C@@H](CC)NC(=O)c1ccc(OC)nc1 |r,wU:4.7,18.20,wD:1.0,(34.27,-3.48,;34.68,-4.96,;33.36,-4.19,;32.03,-4.96,;32.03,-6.5,;33.36,-7.27,;34.68,-6.5,;30.7,-7.28,;29.36,-6.51,;28.03,-7.28,;28.03,-8.82,;29.37,-9.58,;29.38,-11.12,;28.06,-11.89,;30.7,-8.81,;32.03,-9.57,;33.36,-8.8,;32.04,-11.11,;36.02,-4.2,;36.03,-2.66,;37.36,-1.9,;37.35,-4.97,;37.35,-6.51,;36.01,-7.28,;38.68,-7.29,;40.01,-6.52,;41.34,-7.29,;41.34,-8.84,;42.68,-9.61,;42.68,-11.14,;40,-9.6,;38.67,-8.83,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571887 (CHEMBL4859579) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(C)c1)[C@@H](C)NC(=O)c1ccc(Cl)cc1 |r,wU:14.16,1.0,wD:4.7,(28.48,-32.3,;28.88,-33.79,;28.88,-35.33,;27.56,-36.1,;26.23,-35.33,;26.23,-33.79,;27.56,-33.01,;24.9,-36.11,;23.56,-35.33,;22.23,-36.11,;22.23,-37.65,;23.58,-38.41,;23.59,-39.94,;24.9,-37.64,;30.22,-33.03,;30.23,-31.48,;31.56,-33.8,;31.55,-35.34,;30.21,-36.11,;32.88,-36.12,;32.87,-37.65,;34.2,-38.42,;35.54,-37.66,;36.88,-38.43,;35.54,-36.11,;34.21,-35.34,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50391358 (CHEMBL2147989) Show SMILES Clc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6ClN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50550028 (CHEMBL4747228) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)NC(=O)c1ccc(OC)c(c1)N1CCOCC1 |r,wU:4.7,18.21,wD:1.0,(28.54,-48.21,;28.56,-49.75,;27.22,-48.98,;25.88,-49.75,;25.89,-51.29,;27.23,-52.06,;28.55,-51.29,;24.55,-52.06,;23.22,-51.3,;21.89,-52.07,;21.91,-53.6,;23.23,-54.36,;23.23,-55.9,;24.56,-56.67,;25.9,-55.9,;27.23,-56.67,;25.89,-54.35,;24.56,-53.59,;29.89,-48.99,;29.89,-47.45,;31.22,-49.76,;31.22,-51.29,;29.88,-52.06,;32.56,-52.07,;32.55,-53.61,;33.88,-54.38,;35.22,-53.61,;36.55,-54.38,;36.55,-55.92,;35.21,-52.06,;33.88,-51.3,;36.54,-51.29,;37.88,-52.06,;39.2,-51.3,;39.21,-49.76,;37.87,-48.99,;36.53,-49.76,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs by				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00668 BindingDB Entry DOI: 10.7270/Q2TM7FR5
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559680 (CHEMBL4780978) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)c1nc2cc(F)ccc2[nH]1 |wU:4.7,18.21,wD:1.0,(2.35,-2.85,;3.84,-3.25,;2.51,-4.02,;2.51,-5.56,;3.84,-6.33,;5.18,-5.56,;5.18,-4.02,;3.84,-7.87,;2.51,-8.64,;2.51,-10.18,;3.85,-10.95,;5.18,-10.18,;6.51,-10.94,;7.83,-10.16,;7.83,-8.64,;9.16,-7.87,;6.5,-7.88,;5.18,-8.64,;3.84,-1.71,;2.51,-.94,;5.18,-.94,;5.18,.6,;6.68,1.07,;7.29,2.43,;8.79,2.58,;9.56,3.92,;9.67,1.37,;9.06,-0,;7.56,-.15,;6.64,-1.4,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50391359 (CHEMBL2147998) Show SMILES Oc1ccccc1-c1c[nH]nn1 Show InChI InChI=1S/C8H7N3O/c12-8-4-2-1-3-6(8)7-5-9-11-10-7/h1-5,12H,(H,9,10,11)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571882 (CHEMBL4860353) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc(OC)c1F)[C@@H](CC)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,16.18,wD:1.0,(48.04,-48.32,;48.45,-49.8,;47.12,-49.03,;45.79,-49.8,;45.79,-51.34,;47.12,-52.11,;48.45,-51.34,;44.46,-52.12,;43.12,-51.35,;41.79,-52.12,;41.79,-53.66,;43.14,-54.42,;43.15,-55.96,;41.83,-56.73,;44.47,-53.65,;45.8,-54.41,;49.78,-49.04,;49.79,-47.5,;51.12,-46.74,;51.12,-49.81,;51.11,-51.35,;49.78,-52.12,;52.45,-52.13,;52.43,-53.67,;53.77,-54.44,;55.11,-53.68,;56.44,-54.45,;55.11,-52.13,;53.77,-51.36,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578649 (CHEMBL4866113) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(CC)NC(=O)c1ccc(Cl)cc1)n1cnc2cc(F)ccc12 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse Panc02 cells incubated for 48 hrs by RFMS method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578626 (CHEMBL4870435) Show SMILES CC1(C)CN(CC[C@@]11NC(=O)NC1=O)c1cc(cc2cncn12)C(F)(F)F |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578621 (CHEMBL4853212) Show SMILES CC1(C)CN(CC[C@]11NC(=O)NC1=O)c1cc(cc2cncn12)C(F)(F)F |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50578624 (CHEMBL4856710) Show SMILES [H][C@@]12C[C@H](C[C@]1([H])[C@H]2C(C)NC(=O)c1ccc(Cl)cc1)c1ccnc2ccc(F)cc12 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vivo inhibition of IDO1 in tumor of po dosed NSG mouse xenografted with human SKOV3 cells assessed as reduction in KYN level administered as singl...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00679 BindingDB Entry DOI: 10.7270/Q2RJ4P9S
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50529361 (CHEMBL4515137 | US10988487, Example 52) Show SMILES OCCNC(=O)CNc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O |r| Show InChI InChI=1S/C15H17FN6O4/c16-9-2-1-8-5-11(10(8)6-9)19-15(20-25)13-14(22-26-21-13)18-7-12(24)17-3-4-23/h1-2,6,11,23,25H,3-5,7H2,(H,17,24)(H,18,22)(H,19,20)/t11-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 preincubated for 30 mins followed by substrate tryptophan addition and measured after 60 mins by fluorescence based assay				ACS Med Chem Lett 10: 1530-1536 (2019) Article DOI: 10.1021/acsmedchemlett.9b00344 BindingDB Entry DOI: 10.7270/Q22B92G6
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50391365 (CHEMBL2147990) Show SMILES N#Cc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C9H6N4/c10-5-7-2-1-3-8(4-7)9-6-11-13-12-9/h1-4,6H,(H,11,12,13)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50391372 (CHEMBL2147992) Show SMILES CCc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C10H11N3/c1-2-8-4-3-5-9(6-8)10-7-11-13-12-10/h3-7H,2H2,1H3,(H,11,12,13)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571891 (CHEMBL4849714) Show SMILES [H][C@@]1(CC[C@@H](CC1)c1cncc(OC)c1)[C@@H](CC)NC(=O)c1ccc(Cl)cc1 |r,wU:15.17,wD:4.7,1.0,(27.52,-17.21,;27.93,-18.7,;27.93,-20.24,;26.61,-21.01,;25.28,-20.24,;25.28,-18.7,;26.61,-17.93,;23.94,-21.02,;22.61,-20.24,;21.27,-21.02,;21.27,-22.56,;22.62,-23.32,;22.63,-24.85,;21.31,-25.63,;23.95,-22.55,;29.27,-17.94,;29.27,-16.4,;30.6,-15.63,;30.6,-18.71,;30.6,-20.25,;29.26,-21.02,;31.93,-21.03,;31.92,-22.57,;33.25,-23.34,;34.59,-22.57,;35.92,-23.34,;34.59,-21.03,;33.26,-20.25,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559679 (CHEMBL4752094) Show SMILES CCC(Nc1nnc(o1)-c1ccc(OC)cc1)[C@H]1CC[C@H](CC1)c1ccnc2ccc(F)cc12 |wU:20.25,17.18,(1.91,-2.89,;3.24,-2.12,;4.57,-2.89,;5.91,-2.12,;7.24,-2.89,;7.58,-4.39,;9.11,-4.56,;9.73,-3.19,;8.58,-2.12,;11.22,-2.79,;11.62,-1.3,;13.1,-.91,;14.19,-2,;15.68,-1.6,;16.08,-.11,;13.8,-3.48,;12.31,-3.88,;4.57,-4.43,;5.91,-5.2,;5.91,-6.74,;4.57,-7.51,;3.24,-6.74,;3.24,-5.2,;4.57,-9.05,;3.24,-9.82,;3.24,-11.36,;4.58,-12.13,;5.91,-11.36,;7.25,-12.12,;8.57,-11.35,;8.56,-9.82,;9.89,-9.05,;7.23,-9.06,;5.91,-9.82,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50355861 (CHEMBL1909733) Show SMILES Brc1ccccc1-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-4-2-1-3-6(7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559677 (CHEMBL4746203) Show SMILES CCC(Nc1nnc(o1)-c1ccc(OC)cc1)[C@H]1CC[C@H](CC1)c1ccnc2c(F)cc(F)cc12 |r,wU:20.25,17.18,(3.44,-6.79,;4.77,-6.02,;6.11,-6.79,;7.45,-6.02,;8.78,-6.79,;9.11,-8.29,;10.65,-8.46,;11.27,-7.08,;10.11,-6.02,;12.76,-6.68,;13.16,-5.2,;14.65,-4.8,;15.74,-5.89,;17.22,-5.49,;17.62,-4,;15.34,-7.37,;13.86,-7.78,;6.11,-8.33,;7.45,-9.1,;7.45,-10.65,;6.11,-11.42,;4.77,-10.65,;4.77,-9.1,;6.11,-12.96,;4.78,-13.73,;4.78,-15.27,;6.12,-16.05,;7.44,-15.27,;8.78,-16.03,;8.79,-17.57,;10.1,-15.25,;10.1,-13.72,;11.43,-12.96,;8.76,-12.96,;7.45,-13.73,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559673 (CHEMBL4779097) Show SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)c1nc2ncc(Cl)cc2[nH]1 |r,wU:4.7,18.21,wD:1.0,(4.37,-8.37,;5.88,-8.63,;4.55,-9.4,;4.55,-10.95,;5.88,-11.71,;7.22,-10.95,;7.22,-9.4,;5.88,-13.27,;4.54,-14.04,;4.54,-15.57,;5.89,-16.35,;7.21,-15.57,;8.54,-16.35,;9.88,-15.58,;9.88,-14.03,;11.22,-13.25,;8.54,-13.26,;7.22,-14.03,;5.88,-7.08,;4.55,-6.31,;7.22,-6.31,;7.21,-4.77,;8.68,-4.29,;9.31,-2.88,;10.83,-2.72,;11.74,-3.96,;13.28,-3.79,;11.11,-5.37,;9.58,-5.54,;8.68,-6.78,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50549536 (CHEMBL4751227) Show SMILES CC[C@H](N1CCC2(COc3cc(ccc23)C(F)(F)F)CC1)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse IDO1 expressed in HEK cells				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127738 BindingDB Entry DOI: 10.7270/Q270851B
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50571888 (CHEMBL4847982) Show SMILES [H][C@@]1(CC[C@@H](CC1)c1cccc(n1)C(F)(F)F)[C@@H](CC)NC(=O)c1ccc(Cl)cc1 |r,wU:4.7,17.19,1.0,(8.43,-31.44,;8.83,-32.93,;7.51,-32.15,;6.18,-32.93,;6.18,-34.47,;7.51,-35.23,;8.83,-34.47,;4.85,-35.25,;3.51,-34.47,;2.18,-35.24,;2.18,-36.79,;3.53,-37.55,;4.85,-36.77,;3.53,-39.08,;5.06,-39.08,;4.3,-40.4,;2.21,-39.85,;10.17,-32.16,;10.18,-30.62,;11.51,-29.86,;11.51,-32.94,;11.5,-34.48,;10.16,-35.25,;12.83,-35.25,;12.82,-36.79,;14.15,-37.56,;15.49,-36.8,;16.83,-37.57,;15.49,-35.25,;14.16,-34.48,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00236 BindingDB Entry DOI: 10.7270/Q2KS6W9W
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50559675 (CHEMBL4796040) Show SMILES COCC(Nc1nnc(o1)-c1ccc(OC)cc1)[C@H]1CC[C@H](CC1)c1ccnc2ccc(F)cc12 |r,wU:21.26,18.19,(3.5,-4.34,;4.84,-5.11,;6.17,-4.33,;7.51,-5.11,;8.85,-4.33,;10.18,-5.11,;10.51,-6.6,;12.05,-6.78,;12.67,-5.4,;11.52,-4.33,;14.17,-5,;14.57,-3.51,;16.05,-3.12,;17.15,-4.2,;18.63,-3.8,;19.03,-2.31,;16.74,-5.69,;15.26,-6.1,;7.51,-6.64,;8.85,-7.42,;8.85,-8.96,;7.51,-9.73,;6.17,-8.96,;6.17,-7.42,;7.51,-11.28,;6.18,-12.05,;6.18,-13.58,;7.52,-14.36,;8.85,-13.58,;10.18,-14.35,;11.5,-13.57,;11.5,-12.04,;12.83,-11.26,;10.17,-11.28,;8.85,-12.04,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IDO1 in recombinant IFN-gamma induced mouse M109 cells incubated for 18 hrs by fluorescence microplate reader assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00014 BindingDB Entry DOI: 10.7270/Q24Q7ZP9
					More data for this Ligand-Target Pair

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