Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544215 (CHEMBL4637689) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544211 (CHEMBL4641682) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0870 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544227 (CHEMBL4634501) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50286578 (CHEMBL4170617) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system after 30 mins by fluoresc... | ACS Med Chem Lett 9: 34-38 (2018) Article DOI: 10.1021/acsmedchemlett.7b00414 BindingDB Entry DOI: 10.7270/Q2CZ39PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544217 (CHEMBL4644307) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544213 (CHEMBL4647458) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544212 (CHEMBL4632775) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544223 (CHEMBL4637836) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50286560 (CHEMBL4163681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system after 30 mins by fluoresc... | ACS Med Chem Lett 9: 34-38 (2018) Article DOI: 10.1021/acsmedchemlett.7b00414 BindingDB Entry DOI: 10.7270/Q2CZ39PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system after 30 mins by fluoresc... | ACS Med Chem Lett 9: 34-38 (2018) Article DOI: 10.1021/acsmedchemlett.7b00414 BindingDB Entry DOI: 10.7270/Q2CZ39PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437809 (CHEMBL2407717) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437812 (CHEMBL2407723) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544226 (CHEMBL4632449) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437821 (CHEMBL2407736) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544225 (CHEMBL4641904) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437816 (CHEMBL2407719) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50361170 (CHEMBL4159366) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 (397 to 503 residues) co-expressed in insect cells using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate ... | J Med Chem 61: 6056-6074 (2018) Article DOI: 10.1021/acs.jmedchem.8b00393 BindingDB Entry DOI: 10.7270/Q2RN3BDN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544224 (CHEMBL4644721) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544228 (CHEMBL4647164) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437813 (CHEMBL2407722) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437822 (CHEMBL2407735) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437827 (CHEMBL2407730) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437814 (CHEMBL2407721) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437826 (CHEMBL2407731) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50361177 (CHEMBL4160840) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 (397 to 503 residues) co-expressed in insect cells using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate ... | J Med Chem 61: 6056-6074 (2018) Article DOI: 10.1021/acs.jmedchem.8b00393 BindingDB Entry DOI: 10.7270/Q2RN3BDN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544214 (CHEMBL4633968) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST tagged NCOR1 (397 to 503 residues) expressed in insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate prei... | J Med Chem 60: 7965-7983 (2017) Article DOI: 10.1021/acs.jmedchem.7b00467 BindingDB Entry DOI: 10.7270/Q2VM4FDV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437815 (CHEMBL2407720) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human GST-fused HDAC3/NCOR1 (397 to 503 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-A... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112648 BindingDB Entry DOI: 10.7270/Q2Z323DQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437818 (CHEMBL2407716) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437825 (CHEMBL2407732) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437817 (CHEMBL2407718) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50565547 (CHEMBL4781177) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human GST-fused HDAC3/NCOR1 (397 to 503 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-A... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112648 BindingDB Entry DOI: 10.7270/Q2Z323DQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437823 (CHEMBL2407734) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544221 (CHEMBL4639586) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437824 (CHEMBL2407733) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50565548 (CHEMBL4790998) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 106 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human GST-fused HDAC3/NCOR1 (397 to 503 residues) expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-A... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112648 BindingDB Entry DOI: 10.7270/Q2Z323DQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50437833 (CHEMBL2407742) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC3-NCoR1 (unknown origin) using MAL as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins ... | J Med Chem 56: 6156-74 (2013) Article DOI: 10.1021/jm400634n BindingDB Entry DOI: 10.7270/Q2N87C65 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544222 (CHEMBL4646763) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50525180 (CHEMBL4446236) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b... | Eur J Med Chem 176: 195-207 (2019) Article DOI: 10.1016/j.ejmech.2019.05.007 BindingDB Entry DOI: 10.7270/Q2NG4V23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544218 (CHEMBL4636534) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50525179 (CHEMBL4450474) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 215 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b... | Eur J Med Chem 176: 195-207 (2019) Article DOI: 10.1016/j.ejmech.2019.05.007 BindingDB Entry DOI: 10.7270/Q2NG4V23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50544219 (CHEMBL4644575) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co. Curated by ChEMBL | Assay Description Inhibition of full length human recombinant FLAG-tagged HDAC3/His6-tagged SMRT (1 to 899 residues) expressed in HEK293F cells using FLUOR DE LYS as s... | ACS Med Chem Lett 11: 1476-1483 (2020) Article DOI: 10.1021/acsmedchemlett.0c00302 BindingDB Entry DOI: 10.7270/Q2RV0S85 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50242817 (CHEMBL4087968) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 234 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b... | Eur J Med Chem 176: 195-207 (2019) Article DOI: 10.1016/j.ejmech.2019.05.007 BindingDB Entry DOI: 10.7270/Q2NG4V23 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50361171 (CHEMBL4175555) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 234 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 (397 to 503 residues) co-expressed in insect cells using (Ac-Leu-Gly-Lys(Ac)-AMC as substrate ... | J Med Chem 61: 6056-6074 (2018) Article DOI: 10.1021/acs.jmedchem.8b00393 BindingDB Entry DOI: 10.7270/Q2RN3BDN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50121210 (CHEMBL3622374) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of recombinant human HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system using Fluor de Lys as sub... | J Med Chem 62: 9375-9414 (2019) Article DOI: 10.1021/acs.jmedchem.9b00359 BindingDB Entry DOI: 10.7270/Q2BR8WFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50121210 (CHEMBL3622374) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system by fluorescence assay | Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077 BindingDB Entry DOI: 10.7270/Q2K93BZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50121211 (CHEMBL3622375) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of recombinant human HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system using Fluor de Lys as sub... | J Med Chem 62: 9375-9414 (2019) Article DOI: 10.1021/acs.jmedchem.9b00359 BindingDB Entry DOI: 10.7270/Q2BR8WFX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50121211 (CHEMBL3622375) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Jadavpur University Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3/GST-tagged NCOR1 DAD (397 to 503 residues) expressed in baculovirus expression system by fluorescence assay | Eur J Med Chem 166: 369-380 (2019) Article DOI: 10.1016/j.ejmech.2019.01.077 BindingDB Entry DOI: 10.7270/Q2K93BZT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor corepressor 1 (Homo sapiens (Human)) | BDBM50525178 (CHEMBL4437852) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 274 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b... | Eur J Med Chem 176: 195-207 (2019) Article DOI: 10.1016/j.ejmech.2019.05.007 BindingDB Entry DOI: 10.7270/Q2NG4V23 | |||||||||||
More data for this Ligand-Target Pair |
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