Compile Data Set for Download or QSAR

Found 1125 hits of ic50 for UniProtKB: Q9Y4K0   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505633 (CHEMBL4448713) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O Show InChI InChI=1S/C22H26FN3O4S2/c1-15-22(16-6-5-7-19(12-16)32(29,30)25(2)3)20-13-18(31(4,27)28)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505638 (CHEMBL4457578) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505638 (CHEMBL4457578) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505638 (CHEMBL4457578) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of LOXL2 in human IMR90 cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measur...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505640 (CHEMBL4556859) Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(Cc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H20FN5O2S/c1-20(2)24(22,23)15-5-3-12(4-6-15)9-14-11-21(19-18-14)10-13(16)7-8-17/h3-7,11H,8-10,17H2,1-2H3/b13-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505638 (CHEMBL4457578) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells assessed as inhibition of collagen oxid...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505638 (CHEMBL4457578) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human LOXL2 assessed as inhibition of collagen cross linking compound replenishment for 5 days and measured on day 7 by UPL...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505658 (CHEMBL4581458) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cccnc12 Show InChI InChI=1S/C20H23FN4O2S/c1-14-19(15-6-4-7-17(12-15)28(26,27)24(2)3)20-18(8-5-11-23-20)25(14)13-16(21)9-10-22/h4-9,11-12H,10,13,22H2,1-3H3/b16-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505647 (CHEMBL4531065) Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)c(Cl)c1 Show InChI InChI=1S/C15H19ClFN5O3S/c1-21(2)26(23,24)13-3-4-15(14(16)7-13)25-10-12-9-22(20-19-12)8-11(17)5-6-18/h3-5,7,9H,6,8,10,18H2,1-2H3/b11-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505653 (CHEMBL4458907) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(NS(C)(=O)=O)cc12 Show InChI InChI=1S/C22H27FN4O4S2/c1-15-22(16-6-5-7-19(12-16)33(30,31)26(2)3)20-13-18(25-32(4,28)29)8-9-21(20)27(15)14-17(23)10-11-24/h5-10,12-13,25H,11,14,24H2,1-4H3/b17-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505657 (CHEMBL4467234) Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(NCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H21FN6O2S/c1-21(2)25(23,24)15-5-3-13(4-6-15)18-9-14-11-22(20-19-14)10-12(16)7-8-17/h3-7,11,18H,8-10,17H2,1-2H3/b12-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505643 (CHEMBL4582216) Show SMILES Cl.CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 Show InChI InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526723 (CHEMBL4515085 | US10807974, Example 121 | US109950...) Show SMILES Cc1ccc(cc1)-c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)S(C)(=O)=O Show InChI InChI=1S/C18H18N2O4S3/c1-12-3-5-13(6-4-12)14-7-15(26(2,21)22)9-16(8-14)27(23,24)18-11-20-17(10-19)25-18/h3-9,11H,10,19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526723 (CHEMBL4515085 | US10807974, Example 121 | US109950...) Show SMILES Cc1ccc(cc1)-c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)S(C)(=O)=O Show InChI InChI=1S/C18H18N2O4S3/c1-12-3-5-13(6-4-12)14-7-15(26(2,21)22)9-16(8-14)27(23,24)18-11-20-17(10-19)25-18/h3-9,11H,10,19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526723 (CHEMBL4515085 | US10807974, Example 121 | US109950...) Show SMILES Cc1ccc(cc1)-c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)S(C)(=O)=O Show InChI InChI=1S/C18H18N2O4S3/c1-12-3-5-13(6-4-12)14-7-15(26(2,21)22)9-16(8-14)27(23,24)18-11-20-17(10-19)25-18/h3-9,11H,10,19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266796 (CHEMBL4068580) Show SMILES Cl.NCc1cc(Oc2cccc(c2)C(=O)NCc2cc3ccccc3s2)nc(c1)C(F)(F)F Show InChI InChI=1S/C23H18F3N3O2S/c24-23(25,26)20-8-14(12-27)9-21(29-20)31-17-6-3-5-16(10-17)22(30)28-13-18-11-15-4-1-2-7-19(15)32-18/h1-11H,12-13,27H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266838 (CHEMBL4084982) Show SMILES Cl.NCc1cc(Oc2cccc(c2)C(=O)NCCS(N)(=O)=O)nc(c1)C(F)(F)F Show InChI InChI=1S/C16H17F3N4O4S/c17-16(18,19)13-6-10(9-20)7-14(23-13)27-12-3-1-2-11(8-12)15(24)22-4-5-28(21,25)26/h1-3,6-8H,4-5,9,20H2,(H,22,24)(H2,21,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266824 (CHEMBL4082808) Show SMILES Cl.NCc1cc(Oc2cccc(c2)C(=O)NCCn2cnnn2)nc(c1)C(F)(F)F Show InChI InChI=1S/C17H16F3N7O2/c18-17(19,20)14-6-11(9-21)7-15(24-14)29-13-3-1-2-12(8-13)16(28)22-4-5-27-10-23-25-26-27/h1-3,6-8,10H,4-5,9,21H2,(H,22,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469087 (US10807974, Example 106 | US10995088, Example 106 ...) Show SMILES CCc1cc(CC)cc(c1)S(=O)(=O)c1cnc(CN)s1 Show InChI InChI=1S/C14H18N2O2S2/c1-3-10-5-11(4-2)7-12(6-10)20(17,18)14-9-16-13(8-15)19-14/h5-7,9H,3-4,8,15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469087 (US10807974, Example 106 | US10995088, Example 106 ...) Show SMILES CCc1cc(CC)cc(c1)S(=O)(=O)c1cnc(CN)s1 Show InChI InChI=1S/C14H18N2O2S2/c1-3-10-5-11(4-2)7-12(6-10)20(17,18)14-9-16-13(8-15)19-14/h5-7,9H,3-4,8,15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469087 (US10807974, Example 106 | US10995088, Example 106 ...) Show SMILES CCc1cc(CC)cc(c1)S(=O)(=O)c1cnc(CN)s1 Show InChI InChI=1S/C14H18N2O2S2/c1-3-10-5-11(4-2)7-12(6-10)20(17,18)14-9-16-13(8-15)19-14/h5-7,9H,3-4,8,15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266783 (CHEMBL4086010) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)Nc2ccc(F)cc2)c1 Show InChI InChI=1S/C19H16FN3O2/c20-15-4-6-16(7-5-15)23-19(24)14-2-1-3-17(11-14)25-18-10-13(12-21)8-9-22-18/h1-11H,12,21H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505645 (CHEMBL4550754) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(O)cc12 Show InChI InChI=1S/C21H24FN3O3S/c1-14-21(15-5-4-6-18(11-15)29(27,28)24(2)3)19-12-17(26)7-8-20(19)25(14)13-16(22)9-10-23/h4-9,11-12,26H,10,13,23H2,1-3H3/b16-9-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505634 (CHEMBL4569453) Show SMILES Cl.CN(C)S(=O)(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)cc1 Show InChI InChI=1S/C15H20FN5O3S/c1-20(2)25(22,23)15-5-3-14(4-6-15)24-11-13-10-21(19-18-13)9-12(16)7-8-17/h3-7,10H,8-9,11,17H2,1-2H3/b12-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266784 (CHEMBL4103928) Show SMILES Cl.COc1ccc(NC(=O)c2cccc(Oc3cc(CN)ccn3)c2)cc1 Show InChI InChI=1S/C20H19N3O3/c1-25-17-7-5-16(6-8-17)23-20(24)15-3-2-4-18(12-15)26-19-11-14(13-21)9-10-22-19/h2-12H,13,21H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469088 (US10807974, Example 107 | US10995088, Example 107 ...) Show SMILES CCc1cccc(c1)S(=O)(=O)c1cnc(CN)s1 Show InChI InChI=1S/C12H14N2O2S2/c1-2-9-4-3-5-10(6-9)18(15,16)12-8-14-11(7-13)17-12/h3-6,8H,2,7,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469088 (US10807974, Example 107 | US10995088, Example 107 ...) Show SMILES CCc1cccc(c1)S(=O)(=O)c1cnc(CN)s1 Show InChI InChI=1S/C12H14N2O2S2/c1-2-9-4-3-5-10(6-9)18(15,16)12-8-14-11(7-13)17-12/h3-6,8H,2,7,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469088 (US10807974, Example 107 | US10995088, Example 107 ...) Show SMILES CCc1cccc(c1)S(=O)(=O)c1cnc(CN)s1 Show InChI InChI=1S/C12H14N2O2S2/c1-2-9-4-3-5-10(6-9)18(15,16)12-8-14-11(7-13)17-12/h3-6,8H,2,7,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266789 (CHEMBL4088453) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)Nc2ccccc2)c1 Show InChI InChI=1S/C19H17N3O2/c20-13-14-9-10-21-18(11-14)24-17-8-4-5-15(12-17)19(23)22-16-6-2-1-3-7-16/h1-12H,13,20H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469029 (US10807974, Example 14 | US10807974, Example 42 | ...) Show SMILES NCc1ccc(s1)S(=O)(=O)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C15H18N2O4S3/c16-11-12-6-7-15(22-12)23(18,19)13-4-3-5-14(10-13)24(20,21)17-8-1-2-9-17/h3-7,10H,1-2,8-9,11,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526725 (CHEMBL4450748 | US10807974, Example 122 | US109950...) Show SMILES CNc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C17H17N3O2S2/c1-19-14-7-13(12-5-3-2-4-6-12)8-15(9-14)24(21,22)17-11-20-16(10-18)23-17/h2-9,11,19H,10,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526725 (CHEMBL4450748 | US10807974, Example 122 | US109950...) Show SMILES CNc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C17H17N3O2S2/c1-19-14-7-13(12-5-3-2-4-6-12)8-15(9-14)24(21,22)17-11-20-16(10-18)23-17/h2-9,11,19H,10,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526725 (CHEMBL4450748 | US10807974, Example 122 | US109950...) Show SMILES CNc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C17H17N3O2S2/c1-19-14-7-13(12-5-3-2-4-6-12)8-15(9-14)24(21,22)17-11-20-16(10-18)23-17/h2-9,11,19H,10,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266823 (CHEMBL4097435) Show SMILES Cl.Cl.NCc1cc(Oc2cccc(c2)C(=O)N2CC[C@@H](N)C2)nc(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H19F3N4O2.2ClH/c19-18(20,21)15-6-11(9-22)7-16(24-15)27-14-3-1-2-12(8-14)17(26)25-5-4-13(23)10-25;;/h1-3,6-8,13H,4-5,9-10,22-23H2;2*1H/t13-;;/m1../s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526740 (CHEMBL4447452 | US10807974, Example 108 | US109950...) Show SMILES NCc1ncc(s1)S(=O)(=O)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O2S2/c17-10-15-18-11-16(21-15)22(19,20)14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-9,11H,10,17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526740 (CHEMBL4447452 | US10807974, Example 108 | US109950...) Show SMILES NCc1ncc(s1)S(=O)(=O)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O2S2/c17-10-15-18-11-16(21-15)22(19,20)14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-9,11H,10,17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526740 (CHEMBL4447452 | US10807974, Example 108 | US109950...) Show SMILES NCc1ncc(s1)S(=O)(=O)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C16H14N2O2S2/c17-10-15-18-11-16(21-15)22(19,20)14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-9,11H,10,17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266788 (CHEMBL4067192) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)NCc2ccccc2)c1 Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-10-22-19(11-16)25-18-8-4-7-17(12-18)20(24)23-14-15-5-2-1-3-6-15/h1-12H,13-14,21H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266811 (CHEMBL4059919) Show SMILES Cl.NCc1cc(Oc2cccc(c2)C(=O)Nc2ccccc2)nc(c1)C(F)(F)F Show InChI InChI=1S/C20H16F3N3O2/c21-20(22,23)17-9-13(12-24)10-18(26-17)28-16-8-4-5-14(11-16)19(27)25-15-6-2-1-3-7-15/h1-11H,12,24H2,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266811 (CHEMBL4059919) Show SMILES Cl.NCc1cc(Oc2cccc(c2)C(=O)Nc2ccccc2)nc(c1)C(F)(F)F Show InChI InChI=1S/C20H16F3N3O2/c21-20(22,23)17-9-13(12-24)10-18(26-17)28-16-8-4-5-14(11-16)19(27)25-15-6-2-1-3-7-15/h1-11H,12,24H2,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266788 (CHEMBL4067192) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)NCc2ccccc2)c1 Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-10-22-19(11-16)25-18-8-4-7-17(12-18)20(24)23-14-15-5-2-1-3-6-15/h1-12H,13-14,21H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266838 (CHEMBL4084982) Show SMILES Cl.NCc1cc(Oc2cccc(c2)C(=O)NCCS(N)(=O)=O)nc(c1)C(F)(F)F Show InChI InChI=1S/C16H17F3N4O4S/c17-16(18,19)13-6-10(9-20)7-14(23-13)27-12-3-1-2-11(8-12)15(24)22-4-5-28(21,25)26/h1-3,6-8H,4-5,9,20H2,(H,22,24)(H2,21,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50505661 (CHEMBL4574820) Show SMILES Cl.CN(C)C(=O)c1ccc2c(c(C)n(C\C(F)=C\CN)c2c1)-c1cccc(c1)S(=O)(=O)N(C)C Show InChI InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-10-9-18(24(30)27(2)3)14-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469139 (US10807974, Example 158 | US10995088, Example 158 ...) Show SMILES Cc1ccc(cn1)-c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)C(O)=O Show InChI InChI=1S/C17H15N3O4S2/c1-10-2-3-11(8-19-10)12-4-13(17(21)22)6-14(5-12)26(23,24)16-9-20-15(7-18)25-16/h2-6,8-9H,7,18H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 1 hour at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469139 (US10807974, Example 158 | US10995088, Example 158 ...) Show SMILES Cc1ccc(cn1)-c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)C(O)=O Show InChI InChI=1S/C17H15N3O4S2/c1-10-2-3-11(8-19-10)12-4-13(17(21)22)6-14(5-12)26(23,24)16-9-20-15(7-18)25-16/h2-6,8-9H,7,18H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 1 hr at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021) BindingDB Entry DOI: 10.7270/Q2125WSK
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM469139 (US10807974, Example 158 | US10995088, Example 158 ...) Show SMILES Cc1ccc(cn1)-c1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)C(O)=O Show InChI InChI=1S/C17H15N3O4S2/c1-10-2-3-11(8-19-10)12-4-13(17(21)22)6-14(5-12)26(23,24)16-9-20-15(7-18)25-16/h2-6,8-9H,7,18H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526731 (CHEMBL4564074 | US10807974, Example 103 | US109950...) Show SMILES CCc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C18H18N2O2S2/c1-2-13-8-15(14-6-4-3-5-7-14)10-16(9-13)24(21,22)18-12-20-17(11-19)23-18/h3-10,12H,2,11,19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526731 (CHEMBL4564074 | US10807974, Example 103 | US109950...) Show SMILES CCc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C18H18N2O2S2/c1-2-13-8-15(14-6-4-3-5-7-14)10-16(9-13)24(21,22)18-12-20-17(11-19)23-18/h3-10,12H,2,11,19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...				Citation and Details BindingDB Entry DOI: 10.7270/Q25M69MF
					More data for this Ligand-Target Pair

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