Compile Data Set for Download or QSAR

Found 38 hits of ic50 for UniProtKB: P0A0H2   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292289 (CHEMBL4175510) Show SMILES Cc1nccc(n1)C(=O)Nc1cc(NC(=O)c2ccccc2)ccc1C Show InChI InChI=1S/C20H18N4O2/c1-13-8-9-16(23-19(25)15-6-4-3-5-7-15)12-18(13)24-20(26)17-10-11-21-14(2)22-17/h3-12H,1-2H3,(H,23,25)(H,24,26)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial ErmC' assessed as decrease in rRNA methylation preincubated for 15 mins followed by S-adenosyl-L-[methyl3H]methionine additio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291837 (CHEMBL4172068) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1c[nH]c(=O)[nH]1 Show InChI InChI=1S/C14H14F3N5O2/c15-14(16,17)9-1-2-11(18-7-9)21-3-5-22(6-4-21)12(23)10-8-19-13(24)20-10/h1-2,7-8H,3-6H2,(H2,19,20,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291836 (CHEMBL4177311) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1csc(Nc2ncccn2)n1 Show InChI InChI=1S/C18H16F3N7OS/c19-18(20,21)12-2-3-14(24-10-12)27-6-8-28(9-7-27)15(29)13-11-30-17(25-13)26-16-22-4-1-5-23-16/h1-5,10-11H,6-9H2,(H,22,23,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291838 (CHEMBL4166678) Show SMILES Cc1cccc(Nc2nc(cs2)C(=O)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)n1 Show InChI InChI=1S/C20H19F3N6OS/c1-13-3-2-4-16(25-13)27-19-26-15(12-31-19)18(30)29-9-7-28(8-10-29)17-6-5-14(11-24-17)20(21,22)23/h2-6,11-12H,7-10H2,1H3,(H,25,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291840 (CHEMBL4169170) Show SMILES Cc1ccc(Sc2cc(C)c(C#N)c(Sc3ccc(C)cc3)n2)cc1 Show InChI InChI=1S/C21H18N2S2/c1-14-4-8-17(9-5-14)24-20-12-16(3)19(13-22)21(23-20)25-18-10-6-15(2)7-11-18/h4-12H,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli ER2566 assessed as decrease in rRNA methylation using [methyl-3H]A...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291868 (CHEMBL4165804) Show SMILES Fc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccncc2)c1 Show InChI InChI=1S/C19H14FN3O2/c20-15-4-1-3-14(11-15)19(25)23-17-6-2-5-16(12-17)22-18(24)13-7-9-21-10-8-13/h1-12H,(H,22,24)(H,23,25)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291839 (CHEMBL4176350) Show SMILES COC(=O)c1sc2ccccc2c1OS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H11ClO5S2/c1-21-16(18)15-14(12-4-2-3-5-13(12)23-15)22-24(19,20)11-8-6-10(17)7-9-11/h2-9H,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli ER2566 assessed as decrease in rRNA methylation using [methyl-3H]A...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291865 (CHEMBL4172623) Show SMILES Cc1occc1C(=O)Nc1nc(CC(=O)Nc2ccccc2)cs1 Show InChI InChI=1S/C17H15N3O3S/c1-11-14(7-8-23-11)16(22)20-17-19-13(10-24-17)9-15(21)18-12-5-3-2-4-6-12/h2-8,10H,9H2,1H3,(H,18,21)(H,19,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291871 (CHEMBL4170758) Show SMILES O=C(CSc1nnc2c(n1)[nH]c1ccccc21)Nc1ccccn1 Show InChI InChI=1S/C16H12N6OS/c23-13(19-12-7-3-4-8-17-12)9-24-16-20-15-14(21-22-16)10-5-1-2-6-11(10)18-15/h1-8H,9H2,(H,17,19,23)(H,18,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292290 (CHEMBL4159457) Show SMILES O=C(Nc1nccs1)c1cc(nc2ccccc12)-c1ccccn1 Show InChI InChI=1S/C18H12N4OS/c23-17(22-18-20-9-10-24-18)13-11-16(15-7-3-4-8-19-15)21-14-6-2-1-5-12(13)14/h1-11H,(H,20,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292282 (CHEMBL4161245) Show SMILES Clc1ccccc1Cn1nnc2c(N\N=C\c3cccnc3)ncnc12 Show InChI InChI=1S/C17H13ClN8/c18-14-6-2-1-5-13(14)10-26-17-15(23-25-26)16(20-11-21-17)24-22-9-12-4-3-7-19-8-12/h1-9,11H,10H2,(H,20,21,24)/b22-9+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli ER2566 assessed as decrease in rRNA methylation using [methyl-3H]A...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292311 (CHEMBL4159029) Show SMILES O=C(NCCSc1ccccc1)c1ccc(cc1)-n1cncn1 Show InChI InChI=1S/C17H16N4OS/c22-17(19-10-11-23-16-4-2-1-3-5-16)14-6-8-15(9-7-14)21-13-18-12-20-21/h1-9,12-13H,10-11H2,(H,19,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292285 (CHEMBL4165860) Show SMILES CCCc1cc([nH]n1)C(=O)Nc1cccc(OCc2ccncc2)c1 Show InChI InChI=1S/C19H20N4O2/c1-2-4-16-12-18(23-22-16)19(24)21-15-5-3-6-17(11-15)25-13-14-7-9-20-10-8-14/h3,5-12H,2,4,13H2,1H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291835 (CHEMBL4098242) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(O)c2)n1 Show InChI InChI=1S/C15H14N4O2S2/c1-8-13(23-15(16-8)17-9(2)20)12-7-22-14(19-12)18-10-4-3-5-11(21)6-10/h3-7,21H,1-2H3,(H,18,19)(H,16,17,20)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291841 (CHEMBL4169582) Show SMILES O=C1N(CN(CCCn2ccnc2)CN2C(=O)c3ccccc3C2=O)C(=O)c2ccccc12 Show InChI InChI=1S/C24H21N5O4/c30-21-17-6-1-2-7-18(17)22(31)28(21)15-27(12-5-11-26-13-10-25-14-26)16-29-23(32)19-8-3-4-9-20(19)24(29)33/h1-4,6-10,13-14H,5,11-12,15-16H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' expressed in Escherichia coli ER2566 assessed as decrease in rRNA methylation using [methyl-3H]A...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292313 (CHEMBL4176416) Show SMILES O=C(CSc1nc2cccnc2[nH]1)Nc1nccs1 Show InChI InChI=1S/C11H9N5OS2/c17-8(15-10-13-4-5-18-10)6-19-11-14-7-2-1-3-12-9(7)16-11/h1-5H,6H2,(H,12,14,16)(H,13,15,17)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292286 (CHEMBL4176579) Show SMILES Nc1nc(N)nc(CSc2nnc(NCc3ccccc3)s2)n1 Show InChI InChI=1S/C13H14N8S2/c14-10-17-9(18-11(15)19-10)7-22-13-21-20-12(23-13)16-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,16,20)(H4,14,15,17,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292309 (CHEMBL4164668) Show SMILES FC(F)(F)c1cnc(N2CCN(CC2)C(=O)c2cc(Cl)c[nH]2)c(Cl)c1 Show InChI InChI=1S/C15H13Cl2F3N4O/c16-10-6-12(21-8-10)14(25)24-3-1-23(2-4-24)13-11(17)5-9(7-22-13)15(18,19)20/h5-8,21H,1-4H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292308 (CHEMBL4164726) Show SMILES O=C(NC1CCN(CC1)c1nc2ccccc2s1)c1ccncc1 Show InChI InChI=1S/C18H18N4OS/c23-17(13-5-9-19-10-6-13)20-14-7-11-22(12-8-14)18-21-15-3-1-2-4-16(15)24-18/h1-6,9-10,14H,7-8,11-12H2,(H,20,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292283 (CHEMBL4166273) Show SMILES Cn1cnnc1-c1cccc(NC(=O)Cc2cccc(F)c2)c1 Show InChI InChI=1S/C17H15FN4O/c1-22-11-19-21-17(22)13-5-3-7-15(10-13)20-16(23)9-12-4-2-6-14(18)8-12/h2-8,10-11H,9H2,1H3,(H,20,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292310 (CHEMBL4163790) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(Cc2c[nH]c(n2)-c2ccccc2)CC1 Show InChI InChI=1S/C20H20F3N5/c21-20(22,23)16-6-7-18(24-12-16)28-10-8-27(9-11-28)14-17-13-25-19(26-17)15-4-2-1-3-5-15/h1-7,12-13H,8-11,14H2,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292284 (CHEMBL4165307) Show SMILES O=C(NCCOc1ccc2OCOc2c1)c1ccc2ccccc2n1 Show InChI InChI=1S/C19H16N2O4/c22-19(16-7-5-13-3-1-2-4-15(13)21-16)20-9-10-23-14-6-8-17-18(11-14)25-12-24-17/h1-8,11H,9-10,12H2,(H,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291873 (CHEMBL4169684) Show SMILES O=C(NCc1cccc(Cn2ccnc2)c1)c1cc2ccccc2o1 Show InChI InChI=1S/C20H17N3O2/c24-20(19-11-17-6-1-2-7-18(17)25-19)22-12-15-4-3-5-16(10-15)13-23-9-8-21-14-23/h1-11,14H,12-13H2,(H,22,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292314 (CHEMBL4176470) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCc1ccncc1 Show InChI InChI=1S/C15H17N3O3S/c1-12(19)18-14-2-4-15(5-3-14)22(20,21)17-11-8-13-6-9-16-10-7-13/h2-7,9-10,17H,8,11H2,1H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50292312 (CHEMBL4170092) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(Cc2cn3ccccc3n2)CC1 Show InChI InChI=1S/C18H18F3N5/c19-18(20,21)14-4-5-16(22-11-14)25-9-7-24(8-10-25)12-15-13-26-6-2-1-3-17(26)23-15/h1-6,11,13H,7-10,12H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as decrease in rRNA methylatio...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291870 (CHEMBL4162356) Show SMILES COc1ccc(cc1)C(=O)CSc1nc(O)cc(=O)[nH]1 Show InChI InChI=1S/C13H12N2O4S/c1-19-9-4-2-8(3-5-9)10(16)7-20-13-14-11(17)6-12(18)15-13/h2-6H,7H2,1H3,(H2,14,15,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291869 (CHEMBL4173033) Show SMILES CN(C)c1ccc(CNC(=O)c2ccc(cc2)-n2cncn2)cc1 Show InChI InChI=1S/C18H19N5O/c1-22(2)16-7-3-14(4-8-16)11-20-18(24)15-5-9-17(10-6-15)23-13-19-12-21-23/h3-10,12-13H,11H2,1-2H3,(H,20,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291867 (CHEMBL4169237) Show SMILES O=C(Cc1cn2ccsc2n1)Nc1cccc(c1)N1CCCC1=O Show InChI InChI=1S/C17H16N4O2S/c22-15(10-13-11-20-7-8-24-17(20)19-13)18-12-3-1-4-14(9-12)21-6-2-5-16(21)23/h1,3-4,7-9,11H,2,5-6,10H2,(H,18,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291866 (CHEMBL4161309) Show SMILES Fc1cccc(CC(=O)Nc2cccc(c2)-c2ccn[nH]2)c1 Show InChI InChI=1S/C17H14FN3O/c18-14-5-1-3-12(9-14)10-17(22)20-15-6-2-4-13(11-15)16-7-8-19-21-16/h1-9,11H,10H2,(H,19,21)(H,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291864 (CHEMBL4176016) Show SMILES Fc1ccc(OCn2ccc(n2)C(=O)Nc2ccncc2)cc1Cl Show InChI InChI=1S/C16H12ClFN4O2/c17-13-9-12(1-2-14(13)18)24-10-22-8-5-15(21-22)16(23)20-11-3-6-19-7-4-11/h1-9H,10H2,(H,19,20,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291863 (CHEMBL4168166) Show SMILES Fc1ccc(NC(=O)Nc2ccn(CCc3ccncc3)n2)c(F)c1 Show InChI InChI=1S/C17H15F2N5O/c18-13-1-2-15(14(19)11-13)21-17(25)22-16-6-10-24(23-16)9-5-12-3-7-20-8-4-12/h1-4,6-8,10-11H,5,9H2,(H2,21,22,23,25)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291862 (CHEMBL4162820) Show SMILES Clc1ccccc1C(=O)Nc1cccc(NCc2ccncc2)c1 Show InChI InChI=1S/C19H16ClN3O/c20-18-7-2-1-6-17(18)19(24)23-16-5-3-4-15(12-16)22-13-14-8-10-21-11-9-14/h1-12,22H,13H2,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291861 (CHEMBL4172416) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1cc(n[nH]1)C1CC1 Show InChI InChI=1S/C17H18F3N5O/c18-17(19,20)12-3-4-15(21-10-12)24-5-7-25(8-6-24)16(26)14-9-13(22-23-14)11-1-2-11/h3-4,9-11H,1-2,5-8H2,(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291860 (CHEMBL4161776) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1cnn[nH]1 Show InChI InChI=1S/C13H13F3N6O/c14-13(15,16)9-1-2-11(17-7-9)21-3-5-22(6-4-21)12(23)10-8-18-20-19-10/h1-2,7-8H,3-6H2,(H,18,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291845 (CHEMBL4169047) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1cn(nn1)-c1ccccc1 Show InChI InChI=1S/C19H17F3N6O/c20-19(21,22)14-6-7-17(23-12-14)26-8-10-27(11-9-26)18(29)16-13-28(25-24-16)15-4-2-1-3-5-15/h1-7,12-13H,8-11H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291844 (CHEMBL4176909) Show SMILES FC(F)(F)c1ccc(nc1)N1CCN(CC1)C(=O)c1n[nH]c(=O)[nH]1 Show InChI InChI=1S/C13H13F3N6O2/c14-13(15,16)8-1-2-9(17-7-8)21-3-5-22(6-4-21)11(23)10-18-12(24)20-19-10/h1-2,7H,3-6H2,(H2,18,19,20,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291843 (CHEMBL4173546) Show SMILES CC(=O)c1c[nH]c(c1)C(=O)N1CCN(CC1)c1ccc(cn1)C(F)(F)F Show InChI InChI=1S/C17H17F3N4O2/c1-11(25)12-8-14(21-9-12)16(26)24-6-4-23(5-7-24)15-3-2-13(10-22-15)17(18,19)20/h2-3,8-10,21H,4-7H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair
rRNA adenine N-6-methyltransferase (Staphylococcus aureus (strain N315))	BDBM50291872 (CHEMBL2273057) Show SMILES Nn1c(SCc2nc3ccccc3[nH]2)nnc1-c1ccncc1 Show InChI InChI=1S/C15H13N7S/c16-22-14(10-5-7-17-8-6-10)20-21-15(22)23-9-13-18-11-3-1-2-4-12(11)19-13/h1-8H,9,16H2,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
International Institute of Molecular and Cell Biology Curated by ChEMBL					Assay Description Non-competitive inhibition of bacterial C-terminal His6-tagged ErmC' (unknown origin) expressed in Escherichia coli BL21(DE3) in presence of [methyl-...				Eur J Med Chem 146: 60-67 (2018) Article DOI: 10.1016/j.ejmech.2017.11.032 BindingDB Entry DOI: 10.7270/Q2P55R2F
					More data for this Ligand-Target Pair