Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50463770 (CHEMBL4238919) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase activity | Bioorg Med Chem Lett 28: 2998-3003 (2018) Article DOI: 10.1016/j.bmcl.2018.05.049 BindingDB Entry DOI: 10.7270/Q2G73HD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50463771 (CHEMBL4250651) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase activity | Bioorg Med Chem Lett 28: 2998-3003 (2018) Article DOI: 10.1016/j.bmcl.2018.05.049 BindingDB Entry DOI: 10.7270/Q2G73HD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase ATPase activity | Bioorg Med Chem Lett 28: 2998-3003 (2018) Article DOI: 10.1016/j.bmcl.2018.05.049 BindingDB Entry DOI: 10.7270/Q2G73HD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50463770 (CHEMBL4238919) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase ATPase activity | Bioorg Med Chem Lett 28: 2998-3003 (2018) Article DOI: 10.1016/j.bmcl.2018.05.049 BindingDB Entry DOI: 10.7270/Q2G73HD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50463771 (CHEMBL4250651) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase ATPase activity | Bioorg Med Chem Lett 28: 2998-3003 (2018) Article DOI: 10.1016/j.bmcl.2018.05.049 BindingDB Entry DOI: 10.7270/Q2G73HD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase activity | Bioorg Med Chem Lett 28: 2998-3003 (2018) Article DOI: 10.1016/j.bmcl.2018.05.049 BindingDB Entry DOI: 10.7270/Q2G73HD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500052 (CHEMBL3740531) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500046 (CHEMBL3742062) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500050 (CHEMBL3741396) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50606698 (CHEMBL5220158) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114454 BindingDB Entry DOI: 10.7270/Q2377DTB | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50608669 (CHEMBL3884935) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500045 (CHEMBL3741294) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50608671 (CHEMBL3883383) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500038 (CHEMBL3740159) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50608670 (CHEMBL3883797) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500054 (CHEMBL3742364) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500041 (CHEMBL3740954) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500049 (CHEMBL3741497) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500039 (CHEMBL3740857) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500048 (CHEMBL3739454) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500037 (CHEMBL3741477) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50605628 (CHEMBL5189511) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00266 BindingDB Entry DOI: 10.7270/Q2C251HR | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50605623 (CHEMBL5203837) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00266 BindingDB Entry DOI: 10.7270/Q2C251HR | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500055 (CHEMBL3740743) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50366824 (Avelox | MOXIFLOXACIN | Moxifl-oxacin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris Diderot Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrB assessed as reduction of enzyme supercoiling activity using relaxed pBR322 DNA substrat... | Bioorg Med Chem 21: 948-56 (2013) Article DOI: 10.1016/j.bmc.2012.12.011 BindingDB Entry DOI: 10.7270/Q2FF3W92 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500632 (CHEMBL3752152) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500643 (CHEMBL3752188) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50516946 (CHEMBL4549350) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical School of Nanjing University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase | Eur J Med Chem 180: 648-655 (2019) Article DOI: 10.1016/j.ejmech.2019.07.057 BindingDB Entry DOI: 10.7270/Q2639T36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50366824 (Avelox | MOXIFLOXACIN | Moxifl-oxacin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie-Paris 6 Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrB | Antimicrob Agents Chemother 52: 2909-14 (2008) Article DOI: 10.1128/AAC.01380-07 BindingDB Entry DOI: 10.7270/Q2862K8J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500641 (CHEMBL3754465) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500053 (CHEMBL3741142) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50516947 (CHEMBL4441945) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical School of Nanjing University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase | Eur J Med Chem 180: 648-655 (2019) Article DOI: 10.1016/j.ejmech.2019.07.057 BindingDB Entry DOI: 10.7270/Q2639T36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500639 (CHEMBL3754191) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500627 (CHEMBL3752277) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50117914 (1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 7.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris Diderot Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase GyrA/GyrB assessed as reduction of enzyme supercoiling activity using relaxed pBR322 DNA substrat... | Bioorg Med Chem 21: 948-56 (2013) Article DOI: 10.1016/j.bmc.2012.12.011 BindingDB Entry DOI: 10.7270/Q2FF3W92 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500619 (CHEMBL3752450) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500637 (CHEMBL3754757) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500634 (CHEMBL3754554) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500631 (CHEMBL3752620) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50516944 (CHEMBL4438262) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical School of Nanjing University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase | Eur J Med Chem 180: 648-655 (2019) Article DOI: 10.1016/j.ejmech.2019.07.057 BindingDB Entry DOI: 10.7270/Q2639T36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500618 (CHEMBL3752724) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500635 (CHEMBL3752318) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500615 (CHEMBL3753841) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50366824 (Avelox | MOXIFLOXACIN | Moxifl-oxacin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00266 BindingDB Entry DOI: 10.7270/Q2C251HR | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50605627 (CHEMBL5186061) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00266 BindingDB Entry DOI: 10.7270/Q2C251HR | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50500648 (CHEMBL3753342) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50516945 (CHEMBL4446054) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical School of Nanjing University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase | Eur J Med Chem 180: 648-655 (2019) Article DOI: 10.1016/j.ejmech.2019.07.057 BindingDB Entry DOI: 10.7270/Q2639T36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM21690 (1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Sassari Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as reduction in supercoiling of relaxed pBR322 DNA substrate after 30 mins by ethidium b... | Eur J Med Chem 161: 399-415 (2019) Article DOI: 10.1016/j.ejmech.2018.10.031 BindingDB Entry DOI: 10.7270/Q28D00KV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50366824 (Avelox | MOXIFLOXACIN | Moxifl-oxacin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of supercoiling activity using relaxed pBR322 plasmid as substrate after 3... | Bioorg Med Chem 24: 42-52 (2016) Article DOI: 10.1016/j.bmc.2015.11.039 BindingDB Entry DOI: 10.7270/Q25T3PG4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |
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