Found 88 hits of ic50 for UniProtKB: P30536 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Translocator protein
(Homo sapiens (Human)) | BDBM50122293
(CHEMBL401000 | CHEMBL63064 | N-(2,5-Dimethoxy-benz...)Show SMILES COc1ccc(OC)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1 Show InChI InChI=1S/C23H22FNO4/c1-16(26)25(15-17-13-20(27-2)10-12-22(17)28-3)21-14-18(24)9-11-23(21)29-19-7-5-4-6-8-19/h4-14H,15H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112924
BindingDB Entry DOI: 10.7270/Q25D8WSD |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50185957
(CHEMBL205767 | N-(2-isopropoxybenzyl)-N-(4-chloro-...)Show SMILES CC(C)Oc1ccccc1CN(C(C)=O)c1ccc(Cl)cc1Oc1ccccc1 Show InChI InChI=1S/C24H24ClNO3/c1-17(2)28-23-12-8-7-9-19(23)16-26(18(3)27)22-14-13-20(25)15-24(22)29-21-10-5-4-6-11-21/h4-15,17H,16H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112924
BindingDB Entry DOI: 10.7270/Q25D8WSD |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50185957
(CHEMBL205767 | N-(2-isopropoxybenzyl)-N-(4-chloro-...)Show SMILES CC(C)Oc1ccccc1CN(C(C)=O)c1ccc(Cl)cc1Oc1ccccc1 Show InChI InChI=1S/C24H24ClNO3/c1-17(2)28-23-12-8-7-9-19(23)16-26(18(3)27)22-14-13-20(25)15-24(22)29-21-10-5-4-6-11-21/h4-15,17H,16H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 125: 1172-1192 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.017
BindingDB Entry DOI: 10.7270/Q25Q4Z83 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM22032
(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 125: 1172-1192 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.017
BindingDB Entry DOI: 10.7270/Q25Q4Z83 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50210943
(CHEMBL3970955)Show SMILES COc1ccc(OC)c(CN(C(C)=O)c2ccc(F)cc2Oc2ccccc2)c1 Show InChI InChI=1S/C23H22FNO4/c1-16(26)25(15-17-13-20(27-2)10-12-22(17)28-3)21-11-9-18(24)14-23(21)29-19-7-5-4-6-8-19/h4-14H,15H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 125: 1172-1192 (2017)
Article DOI: 10.1016/j.ejmech.2016.11.017
BindingDB Entry DOI: 10.7270/Q25Q4Z83 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50530439
(CHEMBL4456416)Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(CC(=O)CCCCC(=O)Nc3ccn([C@@H]4O[C@H](CO)[C@@H](O)[C@@H]4O)c(=O)n3)cccn12)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C37H45ClN6O8/c1-3-16-42(17-4-2)31(48)21-27-32(23-11-13-25(38)14-12-23)41-35-24(8-7-18-43(27)35)20-26(46)9-5-6-10-30(47)39-29-15-19-44(37(51)40-29)36-34(50)33(49)28(22-45)52-36/h7-8,11-15,18-19,28,33-34,36,45,49-50H,3-6,9-10,16-17,20-22H2,1-2H3,(H,39,40,47,51)/t28-,33-,34+,36-/m1/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569
BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50530439
(CHEMBL4456416)Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(CC(=O)CCCCC(=O)Nc3ccn([C@@H]4O[C@H](CO)[C@@H](O)[C@@H]4O)c(=O)n3)cccn12)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C37H45ClN6O8/c1-3-16-42(17-4-2)31(48)21-27-32(23-11-13-25(38)14-12-23)41-35-24(8-7-18-43(27)35)20-26(46)9-5-6-10-30(47)39-29-15-19-44(37(51)40-29)36-34(50)33(49)28(22-45)52-36/h7-8,11-15,18-19,28,33-34,36,45,49-50H,3-6,9-10,16-17,20-22H2,1-2H3,(H,39,40,47,51)/t28-,33-,34+,36-/m1/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569
BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50588812
(CHEMBL5179737) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112924
BindingDB Entry DOI: 10.7270/Q25D8WSD |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM22041
(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23Cl2N3O/c1-3-11-25(12-4-2)20(27)13-18-21(15-5-7-16(22)8-6-15)24-19-10-9-17(23)14-26(18)19/h5-10,14H,3-4,11-13H2,1-2H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569
BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM22041
(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23Cl2N3O/c1-3-11-25(12-4-2)20(27)13-18-21(15-5-7-16(22)8-6-15)24-19-10-9-17(23)14-26(18)19/h5-10,14H,3-4,11-13H2,1-2H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569
BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50229594
(CHEMBL253597 | N-(2-methoxybenzyl)-N-(4-phenoxypyr...)Show InChI InChI=1S/C21H20N2O3/c1-16(24)23(15-17-8-6-7-11-20(17)25-2)19-14-22-13-12-21(19)26-18-9-4-3-5-10-18/h3-14H,15H2,1-2H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112924
BindingDB Entry DOI: 10.7270/Q25D8WSD |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50588813
(CHEMBL5199978) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112924
BindingDB Entry DOI: 10.7270/Q25D8WSD |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50060121
(2-(6-Nitro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N,...)Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(cn12)[N+]([O-])=O)-c1ccccc1 Show InChI InChI=1S/C21H24N4O3/c1-3-12-23(13-4-2)20(26)14-18-21(16-8-6-5-7-9-16)22-19-11-10-17(25(27)28)15-24(18)19/h5-11,15H,3-4,12-14H2,1-2H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569
BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50060121
(2-(6-Nitro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-N,...)Show SMILES CCCN(CCC)C(=O)Cc1c(nc2ccc(cn12)[N+]([O-])=O)-c1ccccc1 Show InChI InChI=1S/C21H24N4O3/c1-3-12-23(13-4-2)20(26)14-18-21(16-8-6-5-7-9-16)22-19-11-10-17(25(27)28)15-24(18)19/h5-11,15H,3-4,12-14H2,1-2H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Palack£ University
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
Eur J Med Chem 181: (2019)
Article DOI: 10.1016/j.ejmech.2019.111569
BindingDB Entry DOI: 10.7270/Q2H41VXG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50378900
(CHEMBL1672415)Show SMILES CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(=O)N(C)CCCCCCN(C)C(=O)c5cc6ccccc6c(n5)-c5ccccc5I)[C@@H]4C)c4cc(O)c5c(C)c(cc1[nH]2)nc45)c(C)c3C=C |r| Show InChI InChI=1S/C57H60IN7O3/c1-9-37-32(3)44-29-46-34(5)39(54(61-46)42-28-51(66)53-35(6)47(62-56(42)53)31-49-38(10-2)33(4)45(60-49)30-48(37)59-44)23-24-52(67)64(7)25-17-11-12-18-26-65(8)57(68)50-27-36-19-13-14-20-40(36)55(63-50)41-21-15-16-22-43(41)58/h9,13-16,19-22,27-31,34,39,59-60,66H,1,10-12,17-18,23-26H2,2-8H3/b44-29-,45-30-,46-29-,47-31-,48-30-,49-31-,54-42-/t34-,39-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50336914
(3-[(21S,22S)-16-ethenyl-11-ethyl-12,17,21,26-tetra...)Show SMILES CCc1c(C)c2cc3[nH]c(cc4[nH]c(c(CCC(=O)NCCCCCCNC(=O)c5cc6ccccc6c(n5)-c5ccccc5I)c4C)c4cc(O)c5c(C)c(cc1[nH]2)[nH]c45)c(C)c3C=C Show InChI InChI=1S/C55H56IN7O3/c1-7-35-30(3)42-27-44-32(5)37(52(61-44)40-26-49(64)51-33(6)45(62-54(40)51)29-47-36(8-2)31(4)43(60-47)28-46(35)59-42)21-22-50(65)57-23-15-9-10-16-24-58-55(66)48-25-34-17-11-12-18-38(34)53(63-48)39-19-13-14-20-41(39)56/h7,11-14,17-20,25-29,59-62,64H,1,8-10,15-16,21-24H2,2-6H3,(H,57,65)(H,58,66)/b42-27-,43-28-,44-27-,45-29-,46-28-,47-29-,52-40- | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50012189
(CHEMBL3265238)Show SMILES COc1cccc(NC[C@H](F)Cn2c3ccc(Br)cc3c3cc(Br)ccc23)n1 |r| Show InChI InChI=1S/C21H18Br2FN3O/c1-28-21-4-2-3-20(26-21)25-11-15(24)12-27-18-7-5-13(22)9-16(18)17-10-14(23)6-8-19(17)27/h2-10,15H,11-12H2,1H3,(H,25,26)/t15-/m0/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
J Med Chem 57: 3746-54 (2014)
Article DOI: 10.1021/jm401919s
BindingDB Entry DOI: 10.7270/Q2J38V3B |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM22032
(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50378901
(CHEMBL1672418)Show InChI InChI=1S/C21H21IN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50012191
(CHEMBL3265237)Show SMILES COc1cccc(NC[C@@H](F)Cn2c3ccc(Br)cc3c3cc(Br)ccc23)n1 |r| Show InChI InChI=1S/C21H18Br2FN3O/c1-28-21-4-2-3-20(26-21)25-11-15(24)12-27-18-7-5-13(22)9-16(18)17-10-14(23)6-8-19(17)27/h2-10,15H,11-12H2,1H3,(H,25,26)/t15-/m1/s1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
J Med Chem 57: 3746-54 (2014)
Article DOI: 10.1021/jm401919s
BindingDB Entry DOI: 10.7270/Q2J38V3B |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM220447
(US10633379, Compound X | US9296741, 36)Show SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C22H19F2N3O4S/c1-3-32(29,30)26-14-5-7-19(31-20-6-4-13(23)10-18(20)24)16(11-14)17-12-27(2)22(28)21-15(17)8-9-25-21/h4-12,25-26H,3H2,1-2H3 | KEGG
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| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
Curated by ChEMBL
| Assay Description
Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma |
J Med Chem 60: 8369-8384 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00746
BindingDB Entry DOI: 10.7270/Q2251MB8 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50378902
(CHEMBL1672414)Show SMILES CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(=O)N(C)CCN(C)C(=O)c5cc6ccccc6c(n5)-c5ccccc5I)[C@@H]4C)c4cc(O)c5c(C)c(cc1[nH]2)nc45)c(C)c3C=C |r| Show InChI InChI=1S/C53H52IN7O3/c1-9-33-28(3)40-25-42-30(5)35(50(57-42)38-24-47(62)49-31(6)43(58-52(38)49)27-45-34(10-2)29(4)41(56-45)26-44(33)55-40)19-20-48(63)60(7)21-22-61(8)53(64)46-23-32-15-11-12-16-36(32)51(59-46)37-17-13-14-18-39(37)54/h9,11-18,23-27,30,35,55-56,62H,1,10,19-22H2,2-8H3/b40-25-,41-26-,42-25-,43-27-,44-26-,45-27-,50-38-/t30-,35-/m0/s1 | KEGG
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50105061
(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)Show SMILES Clc1cc2OCOc2cc1COC(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H20ClN3O5/c22-15-10-19-18(29-12-30-19)9-13(15)11-28-21(27)24-7-5-14(6-8-24)25-17-4-2-1-3-16(17)23-20(25)26/h1-4,9-10,14H,5-8,11-12H2,(H,23,26) | KEGG
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| n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description
Binding affinity for peripheral benzodiazepine receptor |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50231767
(5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carbox...)Show InChI InChI=1S/C19H14N2O2/c1-13-3-2-4-16(11-13)21-19(22)18-10-9-17(23-18)15-7-5-14(12-20)6-8-15/h2-11H,1H3,(H,21,22) | KEGG
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| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to peripheral benzodiazepine receptor |
J Med Chem 51: 407-16 (2008)
Article DOI: 10.1021/jm070637u
BindingDB Entry DOI: 10.7270/Q2KK9CN7 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50012190
(CHEMBL2442625)Show SMILES COc1cccc(NCC(F)Cn2c3ccc(Br)cc3c3cc(Br)ccc23)c1 Show InChI InChI=1S/C22H19Br2FN2O/c1-28-18-4-2-3-17(11-18)26-12-16(25)13-27-21-7-5-14(23)9-19(21)20-10-15(24)6-8-22(20)27/h2-11,16,26H,12-13H2,1H3 | KEGG
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| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Southwestern Medical Center
Curated by ChEMBL
| Assay Description
Inhibition of TSPO (unknown origin) |
J Med Chem 57: 3746-54 (2014)
Article DOI: 10.1021/jm401919s
BindingDB Entry DOI: 10.7270/Q2J38V3B |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50212239
(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)Show SMILES COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1 Show InChI InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22) | KEGG
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| n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Binding affinity to peripheral benzodiazepine receptor |
J Med Chem 51: 407-16 (2008)
Article DOI: 10.1021/jm070637u
BindingDB Entry DOI: 10.7270/Q2KK9CN7 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50378903
(CHEMBL1672412)Show SMILES CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(=O)NCCNC(=O)c5cc6ccccc6c(n5)-c5ccccc5I)[C@@H]4C)c4cc(O)c5c(C)c(cc1[nH]2)nc45)c(C)c3C=C |r| Show InChI InChI=1S/C51H48IN7O3/c1-7-31-26(3)38-23-40-28(5)33(17-18-46(61)53-19-20-54-51(62)44-21-30-13-9-10-14-34(30)49(59-44)35-15-11-12-16-37(35)52)48(57-40)36-22-45(60)47-29(6)41(58-50(36)47)25-43-32(8-2)27(4)39(56-43)24-42(31)55-38/h7,9-16,21-25,28,33,55-56,60H,1,8,17-20H2,2-6H3,(H,53,61)(H,54,62)/b38-23-,39-24-,40-23-,41-25-,42-24-,43-25-,48-36-/t28-,33-/m0/s1 | KEGG
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| n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50378904
(CHEMBL1672411)Show SMILES CCc1c(C)c2cc3[nH]c(cc4[nH]c(c(CCC(=O)NCCN)c4C)c4cc(O)c5c(C)c(cc1[nH]2)[nH]c45)c(C)c3C=C Show InChI InChI=1S/C35H40N6O2/c1-7-21-17(3)25-14-27-19(5)23(9-10-32(43)37-12-11-36)34(40-27)24-13-31(42)33-20(6)28(41-35(24)33)16-30-22(8-2)18(4)26(39-30)15-29(21)38-25/h7,13-16,38-42H,1,8-12,36H2,2-6H3,(H,37,43)/b25-14-,26-15-,27-14-,28-16-,29-15-,30-16-,34-24- | KEGG
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| n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50378905
(CHEMBL1672410)Show SMILES CCc1c(C)c2cc3[nH]c(cc4[nH]c(c(CCC(=O)NCCCCCCN)c4C)c4cc(O)c5c(C)c(cc1[nH]2)[nH]c45)c(C)c3C=C Show InChI InChI=1S/C39H48N6O2/c1-7-25-21(3)29-18-31-23(5)27(13-14-36(47)41-16-12-10-9-11-15-40)38(44-31)28-17-35(46)37-24(6)32(45-39(28)37)20-34-26(8-2)22(4)30(43-34)19-33(25)42-29/h7,17-20,42-46H,1,8-16,40H2,2-6H3,(H,41,47)/b29-18-,30-19-,31-18-,32-20-,33-19-,34-20-,38-28- | KEGG
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UniChem
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| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-PK11195 from PBR after 1 hr by scintillation counting |
ACS Med Chem Lett 2: 136-141 (2011)
Article DOI: 10.1021/ml100211g
BindingDB Entry DOI: 10.7270/Q2F76DJG |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50422184
(CHEMBL140487 | Ro-20-1310)Show SMILES CC(C)(C)N1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:13| Show InChI InChI=1S/C19H19ClN2O/c1-19(2,3)22-16-10-9-14(20)11-15(16)18(21-12-17(22)23)13-7-5-4-6-8-13/h4-11H,12H2,1-3H3 | KEGG
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| CHEMBL
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PC sid
UniChem
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| n/a | n/a | 1.61E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50422187
(CHEMBL150977 | Ro-05-3418)Show InChI InChI=1S/C16H15N3O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10,17H2,1H3 | KEGG
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CHEMBL
PC cid
PC sid
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| n/a | n/a | 2.17E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50422188
(MOTRAZEPAM | Ro-06-9098)Show SMILES COCN1c2ccc(cc2C(=NCC1=O)c1ccccc1)[N+]([O-])=O |c:11| Show InChI InChI=1S/C17H15N3O4/c1-24-11-19-15-8-7-13(20(22)23)9-14(15)17(18-10-16(19)21)12-5-3-2-4-6-12/h2-9H,10-11H2,1H3 | KEGG
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| PC cid
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UniChem
| Article
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| n/a | n/a | 2.32E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50422186
(CHEMBL147144 | Ro-05-3072)Show InChI InChI=1S/C15H13N3O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9,16H2,(H,18,19) | KEGG
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CHEMBL
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PC sid
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| n/a | n/a | 2.58E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50083882
(1-Methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,...)Show InChI InChI=1S/C17H13N3O/c1-20-15-8-7-12(10-18)9-14(15)17(19-11-16(20)21)13-5-3-2-4-6-13/h2-9H,11H2,1H3 | KEGG
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| CHEMBL
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UniChem
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| n/a | n/a | 2.63E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50083899
(5-Phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one |...)Show InChI InChI=1S/C15H12N2O/c18-14-10-16-15(11-6-2-1-3-7-11)12-8-4-5-9-13(12)17-14/h1-9H,10H2,(H,17,18) | KEGG
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MCE
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PC sid
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 2.85E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50422185
(CHEMBL345284 | Ro-22-4683)Show SMILES CC(C)(C)N1c2ccc(cc2C(=NCC1=O)c1ccccc1F)[N+]([O-])=O |c:12| Show InChI InChI=1S/C19H18FN3O3/c1-19(2,3)22-16-9-8-12(23(25)26)10-14(16)18(21-11-17(22)24)13-6-4-5-7-15(13)20/h4-10H,11H2,1-3H3 | KEGG
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| CHEMBL
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PC sid
UniChem
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PubMed
| n/a | n/a | 3.33E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408007
(CHEMBL358955 | Ro-20-7736)Show InChI InChI=1S/C16H14FN3O2/c1-20-14-7-6-10(19-22)8-12(14)16(18-9-15(20)21)11-4-2-3-5-13(11)17/h2-8,19,22H,9H2,1H3 | KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.04E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408018
(HALAZEPAM)Show SMILES FC(F)(F)CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C17H12ClF3N2O/c18-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)22-9-15(24)23(14)10-17(19,20)21/h1-8H,9-10H2 | KEGG
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| n/a | n/a | 1.08E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408036
(7-Aminoclonazepam | CHEMBL1273 | Ro-05-4619)Show InChI InChI=1S/C15H12ClN3O/c16-12-4-2-1-3-10(12)15-11-7-9(17)5-6-13(11)19-14(20)8-18-15/h1-7H,8,17H2,(H,19,20) | KEGG
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CHEMBL
MCE
PC cid
PC sid
UniChem
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| n/a | n/a | 1.33E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408031
(CHEMBL151121 | Ro-20-1815)Show InChI InChI=1S/C16H14FN3O/c1-20-14-7-6-10(18)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)17/h2-8H,9,18H2,1H3 | KEGG
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CHEMBL
PC cid
PC sid
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| n/a | n/a | 1.53E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408039
(CHEMBL150925 | Ro-06-7263)Show SMILES CC1N=C(c2ccccc2)c2cc(Cl)ccc2N(Cl)C1=O |t:2| Show InChI InChI=1S/C16H12Cl2N2O/c1-10-16(21)20(18)14-8-7-12(17)9-13(14)15(19-10)11-5-3-2-4-6-11/h2-10H,1H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.04E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408033
(CHEMBL348694 | Ro-20-5397)Show InChI InChI=1S/C16H12N2O2/c19-10-11-6-7-14-13(8-11)16(17-9-15(20)18-14)12-4-2-1-3-5-12/h1-8,10H,9H2,(H,18,20) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.32E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50040701
(7,8-Dichloro-1-methyl-5-phenyl-1,3-dihydro-benzo[e...)Show SMILES CN1c2cc(Cl)c(Cl)cc2C(=NCC1=O)c1ccccc1 |c:11| Show InChI InChI=1S/C16H12Cl2N2O/c1-20-14-8-13(18)12(17)7-11(14)16(19-9-15(20)21)10-5-3-2-4-6-10/h2-8H,9H2,1H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.50E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408016
(RO-053061 | Ro-05-3061)Show InChI InChI=1S/C15H11FN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.50E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408021
(CHEMBL348664 | Ro-20-2533)Show InChI InChI=1S/C17H16N2O/c1-2-12-8-9-15-14(10-12)17(18-11-16(20)19-15)13-6-4-3-5-7-13/h3-10H,2,11H2,1H3,(H,19,20) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.77E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50336501
(10-acetyl-11-(4-(benzyloxy)-2-chlorophenyl)-6-hydr...)Show SMILES CC(=O)N1C(C2C(=O)CC(C)(C)CC2=Nc2c(O)cccc12)c1ccc(OCc2ccccc2)cc1Cl |c:14| Show InChI InChI=1S/C30H29ClN2O4/c1-18(34)33-24-10-7-11-25(35)28(24)32-23-15-30(2,3)16-26(36)27(23)29(33)21-13-12-20(14-22(21)31)37-17-19-8-5-4-6-9-19/h4-14,27,29,35H,15-17H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA
Curated by ChEMBL
| Assay Description
Inhibition of peripheral benzodiazepine BZD receptor by radioligand binding assay |
Antimicrob Agents Chemother 52: 4420-31 (2008)
Article DOI: 10.1128/AAC.00669-08
BindingDB Entry DOI: 10.7270/Q26M3732 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50336501
(10-acetyl-11-(4-(benzyloxy)-2-chlorophenyl)-6-hydr...)Show SMILES CC(=O)N1C(C2C(=O)CC(C)(C)CC2=Nc2c(O)cccc12)c1ccc(OCc2ccccc2)cc1Cl |c:14| Show InChI InChI=1S/C30H29ClN2O4/c1-18(34)33-24-10-7-11-25(35)28(24)32-23-15-30(2,3)16-26(36)27(23)29(33)21-13-12-20(14-22(21)31)37-17-19-8-5-4-6-9-19/h4-14,27,29,35H,15-17H2,1-3H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA
Curated by ChEMBL
| Assay Description
Inhibition of peripheral benzodiazepine BZD receptor by radioligand binding assay |
Antimicrob Agents Chemother 52: 4420-31 (2008)
Article DOI: 10.1128/AAC.00669-08
BindingDB Entry DOI: 10.7270/Q26M3732 |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408020
(CHEMBL150784 | Ro-20-2541)Show InChI InChI=1S/C17H12FN3O/c1-21-15-7-6-11(9-19)8-13(15)17(20-10-16(21)22)12-4-2-3-5-14(12)18/h2-8H,10H2,1H3 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.33E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408013
(CHEMBL151548 | Ro-07-6198)Show InChI InChI=1S/C15H9ClF2N2O/c16-8-4-5-9-12(6-8)20-13(21)7-19-15(9)14-10(17)2-1-3-11(14)18/h1-6H,7H2,(H,20,21) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.57E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50408009
(CHEMBL435684 | Ro-07-2750)Show SMILES OCCN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1F |c:12| Show InChI InChI=1S/C17H14ClFN2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)20-10-16(23)21(15)7-8-22/h1-6,9,22H,7-8,10H2 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.08E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard University
Curated by ChEMBL
| Assay Description
Binding affinity of compound towards Benzodiazepine receptor in a competition assay |
J Med Chem 39: 5246-56 (1997)
Article DOI: 10.1021/jm960536o
BindingDB Entry DOI: 10.7270/Q2NG4RTQ |
More data for this
Ligand-Target Pair | |
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