Compile Data Set for Download or QSAR

Found 613 hits of ki for UniProtKB: P54289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436666 (6-(3-(5-((4- (dimethylamino)-4-(3- hydroxyphenyl)p...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(CN3CCC(CC3)(N(C)C)c3cccc(O)c3)o1)C2=O Show InChI InChI=1S/C32H39N9O3/c1-5-33-31-34-20-26-28(35-31)39(4)16-17-41(30(26)43)24-10-6-8-22(18-24)29-37-36-27(44-29)21-40-14-12-32(13-15-40,38(2)3)23-9-7-11-25(42)19-23/h6-11,18-20,42H,5,12-17,21H2,1-4H3,(H,33,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436318 (2-(ethylamino)-9- methyl-6-(3-(5-methyl- 1,3,4-oxa...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(C)o1)C2=O Show InChI InChI=1S/C19H21N7O2/c1-4-20-19-21-11-15-16(22-19)25(3)8-9-26(18(15)27)14-7-5-6-13(10-14)17-24-23-12(2)28-17/h5-7,10-11H,4,8-9H2,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436666 (6-(3-(5-((4- (dimethylamino)-4-(3- hydroxyphenyl)p...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(CN3CCC(CC3)(N(C)C)c3cccc(O)c3)o1)C2=O Show InChI InChI=1S/C32H39N9O3/c1-5-33-31-34-20-26-28(35-31)39(4)16-17-41(30(26)43)24-10-6-8-22(18-24)29-37-36-27(44-29)21-40-14-12-32(13-15-40,38(2)3)23-9-7-11-25(42)19-23/h6-11,18-20,42H,5,12-17,21H2,1-4H3,(H,33,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436625 ((S)-6-(2-fluoro-4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)c(F)c1)c1cccs1 |r| Show InChI InChI=1S/C24H28FN5O3S/c1-26-9-8-20(21-5-4-12-34-21)33-17-7-6-16(19(25)13-17)15-30-11-10-29(2)22-18(23(30)31)14-27-24(28-22)32-3/h4-7,12-14,20,26H,8-11,15H2,1-3H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436621 ((S)-2-methoxy-9- methyl-6-(2-methyl- 4-(3-(methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)c(C)c1)c1cccs1 |r| Show InChI InChI=1S/C25H31N5O3S/c1-17-14-19(33-21(9-10-26-2)22-6-5-13-34-22)8-7-18(17)16-30-12-11-29(3)23-20(24(30)31)15-27-25(28-23)32-4/h5-8,13-15,21,26H,9-12,16H2,1-4H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436566 ((R)-9-methyl-2- (methyl(pyridin-3- ylmethyl)amino)...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(ncc2C1=O)N(C)Cc1cccnc1)c1ccccc1 |r| Show InChI InChI=1S/C32H37N7O2/c1-33-16-14-29(26-11-5-4-6-12-26)41-23-24-9-7-13-27(19-24)39-18-17-37(2)30-28(31(39)40)21-35-32(36-30)38(3)22-25-10-8-15-34-20-25/h4-13,15,19-21,29,33H,14,16-18,22-23H2,1-3H3/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436567 ((R)-9-methyl-6-(3-((3- (methylamino)-1- phenylprop...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(NCc3ccccn3)ncc2C1=O)c1ccccc1 |r| Show InChI InChI=1S/C31H35N7O2/c1-32-16-14-28(24-10-4-3-5-11-24)40-22-23-9-8-13-26(19-23)38-18-17-37(2)29-27(30(38)39)21-35-31(36-29)34-20-25-12-6-7-15-33-25/h3-13,15,19,21,28,32H,14,16-18,20,22H2,1-2H3,(H,34,35,36)/t28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436568 ((R)-2-(((5- fluoropyridin-2- yl)methyl)(methyl) am...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(ncc2C1=O)N(C)Cc1ccc(F)cn1)c1ccccc1 |r| Show InChI InChI=1S/C32H36FN7O2/c1-34-15-14-29(24-9-5-4-6-10-24)42-22-23-8-7-11-27(18-23)40-17-16-38(2)30-28(31(40)41)20-36-32(37-30)39(3)21-26-13-12-25(33)19-35-26/h4-13,18-20,29,34H,14-17,21-22H2,1-3H3/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436569 (2-(ethylamino)-6-(3- ((3-((2-fluoroethyl) amino)-1...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(COC(CCNCCF)c3cccs3)c1)C2=O Show InChI InChI=1S/C26H33FN6O2S/c1-3-29-26-30-17-21-24(31-26)32(2)13-14-33(25(21)34)20-7-4-6-19(16-20)18-35-22(9-11-28-12-10-27)23-8-5-15-36-23/h4-8,15-17,22,28H,3,9-14,18H2,1-2H3,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436571 ((R)-2-amino-9-methyl- 6-(3-((3-(methylamino)- 1-(t...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(N)ncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C23H28N6O2S/c1-25-9-8-19(20-7-4-12-32-20)31-15-16-5-3-6-17(13-16)29-11-10-28(2)21-18(22(29)30)14-26-23(24)27-21/h3-7,12-14,19,25H,8-11,15H2,1-2H3,(H2,24,26,27)/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436573 (2-(ethylamino)-9- methyl-6-(3-(3- (methylamino)-1-...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(OC(CCNC)c3ccsc3)c1)C2=O Show InChI InChI=1S/C24H30N6O2S/c1-4-26-24-27-15-20-22(28-24)29(3)11-12-30(23(20)31)18-6-5-7-19(14-18)32-21(8-10-25-2)17-9-13-33-16-17/h5-7,9,13-16,21,25H,4,8,10-12H2,1-3H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436574 ((S)-2-(ethylamino)-9- methyl-6-(3-(3- (methylamino...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(O[C@@H](CCNC)c3ccsc3)c1)C2=O |r| Show InChI InChI=1S/C24H30N6O2S/c1-4-26-24-27-15-20-22(28-24)29(3)11-12-30(23(20)31)18-6-5-7-19(14-18)32-21(8-10-25-2)17-9-13-33-16-17/h5-7,9,13-16,21,25H,4,8,10-12H2,1-3H3,(H,26,27,28)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436576 ((S)-2-amino-9-methyl- 6-(3-(3-(methylamino)- 1-(th...) Show SMILES CNCC[C@H](Oc1cccc(c1)N1CCN(C)c2nc(N)ncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C22H26N6O2S/c1-24-9-8-18(19-7-4-12-31-19)30-16-6-3-5-15(13-16)28-11-10-27(2)20-17(21(28)29)14-25-22(23)26-20/h3-7,12-14,18,24H,8-11H2,1-2H3,(H2,23,25,26)/t18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436584 ((R)-2,9-dimethyl-6-(3- ((3-(methylamino)-1- (thiop...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(C)ncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C24H29N5O2S/c1-17-26-15-20-23(27-17)28(3)11-12-29(24(20)30)19-7-4-6-18(14-19)16-31-21(9-10-25-2)22-8-5-13-32-22/h4-8,13-15,21,25H,9-12,16H2,1-3H3/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436588 ((S)-9-methyl-6-(3-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1cccc(c1)N1CCN(C)c2ncncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C22H25N5O2S/c1-23-9-8-19(20-7-4-12-30-20)29-17-6-3-5-16(13-17)27-11-10-26(2)21-18(22(27)28)14-24-15-25-21/h3-7,12-15,19,23H,8-11H2,1-2H3/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436599 ((S)-2-methoxy-9- methyl-6-(4-(3- (methylamino)-1- ...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1)c1ccccc1 |r| Show InChI InChI=1S/C26H31N5O3/c1-27-14-13-23(20-7-5-4-6-8-20)34-21-11-9-19(10-12-21)18-31-16-15-30(2)24-22(25(31)32)17-28-26(29-24)33-3/h4-12,17,23,27H,13-16,18H2,1-3H3/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436603 ((S)-9-methyl-6-(4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(SC)ncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C24H29N5O2S2/c1-25-11-10-20(21-5-4-14-33-21)31-18-8-6-17(7-9-18)16-29-13-12-28(2)22-19(23(29)30)15-26-24(27-22)32-3/h4-9,14-15,20,25H,10-13,16H2,1-3H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436605 (1-methyl-4-(4-(3- (methylamino)-1- (thiophen-2- yl...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3ccncc3C2=O)cc1)c1cccs1 Show InChI InChI=1S/C24H28N4O2S/c1-25-11-10-22(23-4-3-15-31-23)30-19-7-5-18(6-8-19)17-28-14-13-27(2)21-9-12-26-16-20(21)24(28)29/h3-9,12,15-16,22,25H,10-11,13-14,17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436606 ((S)-1-methyl-4-(4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ccncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C24H28N4O2S/c1-25-11-10-22(23-4-3-15-31-23)30-19-7-5-18(6-8-19)17-28-14-13-27(2)21-9-12-26-16-20(21)24(28)29/h3-9,12,15-16,22,25H,10-11,13-14,17H2,1-2H3/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436607 ((S)-8-(ethylamino)-1- methyl-4-(4-(3- (methylamino...) Show SMILES CCNc1cc2N(C)CCN(Cc3ccc(O[C@@H](CCNC)c4cccs4)cc3)C(=O)c2cn1 |r| Show InChI InChI=1S/C26H33N5O2S/c1-4-28-25-16-22-21(17-29-25)26(32)31(14-13-30(22)3)18-19-7-9-20(10-8-19)33-23(11-12-27-2)24-6-5-15-34-24/h5-10,15-17,23,27H,4,11-14,18H2,1-3H3,(H,28,29)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436608 ((S)-8- (dimethylamino)-1- methyl-4-(4-(3- (methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3cc(ncc3C2=O)N(C)C)cc1)c1cccs1 |r| Show InChI InChI=1S/C26H33N5O2S/c1-27-12-11-23(24-6-5-15-34-24)33-20-9-7-19(8-10-20)18-31-14-13-30(4)22-16-25(29(2)3)28-17-21(22)26(31)32/h5-10,15-17,23,27H,11-14,18H2,1-4H3/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436609 ((S)-8-methoxy-1- methyl-4-(4-(3- (methylamino)-1- ...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3cc(OC)ncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C25H30N4O3S/c1-26-11-10-22(23-5-4-14-33-23)32-19-8-6-18(7-9-19)17-29-13-12-28(2)21-15-24(31-3)27-16-20(21)25(29)30/h4-9,14-16,22,26H,10-13,17H2,1-3H3/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436610 ((S)-9-methyl-6-(4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(ncc3C2=O)C(F)(F)F)cc1)c1cccs1 |r| Show InChI InChI=1S/C24H26F3N5O2S/c1-28-10-9-19(20-4-3-13-35-20)34-17-7-5-16(6-8-17)15-32-12-11-31(2)21-18(22(32)33)14-29-23(30-21)24(25,26)27/h3-8,13-14,19,28H,9-12,15H2,1-2H3/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436611 (2-methoxy-9-methyl- 6-(4-(3- (methylamino)-1- (thi...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1)c1ccsc1 Show InChI InChI=1S/C24H29N5O3S/c1-25-10-8-21(18-9-13-33-16-18)32-19-6-4-17(5-7-19)15-29-12-11-28(2)22-20(23(29)30)14-26-24(27-22)31-3/h4-7,9,13-14,16,21,25H,8,10-12,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436613 ((S)-1-ethyl-8- methoxy-4-(4-(3- (methylamino)-1- (...) Show SMILES CCN1CCN(Cc2ccc(O[C@@H](CCNC)c3cccs3)cc2)C(=O)c2cnc(OC)cc12 |r| Show InChI InChI=1S/C26H32N4O3S/c1-4-29-13-14-30(26(31)21-17-28-25(32-3)16-22(21)29)18-19-7-9-20(10-8-19)33-23(11-12-27-2)24-6-5-15-34-24/h5-10,15-17,23,27H,4,11-14,18H2,1-3H3/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436614 (2-methoxy-9-methyl- 6-(4-(3- (methylamino)-1- (thi...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1)c1nccs1 Show InChI InChI=1S/C23H28N6O3S/c1-24-9-8-19(21-25-10-13-33-21)32-17-6-4-16(5-7-17)15-29-12-11-28(2)20-18(22(29)30)14-26-23(27-20)31-3/h4-7,10,13-14,19,24H,8-9,11-12,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436615 ((S)-1-ethyl-4-(4-(3- (methylamino)-1- (thiophen-2-...) Show SMILES CCN1CCN(Cc2ccc(O[C@@H](CCNC)c3cccs3)cc2)C(=O)c2cnccc12 |r| Show InChI InChI=1S/C25H30N4O2S/c1-3-28-14-15-29(25(30)21-17-27-13-10-22(21)28)18-19-6-8-20(9-7-19)31-23(11-12-26-2)24-5-4-16-32-24/h4-10,13,16-17,23,26H,3,11-12,14-15,18H2,1-2H3/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436616 (2-methoxy-9-methyl- 6-(4-(3- (methylamino)-1-(5- m...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1)c1ccc(C)s1 Show InChI InChI=1S/C25H31N5O3S/c1-17-5-10-22(34-17)21(11-12-26-2)33-19-8-6-18(7-9-19)16-30-14-13-29(3)23-20(24(30)31)15-27-25(28-23)32-4/h5-10,15,21,26H,11-14,16H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436617 ((S)-2-methoxy-9- methyl-6-(3-methyl- 4-(3-(methyla...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1C)c1cccs1 |r| Show InChI InChI=1S/C25H31N5O3S/c1-17-14-18(7-8-20(17)33-21(9-10-26-2)22-6-5-13-34-22)16-30-12-11-29(3)23-19(24(30)31)15-27-25(28-23)32-4/h5-8,13-15,21,26H,9-12,16H2,1-4H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436618 ((S)-6-(3-fluoro-4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1F)c1cccs1 |r| Show InChI InChI=1S/C24H28FN5O3S/c1-26-9-8-20(21-5-4-12-34-21)33-19-7-6-16(13-18(19)25)15-30-11-10-29(2)22-17(23(30)31)14-27-24(28-22)32-3/h4-7,12-14,20,26H,8-11,15H2,1-3H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436619 ((S)-9-ethyl-2- methoxy-6-(4-(3- (methylamino)-1- (...) Show SMILES CCN1CCN(Cc2ccc(O[C@@H](CCNC)c3cccs3)cc2)C(=O)c2cnc(OC)nc12 |r| Show InChI InChI=1S/C25H31N5O3S/c1-4-29-13-14-30(24(31)20-16-27-25(32-3)28-23(20)29)17-18-7-9-19(10-8-18)33-21(11-12-26-2)22-6-5-15-34-22/h5-10,15-16,21,26H,4,11-14,17H2,1-3H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436620 (2-methoxy-9-methyl- 6-(4-(3- (methylamino)-1-(4- m...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1)c1cc(C)cs1 Show InChI InChI=1S/C25H31N5O3S/c1-17-13-22(34-16-17)21(9-10-26-2)33-19-7-5-18(6-8-19)15-30-12-11-29(3)23-20(24(30)31)14-27-25(28-23)32-4/h5-8,13-14,16,21,26H,9-12,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436622 ((S)-9-ethyl-6-(4-(3- (methylamino)-1- (thiophen-2-...) Show SMILES CCN1CCN(Cc2ccc(O[C@@H](CCNC)c3cccs3)cc2)C(=O)c2cncnc12 |r| Show InChI InChI=1S/C24H29N5O2S/c1-3-28-12-13-29(24(30)20-15-26-17-27-23(20)28)16-18-6-8-19(9-7-18)31-21(10-11-25-2)22-5-4-14-32-22/h4-9,14-15,17,21,25H,3,10-13,16H2,1-2H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436623 ((S)-9-fluoro-1- methyl-4-(4-(3- (methylamino)-1- (...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3c(F)cncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C24H27FN4O2S/c1-26-10-9-21(22-4-3-13-32-22)31-18-7-5-17(6-8-18)16-29-12-11-28(2)23-19(24(29)30)14-27-15-20(23)25/h3-8,13-15,21,26H,9-12,16H2,1-2H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436626 ((S)-2-methoxy-9- methyl-6-(4-(3- (methylamino)-1- ...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(OC)ncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C24H29N5O3S/c1-25-11-10-20(21-5-4-14-33-21)32-18-8-6-17(7-9-18)16-29-13-12-28(2)22-19(23(29)30)15-26-24(27-22)31-3/h4-9,14-15,20,25H,10-13,16H2,1-3H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436631 (2-(ethylamino)-9- methyl-6-(3-(3- (methylamino)-1-...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(Cc1cccc(OC(CCNC)c3ccccc3)c1)C2=O Show InChI InChI=1S/C27H34N6O2/c1-4-29-27-30-18-23-25(31-27)32(3)15-16-33(26(23)34)19-20-9-8-12-22(17-20)35-24(13-14-28-2)21-10-6-5-7-11-21/h5-12,17-18,24,28H,4,13-16,19H2,1-3H3,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436641 ((S)-2-(ethylamino)-9- methyl-6-(4-(3- (methylamino...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(Cc1ccc(O[C@@H](CCNC)c3cccs3)cc1)C2=O |r| Show InChI InChI=1S/C25H32N6O2S/c1-4-27-25-28-16-20-23(29-25)30(3)13-14-31(24(20)32)17-18-7-9-19(10-8-18)33-21(11-12-26-2)22-6-5-15-34-22/h5-10,15-16,21,26H,4,11-14,17H2,1-3H3,(H,27,28,29)/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436643 ((S)-2-(dimethylamino)- 9-methyl-6-(4-(3- (methylam...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(ncc3C2=O)N(C)C)cc1)c1cccs1 |r| Show InChI InChI=1S/C25H32N6O2S/c1-26-12-11-21(22-6-5-15-34-22)33-19-9-7-18(8-10-19)17-31-14-13-30(4)23-20(24(31)32)16-27-25(28-23)29(2)3/h5-10,15-16,21,26H,11-14,17H2,1-4H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436644 ((S)-2-amino-9-methyl- 6-(4-(3-(methylamino)- 1-(th...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(N)ncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C23H28N6O2S/c1-25-10-9-19(20-4-3-13-32-20)31-17-7-5-16(6-8-17)15-29-12-11-28(2)21-18(22(29)30)14-26-23(24)27-21/h3-8,13-14,19,25H,9-12,15H2,1-2H3,(H2,24,26,27)/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436652 ((S)-2,9-dimethyl-6-(4- (3-(methylamino)-1- (thioph...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3nc(C)ncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C24H29N5O2S/c1-17-26-15-20-23(27-17)28(3)12-13-29(24(20)30)16-18-6-8-19(9-7-18)31-21(10-11-25-2)22-5-4-14-32-22/h4-9,14-15,21,25H,10-13,16H2,1-3H3/t21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436659 (9-methyl-6-(4-(3- (methylamino)-1- (thiophen-2- yl...) Show SMILES CNCCC(Oc1ccc(CN2CCN(C)c3ncncc3C2=O)cc1)c1cccs1 Show InChI InChI=1S/C23H27N5O2S/c1-24-10-9-20(21-4-3-13-31-21)30-18-7-5-17(6-8-18)15-28-12-11-27(2)22-19(23(28)29)14-25-16-26-22/h3-8,13-14,16,20,24H,9-12,15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436660 ((S)-9-methyl-6-(4-(3- (methylamino)-1- (thiophen-2...) Show SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncncc3C2=O)cc1)c1cccs1 |r| Show InChI InChI=1S/C23H27N5O2S/c1-24-10-9-20(21-4-3-13-31-21)30-18-7-5-17(6-8-18)15-28-12-11-27(2)22-19(23(28)29)14-25-16-26-22/h3-8,13-14,16,20,24H,9-12,15H2,1-2H3/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436665 (6-(3-(5-((4- (dimethylamino)-4- phenylpiperidin-1-...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-c1nnc(CN3CCC(CC3)(N(C)C)c3ccccc3)o1)C2=O Show InChI InChI=1S/C32H39N9O2/c1-5-33-31-34-21-26-28(35-31)39(4)18-19-41(30(26)42)25-13-9-10-23(20-25)29-37-36-27(43-29)22-40-16-14-32(15-17-40,38(2)3)24-11-7-6-8-12-24/h6-13,20-21H,5,14-19,22H2,1-4H3,(H,33,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436389 ((R)-9-methyl-6-(3-((3- (methylamino)-1- phenylprop...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(SC)ncc2C1=O)c1ccccc1 |r| Show InChI InChI=1S/C26H31N5O2S/c1-27-13-12-23(20-9-5-4-6-10-20)33-18-19-8-7-11-21(16-19)31-15-14-30(2)24-22(25(31)32)17-28-26(29-24)34-3/h4-11,16-17,23,27H,12-15,18H2,1-3H3/t23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436394 (6-(3-(3- (benzylamino)propoxy) phenyl)-2- (ethylam...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(OCCCNCc3ccccc3)c1)C2=O Show InChI InChI=1S/C26H32N6O2/c1-3-28-26-29-19-23-24(30-26)31(2)14-15-32(25(23)33)21-11-7-12-22(17-21)34-16-8-13-27-18-20-9-5-4-6-10-20/h4-7,9-12,17,19,27H,3,8,13-16,18H2,1-2H3,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436407 (6-(3-(4- ((benzylamino)methyl)- 1H-1,2,3-triazol-1...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-n1cc(CNCc3ccccc3)nn1)C2=O Show InChI InChI=1S/C26H29N9O/c1-3-28-26-29-17-23-24(30-26)33(2)12-13-34(25(23)36)21-10-7-11-22(14-21)35-18-20(31-32-35)16-27-15-19-8-5-4-6-9-19/h4-11,14,17-18,27H,3,12-13,15-16H2,1-2H3,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436408 (2-(ethylamino)-9- methyl-6-(3-(4-(2- (methylamino)...) Show SMILES CCNc1ncc2c(n1)N(C)CCN(c1cccc(c1)-n1cc(CCNC)nn1)C2=O Show InChI InChI=1S/C21H27N9O/c1-4-23-21-24-13-18-19(25-21)28(3)10-11-29(20(18)31)16-6-5-7-17(12-16)30-14-15(26-27-30)8-9-22-2/h5-7,12-14,22H,4,8-11H2,1-3H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436430 ((R)-2-hydroxy-9- methyl-6-(3-((3- (methylamino)-1-...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(O)ncc2C1=O)c1ccccc1 |r| Show InChI InChI=1S/C25H29N5O3/c1-26-12-11-22(19-8-4-3-5-9-19)33-17-18-7-6-10-20(15-18)30-14-13-29(2)23-21(24(30)31)16-27-25(32)28-23/h3-10,15-16,22,26H,11-14,17H2,1-2H3,(H,27,28,32)/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436431 ((R)-2,9-dimethyl-6-(3- ((3-(methylamino)-1- phenyl...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(C)ncc2C1=O)c1ccccc1 |r| Show InChI InChI=1S/C26H31N5O2/c1-19-28-17-23-25(29-19)30(3)14-15-31(26(23)32)22-11-7-8-20(16-22)18-33-24(12-13-27-2)21-9-5-4-6-10-21/h4-11,16-17,24,27H,12-15,18H2,1-3H3/t24-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103] (Homo sapiens (Human))	BDBM436434 ((R)-9-methyl-6-(3-((3- (methylamino)-1- (thiophen-...) Show SMILES CNCC[C@@H](OCc1cccc(c1)N1CCN(C)c2nc(SC)ncc2C1=O)c1cccs1 |r| Show InChI InChI=1S/C24H29N5O2S2/c1-25-10-9-20(21-8-5-13-33-21)31-16-17-6-4-7-18(14-17)29-12-11-28(2)22-19(23(29)30)15-26-24(27-22)32-3/h4-8,13-15,20,25H,9-12,16H2,1-3H3/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ESTEVE PHARMACEUTICALS, S.A. US Patent					Assay Description α2δ-1: Binding Assay to Human α2δ-1 Subunit of Cav2.2 Calcium Channel.Human α2δ-1 enriched membranes (2.5 μg) were...				US Patent US10590140 (2020) BindingDB Entry DOI: 10.7270/Q2WM1HGR
					More data for this Ligand-Target Pair

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