Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.570 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.21 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.64 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.01 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.66 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Blk (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 15.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 24.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 37.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 39.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 62.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 87.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Nek1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 184 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 201 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C zeta type (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 204 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 243 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 385 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Nek1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 433 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [1-999,E255K] (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 438 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiopoietin-1 receptor (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK2 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 813 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage-stimulating protein receptor (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase WNK2 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase WNK2 (Homo sapiens (Human)) | BDBM139540 (US10189849, staurosporine | US10307427, Staurospor...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform epsilon (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Nek1 (Homo sapiens (Human)) | BDBM139539 (US8889696, 39) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Temple University—Of The Commonwealth System Of Higher Education US Patent | Assay Description The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase... | US Patent US8889696 (2014) BindingDB Entry DOI: 10.7270/Q2930RVR | |||||||||||
More data for this Ligand-Target Pair |
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