Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2278 (3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2284 (5-chloro-3-(phenylsulfanyl)-1H-indole-2-carboxamid...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2287 (5-chloro-N-methyl-3-(phenylsulfanyl)-1H-indole-2-c...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2288 (3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM1317 (3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2279 (2-[(benzenesulfinyl)methyl]-3-(phenylsulfanyl)-1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1) | BDBM2278 (3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 71 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 101 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2280 (2-[(benzenesulfinyl)methyl]-5-chloro-3-(phenylsulf...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM2278 (3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2283 (5Cl3PhS-2IndolCONH2 inhibitor 9b | methyl 5-chloro...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 156 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM1868 ((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 311 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM1317 (3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 545 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2286 (5Cl3PhS-2IndolCONH2 inhibitor 12 | N-methyl-3-(phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 746 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1) | BDBM2284 (5-chloro-3-(phenylsulfanyl)-1H-indole-2-carboxamid...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM1437 (5-methoxyindole-2-carboxylic acid [N -[3-(aminoeth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1) | BDBM2288 (3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.39E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM2284 (5-chloro-3-(phenylsulfanyl)-1H-indole-2-carboxamid...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.46E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2282 (5Cl3PhS-2IndolCONH2 inhibitor 9a | cid_454848 | me...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM2279 (2-[(benzenesulfinyl)methyl]-3-(phenylsulfanyl)-1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM2288 (3-(benzenesulfinyl)-5-chloro-1H-indole-2-carboxami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.76E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1) | BDBM2279 (2-[(benzenesulfinyl)methyl]-3-(phenylsulfanyl)-1H-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.99E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM1868 ((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 7.32E+3 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1) | BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1) | BDBM1317 (3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM1437 (5-methoxyindole-2-carboxylic acid [N -[3-(aminoeth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.34E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1) | BDBM1868 ((+)-(5S)-4,5,6,7-tetrahydro-9-chloro 5-methyl-6-(3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 3.95E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1) | BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 5.79E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2281 (3-(benzenesulfinyl)-2-[(benzenesulfinyl)methyl]-1H...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.28E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1) | BDBM2285 (5Cl3PhS-2IndolCONH2 inhibitor 11 | N,N-dimethyl-3-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.76E+4 | n/a | n/a | n/a | n/a | 8.2 | n/a |
Merck Research Laboratories | Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro. | J Med Chem 36: 1291-4 (1993) Article DOI: 10.1021/jm00061a022 BindingDB Entry DOI: 10.7270/Q2RV0KWR | |||||||||||
More data for this Ligand-Target Pair |