Compile Data Set for Download or QSAR

Found 118 hits Enz. Inhib. hit(s) with all data for entry = 7295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186994 (US9169209, Table 3, Compound 25) Show SMILES CC(C)Oc1cccc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C23H22N2O4S/c1-17(2)29-20-6-3-7-22(15-20)30(27,28)21-11-9-19(10-12-21)25-23(26)13-8-18-5-4-14-24-16-18/h3-17H,1-2H3,(H,25,26)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186981 (US9169209, Table 3, Compound 12) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cncc(c1)N1CCCC1)\C=C\c1cccnc1 Show InChI InChI=1S/C23H22N4O3S/c28-23(10-5-18-4-3-11-24-15-18)26-19-6-8-21(9-7-19)31(29,30)22-14-20(16-25-17-22)27-12-1-2-13-27/h3-11,14-17H,1-2,12-13H2,(H,26,28)/b10-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187028 (US9169209, Table 3, Compound 61) Show SMILES COc1ccc(C)cc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H20N2O4S/c1-16-5-11-20(28-2)21(14-16)29(26,27)19-9-7-18(8-10-19)24-22(25)12-6-17-4-3-13-23-15-17/h3-15H,1-2H3,(H,24,25)/b12-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187007 (US9169209, Table 3, Compound 39) Show SMILES Cn1ncc2cc(ccc12)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H18N4O3S/c1-26-21-10-9-20(13-17(21)15-24-26)30(28,29)19-7-5-18(6-8-19)25-22(27)11-4-16-3-2-12-23-14-16/h2-15H,1H3,(H,25,27)/b11-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187065 (US9169209, Table 3, Compound 98) Show SMILES Fc1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C20H15FN2O3S/c21-16-4-8-18(9-5-16)27(25,26)19-10-6-17(7-11-19)23-20(24)12-3-15-2-1-13-22-14-15/h1-14H,(H,23,24)/b12-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187005 (US9169209, Table 3, Compound 37) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc2[nH]ccc12)\C=C\c1cccnc1 Show InChI InChI=1S/C22H17N3O3S/c26-22(11-6-16-3-2-13-23-15-16)25-17-7-9-18(10-8-17)29(27,28)21-5-1-4-20-19(21)12-14-24-20/h1-15,24H,(H,25,26)/b11-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187023 (US9169209, Table 3, Compound 56) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cncc2ccccc12)\C=C\c1cccnc1 Show InChI InChI=1S/C23H17N3O3S/c27-23(12-7-17-4-3-13-24-14-17)26-19-8-10-20(11-9-19)30(28,29)22-16-25-15-18-5-1-2-6-21(18)22/h1-16H,(H,26,27)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.45	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187032 (US9169209, Table 3, Compound 65) Show SMILES COc1ccc(cc1OC)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H20N2O5S/c1-28-20-11-10-19(14-21(20)29-2)30(26,27)18-8-6-17(7-9-18)24-22(25)12-5-16-4-3-13-23-15-16/h3-15H,1-2H3,(H,24,25)/b12-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186984 (US9169209, Table 3, Compound 15) Show SMILES COc1ccc(cc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1)C(C)C Show InChI InChI=1S/C24H24N2O4S/c1-17(2)19-7-12-22(30-3)23(15-19)31(28,29)21-10-8-20(9-11-21)26-24(27)13-6-18-5-4-14-25-16-18/h4-17H,1-3H3,(H,26,27)/b13-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187008 (US9169209, Table 3, Compound 40) Show SMILES Cn1ncc2ccc(cc12)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H18N4O3S/c1-26-21-13-20(8-5-17(21)15-24-26)30(28,29)19-9-6-18(7-10-19)25-22(27)11-4-16-3-2-12-23-14-16/h2-15H,1H3,(H,25,27)/b11-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187012 (US9169209, Table 3, Compound 44) Show SMILES CCCn1cc(cn1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C20H20N4O3S/c1-2-12-24-15-19(14-22-24)28(26,27)18-8-6-17(7-9-18)23-20(25)10-5-16-4-3-11-21-13-16/h3-11,13-15H,2,12H2,1H3,(H,23,25)/b10-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM60806 (US9169209, Table 3, Compound 3) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)N1CC2CCC(C1)O2)\C=C\c1cccnc1 Show InChI InChI=1S/C20H21N3O4S/c24-20(10-3-15-2-1-11-21-12-15)22-16-4-8-19(9-5-16)28(25,26)23-13-17-6-7-18(14-23)27-17/h1-5,8-12,17-18H,6-7,13-14H2,(H,22,24)/b10-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187026 (US9169209, Table 3, Compound 59) Show SMILES O=C(NCc1ccc(cc1)S(=O)(=O)c1ccccc1)\C=C\c1cccnc1 Show InChI InChI=1S/C21H18N2O3S/c24-21(13-10-17-5-4-14-22-15-17)23-16-18-8-11-20(12-9-18)27(25,26)19-6-2-1-3-7-19/h1-15H,16H2,(H,23,24)/b13-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187049 (US9169209, Table 3, Compound 82) Show SMILES COc1cc(F)cc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H17FN2O4S/c1-28-18-11-16(22)12-20(13-18)29(26,27)19-7-5-17(6-8-19)24-21(25)9-4-15-3-2-10-23-14-15/h2-14H,1H3,(H,24,25)/b9-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187045 (US9169209, Table 3, Compound 78) Show SMILES CCc1cccc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H20N2O3S/c1-2-17-5-3-7-21(15-17)28(26,27)20-11-9-19(10-12-20)24-22(25)13-8-18-6-4-14-23-16-18/h3-16H,2H2,1H3,(H,24,25)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187003 (US9169209, Table 3, Compound 34) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc2c3ccccc3oc12)\C=C\c1cccnc1 Show InChI InChI=1S/C26H18N2O4S/c29-25(15-10-18-5-4-16-27-17-18)28-19-11-13-20(14-12-19)33(30,31)24-9-3-7-22-21-6-1-2-8-23(21)32-26(22)24/h1-17H,(H,28,29)/b15-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186970 (US9169209, Table 3, Compound 1) Show SMILES FC(F)(F)Oc1ccccc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H15F3N2O4S/c22-21(23,24)30-18-5-1-2-6-19(18)31(28,29)17-10-8-16(9-11-17)26-20(27)12-7-15-4-3-13-25-14-15/h1-14H,(H,26,27)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186979 (US9169209, Table 3, Compound 10) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc2cccnc12)\C=C\c1cccnc1 Show InChI InChI=1S/C23H17N3O3S/c27-22(13-8-17-4-2-14-24-16-17)26-19-9-11-20(12-10-19)30(28,29)21-7-1-5-18-6-3-15-25-23(18)21/h1-16H,(H,26,27)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186977 (US9169209, Table 3, Compound 8) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cnc2ccccc2c1)\C=C\c1cccnc1 Show InChI InChI=1S/C23H17N3O3S/c27-23(12-7-17-4-3-13-24-15-17)26-19-8-10-20(11-9-19)30(28,29)21-14-18-5-1-2-6-22(18)25-16-21/h1-16H,(H,26,27)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439677 (CHEMBL2417790 | US9169209, Table 3, Compound 55) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1ccccc1)\C=C\c1cccnc1 Show InChI InChI=1S/C20H16N2O3S/c23-20(13-8-16-5-4-14-21-15-16)22-17-9-11-19(12-10-17)26(24,25)18-6-2-1-3-7-18/h1-15H,(H,22,23)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187058 (US9169209, Table 3, Compound 91) Show SMILES CCOc1cc(Cl)ccc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H19ClN2O4S/c1-2-29-20-14-17(23)6-11-21(20)30(27,28)19-9-7-18(8-10-19)25-22(26)12-5-16-4-3-13-24-15-16/h3-15H,2H2,1H3,(H,25,26)/b12-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187024 (US9169209, Table 3, Compound 57) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc2ccccc12)\C=C\c1cccnc1 Show InChI InChI=1S/C24H18N2O3S/c27-24(15-10-18-5-4-16-25-17-18)26-20-11-13-21(14-12-20)30(28,29)23-9-3-7-19-6-1-2-8-22(19)23/h1-17H,(H,26,27)/b15-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187069 (US9169209, Table 3, Compound 102) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1)\C=C\c1cccnc1 Show InChI InChI=1S/C26H20N2O3S/c29-26(17-8-20-5-4-18-27-19-20)28-23-11-15-25(16-12-23)32(30,31)24-13-9-22(10-14-24)21-6-2-1-3-7-21/h1-19H,(H,28,29)/b17-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187071 (US9169209, Table 3, Compound 104) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H17ClN2O4S/c1-28-19-10-5-16(22)13-20(19)29(26,27)18-8-6-17(7-9-18)24-21(25)11-4-15-3-2-12-23-14-15/h2-14H,1H3,(H,24,25)/b11-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186988 (US9169209, Table 3, Compound 19) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc(c1)-n1cccn1)\C=C\c1cccnc1 Show InChI InChI=1S/C23H18N4O3S/c28-23(12-7-18-4-2-13-24-17-18)26-19-8-10-21(11-9-19)31(29,30)22-6-1-5-20(16-22)27-15-3-14-25-27/h1-17H,(H,26,28)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187013 (US9169209, Table 3, Compound 45) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc2CCOc12)\C=C\c1cccnc1 Show InChI InChI=1S/C22H18N2O4S/c25-21(11-6-16-3-2-13-23-15-16)24-18-7-9-19(10-8-18)29(26,27)20-5-1-4-17-12-14-28-22(17)20/h1-11,13,15H,12,14H2,(H,24,25)/b11-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187077 (US9169209, Table 3, Compound 110) Show SMILES CN(C)c1ccc(cn1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H20N4O3S/c1-25(2)20-11-10-19(15-23-20)29(27,28)18-8-6-17(7-9-18)24-21(26)12-5-16-4-3-13-22-14-16/h3-15H,1-2H3,(H,24,26)/b12-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186978 (US9169209, Table 3, Compound 9) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1ccc2ncccc2c1)\C=C\c1cccnc1 Show InChI InChI=1S/C23H17N3O3S/c27-23(12-5-17-3-1-13-24-16-17)26-19-6-8-20(9-7-19)30(28,29)21-10-11-22-18(15-21)4-2-14-25-22/h1-16H,(H,26,27)/b12-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187001 (US9169209, Table 3, Compound 32) Show SMILES CC(C)Oc1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C23H22N2O4S/c1-17(2)29-20-8-12-22(13-9-20)30(27,28)21-10-6-19(7-11-21)25-23(26)14-5-18-4-3-15-24-16-18/h3-17H,1-2H3,(H,25,26)/b14-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187038 (US9169209, Table 3, Compound 71) Show SMILES CCCOc1ccc(cc1Cl)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C23H21ClN2O4S/c1-2-14-30-22-11-10-20(15-21(22)24)31(28,29)19-8-6-18(7-9-19)26-23(27)12-5-17-4-3-13-25-16-17/h3-13,15-16H,2,14H2,1H3,(H,26,27)/b12-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187036 (US9169209, Table 3, Compound 69) Show SMILES COc1ccc(cc1Cl)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H17ClN2O4S/c1-28-20-10-9-18(13-19(20)22)29(26,27)17-7-5-16(6-8-17)24-21(25)11-4-15-3-2-12-23-14-15/h2-14H,1H3,(H,24,25)/b11-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187083 (US9169209, Table 3, Compound 116) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc(c1)C(=O)NC1CC1)\C=C\c1cccnc1 Show InChI InChI=1S/C24H21N3O4S/c28-23(13-6-17-3-2-14-25-16-17)26-19-9-11-21(12-10-19)32(30,31)22-5-1-4-18(15-22)24(29)27-20-7-8-20/h1-6,9-16,20H,7-8H2,(H,26,28)(H,27,29)/b13-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187021 (US9169209, Table 3, Compound 53) Show SMILES COc1ccc2cc(ccc2c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C25H20N2O4S/c1-31-22-9-5-20-16-24(10-6-19(20)15-22)32(29,30)23-11-7-21(8-12-23)27-25(28)13-4-18-3-2-14-26-17-18/h2-17H,1H3,(H,27,28)/b13-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187041 (US9169209, Table 3, Compound 74) Show SMILES Cc1cc(Cl)cc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H17ClN2O3S/c1-15-11-17(22)13-20(12-15)28(26,27)19-7-5-18(6-8-19)24-21(25)9-4-16-3-2-10-23-14-16/h2-14H,1H3,(H,24,25)/b9-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187067 (US9169209, Table 3, Compound 100) Show SMILES COc1c(C)cc(cc1C)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C23H22N2O4S/c1-16-13-21(14-17(2)23(16)29-3)30(27,28)20-9-7-19(8-10-20)25-22(26)11-6-18-5-4-12-24-15-18/h4-15H,1-3H3,(H,25,26)/b11-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187078 (US9169209, Table 3, Compound 111) Show SMILES F\C(=C/c1cccnc1)C(=O)Nc1ccc(cc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C20H15FN2O3S/c21-19(13-15-5-4-12-22-14-15)20(24)23-16-8-10-18(11-9-16)27(25,26)17-6-2-1-3-7-17/h1-14H,(H,23,24)/b19-13-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187025 (US9169209, Table 3, Compound 58) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc2Sc3ccccc3Oc12)\C=C\c1cccnc1 Show InChI InChI=1S/C26H18N2O4S2/c29-25(15-10-18-5-4-16-27-17-18)28-19-11-13-20(14-12-19)34(30,31)24-9-3-8-23-26(24)32-21-6-1-2-7-22(21)33-23/h1-17H,(H,28,29)/b15-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187084 (US9169209, Table 3, Compound 117) Show SMILES CCNC(=O)c1cccc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C23H21N3O4S/c1-2-25-23(28)18-6-3-7-21(15-18)31(29,30)20-11-9-19(10-12-20)26-22(27)13-8-17-5-4-14-24-16-17/h3-16H,2H2,1H3,(H,25,28)(H,26,27)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187059 (US9169209, Table 3, Compound 92) Show SMILES COc1cc(Cl)ccc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H17ClN2O4S/c1-28-19-13-16(22)5-10-20(19)29(26,27)18-8-6-17(7-9-18)24-21(25)11-4-15-3-2-12-23-14-15/h2-14H,1H3,(H,24,25)/b11-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187073 (US9169209, Table 3, Compound 106) Show SMILES Cc1ccc(F)cc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H17FN2O3S/c1-15-4-6-17(22)13-20(15)28(26,27)19-9-7-18(8-10-19)24-21(25)11-5-16-3-2-12-23-14-16/h2-14H,1H3,(H,24,25)/b11-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.40	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187052 (US9169209, Table 3, Compound 85) Show SMILES CS(=O)(=O)Nc1cccc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H19N3O5S2/c1-30(26,27)24-18-5-2-6-20(14-18)31(28,29)19-10-8-17(9-11-19)23-21(25)12-7-16-4-3-13-22-15-16/h2-15,24H,1H3,(H,23,25)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.5	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186992 (US9169209, Table 3, Compound 23) Show SMILES COCc1cccc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H20N2O4S/c1-28-16-18-4-2-6-21(14-18)29(26,27)20-10-8-19(9-11-20)24-22(25)12-7-17-5-3-13-23-15-17/h2-15H,16H2,1H3,(H,24,25)/b12-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187029 (US9169209, Table 3, Compound 62) Show SMILES COc1ccccc1S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H18N2O4S/c1-27-19-6-2-3-7-20(19)28(25,26)18-11-9-17(10-12-18)23-21(24)13-8-16-5-4-14-22-15-16/h2-15H,1H3,(H,23,24)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187011 (US9169209, Table 3, Compound 43) Show SMILES Cn1cc(cn1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C18H16N4O3S/c1-22-13-17(12-20-22)26(24,25)16-7-5-15(6-8-16)21-18(23)9-4-14-3-2-10-19-11-14/h2-13H,1H3,(H,21,23)/b9-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186999 (US9169209, Table 3, Compound 30) Show SMILES CCOCc1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C23H22N2O4S/c1-2-29-17-19-5-10-21(11-6-19)30(27,28)22-12-8-20(9-13-22)25-23(26)14-7-18-4-3-15-24-16-18/h3-16H,2,17H2,1H3,(H,25,26)/b14-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.80	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187074 (US9169209, Table 3, Compound 107) Show SMILES CN(C)c1ncc(cn1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C20H19N5O3S/c1-25(2)20-22-13-18(14-23-20)29(27,28)17-8-6-16(7-9-17)24-19(26)10-5-15-4-3-11-21-12-15/h3-14H,1-2H3,(H,24,26)/b10-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.90	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187043 (US9169209, Table 3, Compound 76) Show SMILES CCS(=O)(=O)Nc1cccc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C22H21N3O5S2/c1-2-31(27,28)25-19-6-3-7-21(15-19)32(29,30)20-11-9-18(10-12-20)24-22(26)13-8-17-5-4-14-23-16-17/h3-16,25H,2H2,1H3,(H,24,26)/b13-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.10	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM186996 (US9169209, Table 3, Compound 27) Show SMILES FC(F)(F)c1cc(Cl)cc(c1)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H14ClF3N2O3S/c22-16-10-15(21(23,24)25)11-19(12-16)31(29,30)18-6-4-17(5-7-18)27-20(28)8-3-14-2-1-9-26-13-14/h1-13H,(H,27,28)/b8-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.10	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187006 (US9169209, Table 3, Compound 38) Show SMILES O=C(Nc1ccc(cc1)S(=O)(=O)c1cccc2cc[nH]c12)\C=C\c1cccnc1 Show InChI InChI=1S/C22H17N3O3S/c26-21(11-6-16-3-2-13-23-15-16)25-18-7-9-19(10-8-18)29(27,28)20-5-1-4-17-12-14-24-22(17)20/h1-15,24H,(H,25,26)/b11-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.40	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM187037 (US9169209, Table 3, Compound 70) Show SMILES Cc1ccc(cc1Cl)S(=O)(=O)c1ccc(NC(=O)\C=C\c2cccnc2)cc1 Show InChI InChI=1S/C21H17ClN2O3S/c1-15-4-8-19(13-20(15)22)28(26,27)18-9-6-17(7-10-18)24-21(25)11-5-16-3-2-12-23-14-16/h2-14H,1H3,(H,24,25)/b11-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	7.5	25
FORMA TM, LLC US Patent					Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...				US Patent US9169209 (2015) BindingDB Entry DOI: 10.7270/Q28G8JH9
					More data for this Ligand-Target Pair

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