Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB | n/a | n/a | 6.16 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | n/a | n/a | 4.94E+3 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225274 (2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 5.18E+3 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225276 (2-[4-(4-Benzylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 5.22E+3 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225280 (5-Methoxy-2-[4-(4-benzylpiperazin-1-yl)phenyl]-1H-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225273 (2-[4-(4-Methylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 1.57E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225277 (5-Methoxy-2-[4-(4-methylpiperazin-1-yl)phenyl]-1H-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225278 (5-Methoxy-2-[4-(4-ethylpiperazin-1-yl)phenyl]-1H-b...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.02E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225274 (2-[4-(4-Ethylpiperazin-1-yl)phenyl]-1H-benzo[d]imi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3.49E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225276 (2-[4-(4-Benzylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 9.72E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225275 (2-[4-(4-Phenylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225275 (2-[4-(4-Phenylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxylic ester hydrolase (Equus caballus (Horse)) | BDBM225279 (5-Methoxy-2-[4-(4-phenylpiperazin-1-yl)phenyl]-1H-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225279 (5-Methoxy-2-[4-(4-phenylpiperazin-1-yl)phenyl]-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225273 (2-[4-(4-Methylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | n/a | n/a | 1.17E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225278 (5-Methoxy-2-[4-(4-ethylpiperazin-1-yl)phenyl]-1H-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.21E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225280 (5-Methoxy-2-[4-(4-benzylpiperazin-1-yl)phenyl]-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 1.44E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM225277 (5-Methoxy-2-[4-(4-methylpiperazin-1-yl)phenyl]-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.29E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 | |
Hacettepe University | Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf... | Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK | |||||||||||
More data for this Ligand-Target Pair |