Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article | n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determined | Bioorg Med Chem Lett 5: 163-166 (1995) Article DOI: 10.1016/0960-894X(94)00478-X BindingDB Entry DOI: 10.7270/Q22R3RM4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM1518 (2-ethyl-9-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determined | Bioorg Med Chem Lett 5: 163-166 (1995) Article DOI: 10.1016/0960-894X(94)00478-X BindingDB Entry DOI: 10.7270/Q22R3RM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50285362 (5-Ethyl-11-methyl-5,11-dihydro-3,5,6,11-tetraaza-d...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determined | Bioorg Med Chem Lett 5: 163-166 (1995) Article DOI: 10.1016/0960-894X(94)00478-X BindingDB Entry DOI: 10.7270/Q22R3RM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50285359 (5-Ethyl-11-methyl-5,11-dihydro-1,5,6,11-tetraaza-d...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determined | Bioorg Med Chem Lett 5: 163-166 (1995) Article DOI: 10.1016/0960-894X(94)00478-X BindingDB Entry DOI: 10.7270/Q22R3RM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50285361 (5-Ethyl-11-methyl-5,11-dihydro-2,5,6,11-tetraaza-d...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determined | Bioorg Med Chem Lett 5: 163-166 (1995) Article DOI: 10.1016/0960-894X(94)00478-X BindingDB Entry DOI: 10.7270/Q22R3RM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50285360 (5-Ethyl-10-methyl-5,10-dihydro-3,5,6,10-tetraaza-d...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase(RT) was determined | Bioorg Med Chem Lett 5: 163-166 (1995) Article DOI: 10.1016/0960-894X(94)00478-X BindingDB Entry DOI: 10.7270/Q22R3RM4 | |||||||||||
More data for this Ligand-Target Pair |