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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Agonist activity assessed by stimulation of [35S]GTP-gamma-S binding to human 5HT1A receptor expressed in CHO cells | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to 5HT2B receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to alpha 2C adrenergic receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to sigma1 opioid receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 228 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to 5HT1B receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to alpha 2A adrenergic receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 328 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to 5HT7 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-1B adrenergic receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 378 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to alpha 1B adrenergic receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 413 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to alpha 1A adrenergic receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H1 receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 839 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to histamine H1 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to 5HT2A receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H2 receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to histamine H2 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to D2 dopamine receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H3 receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to histamine H3 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to NET by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Adenosine receptor A2a (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to adenosine A4 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to D5 dopamine receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to 5HT5A receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1E (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to 5HT1E receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to KOR by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tumor necrosis factor receptor superfamily member 16 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to NT by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Adenosine receptor A1 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to adenosine A1 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to SERT by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to adenosine A3 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to hERG by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to 5HT6 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to DAT by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Histamine H4 receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to histamine H4 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to MDR1 by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to D4 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to D3 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to DOR by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Adenosine receptor A2a/A2b (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to adenosine A2 receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Translocator protein (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to BZP receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Binding affinity to M receptor by radioligand binding assay | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50182020 (2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Agonist activity assessed by stimulation of [35S]GTPgammaS binding to human 5HT1A receptor expressed in CHO cells | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons Curated by ChEMBL | Assay Description Agonist activity assessed by stimulation of [35S]GTPgammaS binding to human 5HT1A receptor expressed in CHO cells | Bioorg Med Chem Lett 16: 2101-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.052 BindingDB Entry DOI: 10.7270/Q2ZC82FS | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
