BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 50025876
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50247490 (4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...) Show SMILES CCCCCCOc1ccc(cc1)C(CC(O)=O)C(N)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid \| CH...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50247490 (4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...) Show SMILES CCCCCCOc1ccc(cc1)C(CC(O)=O)C(N)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP8 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM40467 (2-[(4-chlorobenzyl)thio]-1,5,6,7-tetrahydrocyclope...) Show SMILES Clc1ccc(CSc2nc3CCCc3c(=O)[nH]2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM40467 (2-[(4-chlorobenzyl)thio]-1,5,6,7-tetrahydrocyclope...) Show SMILES Clc1ccc(CSc2nc3CCCc3c(=O)[nH]2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid \| CH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP8 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50247490 (4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...) Show SMILES CCCCCCOc1ccc(cc1)C(CC(O)=O)C(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM40478 (2-[(4-methoxyphenyl)methylsulfanyl]-6-methyl-1H-py...) Show SMILES COc1ccc(CSc2nc(C)cc(=O)[nH]2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid \| CH...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50247207 (2-(biphenyl-4-ylsulfonamido)pentanedioic acid \| CH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM40478 (2-[(4-methoxyphenyl)methylsulfanyl]-6-methyl-1H-py...) Show SMILES COc1ccc(CSc2nc(C)cc(=O)[nH]2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50247490 (4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid ...) Show SMILES CCCCCCOc1ccc(cc1)C(CC(O)=O)C(N)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM40478 (2-[(4-methoxyphenyl)methylsulfanyl]-6-methyl-1H-py...) Show SMILES COc1ccc(CSc2nc(C)cc(=O)[nH]2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP8 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM40467 (2-[(4-chlorobenzyl)thio]-1,5,6,7-tetrahydrocyclope...) Show SMILES Clc1ccc(CSc2nc3CCCc3c(=O)[nH]2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM40478 (2-[(4-methoxyphenyl)methylsulfanyl]-6-methyl-1H-py...) Show SMILES COc1ccc(CSc2nc(C)cc(=O)[nH]2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP9 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM40467 (2-[(4-chlorobenzyl)thio]-1,5,6,7-tetrahydrocyclope...) Show SMILES Clc1ccc(CSc2nc3CCCc3c(=O)[nH]2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP8 by fluorogenic substrate assay				Bioorg Med Chem 17: 1101-8 (2009) Article DOI: 10.1016/j.bmc.2008.03.018 BindingDB Entry DOI: 10.7270/Q2XS5V5D
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair