Compile Data Set for Download or QSAR

Found 50 hits Enz. Inhib. hit(s) with all data for entry = 50047593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM260159 (BDBM50177661 | US9504692, Mepezine) Show SMILES CN1CCCC(CN2c3ccccc3Sc3ccccc23)C1 Show InChI InChI=1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of GST-MALT1 (325 to 760 residues) (unknown origin) using Ac-LRSR-AMC as substrate by fluorescence analysis				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM260159 (BDBM50177661 | US9504692, Mepezine) Show SMILES CN1CCCC(CN2c3ccccc3Sc3ccccc23)C1 Show InChI InChI=1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant full length GST-MALT1 (unknown origin) expressed in Escherichia coli using Ac-LRSR-AMC as substrate by fluorescence analysi...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177471 (CHEMBL3813831) Show SMILES COCCOc1nc(-c2ccc(Br)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18BrClN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(20)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-21/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177471 (CHEMBL3813831) Show SMILES COCCOc1nc(-c2ccc(Br)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18BrClN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(20)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-21/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177471 (CHEMBL3813831) Show SMILES COCCOc1nc(-c2ccc(Br)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18BrClN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(20)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-21/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177471 (CHEMBL3813831) Show SMILES COCCOc1nc(-c2ccc(Br)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18BrClN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(20)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-21/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177153 (CHEMBL3814576) Show SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177152 (CHEMBL3814162) Show SMILES COCCOc1nc(-c2ccc(F)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18ClFN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177152 (CHEMBL3814162) Show SMILES COCCOc1nc(-c2ccc(F)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18ClFN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50133332 (CHEMBL3183233) Show SMILES COCCOc1nc(-c2ccc(Cl)c(Cl)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50133332 (CHEMBL3183233) Show SMILES COCCOc1nc(-c2ccc(Cl)c(Cl)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177152 (CHEMBL3814162) Show SMILES COCCOc1nc(-c2ccc(F)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18ClFN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177152 (CHEMBL3814162) Show SMILES COCCOc1nc(-c2ccc(F)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18ClFN4O3/c1-27-10-11-28-19-23-18(13-2-4-14(21)5-3-13)25(24-19)16-8-6-15(7-9-16)22-17(26)12-20/h2-9H,10-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177222 (CHEMBL3814883) Show SMILES COCCOc1nc(-c2ccc(OC)c(OC)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C21H23ClN4O5/c1-28-10-11-31-21-24-20(14-4-9-17(29-2)18(12-14)30-3)26(25-21)16-7-5-15(6-8-16)23-19(27)13-22/h4-9,12H,10-11,13H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177222 (CHEMBL3814883) Show SMILES COCCOc1nc(-c2ccc(OC)c(OC)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C21H23ClN4O5/c1-28-10-11-31-21-24-20(14-4-9-17(29-2)18(12-14)30-3)26(25-21)16-7-5-15(6-8-16)23-19(27)13-22/h4-9,12H,10-11,13H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177221 (CHEMBL3814599) Show SMILES COCCOc1nc(-c2ccc(C)c(C)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C21H23ClN4O3/c1-14-4-5-16(12-15(14)2)20-24-21(29-11-10-28-3)25-26(20)18-8-6-17(7-9-18)23-19(27)13-22/h4-9,12H,10-11,13H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177221 (CHEMBL3814599) Show SMILES COCCOc1nc(-c2ccc(C)c(C)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C21H23ClN4O3/c1-14-4-5-16(12-15(14)2)20-24-21(29-11-10-28-3)25-26(20)18-8-6-17(7-9-18)23-19(27)13-22/h4-9,12H,10-11,13H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177470 (CHEMBL3813708) Show SMILES COCCOc1nc(-c2cccc(Br)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18BrClN4O3/c1-27-9-10-28-19-23-18(13-3-2-4-14(20)11-13)25(24-19)16-7-5-15(6-8-16)22-17(26)12-21/h2-8,11H,9-10,12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177470 (CHEMBL3813708) Show SMILES COCCOc1nc(-c2cccc(Br)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18BrClN4O3/c1-27-9-10-28-19-23-18(13-3-2-4-14(20)11-13)25(24-19)16-7-5-15(6-8-16)22-17(26)12-21/h2-8,11H,9-10,12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177224 (CHEMBL3814955) Show SMILES COCCOc1nc(-c2ccc(cc2)-c2ccccc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C25H23ClN4O3/c1-32-15-16-33-25-28-24(20-9-7-19(8-10-20)18-5-3-2-4-6-18)30(29-25)22-13-11-21(12-14-22)27-23(31)17-26/h2-14H,15-17H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177276 (CHEMBL3814394) Show SMILES COCCOc1nc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H18ClF3N4O3/c1-30-10-11-31-19-26-18(13-2-4-14(5-3-13)20(22,23)24)28(27-19)16-8-6-15(7-9-16)25-17(29)12-21/h2-9H,10-12H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177224 (CHEMBL3814955) Show SMILES COCCOc1nc(-c2ccc(cc2)-c2ccccc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C25H23ClN4O3/c1-32-15-16-33-25-28-24(20-9-7-19(8-10-20)18-5-3-2-4-6-18)30(29-25)22-13-11-21(12-14-22)27-23(31)17-26/h2-14H,15-17H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177276 (CHEMBL3814394) Show SMILES COCCOc1nc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H18ClF3N4O3/c1-30-10-11-31-19-26-18(13-2-4-14(5-3-13)20(22,23)24)28(27-19)16-8-6-15(7-9-16)25-17(29)12-21/h2-9H,10-12H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177223 (CHEMBL3813977) Show SMILES COCCOc1nc(-c2ccc(F)c(F)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H17ClF2N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177223 (CHEMBL3813977) Show SMILES COCCOc1nc(-c2ccc(F)c(F)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H17ClF2N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177596 (CHEMBL3813764) Show SMILES COCCOc1nc(-c2cccc(Cl)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-9-10-28-19-23-18(13-3-2-4-14(21)11-13)25(24-19)16-7-5-15(6-8-16)22-17(26)12-20/h2-8,11H,9-10,12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177596 (CHEMBL3813764) Show SMILES COCCOc1nc(-c2cccc(Cl)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18Cl2N4O3/c1-27-9-10-28-19-23-18(13-3-2-4-14(21)11-13)25(24-19)16-7-5-15(6-8-16)22-17(26)12-20/h2-8,11H,9-10,12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177154 (CHEMBL3814060) Show SMILES COCCOc1nc(-c2ccc(Cl)c(Cl)c2)n(n1)-c1ccc(NC(=O)C=C)cc1 Show InChI InChI=1S/C20H18Cl2N4O3/c1-3-18(27)23-14-5-7-15(8-6-14)26-19(13-4-9-16(21)17(22)12-13)24-20(25-26)29-11-10-28-2/h3-9,12H,1,10-11H2,2H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177154 (CHEMBL3814060) Show SMILES COCCOc1nc(-c2ccc(Cl)c(Cl)c2)n(n1)-c1ccc(NC(=O)C=C)cc1 Show InChI InChI=1S/C20H18Cl2N4O3/c1-3-18(27)23-14-5-7-15(8-6-14)26-19(13-4-9-16(21)17(22)12-13)24-20(25-26)29-11-10-28-2/h3-9,12H,1,10-11H2,2H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177469 (CHEMBL3814068) Show SMILES COCCOc1nc(-c2ccc(OC)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O4/c1-27-11-12-29-20-23-19(14-3-9-17(28-2)10-4-14)25(24-20)16-7-5-15(6-8-16)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177469 (CHEMBL3814068) Show SMILES COCCOc1nc(-c2ccc(OC)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O4/c1-27-11-12-29-20-23-19(14-3-9-17(28-2)10-4-14)25(24-20)16-7-5-15(6-8-16)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177169 (CHEMBL3815024) Show SMILES COCCOc1nc(-c2ccc3OCOc3c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H19ClN4O5/c1-27-8-9-28-20-23-19(13-2-7-16-17(10-13)30-12-29-16)25(24-20)15-5-3-14(4-6-15)22-18(26)11-21/h2-7,10H,8-9,11-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177590 (CHEMBL3814299) Show SMILES COCCOc1nc(-c2cccc(F)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18ClFN4O3/c1-27-9-10-28-19-23-18(13-3-2-4-14(21)11-13)25(24-19)16-7-5-15(6-8-16)22-17(26)12-20/h2-8,11H,9-10,12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177169 (CHEMBL3815024) Show SMILES COCCOc1nc(-c2ccc3OCOc3c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H19ClN4O5/c1-27-8-9-28-20-23-19(13-2-7-16-17(10-13)30-12-29-16)25(24-20)15-5-3-14(4-6-15)22-18(26)11-21/h2-7,10H,8-9,11-12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177590 (CHEMBL3814299) Show SMILES COCCOc1nc(-c2cccc(F)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H18ClFN4O3/c1-27-9-10-28-19-23-18(13-3-2-4-14(21)11-13)25(24-19)16-7-5-15(6-8-16)22-17(26)12-20/h2-8,11H,9-10,12H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177227 (CHEMBL3814547) Show SMILES COCCOc1nc(-c2cccc(c2)C(F)(F)F)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H18ClF3N4O3/c1-30-9-10-31-19-26-18(13-3-2-4-14(11-13)20(22,23)24)28(27-19)16-7-5-15(6-8-16)25-17(29)12-21/h2-8,11H,9-10,12H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177227 (CHEMBL3814547) Show SMILES COCCOc1nc(-c2cccc(c2)C(F)(F)F)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H18ClF3N4O3/c1-30-9-10-31-19-26-18(13-3-2-4-14(11-13)20(22,23)24)28(27-19)16-7-5-15(6-8-16)25-17(29)12-21/h2-8,11H,9-10,12H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177650 (CHEMBL3814679) Show SMILES COCCOc1nc(-c2ccccc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H19ClN4O3/c1-26-11-12-27-19-22-18(14-5-3-2-4-6-14)24(23-19)16-9-7-15(8-10-16)21-17(25)13-20/h2-10H,11-13H2,1H3,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177650 (CHEMBL3814679) Show SMILES COCCOc1nc(-c2ccccc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C19H19ClN4O3/c1-26-11-12-27-19-22-18(14-5-3-2-4-6-14)24(23-19)16-9-7-15(8-10-16)21-17(25)13-20/h2-10H,11-13H2,1H3,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177468 (CHEMBL3814540) Show SMILES COCCOc1nc(-c2cccc(OC)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O4/c1-27-10-11-29-20-23-19(14-4-3-5-17(12-14)28-2)25(24-20)16-8-6-15(7-9-16)22-18(26)13-21/h3-9,12H,10-11,13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177468 (CHEMBL3814540) Show SMILES COCCOc1nc(-c2cccc(OC)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O4/c1-27-10-11-29-20-23-19(14-4-3-5-17(12-14)28-2)25(24-20)16-8-6-15(7-9-16)22-18(26)13-21/h3-9,12H,10-11,13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177225 (CHEMBL3814081) Show SMILES COCCOc1nc(-c2cccc(C)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-4-3-5-15(12-14)19-23-20(28-11-10-27-2)24-25(19)17-8-6-16(7-9-17)22-18(26)13-21/h3-9,12H,10-11,13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177225 (CHEMBL3814081) Show SMILES COCCOc1nc(-c2cccc(C)c2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-4-3-5-15(12-14)19-23-20(28-11-10-27-2)24-25(19)17-8-6-16(7-9-17)22-18(26)13-21/h3-9,12H,10-11,13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.78E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) Article DOI: 10.1016/j.bmc.2016.03.035 BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair