Found 34 hits Enz. Inhib. hit(s) with all data for entry = 50031122 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307501
((6S)-N,N-dipropyl-5,6,7,8-tetrahydro-1,1'-binaphth...)Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1cccc2ccccc12 |r| Show InChI InChI=1S/C26H31N/c1-3-17-27(18-4-2)22-15-16-24-21(19-22)11-8-14-26(24)25-13-7-10-20-9-5-6-12-23(20)25/h5-14,22H,3-4,15-19H2,1-2H3/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50139351
(2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...)Show InChI InChI=1S/C15H24N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h6,9-10,13H,3-5,7-8,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50150684
((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...)Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](COc12)N(C)C |wD:16.22,(-5.36,2.24,;-4,1.49,;-2.67,2.28,;-2.7,3.82,;-1.37,4.59,;,3.84,;,2.29,;1.31,1.53,;2.64,2.29,;-1.34,1.53,;-1.34,-.01,;-2.67,-.78,;-2.67,-2.32,;-1.34,-3.09,;,-2.34,;1.31,-3.13,;2.67,-2.34,;2.67,-.78,;1.31,-.01,;,-.78,;4,-3.13,;4,-4.66,;5.35,-2.34,)| Show InChI InChI=1S/C19H23NO3/c1-20(2)14-11-13-7-5-8-15(19(13)23-12-14)18-16(21-3)9-6-10-17(18)22-4/h5-10,14H,11-12H2,1-4H3/t14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50150685
(((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)Show InChI InChI=1S/C22H29N/c1-3-15-23(16-4-2)20-13-14-22-19(17-20)11-8-12-21(22)18-9-6-5-7-10-18/h5-12,20H,3-4,13-17H2,1-2H3/t20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50150676
(((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...)Show InChI InChI=1S/C21H27NO/c1-3-13-22(14-4-2)19-15-18-11-8-12-20(21(18)23-16-19)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3/t19-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50139355
(2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...)Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50210123
(CHEMBL395870 | N,N-dimethyl-2-(2'-methylbiphenyl-3...)Show InChI InChI=1S/C17H21N/c1-14-7-4-5-10-17(14)16-9-6-8-15(13-16)11-12-18(2)3/h4-10,13H,11-12H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50139357
(CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...)Show InChI InChI=1S/C13H16N2S2/c1-15(2)8-9-16-13-14-12(10-17-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50160366
((S)-6-(2,6-dimethylphenyl)-N,N-dimethylchroman-3-a...)Show InChI InChI=1S/C19H23NO/c1-13-6-5-7-14(2)19(13)15-8-9-18-16(10-15)11-17(12-21-18)20(3)4/h5-10,17H,11-12H2,1-4H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 13.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307490
(2-(6-(Furan-3-yl)pyridin-2-yloxy)-N,N-dimethyl-eth...)Show InChI InChI=1S/C13H16N2OS/c1-15(2)7-9-17-13-5-3-4-12(14-13)11-6-8-16-10-11/h3-6,8,10H,7,9H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50307490
(2-(6-(Furan-3-yl)pyridin-2-yloxy)-N,N-dimethyl-eth...)Show InChI InChI=1S/C13H16N2OS/c1-15(2)7-9-17-13-5-3-4-12(14-13)11-6-8-16-10-11/h3-6,8,10H,7,9H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50139361
(2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...)Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50139355
(2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...)Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307488
(2-(6-(2,6-Dimethylphenyl)pyridin-2-ylthio)-N,Ndime...)Show InChI InChI=1S/C17H22N2S/c1-13-7-5-8-14(2)17(13)15-9-6-10-16(18-15)20-12-11-19(3)4/h5-10H,11-12H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 128 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50139361
(2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...)Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 133 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307494
(2-(Biphenyl-2-yloxy)-N,N-dimethylethanamine | CHEM...)Show InChI InChI=1S/C16H19NO/c1-17(2)12-13-18-16-11-7-6-10-15(16)14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 156 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50307504
(2-(Biphenyl-3-ylthio)-N,N-dimethylethanamine | CHE...)Show InChI InChI=1S/C16H19NS/c1-17(2)11-12-18-16-10-6-9-15(13-16)14-7-4-3-5-8-14/h3-10,13H,11-12H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 516 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307493
(2-(Biphenyl-2-ylthio)-N,N-dimethylethanamine | CHE...)Show InChI InChI=1S/C16H19NS/c1-17(2)12-13-18-16-11-7-6-10-15(16)14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 553 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307495
(2-(2'-Methoxybiphenyl-2-yloxy)-N,N-dimethyl-ethana...)Show InChI InChI=1S/C17H21NO2/c1-18(2)12-13-20-17-11-7-5-9-15(17)14-8-4-6-10-16(14)19-3/h4-11H,12-13H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 669 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50307505
(2-(3-Bromophenylthio)-N,N-dimethylethanamine | CHE...)Show InChI InChI=1S/C10H14BrNS/c1-12(2)6-7-13-10-5-3-4-9(11)8-10/h3-5,8H,6-7H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 676 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50307487
(2-(6-Bromopyridin-2-yloxy)-N,N-dimethylethan-amine...)Show InChI InChI=1S/C9H13BrN2O/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 902 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50307488
(2-(6-(2,6-Dimethylphenyl)pyridin-2-ylthio)-N,Ndime...)Show InChI InChI=1S/C17H22N2S/c1-13-7-5-8-14(2)17(13)15-9-6-10-16(18-15)20-12-11-19(3)4/h5-10H,11-12H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 927 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307496
(2-(2',6'-dimethylbiphenyl-2-ylthio)-N,N-dimethylet...)Show SMILES CN(C)CCSc1ccccc1-c1c(C)cccc1C |(37.51,-41.59,;36.18,-40.82,;36.18,-39.28,;34.85,-41.59,;33.51,-40.82,;32.18,-41.59,;30.85,-40.83,;30.85,-39.28,;29.51,-38.51,;28.18,-39.28,;28.18,-40.83,;29.51,-41.6,;29.52,-43.13,;30.85,-43.9,;32.18,-43.13,;30.85,-45.43,;29.51,-46.21,;28.18,-45.44,;28.18,-43.9,;26.85,-43.13,)| Show InChI InChI=1S/C18H23NS/c1-14-8-7-9-15(2)18(14)16-10-5-6-11-17(16)20-13-12-19(3)4/h5-11H,12-13H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307500
(2-(4-(2,6-Dimethoxyphenyl)pyrimidin-2-yl)-N,Ndimet...)Show InChI InChI=1S/C16H21N3O2/c1-19(2)11-9-15-17-10-8-12(18-15)16-13(20-3)6-5-7-14(16)21-4/h5-8,10H,9,11H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307489
(2-(6-(2,6-Dimethylphenyl)pyridin-2-yloxy)-N,Ndimet...)Show InChI InChI=1S/C17H22N2O/c1-13-7-5-8-14(2)17(13)15-9-6-10-16(18-15)20-12-11-19(3)4/h5-10H,11-12H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307487
(2-(6-Bromopyridin-2-yloxy)-N,N-dimethylethan-amine...)Show InChI InChI=1S/C9H13BrN2O/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50307503
(2-(2,6-Dimethylbiphenyl-3-ylthio)-N,N-dimethyl eth...)Show InChI InChI=1S/C18H23NS/c1-14-7-5-8-15(2)18(14)16-9-6-10-17(13-16)20-12-11-19(3)4/h5-10,13H,11-12H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307492
(2-(2-Bromophenoxy)-N,N-dimethylethanamine | CHEMBL...)Show InChI InChI=1S/C10H14BrNO/c1-12(2)7-8-13-10-6-4-3-5-9(10)11/h3-6H,7-8H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| 2.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307491
(2-(2-Bromophenylthio)-N,N-dimethylethanamine | CHE...)Show InChI InChI=1S/C10H14BrNS/c1-12(2)7-8-13-10-6-4-3-5-9(10)11/h3-6H,7-8H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 4.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50307489
(2-(6-(2,6-Dimethylphenyl)pyridin-2-yloxy)-N,Ndimet...)Show InChI InChI=1S/C17H22N2O/c1-13-7-5-8-14(2)17(13)15-9-6-10-16(18-15)20-12-11-19(3)4/h5-10H,11-12H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307499
(2-(5-(2,6-Dimethoxyphenyl)-1,2,4-triazin-3-yl)-N,N...)Show InChI InChI=1S/C15H20N4O2/c1-19(2)9-8-14-17-11(10-16-18-14)15-12(20-3)6-5-7-13(15)21-4/h5-7,10H,8-9H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307498
(2-(5-(2,6-Dimethylphenyl)-1,2,4-triazin-3-yl)-N,Nd...)Show InChI InChI=1S/C15H20N4/c1-11-6-5-7-12(2)15(11)13-10-16-18-14(17-13)8-9-19(3)4/h5-7,10H,8-9H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307497
(CHEMBL603062 | N,N-Dimethyl-2-(5-phenyl-1,2,4-tria...)Show InChI InChI=1S/C13H16N4/c1-17(2)9-8-13-15-12(10-14-16-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50307502
(7-(2,6-dimethylphenyl)-N,N-dimethylchroman-3-amine...)Show InChI InChI=1S/C19H23NO/c1-13-6-5-7-14(2)19(13)16-9-8-15-10-17(20(3)4)12-21-18(15)11-16/h5-9,11,17H,10,12H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans
Curated by ChEMBL
| Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells |
Bioorg Med Chem 18: 1958-67 (2010)
Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 |
More data for this Ligand-Target Pair | |