Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315219 (1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315047 (1-(4-(4,6-di(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315209 (1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315212 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-6-(3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315216 (1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315218 (1-cyclopropyl-3-(4-(4,6-di(8-oxa-3-azabicyclo[3.2....) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315217 (1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315211 (1-(4-(4,6-di((1S,4S)-2-oxa-5-azabicyclo[2.2.1]hept...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315214 (3,3'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315213 (2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315215 (3-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase mTOR (Rattus norvegicus) | BDBM50315210 (1-(4-(4,6-di((1R,4R)-2-oxa-5-azabicyclo[2.2.1]hept...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA | Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X | |||||||||||
More data for this Ligand-Target Pair |