Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM22418 (Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM22418 (Cocaine | Cocaine (-) | methyl (1R,2R,3S,5S)-3-(be...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50366600 (CHEMBL301281) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50366600 (CHEMBL301281) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078779 ((2R,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078779 ((2R,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078779 ((2R,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078779 ((2R,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50005560 (3-Benzoyloxy-8-methyl-8-azonia-bicyclo[3.2.1]octan...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | PubMed | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50005560 (3-Benzoyloxy-8-methyl-8-azonia-bicyclo[3.2.1]octan...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | PubMed | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078778 ((2R,3R)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078782 ((2S,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078782 ((2S,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078778 ((2R,3R)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078781 ((2S,3R)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078781 ((2S,3R)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078782 ((2S,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50078782 ((2S,3S)-3-Benzoyloxy-8-oxa-bicyclo[3.2.1]octane-2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair |