Found 126 hits Enz. Inhib. hit(s) with all data for entry = 50014373 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141595
((E)-3-{4-[3,5-Di-tert-butyl-2-(3-fluoro-propoxy)-p...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCCCF)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H35FO3S/c1-18(14-26(31)32)25-17-21-20(10-8-11-24(21)34-25)22-15-19(28(2,3)4)16-23(29(5,6)7)27(22)33-13-9-12-30/h8,10-11,14-17H,9,12-13H2,1-7H3,(H,31,32)/b18-14+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Antagonist activity for Retinoic X receptor alpha in CV1 cells |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141599
((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2,2-trifluoro-eth...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCC(F)(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C28H31F3O3S/c1-16(11-24(32)33)23-14-19-18(9-8-10-22(19)35-23)20-12-17(26(2,3)4)13-21(27(5,6)7)25(20)34-15-28(29,30)31/h8-14H,15H2,1-7H3,(H,32,33)/b16-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50032671
(6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPH...)Show SMILES Cc1cc2c(cc1C1(CC1)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141600
((Z)-3-{7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C(/F)C(O)=O Show InChI InChI=1S/C26H27F3O4/c1-13(2)17-9-19(14(3)4)25(32-12-22(27)28)20(10-17)18-8-6-7-16-11-21(33-24(16)18)15(5)23(29)26(30)31/h6-11,13-14,22H,12H2,1-5H3,(H,30,31)/b23-15- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141591
((E)-3-[4-(3,5-Di-tert-butyl-2-heptyloxy-phenyl)-be...)Show SMILES CCCCCCCOc1c(cc(cc1C(C)(C)C)C(C)(C)C)-c1cccc2sc(cc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C33H44O3S/c1-9-10-11-12-13-17-36-31-26(19-23(32(3,4)5)20-27(31)33(6,7)8)24-15-14-16-28-25(24)21-29(37-28)22(2)18-30(34)35/h14-16,18-21H,9-13,17H2,1-8H3,(H,34,35)/b22-18+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141590
((E)-3-[4-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...)Show SMILES CCOc1c(cc(cc1-c1cccc2sc(cc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C26H30O3S/c1-7-29-26-20(16(4)5)12-18(15(2)3)13-22(26)19-9-8-10-23-21(19)14-24(30-23)17(6)11-25(27)28/h8-16H,7H2,1-6H3,(H,27,28)/b17-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141592
((E)-3-[4-(3,5-Di-tert-butyl-2-methyl-phenyl)-benzo...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1C)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C27H32O2S/c1-16(12-25(28)29)24-15-21-19(10-9-11-23(21)30-24)20-13-18(26(3,4)5)14-22(17(20)2)27(6,7)8/h9-15H,1-8H3,(H,28,29)/b16-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Antagonist activity for Retinoic X receptor alpha in CV1 cells |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141597
((E)-3-{4-[3,5-Di-tert-butyl-2-(3,3-difluoro-propox...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCCC(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H34F2O3S/c1-17(13-26(32)33)24-16-20-19(9-8-10-23(20)35-24)21-14-18(28(2,3)4)15-22(29(5,6)7)27(21)34-12-11-25(30)31/h8-10,13-16,25H,11-12H2,1-7H3,(H,32,33)/b17-13+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Antagonist activity for Retinoic X receptor alpha in CV1 cells |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50032671
(6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPH...)Show SMILES Cc1cc2c(cc1C1(CC1)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB Article PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141599
((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2,2-trifluoro-eth...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCC(F)(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C28H31F3O3S/c1-16(11-24(32)33)23-14-19-18(9-8-10-22(19)35-23)20-12-17(26(2,3)4)13-21(27(5,6)7)25(20)34-15-28(29,30)31/h8-14H,15H2,1-7H3,(H,32,33)/b16-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141595
((E)-3-{4-[3,5-Di-tert-butyl-2-(3-fluoro-propoxy)-p...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCCCF)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H35FO3S/c1-18(14-26(31)32)25-17-21-20(10-8-11-24(21)34-25)22-15-19(28(2,3)4)16-23(29(5,6)7)27(22)33-13-9-12-30/h8,10-11,14-17H,9,12-13H2,1-7H3,(H,31,32)/b18-14+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141590
((E)-3-[4-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...)Show SMILES CCOc1c(cc(cc1-c1cccc2sc(cc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C26H30O3S/c1-7-29-26-20(16(4)5)12-18(15(2)3)13-22(26)19-9-8-10-23-21(19)14-24(30-23)17(6)11-25(27)28/h8-16H,7H2,1-6H3,(H,27,28)/b17-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141590
((E)-3-[4-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...)Show SMILES CCOc1c(cc(cc1-c1cccc2sc(cc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C26H30O3S/c1-7-29-26-20(16(4)5)12-18(15(2)3)13-22(26)19-9-8-10-23-21(19)14-24(30-23)17(6)11-25(27)28/h8-16H,7H2,1-6H3,(H,27,28)/b17-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141596
((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C28H32F2O3S/c1-16(11-25(31)32)23-14-19-18(9-8-10-22(19)34-23)20-12-17(27(2,3)4)13-21(28(5,6)7)26(20)33-15-24(29)30/h8-14,24H,15H2,1-7H3,(H,31,32)/b16-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50452047
(CHEMBL2372524)Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NP(O)(O)=O)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C14H21N4O6P/c1-9(13(20)16-8-12(15)19)17-14(21)11(18-25(22,23)24)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,15,19)(H,16,20)(H,17,21)(H3,18,22,23,24)/t9-,11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141591
((E)-3-[4-(3,5-Di-tert-butyl-2-heptyloxy-phenyl)-be...)Show SMILES CCCCCCCOc1c(cc(cc1C(C)(C)C)C(C)(C)C)-c1cccc2sc(cc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C33H44O3S/c1-9-10-11-12-13-17-36-31-26(19-23(32(3,4)5)20-27(31)33(6,7)8)24-15-14-16-28-25(24)21-29(37-28)22(2)18-30(34)35/h14-16,18-21H,9-13,17H2,1-8H3,(H,34,35)/b22-18+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141597
((E)-3-{4-[3,5-Di-tert-butyl-2-(3,3-difluoro-propox...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCCC(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H34F2O3S/c1-17(13-26(32)33)24-16-20-19(9-8-10-23(20)35-24)21-14-18(28(2,3)4)15-22(29(5,6)7)27(21)34-12-11-25(30)31/h8-10,13-16,25H,11-12H2,1-7H3,(H,32,33)/b17-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50032671
(6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPH...)Show SMILES Cc1cc2c(cc1C1(CC1)c1ccc(cn1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141604
((E)-3-[4-(3,5-Diisopropyl-2-propoxy-phenyl)-benzo[...)Show SMILES CCCOc1c(cc(cc1-c1cccc2sc(cc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C27H32O3S/c1-7-11-30-27-21(17(4)5)13-19(16(2)3)14-23(27)20-9-8-10-24-22(20)15-25(31-24)18(6)12-26(28)29/h8-10,12-17H,7,11H2,1-6H3,(H,28,29)/b18-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141604
((E)-3-[4-(3,5-Diisopropyl-2-propoxy-phenyl)-benzo[...)Show SMILES CCCOc1c(cc(cc1-c1cccc2sc(cc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C27H32O3S/c1-7-11-30-27-21(17(4)5)13-19(16(2)3)14-23(27)20-9-8-10-24-22(20)15-25(31-24)18(6)12-26(28)29/h8-10,12-17H,7,11H2,1-6H3,(H,28,29)/b18-12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141589
((Z)-3-[7-(2-Butoxy-3,5-diisopropyl-phenyl)-benzofu...)Show SMILES CCCCOc1c(cc(cc1-c1cccc2cc(oc12)C(\C)=C(/F)C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C28H33FO4/c1-7-8-12-32-27-22(17(4)5)13-20(16(2)3)14-23(27)21-11-9-10-19-15-24(33-26(19)21)18(6)25(29)28(30)31/h9-11,13-17H,7-8,12H2,1-6H3,(H,30,31)/b25-18- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50129720
((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...)Show SMILES C\C(\C=C\C=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34F2O3/c1-16(12-22(28)29)10-9-11-17(2)19-13-18(24(3,4)5)14-20(25(6,7)8)23(19)30-15-21(26)27/h9-14,21H,15H2,1-8H3,(H,28,29)/b10-9+,16-12+,17-11- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50129720
((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...)Show SMILES C\C(\C=C\C=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34F2O3/c1-16(12-22(28)29)10-9-11-17(2)19-13-18(24(3,4)5)14-20(25(6,7)8)23(19)30-15-21(26)27/h9-14,21H,15H2,1-8H3,(H,28,29)/b10-9+,16-12+,17-11- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50452047
(CHEMBL2372524)Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NP(O)(O)=O)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C14H21N4O6P/c1-9(13(20)16-8-12(15)19)17-14(21)11(18-25(22,23)24)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,15,19)(H,16,20)(H,17,21)(H3,18,22,23,24)/t9-,11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141604
((E)-3-[4-(3,5-Diisopropyl-2-propoxy-phenyl)-benzo[...)Show SMILES CCCOc1c(cc(cc1-c1cccc2sc(cc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C27H32O3S/c1-7-11-30-27-21(17(4)5)13-19(16(2)3)14-23(27)20-9-8-10-24-22(20)15-25(31-24)18(6)12-26(28)29/h8-10,12-17H,7,11H2,1-6H3,(H,28,29)/b18-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141596
((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C28H32F2O3S/c1-16(11-25(31)32)23-14-19-18(9-8-10-22(19)34-23)20-12-17(27(2,3)4)13-21(28(5,6)7)26(20)33-15-24(29)30/h8-14,24H,15H2,1-7H3,(H,31,32)/b16-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141599
((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2,2-trifluoro-eth...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCC(F)(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C28H31F3O3S/c1-16(11-24(32)33)23-14-19-18(9-8-10-22(19)35-23)20-12-17(26(2,3)4)13-21(27(5,6)7)25(20)34-15-28(29,30)31/h8-14H,15H2,1-7H3,(H,32,33)/b16-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141595
((E)-3-{4-[3,5-Di-tert-butyl-2-(3-fluoro-propoxy)-p...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCCCF)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H35FO3S/c1-18(14-26(31)32)25-17-21-20(10-8-11-24(21)34-25)22-15-19(28(2,3)4)16-23(29(5,6)7)27(22)33-13-9-12-30/h8,10-11,14-17H,9,12-13H2,1-7H3,(H,31,32)/b18-14+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141601
((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzofu...)Show SMILES CCOc1c(cc(cc1-c1cccc2cc(oc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C26H30O4/c1-7-29-26-21(16(4)5)12-19(15(2)3)13-22(26)20-10-8-9-18-14-23(30-25(18)20)17(6)11-24(27)28/h8-16H,7H2,1-6H3,(H,27,28)/b17-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141591
((E)-3-[4-(3,5-Di-tert-butyl-2-heptyloxy-phenyl)-be...)Show SMILES CCCCCCCOc1c(cc(cc1C(C)(C)C)C(C)(C)C)-c1cccc2sc(cc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C33H44O3S/c1-9-10-11-12-13-17-36-31-26(19-23(32(3,4)5)20-27(31)33(6,7)8)24-15-14-16-28-25(24)21-29(37-28)22(2)18-30(34)35/h14-16,18-21H,9-13,17H2,1-8H3,(H,34,35)/b22-18+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141589
((Z)-3-[7-(2-Butoxy-3,5-diisopropyl-phenyl)-benzofu...)Show SMILES CCCCOc1c(cc(cc1-c1cccc2cc(oc12)C(\C)=C(/F)C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C28H33FO4/c1-7-8-12-32-27-22(17(4)5)13-20(16(2)3)14-23(27)21-11-9-10-19-15-24(33-26(19)21)18(6)25(29)28(30)31/h9-11,13-17H,7-8,12H2,1-6H3,(H,30,31)/b25-18- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50452047
(CHEMBL2372524)Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NP(O)(O)=O)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C14H21N4O6P/c1-9(13(20)16-8-12(15)19)17-14(21)11(18-25(22,23)24)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3,(H2,15,19)(H,16,20)(H,17,21)(H3,18,22,23,24)/t9-,11-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141592
((E)-3-[4-(3,5-Di-tert-butyl-2-methyl-phenyl)-benzo...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1C)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C27H32O2S/c1-16(12-25(28)29)24-15-21-19(10-9-11-23(21)30-24)20-13-18(26(3,4)5)14-22(17(20)2)27(6,7)8/h9-15H,1-8H3,(H,28,29)/b16-12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141597
((E)-3-{4-[3,5-Di-tert-butyl-2-(3,3-difluoro-propox...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCCC(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C29H34F2O3S/c1-17(13-26(32)33)24-16-20-19(9-8-10-23(20)35-24)21-14-18(28(2,3)4)15-22(29(5,6)7)27(21)34-12-11-25(30)31/h8-10,13-16,25H,11-12H2,1-7H3,(H,32,33)/b17-13+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50129720
((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...)Show SMILES C\C(\C=C\C=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34F2O3/c1-16(12-22(28)29)10-9-11-17(2)19-13-18(24(3,4)5)14-20(25(6,7)8)23(19)30-15-21(26)27/h9-14,21H,15H2,1-8H3,(H,28,29)/b10-9+,16-12+,17-11- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141605
((E)-3-[7-(3,5-Diisopropyl-2-propoxy-phenyl)-benzof...)Show SMILES CCCOc1c(cc(cc1-c1cccc2cc(oc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C27H32O4/c1-7-11-30-27-22(17(4)5)13-20(16(2)3)14-23(27)21-10-8-9-19-15-24(31-26(19)21)18(6)12-25(28)29/h8-10,12-17H,7,11H2,1-6H3,(H,28,29)/b18-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Antagonist activity for Retinoic X receptor alpha in CV1 cells |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141602
((E)-3-{7-[2-(3-Fluoro-propoxy)-3,5-diisopropyl-phe...)Show SMILES CC(C)c1cc(C(C)C)c(OCCCF)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C27H31FO4/c1-16(2)20-13-22(17(3)4)27(31-11-7-10-28)23(14-20)21-9-6-8-19-15-24(32-26(19)21)18(5)12-25(29)30/h6,8-9,12-17H,7,10-11H2,1-5H3,(H,29,30)/b18-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141600
((Z)-3-{7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C(/F)C(O)=O Show InChI InChI=1S/C26H27F3O4/c1-13(2)17-9-19(14(3)4)25(32-12-22(27)28)20(10-17)18-8-6-7-16-11-21(33-24(16)18)15(5)23(29)26(30)31/h6-11,13-14,22H,12H2,1-5H3,(H,30,31)/b23-15- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141592
((E)-3-[4-(3,5-Di-tert-butyl-2-methyl-phenyl)-benzo...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1C)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C27H32O2S/c1-16(12-25(28)29)24-15-21-19(10-9-11-23(21)30-24)20-13-18(26(3,4)5)14-22(17(20)2)27(6,7)8/h9-15H,1-8H3,(H,28,29)/b16-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141596
((E)-3-{4-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy...)Show SMILES C\C(=C/C(O)=O)c1cc2c(cccc2s1)-c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C Show InChI InChI=1S/C28H32F2O3S/c1-16(11-25(31)32)23-14-19-18(9-8-10-22(19)34-23)20-12-17(27(2,3)4)13-21(28(5,6)7)26(20)33-15-24(29)30/h8-14,24H,15H2,1-7H3,(H,31,32)/b16-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141589
((Z)-3-[7-(2-Butoxy-3,5-diisopropyl-phenyl)-benzofu...)Show SMILES CCCCOc1c(cc(cc1-c1cccc2cc(oc12)C(\C)=C(/F)C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C28H33FO4/c1-7-8-12-32-27-22(17(4)5)13-20(16(2)3)14-23(27)21-11-9-10-19-15-24(33-26(19)21)18(6)25(29)28(30)31/h9-11,13-17H,7-8,12H2,1-6H3,(H,30,31)/b25-18- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141600
((Z)-3-{7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C(/F)C(O)=O Show InChI InChI=1S/C26H27F3O4/c1-13(2)17-9-19(14(3)4)25(32-12-22(27)28)20(10-17)18-8-6-7-16-11-21(33-24(16)18)15(5)23(29)26(30)31/h6-11,13-14,22H,12H2,1-5H3,(H,30,31)/b23-15- | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141594
((E)-3-{7-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethox...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C26H27F3O4/c1-14(2)18-10-20(15(3)4)25(32-13-26(27,28)29)21(11-18)19-8-6-7-17-12-22(33-24(17)19)16(5)9-23(30)31/h6-12,14-15H,13H2,1-5H3,(H,30,31)/b16-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 142 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141603
((E)-3-{7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C26H28F2O4/c1-14(2)18-10-20(15(3)4)26(31-13-23(27)28)21(11-18)19-8-6-7-17-12-22(32-25(17)19)16(5)9-24(29)30/h6-12,14-15,23H,13H2,1-5H3,(H,29,30)/b16-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 161 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141594
((E)-3-{7-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethox...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C26H27F3O4/c1-14(2)18-10-20(15(3)4)25(32-13-26(27,28)29)21(11-18)19-8-6-7-17-12-22(33-24(17)19)16(5)9-23(30)31/h6-12,14-15H,13H2,1-5H3,(H,30,31)/b16-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 198 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Antagonist activity for Retinoic X receptor alpha in CV1 cells |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-beta
(Homo sapiens (Human)) | BDBM50141603
((E)-3-{7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C26H28F2O4/c1-14(2)18-10-20(15(3)4)26(31-13-23(27)28)21(11-18)19-8-6-7-17-12-22(32-25(17)19)16(5)9-24(29)30/h6-12,14-15,23H,13H2,1-5H3,(H,29,30)/b16-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 261 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from Retinoic X receptor beta |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-alpha
(Homo sapiens (Human)) | BDBM50141593
((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...)Show SMILES CCOc1c(cc(cc1-c1cccc2cc(sc12)C(\C)=C\C(O)=O)C(C)C)C(C)C Show InChI InChI=1S/C26H30O3S/c1-7-29-25-21(16(4)5)12-19(15(2)3)13-22(25)20-10-8-9-18-14-23(30-26(18)20)17(6)11-24(27)28/h8-16H,7H2,1-6H3,(H,27,28)/b17-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 271 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141594
((E)-3-{7-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethox...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C26H27F3O4/c1-14(2)18-10-20(15(3)4)25(32-13-26(27,28)29)21(11-18)19-8-6-7-17-12-22(33-24(17)19)16(5)9-23(30)31/h6-12,14-15H,13H2,1-5H3,(H,30,31)/b16-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 334 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Homo sapiens (Human)) | BDBM50141603
((E)-3-{7-[2-(2,2-Difluoro-ethoxy)-3,5-diisopropyl-...)Show SMILES CC(C)c1cc(C(C)C)c(OCC(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O Show InChI InChI=1S/C26H28F2O4/c1-14(2)18-10-20(15(3)4)26(31-13-23(27)28)21(11-18)19-8-6-7-17-12-22(32-25(17)19)16(5)9-24(29)30/h6-12,14-15,23H,13H2,1-5H3,(H,29,30)/b16-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]-9-cis-RA from retinoic X receptor gamma |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |
Retinoic acid receptor RXR-gamma
(Mus musculus) | BDBM50129720
((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...)Show SMILES C\C(\C=C\C=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O Show InChI InChI=1S/C25H34F2O3/c1-16(12-22(28)29)10-9-11-17(2)19-13-18(24(3,4)5)14-20(25(6,7)8)23(19)30-15-21(26)27/h9-14,21H,15H2,1-8H3,(H,28,29)/b10-9+,16-12+,17-11- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Binding affinity against retinoic acid receptor gamma by [3H]-ATRA displacement. |
Bioorg Med Chem Lett 14: 1593-8 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF |
More data for this Ligand-Target Pair | |