Compile Data Set for Download or QSAR

Found 58 hits Enz. Inhib. hit(s) with all data for entry = 50000150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM50241660 (CHEMBL4084398) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241662 (CHEMBL4104741) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(C)(=O)=O)C1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C26H35FN4O2S/c1-28(2)25-18-30(24-12-9-20-5-4-6-23(27)26(20)24)17-22(25)19-7-10-21(11-8-19)29-13-15-31(16-14-29)34(3,32)33/h4-8,10-11,22,24-25H,9,12-18H2,1-3H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235631 (CHEMBL4060827) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)C1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM223986 ((3R,4S)-1-[(1S)-7-fluoroindan-1-yl]-N,N-dimethyl-4...) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1cn(C)c2ccccc12)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C24H28FN3/c1-26(2)23-15-28(22-12-11-16-7-6-9-20(25)24(16)22)14-19(23)18-13-27(3)21-10-5-4-8-17(18)21/h4-10,13,19,22-23H,11-12,14-15H2,1-3H3/t19-,22+,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50241655 (CHEMBL4071358) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241646 (CHEMBL4102320) Show SMILES COc1ccc(cc1OC)[C@H]1CN(C[C@@H]1N(C)C)C1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C23H29FN2O2/c1-25(2)20-14-26(19-10-8-15-6-5-7-18(24)23(15)19)13-17(20)16-9-11-21(27-3)22(12-16)28-4/h5-7,9,11-12,17,19-20H,8,10,13-14H2,1-4H3/t17-,19?,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235648 (CHEMBL4081496) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O |r| Show InChI InChI=1S/C26H35FN4O/c1-19-6-5-7-25(27)23(19)16-29-17-24(26(18-29)28(3)4)21-8-10-22(11-9-21)31-14-12-30(13-15-31)20(2)32/h5-11,24,26H,12-18H2,1-4H3/t24-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM223985 (rac-(3R,4S)-1-(2-fluoro-6-methylbenzyl)-N,N-dimeth...) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C23H28FN3/c1-16-8-7-10-21(24)18(16)13-27-14-20(23(15-27)25(2)3)19-12-26(4)22-11-6-5-9-17(19)22/h5-12,20,23H,13-15H2,1-4H3/t20-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241650 (CHEMBL4100850) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cc(O)cc2Br)C[C@@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C22H25BrFN3O/c1-25(2)22-13-27(12-18-19(23)8-14(28)9-20(18)24)11-17(22)16-10-26(3)21-7-5-4-6-15(16)21/h4-10,17,22,28H,11-13H2,1-3H3/t17-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241648 (CHEMBL4072980) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)S(C)(=O)=O |r| Show InChI InChI=1S/C21H27FN2O2S/c1-15-6-5-7-20(22)18(15)12-24-13-19(21(14-24)23(2)3)16-8-10-17(11-9-16)27(4,25)26/h5-11,19,21H,12-14H2,1-4H3/t19-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235626 (CHEMBL4075197) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C22H25BrFN3/c1-25(2)22-14-27(13-18-19(23)8-6-9-20(18)24)12-17(22)16-11-26(3)21-10-5-4-7-15(16)21/h4-11,17,22H,12-14H2,1-3H3/t17-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50241645 (CHEMBL4078052) Show SMILES COc1ccc(cc1OC)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1N(C)C |r| Show InChI InChI=1S/C22H29FN2O2/c1-15-7-6-8-19(23)17(15)12-25-13-18(20(14-25)24(2)3)16-9-10-21(26-4)22(11-16)27-5/h6-11,18,20H,12-14H2,1-5H3/t18-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241659 (CHEMBL4079004) Show SMILES COc1ccc(cc1OC)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1N(C)C |r| Show InChI InChI=1S/C21H26BrFN2O2/c1-24(2)19-13-25(12-16-17(22)6-5-7-18(16)23)11-15(19)14-8-9-20(26-3)21(10-14)27-4/h5-10,15,19H,11-13H2,1-4H3/t15-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241657 (CHEMBL4077899) Show SMILES CN(C)[C@@H]1CN(C[C@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25+,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241656 (CHEMBL4092154) Show SMILES CN(C)[C@@H]1CN(C[C@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241647 (CHEMBL4067115) Show SMILES CN(C)[C@@H]1CN(Cc2c(F)cccc2Br)C[C@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C22H25BrFN3/c1-25(2)22-14-27(13-18-19(23)8-6-9-20(18)24)12-17(22)16-11-26(3)21-10-5-4-7-15(16)21/h4-11,17,22H,12-14H2,1-3H3/t17-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241661 (CHEMBL4103307) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H22BrFN2O/c1-22(2)19-12-23(11-16-17(20)4-3-5-18(16)21)10-15(19)13-6-8-14(24)9-7-13/h3-9,15,19,24H,10-12H2,1-2H3/t15-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235656 (CHEMBL4085375) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1ccccc1 |r| Show InChI InChI=1S/C19H22BrFN2/c1-22(2)19-13-23(11-15(19)14-7-4-3-5-8-14)12-16-17(20)9-6-10-18(16)21/h3-10,15,19H,11-13H2,1-2H3/t15-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241653 (CHEMBL4093678) Show SMILES CN(C)[C@@H]1CN(Cc2c(C)cccc2F)C[C@H]1c1ccc(cc1)S(C)(=O)=O |r| Show InChI InChI=1S/C21H27FN2O2S/c1-15-6-5-7-20(22)18(15)12-24-13-19(21(14-24)23(2)3)16-8-10-17(11-9-16)27(4,25)26/h5-11,19,21H,12-14H2,1-4H3/t19-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241649 (CHEMBL4093134) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1ccccn1 |r| Show InChI InChI=1S/C18H21BrFN3/c1-22(2)18-12-23(10-13-15(19)6-5-7-16(13)20)11-14(18)17-8-3-4-9-21-17/h3-9,14,18H,10-12H2,1-2H3/t14-,18+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM223984 (rac-(3R,4S)-1-(2-methoxybenzyl)-N,N-dimethyl-4-(1-...) Show SMILES COc1ccccc1CN1C[C@@H]([C@H](C1)c1cn(C)c2ccccc12)N(C)C |r| Show InChI InChI=1S/C23H29N3O/c1-24(2)22-16-26(13-17-9-5-8-12-23(17)27-4)15-20(22)19-14-25(3)21-11-7-6-10-18(19)21/h5-12,14,20,22H,13,15-16H2,1-4H3/t20-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to GST tagged EED (unknown origin) after 1 hr by OG(488) probe based TR-FRET assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50241658 (CHEMBL4064198) Show SMILES CN(C)c1cc(ccn1)N1CCc2ccccc2C1 Show InChI InChI=1S/C16H19N3/c1-18(2)16-11-15(7-9-17-16)19-10-8-13-5-3-4-6-14(13)12-19/h3-7,9,11H,8,10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50127824 (2-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline | C...) Show SMILES C1Cc2ccccc2CN1c1ccncc1 Show InChI InChI=1S/C14H14N2/c1-2-4-13-11-16(10-7-12(13)3-1)14-5-8-15-9-6-14/h1-6,8-9H,7,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241652 (CHEMBL4074086) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C19H22N2O4S/c1-25-17-9-5-4-8-16(17)20-11-13-21(14-12-20)19(22)15-7-3-6-10-18(15)26(2,23)24/h3-10H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241659 (CHEMBL4079004) Show SMILES COc1ccc(cc1OC)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1N(C)C |r| Show InChI InChI=1S/C21H26BrFN2O2/c1-24(2)19-13-25(12-16-17(22)6-5-7-18(16)23)11-15(19)14-8-9-20(26-3)21(10-14)27-4/h5-10,15,19H,11-13H2,1-4H3/t15-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241653 (CHEMBL4093678) Show SMILES CN(C)[C@@H]1CN(Cc2c(C)cccc2F)C[C@H]1c1ccc(cc1)S(C)(=O)=O |r| Show InChI InChI=1S/C21H27FN2O2S/c1-15-6-5-7-20(22)18(15)12-24-13-19(21(14-24)23(2)3)16-8-10-17(11-9-16)27(4,25)26/h5-11,19,21H,12-14H2,1-4H3/t19-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241661 (CHEMBL4103307) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H22BrFN2O/c1-22(2)19-12-23(11-16-17(20)4-3-5-18(16)21)10-15(19)13-6-8-14(24)9-7-13/h3-9,15,19,24H,10-12H2,1-2H3/t15-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to biotin labelled human EED (78 to 441 residues) by SPR assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50127824 (2-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline | C...) Show SMILES C1Cc2ccccc2CN1c1ccncc1 Show InChI InChI=1S/C14H14N2/c1-2-4-13-11-16(10-7-12(13)3-1)14-5-8-15-9-6-14/h1-6,8-9H,7,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235626 (CHEMBL4075197) Show SMILES CN(C)[C@H]1CN(Cc2c(F)cccc2Br)C[C@@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C22H25BrFN3/c1-25(2)22-14-27(13-18-19(23)8-6-9-20(18)24)12-17(22)16-11-26(3)21-10-5-4-7-15(16)21/h4-11,17,22H,12-14H2,1-3H3/t17-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50241660 (CHEMBL4084398) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM223985 (rac-(3R,4S)-1-(2-fluoro-6-methylbenzyl)-N,N-dimeth...) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C23H28FN3/c1-16-8-7-10-21(24)18(16)13-27-14-20(23(15-27)25(2)3)19-12-26(4)22-11-6-5-9-17(19)22/h5-12,20,23H,13-15H2,1-4H3/t20-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241660 (CHEMBL4084398) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241662 (CHEMBL4104741) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(C)(=O)=O)C1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C26H35FN4O2S/c1-28(2)25-18-30(24-12-9-20-5-4-6-23(27)26(20)24)17-22(25)19-7-10-21(11-8-19)29-13-15-31(16-14-29)34(3,32)33/h4-8,10-11,22,24-25H,9,12-18H2,1-3H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235631 (CHEMBL4060827) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)C1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to biotin labelled human EED (78 to 441 residues) by SPR assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235648 (CHEMBL4081496) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O |r| Show InChI InChI=1S/C26H35FN4O/c1-19-6-5-7-25(27)23(19)16-29-17-24(26(18-29)28(3)4)21-8-10-22(11-9-21)31-14-12-30(13-15-31)20(2)32/h5-11,24,26H,12-18H2,1-4H3/t24-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM223984 (rac-(3R,4S)-1-(2-methoxybenzyl)-N,N-dimethyl-4-(1-...) Show SMILES COc1ccccc1CN1C[C@@H]([C@H](C1)c1cn(C)c2ccccc12)N(C)C |r| Show InChI InChI=1S/C23H29N3O/c1-24(2)22-16-26(13-17-9-5-8-12-23(17)27-4)15-20(22)19-14-25(3)21-11-7-6-10-18(19)21/h5-12,14,20,22H,13,15-16H2,1-4H3/t20-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50241657 (CHEMBL4077899) Show SMILES CN(C)[C@@H]1CN(C[C@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25+,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241656 (CHEMBL4092154) Show SMILES CN(C)[C@@H]1CN(C[C@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Binding affinity to biotin labelled human EED (78 to 441 residues) by SPR assay				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241655 (CHEMBL4071358) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241658 (CHEMBL4064198) Show SMILES CN(C)c1cc(ccn1)N1CCc2ccccc2C1 Show InChI InChI=1S/C16H19N3/c1-18(2)16-11-15(7-9-17-16)19-10-8-13-5-3-4-6-14(13)12-19/h3-7,9,11H,8,10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM223986 ((3R,4S)-1-[(1S)-7-fluoroindan-1-yl]-N,N-dimethyl-4...) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1cn(C)c2ccccc12)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C24H28FN3/c1-26(2)23-15-28(22-12-11-16-7-6-9-20(25)24(16)22)14-19(23)18-13-27(3)21-10-5-4-8-17(18)21/h4-10,13,19,22-23H,11-12,14-15H2,1-3H3/t19-,22+,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polycomb protein EED (Homo sapiens (Human))	BDBM50241657 (CHEMBL4077899) Show SMILES CN(C)[C@@H]1CN(C[C@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25+,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of Fibrinogen binding to Fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241656 (CHEMBL4092154) Show SMILES CN(C)[C@@H]1CN(C[C@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25-,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241655 (CHEMBL4071358) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)[C@@H]1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50127824 (2-Pyridin-4-yl-1,2,3,4-tetrahydro-isoquinoline | C...) Show SMILES C1Cc2ccccc2CN1c1ccncc1 Show InChI InChI=1S/C14H14N2/c1-2-4-13-11-16(10-7-12(13)3-1)14-5-8-15-9-6-14/h1-6,8-9H,7,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241648 (CHEMBL4072980) Show SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)S(C)(=O)=O |r| Show InChI InChI=1S/C21H27FN2O2S/c1-15-6-5-7-20(22)18(15)12-24-13-19(21(14-24)23(2)3)16-8-10-17(11-9-16)27(4,25)26/h5-11,19,21H,12-14H2,1-4H3/t19-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241653 (CHEMBL4093678) Show SMILES CN(C)[C@@H]1CN(Cc2c(C)cccc2F)C[C@H]1c1ccc(cc1)S(C)(=O)=O |r| Show InChI InChI=1S/C21H27FN2O2S/c1-15-6-5-7-20(22)18(15)12-24-13-19(21(14-24)23(2)3)16-8-10-17(11-9-16)27(4,25)26/h5-11,19,21H,12-14H2,1-4H3/t19-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241647 (CHEMBL4067115) Show SMILES CN(C)[C@@H]1CN(Cc2c(F)cccc2Br)C[C@H]1c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C22H25BrFN3/c1-25(2)22-14-27(13-18-19(23)8-6-9-20(18)24)12-17(22)16-11-26(3)21-10-5-4-7-15(16)21/h4-11,17,22H,12-14H2,1-3H3/t17-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of Fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50235631 (CHEMBL4060827) Show SMILES CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)C(C)=O)C1CCc2cccc(F)c12 |r| Show InChI InChI=1S/C27H35FN4O/c1-19(33)30-13-15-31(16-14-30)22-10-7-20(8-11-22)23-17-32(18-26(23)29(2)3)25-12-9-21-5-4-6-24(28)27(21)25/h4-8,10-11,23,25-26H,9,12-18H2,1-3H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50241652 (CHEMBL4074086) Show SMILES COc1ccccc1N1CCN(CC1)C(=O)c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C19H22N2O4S/c1-25-17-9-5-4-8-16(17)20-11-13-21(14-12-20)19(22)15-7-3-6-10-18(15)26(2,23)24/h3-10H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8321-8335 (2017) Article DOI: 10.1021/acs.jmedchem.7b00576 BindingDB Entry DOI: 10.7270/Q2TM7D8G
					More data for this Ligand-Target Pair

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