Compile Data Set for Download or QSAR

Found 53 hits Enz. Inhib. hit(s) with all data for entry = 50000287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DCN1-like protein 1 (Homo sapiens)	BDBM50245154 (CHEMBL4067795 | US11116757, No. A10) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C28H35N3O/c1-3-9-22(2)30-18-16-27(17-19-30)31(21-23-10-5-4-6-11-23)28(32)29-26-15-14-24-12-7-8-13-25(24)20-26/h4-8,10-15,20,22,27H,3,9,16-19,21H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Binding affinity for Adenosine A1 receptor using N-[3H] cyclohexyladenosine in rat forebrain membranes				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245237 (CHEMBL4074213 | US11116757, No. A7) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H29Cl2N3O/c1-2-3-13-27-14-11-20(12-15-27)28(17-18-7-5-4-6-8-18)23(29)26-19-9-10-21(24)22(25)16-19/h4-10,16,20H,2-3,11-15,17H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
DCN1-like protein 1 (Homo sapiens)	BDBM50245225 (CHEMBL4099097 | US11116757, No. A15) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C25H32F3N3O/c1-3-8-19(2)30-15-13-23(14-16-30)31(18-20-9-5-4-6-10-20)24(32)29-22-12-7-11-21(17-22)25(26,27)28/h4-7,9-12,17,19,23H,3,8,13-16,18H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245227 (CHEMBL4077431 | US11116757, No. A4) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(I)cc1 Show InChI InChI=1S/C24H32IN3O/c1-3-7-19(2)27-16-14-23(15-17-27)28(18-20-8-5-4-6-9-20)24(29)26-22-12-10-21(25)11-13-22/h4-6,8-13,19,23H,3,7,14-18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245148 (CHEMBL4077759 | US11116757, No. A6) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C25H31F4N3O/c1-3-7-18(2)31-12-10-23(11-13-31)32(17-19-8-5-4-6-9-19)24(33)30-22-15-20(25(27,28)29)14-21(26)16-22/h4-6,8-9,14-16,18,23H,3,7,10-13,17H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245131 (CHEMBL4094517 | US11116757, No. A5) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C24H32BrN3O/c1-3-7-19(2)27-16-14-23(15-17-27)28(18-20-8-5-4-6-9-20)24(29)26-22-12-10-21(25)11-13-22/h4-6,8-13,19,23H,3,7,14-18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245153 (CHEMBL4078685 | US11116757, No. A8) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc2CCCc2c1 Show InChI InChI=1S/C27H37N3O/c1-3-8-21(2)29-17-15-26(16-18-29)30(20-22-9-5-4-6-10-22)27(31)28-25-14-13-23-11-7-12-24(23)19-25/h4-6,9-10,13-14,19,21,26H,3,7-8,11-12,15-18,20H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245140 (CHEMBL4103209 | US11116757, No. A11) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(Cl)c(c1)[N+]([O-])=O Show InChI InChI=1S/C24H31ClN4O3/c1-3-7-18(2)27-14-12-21(13-15-27)28(17-19-8-5-4-6-9-19)24(30)26-20-10-11-22(25)23(16-20)29(31)32/h4-6,8-11,16,18,21H,3,7,12-15,17H2,1-2H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245130 (CHEMBL4086099 | US11116757, No. A13) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C24H32ClN3O/c1-3-7-19(2)27-16-14-23(15-17-27)28(18-20-8-5-4-6-9-20)24(29)26-22-12-10-21(25)11-13-22/h4-6,8-13,19,23H,3,7,14-18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245228 (CHEMBL4065355 | US11116757, No. A42) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(C)c(F)c1 Show InChI InChI=1S/C25H34FN3O/c1-4-8-20(3)28-15-13-23(14-16-28)29(18-21-9-6-5-7-10-21)25(30)27-22-12-11-19(2)24(26)17-22/h5-7,9-12,17,20,23H,4,8,13-16,18H2,1-3H3,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245156 (CHEMBL4079749 | US11116757, No. A45) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C24H29F4N3O/c1-2-3-11-30-12-9-22(10-13-30)31(17-18-7-5-4-6-8-18)23(32)29-21-15-19(24(26,27)28)14-20(25)16-21/h4-8,14-16,22H,2-3,9-13,17H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	256	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245142 (CHEMBL4105639 | US11116757, No. A47) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C26H31F3N4O/c1-3-7-19(2)32-14-12-23(13-15-32)33(18-20-8-5-4-6-9-20)25(34)31-22-11-10-21(17-30)24(16-22)26(27,28)29/h4-6,8-11,16,19,23H,3,7,12-15,18H2,1-2H3,(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245143 (CHEMBL4087755 | US11116757, No. A57) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C25H31F4N3O/c1-3-7-18(2)31-14-12-21(13-15-31)32(17-19-8-5-4-6-9-19)24(33)30-20-10-11-23(26)22(16-20)25(27,28)29/h4-6,8-11,16,18,21H,3,7,12-15,17H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245117 (CHEMBL4077301 | US11116757, No. A35) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C24H32ClN3O/c1-3-8-19(2)27-15-13-23(14-16-27)28(18-20-9-5-4-6-10-20)24(29)26-22-12-7-11-21(25)17-22/h4-7,9-12,17,19,23H,3,8,13-16,18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245118 (CHEMBL4064579 | US11116757, No. A41) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C25H32F3N3O/c1-3-7-19(2)30-16-14-23(15-17-30)31(18-20-8-5-4-6-9-20)24(32)29-22-12-10-21(11-13-22)25(26,27)28/h4-6,8-13,19,23H,3,7,14-18H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245238 (CHEMBL4103413 | US11116757, No. A28) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(C)c(Cl)c1 Show InChI InChI=1S/C24H32ClN3O/c1-3-4-14-27-15-12-22(13-16-27)28(18-20-8-6-5-7-9-20)24(29)26-21-11-10-19(2)23(25)17-21/h5-11,17,22H,3-4,12-16,18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245226 (CHEMBL4093853 | US11116757, No. A33) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1)C(C)C Show InChI InChI=1S/C27H39N3O/c1-5-10-22(4)29-17-15-26(16-18-29)30(20-23-11-7-6-8-12-23)27(31)28-25-14-9-13-24(19-25)21(2)3/h6-9,11-14,19,21-22,26H,5,10,15-18,20H2,1-4H3,(H,28,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245132 (CHEMBL4102261 | US11116757, No. A50) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(C)cc1 Show InChI InChI=1S/C25H35N3O/c1-4-8-21(3)27-17-15-24(16-18-27)28(19-22-9-6-5-7-10-22)25(29)26-23-13-11-20(2)12-14-23/h5-7,9-14,21,24H,4,8,15-19H2,1-3H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245210 (CHEMBL4093655 | US11116757, No. A60) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C23H30ClN3O/c1-2-3-14-26-15-12-22(13-16-26)27(18-19-8-5-4-6-9-19)23(28)25-21-11-7-10-20(24)17-21/h4-11,17,22H,2-3,12-16,18H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	358	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245229 (CHEMBL4102027 | US11116757, No. A67) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(Cl)c1 Show InChI InChI=1S/C24H31ClFN3O/c1-3-7-18(2)28-12-10-23(11-13-28)29(17-19-8-5-4-6-9-19)24(30)27-22-15-20(25)14-21(26)16-22/h4-6,8-9,14-16,18,23H,3,7,10-13,17H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245214 (CHEMBL4065590 | US11116757, No. A70) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1F)C(F)(F)F Show InChI InChI=1S/C24H29F4N3O/c1-2-3-14-30-15-12-19(13-16-30)31(17-18-8-5-4-6-9-18)23(32)29-21-11-7-10-20(22(21)25)24(26,27)28/h4-11,19H,2-3,12-17H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245223 (CHEMBL4085483 | US11116757, No. A26) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C24H29F4N3O/c1-2-3-13-30-14-11-20(12-15-30)31(17-18-7-5-4-6-8-18)23(32)29-19-9-10-22(25)21(16-19)24(26,27)28/h4-10,16,20H,2-3,11-15,17H2,1H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	612	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245152 (CHEMBL4096706 | US11116757, No. A73) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc2ncsc2c1 Show InChI InChI=1S/C25H32N4OS/c1-3-7-19(2)28-14-12-22(13-15-28)29(17-20-8-5-4-6-9-20)25(30)27-21-10-11-23-24(16-21)31-18-26-23/h4-6,8-11,16,18-19,22H,3,7,12-15,17H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	626	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245133 (CHEMBL4084296 | US11116757, No. A74) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(cc1)C(C)C Show InChI InChI=1S/C27H39N3O/c1-5-9-22(4)29-18-16-26(17-19-29)30(20-23-10-7-6-8-11-23)27(31)28-25-14-12-24(13-15-25)21(2)3/h6-8,10-15,21-22,26H,5,9,16-20H2,1-4H3,(H,28,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	654	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245141 (CHEMBL4086785 | US11116757, No. A80) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C24H31F2N3O/c1-3-7-18(2)28-14-12-21(13-15-28)29(17-19-8-5-4-6-9-19)24(30)27-20-10-11-22(25)23(26)16-20/h4-6,8-11,16,18,21H,3,7,12-15,17H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	817	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245231 (CHEMBL4089008 | US11116757, No. A86) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc2OCOc2c1 Show InChI InChI=1S/C25H33N3O3/c1-3-7-19(2)27-14-12-22(13-15-27)28(17-20-8-5-4-6-9-20)25(29)26-21-10-11-23-24(16-21)31-18-30-23/h4-6,8-11,16,19,22H,3,7,12-15,17-18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245224 (CHEMBL4075257 | US11116757, No. A89) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C23H29ClFN3O/c1-2-3-13-27-14-11-20(12-15-27)28(17-18-7-5-4-6-8-18)23(29)26-19-9-10-22(25)21(24)16-19/h4-10,16,20H,2-3,11-15,17H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245115 (CHEMBL4062267 | US11116757, No. A95) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C24H33N3O/c1-3-4-15-26-16-13-23(14-17-26)27(19-21-10-6-5-7-11-21)24(28)25-22-12-8-9-20(2)18-22/h5-12,18,23H,3-4,13-17,19H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245116 (CHEMBL4101581 | US11116757, No. A72) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C24H32FN3O/c1-3-8-19(2)27-15-13-23(14-16-27)28(18-20-9-5-4-6-10-20)24(29)26-22-12-7-11-21(25)17-22/h4-7,9-12,17,19,23H,3,8,13-16,18H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245139 (CHEMBL4078934 | US11116757, No. A100) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C28H41N3O/c1-6-10-22(2)30-19-17-26(18-20-30)31(21-23-11-8-7-9-12-23)27(32)29-25-15-13-24(14-16-25)28(3,4)5/h7-9,11-16,22,26H,6,10,17-21H2,1-5H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245232 (CHEMBL4066268 | US11116757, No. A126) Show SMILES CSC(C)CCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C25H31F4N3OS/c1-18(34-2)8-11-31-12-9-23(10-13-31)32(17-19-6-4-3-5-7-19)24(33)30-22-15-20(25(27,28)29)14-21(26)16-22/h3-7,14-16,18,23H,8-13,17H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245211 (CHEMBL4090274 | US11116757, No. A104) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C23H30N4O3/c1-2-3-14-25-15-12-21(13-16-25)26(18-19-8-5-4-6-9-19)23(28)24-20-10-7-11-22(17-20)27(29)30/h4-11,17,21H,2-3,12-16,18H2,1H3,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245173 (CHEMBL4087623 | US11116757, No. A133) Show SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(CCCc3ccccc3)CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C29H31F4N3O/c30-25-18-24(29(31,32)33)19-26(20-25)34-28(37)36(21-23-10-5-2-6-11-23)27-13-16-35(17-14-27)15-7-12-22-8-3-1-4-9-22/h1-6,8-11,18-20,27H,7,12-17,21H2,(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245236 (CHEMBL4066082 | US11116757, No. A136) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C23H30FN3O/c1-2-3-14-26-15-12-22(13-16-26)27(18-19-8-5-4-6-9-19)23(28)25-21-11-7-10-20(24)17-21/h4-11,17,22H,2-3,12-16,18H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245212 (CHEMBL4100965 | US11116757, No. A242) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cccc(c1)C#N Show InChI InChI=1S/C24H30N4O/c1-2-3-14-27-15-12-23(13-16-27)28(19-20-8-5-4-6-9-20)24(29)26-22-11-7-10-21(17-22)18-25/h4-11,17,23H,2-3,12-16,19H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245213 (CHEMBL4069860 | US11116757, No. A142) Show SMILES CCCCN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(F)c1 Show InChI InChI=1S/C23H29F2N3O/c1-2-3-11-27-12-9-22(10-13-27)28(17-18-7-5-4-6-8-18)23(29)26-21-15-19(24)14-20(25)16-21/h4-8,14-16,22H,2-3,9-13,17H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245207 (CHEMBL4084962 | US11116757, No. A143) Show SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(C\C=C\c3ccccc3)CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C29H29F4N3O/c30-25-18-24(29(31,32)33)19-26(20-25)34-28(37)36(21-23-10-5-2-6-11-23)27-13-16-35(17-14-27)15-7-12-22-8-3-1-4-9-22/h1-12,18-20,27H,13-17,21H2,(H,34,37)/b12-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of [3H](+)-PN200-110 binding to L-type calcium channel 1,4-DHP binding site of rat ventricular myocytes				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245176 (CHEMBL4103074 | US11116757, No. A144) Show SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(CC3CCOC3)CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C25H29F4N3O2/c26-21-12-20(25(27,28)29)13-22(14-21)30-24(33)32(16-18-4-2-1-3-5-18)23-6-9-31(10-7-23)15-19-8-11-34-17-19/h1-5,12-14,19,23H,6-11,15-17H2,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of [3H](+)-PN200-110 binding to L-type calcium channel 1,4-DHP binding site of rat ventricular myocytes				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245149 (CHEMBL4066771 | US11116757, No. A154) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(ccc1F)C(F)(F)F Show InChI InChI=1S/C25H31F4N3O/c1-3-7-18(2)31-14-12-21(13-15-31)32(17-19-8-5-4-6-9-19)24(33)30-23-16-20(25(27,28)29)10-11-22(23)26/h4-6,8-11,16,18,21H,3,7,12-15,17H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245151 (CHEMBL4104429 | US11116757, No. A165) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(Br)cc1C Show InChI InChI=1S/C25H34BrN3O/c1-4-8-20(3)28-15-13-23(14-16-28)29(18-21-9-6-5-7-10-21)25(30)27-24-12-11-22(26)17-19(24)2/h5-7,9-12,17,20,23H,4,8,13-16,18H2,1-3H3,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245230 (CHEMBL4086530 | US11116757, No. A178) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(nc1C)C(F)(F)F Show InChI InChI=1S/C25H33F3N4O/c1-4-8-18(2)31-15-13-21(14-16-31)32(17-20-9-6-5-7-10-20)24(33)30-22-11-12-23(25(26,27)28)29-19(22)3/h5-7,9-12,18,21H,4,8,13-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245155 (CHEMBL4104015 | US11116757, No. A207) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc2ncccc2c1 Show InChI InChI=1S/C27H34N4O/c1-3-8-21(2)30-17-14-25(15-18-30)31(20-22-9-5-4-6-10-22)27(32)29-24-12-13-26-23(19-24)11-7-16-28-26/h4-7,9-13,16,19,21,25H,3,8,14-15,17-18,20H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245209 (CHEMBL4085911 | US11116757, No. A205) Show SMILES Cn1ccc2cc(CN3CCC(CC3)N(Cc3ccccc3)C(=O)Nc3cc(F)cc(c3)C(F)(F)F)ccc12 Show InChI InChI=1S/C30H30F4N4O/c1-36-12-9-23-15-22(7-8-28(23)36)19-37-13-10-27(11-14-37)38(20-21-5-3-2-4-6-21)29(39)35-26-17-24(30(32,33)34)16-25(31)18-26/h2-9,12,15-18,27H,10-11,13-14,19-20H2,1H3,(H,35,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245208 (CHEMBL4103836 | US11116757, No. A211) Show SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(Cc3ccc(Cc4ccccc4)cc3)CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C34H33F4N3O/c35-30-20-29(34(36,37)38)21-31(22-30)39-33(42)41(24-27-9-5-2-6-10-27)32-15-17-40(18-16-32)23-28-13-11-26(12-14-28)19-25-7-3-1-4-8-25/h1-14,20-22,32H,15-19,23-24H2,(H,39,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245175 (CHEMBL4095324 | US11116757, No. A219) Show SMILES Cc1ccc(CN2CCC(CC2)N(Cc2ccccc2)C(=O)Nc2cc(F)cc(c2)C(F)(F)F)o1 Show InChI InChI=1S/C26H27F4N3O2/c1-18-7-8-24(35-18)17-32-11-9-23(10-12-32)33(16-19-5-3-2-4-6-19)25(34)31-22-14-20(26(28,29)30)13-21(27)15-22/h2-8,13-15,23H,9-12,16-17H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of [3H](+)-PN200-110 binding to L-type calcium channel 1,4-DHP binding site of rat ventricular myocytes				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245174 (CHEMBL4074885 | US11116757, No. A221) Show SMILES Cn1cncc1CN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C25H27F4N5O/c1-32-17-30-14-23(32)16-33-9-7-22(8-10-33)34(15-18-5-3-2-4-6-18)24(35)31-21-12-19(25(27,28)29)11-20(26)13-21/h2-6,11-14,17,22H,7-10,15-16H2,1H3,(H,31,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245235 (CHEMBL4063310 | US11116757, No. A217) Show SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(Cc3cccc(Oc4ccccc4)c3)CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C33H31F4N3O2/c34-27-19-26(33(35,36)37)20-28(21-27)38-32(41)40(23-24-8-3-1-4-9-24)29-14-16-39(17-15-29)22-25-10-7-13-31(18-25)42-30-11-5-2-6-12-30/h1-13,18-21,29H,14-17,22-23H2,(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245234 (CHEMBL4065214 | US11116757, No. A224) Show SMILES COc1ccccc1CN1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H29F4N3O2/c1-37-26-10-6-5-9-21(26)19-34-13-11-25(12-14-34)35(18-20-7-3-2-4-8-20)27(36)33-24-16-22(28(30,31)32)15-23(29)17-24/h2-10,15-17,25H,11-14,18-19H2,1H3,(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245206 (CHEMBL4079682 | US11116757, No. A222) Show SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(Cc3nc4ccccc4s3)CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H26F4N4OS/c29-21-14-20(28(30,31)32)15-22(16-21)33-27(37)36(17-19-6-2-1-3-7-19)23-10-12-35(13-11-23)18-26-34-24-8-4-5-9-25(24)38-26/h1-9,14-16,23H,10-13,17-18H2,(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of [3H](+)-PN200-110 binding to L-type calcium channel 1,4-DHP binding site of rat ventricular myocytes				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245179 (CHEMBL4074690 | US11116757, No. A228) Show SMILES Fc1cc(NC(=O)N(Cc2ccccc2)C2CCN(Cc3ccncc3)CC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C26H26F4N4O/c27-22-14-21(26(28,29)30)15-23(16-22)32-25(35)34(18-19-4-2-1-3-5-19)24-8-12-33(13-9-24)17-20-6-10-31-11-7-20/h1-7,10-11,14-16,24H,8-9,12-13,17-18H2,(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of [3H](+)-PN200-110 binding to L-type calcium channel 1,4-DHP binding site of rat ventricular myocytes				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair

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