Found 38 hits Enz. Inhib. hit(s) with all data for entry = 50038377 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50207446
(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)Show InChI InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375607
(CHEMBL259218)Show InChI InChI=1S/C15H13Cl2NO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375607
(CHEMBL259218)Show InChI InChI=1S/C15H13Cl2NO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 preincubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375607
(CHEMBL259218)Show InChI InChI=1S/C15H13Cl2NO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375606
(CHEMBL76084)Show InChI InChI=1S/C15H14ClNO2/c1-10-5-4-7-12(16)15(10)17-13-8-3-2-6-11(13)9-14(18)19/h2-8,17H,9H2,1H3,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375600
(CHEMBL407109)Show InChI InChI=1S/C15H12Cl3NO2/c1-8-2-3-13(9(4-8)5-14(20)21)19-15-11(17)6-10(16)7-12(15)18/h2-4,6-7,19H,5H2,1H3,(H,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375600
(CHEMBL407109)Show InChI InChI=1S/C15H12Cl3NO2/c1-8-2-3-13(9(4-8)5-14(20)21)19-15-11(17)6-10(16)7-12(15)18/h2-4,6-7,19H,5H2,1H3,(H,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375606
(CHEMBL76084)Show InChI InChI=1S/C15H14ClNO2/c1-10-5-4-7-12(16)15(10)17-13-8-3-2-6-11(13)9-14(18)19/h2-8,17H,9H2,1H3,(H,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375606
(CHEMBL76084)Show InChI InChI=1S/C15H14ClNO2/c1-10-5-4-7-12(16)15(10)17-13-8-3-2-6-11(13)9-14(18)19/h2-8,17H,9H2,1H3,(H,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375607
(CHEMBL259218)Show InChI InChI=1S/C15H13Cl2NO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375607
(CHEMBL259218)Show InChI InChI=1S/C15H13Cl2NO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375601
(CHEMBL76154)Show InChI InChI=1S/C16H17NO2/c1-11-6-5-7-12(2)16(11)17-14-9-4-3-8-13(14)10-15(18)19/h3-9,17H,10H2,1-2H3,(H,18,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375601
(CHEMBL76154)Show InChI InChI=1S/C16H17NO2/c1-11-6-5-7-12(2)16(11)17-14-9-4-3-8-13(14)10-15(18)19/h3-9,17H,10H2,1-2H3,(H,18,19) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375606
(CHEMBL76084)Show InChI InChI=1S/C15H14ClNO2/c1-10-5-4-7-12(16)15(10)17-13-8-3-2-6-11(13)9-14(18)19/h2-8,17H,9H2,1H3,(H,18,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375603
(CHEMBL407368)Show InChI InChI=1S/C16H16ClNO2/c1-10-6-7-14(12(8-10)9-15(19)20)18-16-11(2)4-3-5-13(16)17/h3-8,18H,9H2,1-2H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375607
(CHEMBL259218)Show InChI InChI=1S/C15H13Cl2NO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375607
(CHEMBL259218)Show InChI InChI=1S/C15H13Cl2NO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM13066
(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)Show InChI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375600
(CHEMBL407109)Show InChI InChI=1S/C15H12Cl3NO2/c1-8-2-3-13(9(4-8)5-14(20)21)19-15-11(17)6-10(16)7-12(15)18/h2-4,6-7,19H,5H2,1H3,(H,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375603
(CHEMBL407368)Show InChI InChI=1S/C16H16ClNO2/c1-10-6-7-14(12(8-10)9-15(19)20)18-16-11(2)4-3-5-13(16)17/h3-8,18H,9H2,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375603
(CHEMBL407368)Show InChI InChI=1S/C16H16ClNO2/c1-10-6-7-14(12(8-10)9-15(19)20)18-16-11(2)4-3-5-13(16)17/h3-8,18H,9H2,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50207446
(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)Show InChI InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50207446
(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)Show InChI InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 mediated PGE2 production in IL-1-beta-induced human dermal fibroblast cells |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50207446
(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)Show InChI InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 mediated PGE2 production in human whole blood |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375605
(CHEMBL258738)Show InChI InChI=1S/C15H11ClF3NO2/c16-11-6-3-5-10(15(17,18)19)14(11)20-12-7-2-1-4-9(12)8-13(21)22/h1-7,20H,8H2,(H,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 166 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375604
(CHEMBL259842)Show InChI InChI=1S/C17H19NO2/c1-3-13-9-6-7-12(2)17(13)18-15-10-5-4-8-14(15)11-16(19)20/h4-10,18H,3,11H2,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375604
(CHEMBL259842)Show InChI InChI=1S/C17H19NO2/c1-3-13-9-6-7-12(2)17(13)18-15-10-5-4-8-14(15)11-16(19)20/h4-10,18H,3,11H2,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375601
(CHEMBL76154)Show InChI InChI=1S/C16H17NO2/c1-11-6-5-7-12(2)16(11)17-14-9-4-3-8-13(14)10-15(18)19/h3-9,17H,10H2,1-2H3,(H,18,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 234 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375605
(CHEMBL258738)Show InChI InChI=1S/C15H11ClF3NO2/c16-11-6-3-5-10(15(17,18)19)14(11)20-12-7-2-1-4-9(12)8-13(21)22/h1-7,20H,8H2,(H,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 241 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375604
(CHEMBL259842)Show InChI InChI=1S/C17H19NO2/c1-3-13-9-6-7-12(2)17(13)18-15-10-5-4-8-14(15)11-16(19)20/h4-10,18H,3,11H2,1-2H3,(H,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 327 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50375602
(CHEMBL408156)Show InChI InChI=1S/C15H11F4NO2/c16-11-6-3-5-10(15(17,18)19)14(11)20-12-7-2-1-4-9(12)8-13(21)22/h1-7,20H,8H2,(H,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 629 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375605
(CHEMBL258738)Show InChI InChI=1S/C15H11ClF3NO2/c16-11-6-3-5-10(15(17,18)19)14(11)20-12-7-2-1-4-9(12)8-13(21)22/h1-7,20H,8H2,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 696 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Mus musculus (Mouse)) | BDBM50375602
(CHEMBL408156)Show InChI InChI=1S/C15H11F4NO2/c16-11-6-3-5-10(15(17,18)19)14(11)20-12-7-2-1-4-9(12)8-13(21)22/h1-7,20H,8H2,(H,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM50375604
(CHEMBL259842)Show InChI InChI=1S/C17H19NO2/c1-3-13-9-6-7-12(2)17(13)18-15-10-5-4-8-14(15)11-16(19)20/h4-10,18H,3,11H2,1-2H3,(H,19,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acid |
J Biol Chem 282: 16379-90 (2007)
Article DOI: 10.1074/jbc.M609883200 BindingDB Entry DOI: 10.7270/Q2X92C5N |
More data for this Ligand-Target Pair | |