Compile Data Set for Download or QSAR

Found 31 hits Enz. Inhib. hit(s) with all data for entry = 50038908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES OC1(N2CCN=C2c2ccccc12)c1ccc(Cl)cc1 |c:5| Show InChI InChI=1S/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50370475 (S,S-REBOXETINE) Show SMILES CCOc1ccccc1O[C@H]([C@H]1CNCCO1)c1ccccc1 |r| Show InChI InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 |r| Show InChI InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50124566 ((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...) Show SMILES CCOc1ccccc1OC(C1CNCCO1)c1ccccc1 Show InChI InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C18H22N2/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20/h2-5,7-10,19H,6,11-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297352 (4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3...) Show SMILES CNC[C@@H](O)[C@H](c1cccc(F)c1)n1c2c(F)cccc2n(C(C)C)c1=O |r| Show InChI InChI=1S/C20H23F2N3O2/c1-12(2)24-16-9-5-8-15(22)19(16)25(20(24)27)18(17(26)11-23-3)13-6-4-7-14(21)10-13/h4-10,12,17-18,23,26H,11H2,1-3H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297351 (1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...) Show SMILES CCn1c2cccc(F)c2n([C@H]([C@H](O)CNC)c2cccc(F)c2)c1=O |r| Show InChI InChI=1S/C19H21F2N3O2/c1-3-23-15-9-5-8-14(21)18(15)24(19(23)26)17(16(25)11-22-2)12-6-4-7-13(20)10-12/h4-10,16-17,22,25H,3,11H2,1-2H3/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297350 (1-Ethyl-3-[1-(3-fluoro-phenyl)-2-hydroxy-3-methyla...) Show SMILES CCn1c2ccccc2n([C@H]([C@H](O)CNC)c2cccc(F)c2)c1=O |r| Show InChI InChI=1S/C19H22FN3O2/c1-3-22-15-9-4-5-10-16(15)23(19(22)25)18(17(24)12-21-2)13-7-6-8-14(20)11-13/h4-11,17-18,21,24H,3,12H2,1-2H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297352 (4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3...) Show SMILES CNC[C@@H](O)[C@H](c1cccc(F)c1)n1c2c(F)cccc2n(C(C)C)c1=O |r| Show InChI InChI=1S/C20H23F2N3O2/c1-12(2)24-16-9-5-8-15(22)19(16)25(20(24)27)18(17(26)11-23-3)13-6-4-7-14(21)10-13/h4-10,12,17-18,23,26H,11H2,1-3H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297350 (1-Ethyl-3-[1-(3-fluoro-phenyl)-2-hydroxy-3-methyla...) Show SMILES CCn1c2ccccc2n([C@H]([C@H](O)CNC)c2cccc(F)c2)c1=O |r| Show InChI InChI=1S/C19H22FN3O2/c1-3-22-15-9-4-5-10-16(15)23(19(22)25)18(17(24)12-21-2)13-7-6-8-14(20)11-13/h4-11,17-18,21,24H,3,12H2,1-2H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297355 (4-Fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-ph...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2c(F)cccc2n(C(C)C)c1=O |r| Show InChI InChI=1S/C20H24FN3O2/c1-13(2)23-16-11-7-10-15(21)19(16)24(20(23)26)18(17(25)12-22-3)14-8-5-4-6-9-14/h4-11,13,17-18,22,25H,12H2,1-3H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM30130 (CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...) Show SMILES CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]hydroxytryptamine creatinine sulfate uptake at human SERT expressed in human JAR cells				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297351 (1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...) Show SMILES CCn1c2cccc(F)c2n([C@H]([C@H](O)CNC)c2cccc(F)c2)c1=O |r| Show InChI InChI=1S/C19H21F2N3O2/c1-3-23-15-9-5-8-14(21)18(15)24(19(23)26)17(16(25)11-22-2)12-6-4-7-13(20)10-12/h4-10,16-17,22,25H,3,11H2,1-2H3/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297361 (1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropy...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(C(C)C)c1=O |r| Show InChI InChI=1S/C20H25N3O2/c1-14(2)22-16-11-7-8-12-17(16)23(20(22)25)19(18(24)13-21-3)15-9-5-4-6-10-15/h4-12,14,18-19,21,24H,13H2,1-3H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10.8	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297349 (1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...) Show SMILES CCn1c2cccc(F)c2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O |r| Show InChI InChI=1S/C19H22FN3O2/c1-3-22-15-11-7-10-14(20)18(15)23(19(22)25)17(16(24)12-21-2)13-8-5-4-6-9-13/h4-11,16-17,21,24H,3,12H2,1-2H3/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297361 (1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropy...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(C(C)C)c1=O |r| Show InChI InChI=1S/C20H25N3O2/c1-14(2)22-16-11-7-8-12-17(16)23(20(22)25)19(18(24)13-21-3)15-9-5-4-6-10-15/h4-12,14,18-19,21,24H,13H2,1-3H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13.4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297349 (1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...) Show SMILES CCn1c2cccc(F)c2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O |r| Show InChI InChI=1S/C19H22FN3O2/c1-3-22-15-11-7-10-14(20)18(15)23(19(22)25)17(16(24)12-21-2)13-8-5-4-6-9-13/h4-11,16-17,21,24H,3,12H2,1-2H3/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13.8	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297363 (1-Ethyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phe...) Show SMILES CCn1c2ccccc2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O |r| Show InChI InChI=1S/C19H23N3O2/c1-3-21-15-11-7-8-12-16(15)22(19(21)24)18(17(23)13-20-2)14-9-5-4-6-10-14/h4-12,17-18,20,23H,3,13H2,1-2H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16.8	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297363 (1-Ethyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phe...) Show SMILES CCn1c2ccccc2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O |r| Show InChI InChI=1S/C19H23N3O2/c1-3-21-15-11-7-8-12-16(15)22(19(21)24)18(17(23)13-20-2)14-9-5-4-6-10-14/h4-12,17-18,20,23H,3,13H2,1-2H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297362 (1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropy...) Show SMILES CCCn1c2ccccc2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O |r| Show InChI InChI=1S/C20H25N3O2/c1-3-13-22-16-11-7-8-12-17(16)23(20(22)25)19(18(24)14-21-2)15-9-5-4-6-10-15/h4-12,18-19,21,24H,3,13-14H2,1-2H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18.6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297365 ((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1ccc2ccccc12 |r| Show InChI InChI=1S/C18H20N2O/c1-19-13-17(21)18(15-8-3-2-4-9-15)20-12-11-14-7-5-6-10-16(14)20/h2-12,17-19,21H,13H2,1H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297357 (1-Ethyl-5-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...) Show SMILES CCn1c2ccc(F)cc2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O |r| Show InChI InChI=1S/C19H22FN3O2/c1-3-22-15-10-9-14(20)11-16(15)23(19(22)25)18(17(24)12-21-2)13-7-5-4-6-8-13/h4-11,17-18,21,24H,3,12H2,1-2H3/t17-,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36.7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297356 (5-Fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-ph...) Show SMILES CCCn1c2ccc(F)cc2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O |r| Show InChI InChI=1S/C20H24FN3O2/c1-3-11-23-16-10-9-15(21)12-17(16)24(20(23)26)19(18(25)13-22-2)14-7-5-4-6-8-14/h4-10,12,18-19,22,25H,3,11,13H2,1-2H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39.4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297359 (1-Cyclobutyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(C2CCC2)c1=O |r| Show InChI InChI=1S/C21H25N3O2/c1-22-14-19(25)20(15-8-3-2-4-9-15)24-18-13-6-5-12-17(18)23(21(24)26)16-10-7-11-16/h2-6,8-9,12-13,16,19-20,22,25H,7,10-11,14H2,1H3/t19-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297360 (1-t-Butyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-p...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(c1=O)C(C)(C)C |r| Show InChI InChI=1S/C21H27N3O2/c1-21(2,3)24-17-13-9-8-12-16(17)23(20(24)26)19(18(25)14-22-4)15-10-6-5-7-11-15/h5-13,18-19,22,25H,14H2,1-4H3/t18-,19+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297358 (1-Cyclopentyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(C2CCCC2)c1=O |r| Show InChI InChI=1S/C22H27N3O2/c1-23-15-20(26)21(16-9-3-2-4-10-16)25-19-14-8-7-13-18(19)24(22(25)27)17-11-5-6-12-17/h2-4,7-10,13-14,17,20-21,23,26H,5-6,11-12,15H2,1H3/t20-,21+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	66.7	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297359 (1-Cyclobutyl-3-[(1S,2R)-2-hydroxy-3-(methylamino)-...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(C2CCC2)c1=O |r| Show InChI InChI=1S/C21H25N3O2/c1-22-14-19(25)20(15-8-3-2-4-9-15)24-18-13-6-5-12-17(18)23(21(24)26)16-10-7-11-16/h2-6,8-9,12-13,16,19-20,22,25H,7,10-11,14H2,1H3/t19-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297353 (4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3...) Show SMILES CNC[C@@H](O)[C@H](c1cccc(F)c1)n1c2c(F)cccc2n(-c2ccccc2)c1=O |r| Show InChI InChI=1S/C23H21F2N3O2/c1-26-14-20(29)21(15-7-5-8-16(24)13-15)28-22-18(25)11-6-12-19(22)27(23(28)30)17-9-3-2-4-10-17/h2-13,20-21,26,29H,14H2,1H3/t20-,21+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	91.9	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297364 (1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropy...) Show SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(C)c1=O |r| Show InChI InChI=1S/C18H21N3O2/c1-19-12-16(22)17(13-8-4-3-5-9-13)21-15-11-7-6-10-14(15)20(2)18(21)23/h3-11,16-17,19,22H,12H2,1-2H3/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	257	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50297354 (3-[(1S,2R)-3-(Ethylamino)-2-hydroxy-1-phenylpropyl...) Show SMILES CCNC[C@@H](O)[C@H](c1ccccc1)n1c2cc(F)ccc2n(C(C)C)c1=O |r| Show InChI InChI=1S/C21H26FN3O2/c1-4-23-13-19(26)20(15-8-6-5-7-9-15)25-18-12-16(22)10-11-17(18)24(14(2)3)21(25)27/h5-12,14,19-20,23,26H,4,13H2,1-3H3/t19-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
					More data for this Ligand-Target Pair