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Compile Data Set for Download or QSAR

Found 65 hits Enz. Inhib. hit(s) with all data for entry = 50040355   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393070
PNG
(CHEMBL2152731)
Show SMILES Cc1c(F)ccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C8H7FN2O2/c1-4-5(9)2-3-6-7(4)10-8(12)11(6)13/h2-3,13H,1H3,(H,10,12)
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n/an/a 70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393045
PNG
(CHEMBL2152734)
Show SMILES On1c2cc(F)cc(F)c2[nH]c1=O
Show InChI InChI=1S/C7H4F2N2O2/c8-3-1-4(9)6-5(2-3)11(13)7(12)10-6/h1-2,13H,(H,10,12)
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n/an/a 80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393060
PNG
(CHEMBL2152721)
Show SMILES On1c2cccc(F)c2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-2-1-3-5-6(4)9-7(11)10(5)12/h1-3,12H,(H,9,11)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393063
PNG
(CHEMBL2152724)
Show SMILES COc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C8H8N2O3/c1-13-6-4-2-3-5-7(6)9-8(11)10(5)12/h2-4,12H,1H3,(H,9,11)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393043
PNG
(CHEMBL2152732)
Show SMILES On1c2ccc3CCOc3c2[nH]c1=O
Show InChI InChI=1S/C9H8N2O3/c12-9-10-7-6(11(9)13)2-1-5-3-4-14-8(5)7/h1-2,13H,3-4H2,(H,10,12)
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n/an/a 200n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393061
PNG
(CHEMBL2152722)
Show SMILES Cc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C8H8N2O2/c1-5-3-2-4-6-7(5)9-8(11)10(6)12/h2-4,12H,1H3,(H,9,11)
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n/an/a 200n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393051
PNG
(CHEMBL2152740)
Show SMILES On1c2cc(F)ccc2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-1-2-5-6(3-4)10(12)7(11)9-5/h1-3,12H,(H,9,11)
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n/an/a 400n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393061
PNG
(CHEMBL2152722)
Show SMILES Cc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C8H8N2O2/c1-5-3-2-4-6-7(5)9-8(11)10(6)12/h2-4,12H,1H3,(H,9,11)
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n/an/a 400n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393063
PNG
(CHEMBL2152724)
Show SMILES COc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C8H8N2O3/c1-13-6-4-2-3-5-7(6)9-8(11)10(5)12/h2-4,12H,1H3,(H,9,11)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393045
PNG
(CHEMBL2152734)
Show SMILES On1c2cc(F)cc(F)c2[nH]c1=O
Show InChI InChI=1S/C7H4F2N2O2/c8-3-1-4(9)6-5(2-3)11(13)7(12)10-6/h1-2,13H,(H,10,12)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393060
PNG
(CHEMBL2152721)
Show SMILES On1c2cccc(F)c2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-2-1-3-5-6(4)9-7(11)10(5)12/h1-3,12H,(H,9,11)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393051
PNG
(CHEMBL2152740)
Show SMILES On1c2cc(F)ccc2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-1-2-5-6(3-4)10(12)7(11)9-5/h1-3,12H,(H,9,11)
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n/an/a 600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393059
PNG
(CHEMBL2152720)
Show SMILES On1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C7H6N2O2/c10-7-8-5-3-1-2-4-6(5)9(7)11/h1-4,11H,(H,8,10)
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n/an/a 600n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393070
PNG
(CHEMBL2152731)
Show SMILES Cc1c(F)ccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C8H7FN2O2/c1-4-5(9)2-3-6-7(4)10-8(12)11(6)13/h2-3,13H,1H3,(H,10,12)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393043
PNG
(CHEMBL2152732)
Show SMILES On1c2ccc3CCOc3c2[nH]c1=O
Show InChI InChI=1S/C9H8N2O3/c12-9-10-7-6(11(9)13)2-1-5-3-4-14-8(5)7/h1-2,13H,3-4H2,(H,10,12)
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n/an/a 800n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393046
PNG
(CHEMBL2152735)
Show SMILES On1c2ccc(F)cc2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-1-2-6-5(3-4)9-7(11)10(6)12/h1-3,12H,(H,9,11)
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n/an/a 900n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393049
PNG
(CHEMBL2152738)
Show SMILES Cc1cc2[nH]c(=O)n(O)c2cc1F
Show InChI InChI=1S/C8H7FN2O2/c1-4-2-6-7(3-5(4)9)11(13)8(12)10-6/h2-3,13H,1H3,(H,10,12)
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n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393069
PNG
(CHEMBL2152730)
Show SMILES Cc1ccc2n(O)c(=O)[nH]c2c1C
Show InChI InChI=1S/C9H10N2O2/c1-5-3-4-7-8(6(5)2)10-9(12)11(7)13/h3-4,13H,1-2H3,(H,10,12)
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n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393059
PNG
(CHEMBL2152720)
Show SMILES On1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C7H6N2O2/c10-7-8-5-3-1-2-4-6(5)9(7)11/h1-4,11H,(H,8,10)
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n/an/a 1.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393076
PNG
(CHEMBL2152718)
Show SMILES On1c2cccnc2[nH]c1=O
Show InChI InChI=1S/C6H5N3O2/c10-6-8-5-4(9(6)11)2-1-3-7-5/h1-3,11H,(H,7,8,10)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393046
PNG
(CHEMBL2152735)
Show SMILES On1c2ccc(F)cc2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-1-2-6-5(3-4)9-7(11)10(6)12/h1-3,12H,(H,9,11)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393052
PNG
(CHEMBL2152741)
Show SMILES On1c2cc(Cl)ccc2[nH]c1=O
Show InChI InChI=1S/C7H5ClN2O2/c8-4-1-2-5-6(3-4)10(12)7(11)9-5/h1-3,12H,(H,9,11)
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n/an/a 2.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393049
PNG
(CHEMBL2152738)
Show SMILES Cc1cc2[nH]c(=O)n(O)c2cc1F
Show InChI InChI=1S/C8H7FN2O2/c1-4-2-6-7(3-5(4)9)11(13)8(12)10-6/h2-3,13H,1H3,(H,10,12)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393057
PNG
(CHEMBL2152853)
Show SMILES On1c2c(F)cccc2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-2-1-3-5-6(4)10(12)7(11)9-5/h1-3,12H,(H,9,11)
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n/an/a 3.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393047
PNG
(CHEMBL2152736)
Show SMILES Cc1ccc2n(O)c(=O)[nH]c2c1
Show InChI InChI=1S/C8H8N2O2/c1-5-2-3-7-6(4-5)9-8(11)10(7)12/h2-4,12H,1H3,(H,9,11)
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n/an/a 4.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393044
PNG
(CHEMBL2152733)
Show SMILES Cc1cc(C)c2[nH]c(=O)n(O)c2c1
Show InChI InChI=1S/C9H10N2O2/c1-5-3-6(2)8-7(4-5)11(13)9(12)10-8/h3-4,13H,1-2H3,(H,10,12)
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n/an/a 4.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393047
PNG
(CHEMBL2152736)
Show SMILES Cc1ccc2n(O)c(=O)[nH]c2c1
Show InChI InChI=1S/C8H8N2O2/c1-5-2-3-7-6(4-5)9-8(11)10(7)12/h2-4,12H,1H3,(H,9,11)
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n/an/a 4.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393053
PNG
(CHEMBL2152742)
Show SMILES Cc1ccc2[nH]c(=O)n(O)c2c1
Show InChI InChI=1S/C8H8N2O2/c1-5-2-3-6-7(4-5)10(12)8(11)9-6/h2-4,12H,1H3,(H,9,11)
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n/an/a 7.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393054
PNG
(CHEMBL2152743)
Show SMILES On1c2c(F)c(F)ccc2[nH]c1=O
Show InChI InChI=1S/C7H4F2N2O2/c8-3-1-2-4-6(5(3)9)11(13)7(12)10-4/h1-2,13H,(H,10,12)
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n/an/a 8.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393052
PNG
(CHEMBL2152741)
Show SMILES On1c2cc(Cl)ccc2[nH]c1=O
Show InChI InChI=1S/C7H5ClN2O2/c8-4-1-2-5-6(3-4)10(12)7(11)9-5/h1-3,12H,(H,9,11)
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n/an/a 9.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393050
PNG
(CHEMBL2152739)
Show SMILES On1c2cc3CCCc3cc2[nH]c1=O
Show InChI InChI=1S/C10H10N2O2/c13-10-11-8-4-6-2-1-3-7(6)5-9(8)12(10)14/h4-5,14H,1-3H2,(H,11,13)
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393064
PNG
(CHEMBL2152725)
Show SMILES On1c2cccc(Cc3ccccc3)c2[nH]c1=O
Show InChI InChI=1S/C14H12N2O2/c17-14-15-13-11(7-4-8-12(13)16(14)18)9-10-5-2-1-3-6-10/h1-8,18H,9H2,(H,15,17)
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393066
PNG
(CHEMBL2152727)
Show SMILES CC(C)c1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C10H12N2O2/c1-6(2)7-4-3-5-8-9(7)11-10(13)12(8)14/h3-6,14H,1-2H3,(H,11,13)
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n/an/a 1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393054
PNG
(CHEMBL2152743)
Show SMILES On1c2c(F)c(F)ccc2[nH]c1=O
Show InChI InChI=1S/C7H4F2N2O2/c8-3-1-2-4-6(5(3)9)11(13)7(12)10-4/h1-2,13H,(H,10,12)
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n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393057
PNG
(CHEMBL2152853)
Show SMILES On1c2c(F)cccc2[nH]c1=O
Show InChI InChI=1S/C7H5FN2O2/c8-4-2-1-3-5-6(4)10(12)7(11)9-5/h1-3,12H,(H,9,11)
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n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393062
PNG
(CHEMBL2152723)
Show SMILES CCc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C9H10N2O2/c1-2-6-4-3-5-7-8(6)10-9(12)11(7)13/h3-5,13H,2H2,1H3,(H,10,12)
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n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393066
PNG
(CHEMBL2152727)
Show SMILES CC(C)c1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C10H12N2O2/c1-6(2)7-4-3-5-8-9(7)11-10(13)12(8)14/h3-6,14H,1-2H3,(H,11,13)
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n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393069
PNG
(CHEMBL2152730)
Show SMILES Cc1ccc2n(O)c(=O)[nH]c2c1C
Show InChI InChI=1S/C9H10N2O2/c1-5-3-4-7-8(6(5)2)10-9(12)11(7)13/h3-4,13H,1-2H3,(H,10,12)
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n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393044
PNG
(CHEMBL2152733)
Show SMILES Cc1cc(C)c2[nH]c(=O)n(O)c2c1
Show InChI InChI=1S/C9H10N2O2/c1-5-3-6(2)8-7(4-5)11(13)9(12)10-8/h3-4,13H,1-2H3,(H,10,12)
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n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393067
PNG
(CHEMBL2152728)
Show SMILES CCCc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C10H12N2O2/c1-2-4-7-5-3-6-8-9(7)11-10(13)12(8)14/h3,5-6,14H,2,4H2,1H3,(H,11,13)
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n/an/a 2.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393048
PNG
(CHEMBL2152737)
Show SMILES On1c2cc(F)c(F)cc2[nH]c1=O
Show InChI InChI=1S/C7H4F2N2O2/c8-3-1-5-6(2-4(3)9)11(13)7(12)10-5/h1-2,13H,(H,10,12)
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n/an/a 3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393067
PNG
(CHEMBL2152728)
Show SMILES CCCc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C10H12N2O2/c1-2-4-7-5-3-6-8-9(7)11-10(13)12(8)14/h3,5-6,14H,2,4H2,1H3,(H,11,13)
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n/an/a 3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393053
PNG
(CHEMBL2152742)
Show SMILES Cc1ccc2[nH]c(=O)n(O)c2c1
Show InChI InChI=1S/C8H8N2O2/c1-5-2-3-6-7(4-5)10(12)8(11)9-6/h2-4,12H,1H3,(H,9,11)
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n/an/a 3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393050
PNG
(CHEMBL2152739)
Show SMILES On1c2cc3CCCc3cc2[nH]c1=O
Show InChI InChI=1S/C10H10N2O2/c13-10-11-8-4-6-2-1-3-7(6)5-9(8)12(10)14/h4-5,14H,1-3H2,(H,11,13)
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n/an/a 3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393078
PNG
(CHEMBL2151056)
Show SMILES On1c2ncccc2[nH]c1=O
Show InChI InChI=1S/C6H5N3O2/c10-6-8-4-2-1-3-7-5(4)9(6)11/h1-3,11H,(H,8,10)
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n/an/a 3.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393068
PNG
(CHEMBL2152729)
Show SMILES CCC(C)c1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C11H14N2O2/c1-3-7(2)8-5-4-6-9-10(8)12-11(14)13(9)15/h4-7,15H,3H2,1-2H3,(H,12,14)
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n/an/a 4.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393058
PNG
(CHEMBL2152854)
Show SMILES Cc1cccc2[nH]c(=O)n(O)c12
Show InChI InChI=1S/C8H8N2O2/c1-5-3-2-4-6-7(5)10(12)8(11)9-6/h2-4,12H,1H3,(H,9,11)
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n/an/a 4.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393064
PNG
(CHEMBL2152725)
Show SMILES On1c2cccc(Cc3ccccc3)c2[nH]c1=O
Show InChI InChI=1S/C14H12N2O2/c17-14-15-13-11(7-4-8-12(13)16(14)18)9-10-5-2-1-3-6-10/h1-8,18H,9H2,(H,15,17)
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n/an/a 5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Sus scrofa (pig))
BDBM50393065
PNG
(CHEMBL2152726)
Show SMILES CCOc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C9H10N2O3/c1-2-14-7-5-3-4-6-8(7)10-9(12)11(6)13/h3-5,13H,2H2,1H3,(H,10,12)
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n/an/a 5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig DAAO using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50393065
PNG
(CHEMBL2152726)
Show SMILES CCOc1cccc2n(O)c(=O)[nH]c12
Show InChI InChI=1S/C9H10N2O3/c1-2-14-7-5-3-4-6-8(7)10-9(12)11(6)13/h3-5,13H,2H2,1H3,(H,10,12)
PDB
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n/an/a 5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay


ACS Med Chem Lett 3: 839-843 (2012)


Article DOI: 10.1021/ml300212a
BindingDB Entry DOI: 10.7270/Q2WM1FGX
More data for this
Ligand-Target Pair
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