BindingDB PrimarySearch

Found 14 hits Enz. Inhib. hit(s) with all data for entry = 50016554
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50170576 (1-(4-{1-[4-(2,3-Dihydroxy-propylamino)-3-methyl-ph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Binding affinity to androgen receptor by incubation with GST-hARLBD and [3H]-testosterone				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50170573 (3-(4-{1-Ethyl-1-[4-(2-hydroxy-3,3-dimethyl-butoxy)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Binding affinity to androgen receptor by incubation with GST-hARLBD and [3H]-testosterone				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50170578 (1-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Binding affinity to androgen receptor by incubation with GST-hARLBD and [3H]-testosterone				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50170582 (4-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Binding affinity to androgen receptor by incubation with GST-hARLBD and [3H]-testosterone				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50170576 (1-(4-{1-[4-(2,3-Dihydroxy-propylamino)-3-methyl-ph...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50170573 (3-(4-{1-Ethyl-1-[4-(2-hydroxy-3,3-dimethyl-butoxy)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50329704 ((R)-3-(4-(3-(4-((R)-2-hydroxy-3,3-dimethylbutoxy)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50170578 (1-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50410422 (CHEMBL199131) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50410421 (CHEMBL199122) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50410423 (CHEMBL198213) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM36720 (LG190155) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50410420 (CHEMBL198651) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Mus musculus)	BDBM50170582 (4-(4-{1-Ethyl-1-[4-(3-hydroxy-3-methyl-butylamino)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation				Bioorg Med Chem Lett 15: 4327-31 (2005) Article DOI: 10.1016/j.bmcl.2005.06.044 BindingDB Entry DOI: 10.7270/Q2SX6CS6
The University of Tokyo Curated by ChEMBL					More data for this Ligand-Target Pair