Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with all data for entry = 50041639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201069 ((1R,6S)-3-(pyridin-3-yl)-3,8-diaza-bicyclo[4.2.0]o...) Show SMILES C1N[C@H]2CN(CC[C@@H]12)c1cccnc1 |r| Show InChI InChI=1S/C11H15N3/c1-2-10(7-12-4-1)14-5-3-9-6-13-11(9)8-14/h1-2,4,7,9,11,13H,3,5-6,8H2/t9-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	70.8	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411218 (CHEMBL479613) Show SMILES C1N[C@@H]2CN(CC[C@H]12)c1cccnc1 |r| Show InChI InChI=1S/C11H15N3/c1-2-10(7-12-4-1)14-5-3-9-6-13-11(9)8-14/h1-2,4,7,9,11,13H,3,5-6,8H2/t9-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	331	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201062 ((1R,6S)-3-(6-chloro-pyridin-3-yl)-3,8-diaza-bicycl...) Show SMILES Clc1ccc(cn1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C11H14ClN3/c12-11-2-1-9(6-14-11)15-4-3-8-5-13-10(8)7-15/h1-2,6,8,10,13H,3-5,7H2/t8-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12.9	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411219 (CHEMBL479614) Show SMILES Clc1ccc(cn1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H14ClN3/c12-11-2-1-9(6-14-11)15-4-3-8-5-13-10(8)7-15/h1-2,6,8,10,13H,3-5,7H2/t8-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24.0	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201059 ((1R,6S)-3-(5-bromo-pyridin-3-yl)-3,8-diaza-bicyclo...) Show SMILES Brc1cncc(c1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C11H14BrN3/c12-9-3-10(6-13-5-9)15-2-1-8-4-14-11(8)7-15/h3,5-6,8,11,14H,1-2,4,7H2/t8-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	151	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411226 (CHEMBL506353) Show SMILES Clc1cc(cnc1Cl)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H13Cl2N3/c12-9-3-8(5-15-11(9)13)16-2-1-7-4-14-10(7)6-16/h3,5,7,10,14H,1-2,4,6H2/t7-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	81.3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411228 (CHEMBL448457) Show SMILES Brc1cc(cnc1Br)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H13Br2N3/c12-9-3-8(5-15-11(9)13)16-2-1-7-4-14-10(7)6-16/h3,5,7,10,14H,1-2,4,6H2/t7-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75.9	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411216 (CHEMBL481184) Show SMILES Brc1cncc(c1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H14BrN3/c12-9-3-10(6-13-5-9)15-2-1-8-4-14-11(8)7-15/h3,5-6,8,11,14H,1-2,4,7H2/t8-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201061 ((1R,6S)-3-(5,6-dichloro-pyridin-3-yl)-3,8-diaza-bi...) Show SMILES Clc1cc(cnc1Cl)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C11H13Cl2N3/c12-9-3-8(5-15-11(9)13)16-2-1-7-4-14-10(7)6-16/h3,5,7,10,14H,1-2,4,6H2/t7-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12.0	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201055 ((1R,6S)-3-(6-chloro-5-methyl-pyridin-3-yl)-3,8-dia...) Show SMILES Cc1cc(cnc1Cl)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C12H16ClN3/c1-8-4-10(6-15-12(8)13)16-3-2-9-5-14-11(9)7-16/h4,6,9,11,14H,2-3,5,7H2,1H3/t9-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.24	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411210 (CHEMBL481977) Show SMILES Cc1cc(cnc1Cl)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C12H16ClN3/c1-8-4-10(6-15-12(8)13)16-3-2-9-5-14-11(9)7-16/h4,6,9,11,14H,2-3,5,7H2,1H3/t9-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46.8	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411214 (CHEMBL442663) Show SMILES N#Cc1cncc(c1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C12H14N4/c13-4-9-3-11(7-14-5-9)16-2-1-10-6-15-12(10)8-16/h3,5,7,10,12,15H,1-2,6,8H2/t10-,12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201058 ((1S,6R)-5-(3,8-diaza-bicyclo[4.2.0]oct-3-yl)-nicot...) Show SMILES N#Cc1cncc(c1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C12H14N4/c13-4-9-3-11(7-14-5-9)16-2-1-10-6-15-12(10)8-16/h3,5,7,10,12,15H,1-2,6,8H2/t10-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201073 ((1R,6S)-3-(5-methoxy-pyridin-3-yl)-3,8-diaza-bicyc...) Show SMILES COc1cncc(c1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C12H17N3O/c1-16-11-4-10(6-13-7-11)15-3-2-9-5-14-12(9)8-15/h4,6-7,9,12,14H,2-3,5,8H2,1H3/t9-,12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	129	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411227 (CHEMBL480211) Show SMILES COc1cncc(c1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C12H17N3O/c1-16-11-4-10(6-13-7-11)15-3-2-9-5-14-12(9)8-15/h4,6-7,9,12,14H,2-3,5,8H2,1H3/t9-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201051 ((1R,6S)-3-(6-methoxy-pyridin-3-yl)-3,8-diaza-bicyc...) Show SMILES COc1ccc(cn1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C12H17N3O/c1-16-12-3-2-10(7-14-12)15-5-4-9-6-13-11(9)8-15/h2-3,7,9,11,13H,4-6,8H2,1H3/t9-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411217 (CHEMBL481193) Show SMILES COc1ccc(cn1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C12H17N3O/c1-16-12-3-2-10(7-14-12)15-5-4-9-6-13-11(9)8-15/h2-3,7,9,11,13H,4-6,8H2,1H3/t9-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201065 ((1R,6S)-3-(5-ethoxy-pyridin-3-yl)-3,8-diaza-bicycl...) Show SMILES CCOc1cncc(c1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C13H19N3O/c1-2-17-12-5-11(7-14-8-12)16-4-3-10-6-15-13(10)9-16/h5,7-8,10,13,15H,2-4,6,9H2,1H3/t10-,13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	617	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411221 (CHEMBL479420) Show SMILES CCOc1cncc(c1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C13H19N3O/c1-2-17-12-5-11(7-14-8-12)16-4-3-10-6-15-13(10)9-16/h5,7-8,10,13,15H,2-4,6,9H2,1H3/t10-,13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201047 ((1S,6R)-3-(5-methyl-pyridin-3-yl)-3,8-diaza-bicycl...) Show SMILES Cc1cncc(c1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C12H17N3/c1-9-4-11(7-13-5-9)15-3-2-10-6-14-12(10)8-15/h4-5,7,10,12,14H,2-3,6,8H2,1H3/t10-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	646	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201056 ((1R,6S)-3-(6-nitro-pyridin-3-yl)-3,8-diaza-bicyclo...) Show SMILES [O-][N+](=O)c1ccc(cn1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C11H14N4O2/c16-15(17)11-2-1-9(6-13-11)14-4-3-8-5-12-10(8)7-14/h1-2,6,8,10,12H,3-5,7H2/t8-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411220 (CHEMBL465916) Show SMILES [O-][N+](=O)c1ccc(cn1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H14N4O2/c16-15(17)11-2-1-9(6-13-11)14-4-3-8-5-12-10(8)7-14/h1-2,6,8,10,12H,3-5,7H2/t8-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201072 ((1R,6S)-3-(6-bromo-5-methoxy-pyridin-3-yl)-3,8-dia...) Show SMILES COc1cc(cnc1Br)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C12H16BrN3O/c1-17-11-4-9(6-15-12(11)13)16-3-2-8-5-14-10(8)7-16/h4,6,8,10,14H,2-3,5,7H2,1H3/t8-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20.9	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411225 (CHEMBL451632) Show SMILES COc1cc(cnc1Br)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C12H16BrN3O/c1-17-11-4-9(6-15-12(11)13)16-3-2-8-5-14-10(8)7-16/h4,6,8,10,14H,2-3,5,7H2,1H3/t8-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	363	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201064 ((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-3-y...) Show SMILES Brc1ncc(cc1C#N)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C12H13BrN4/c13-12-9(4-14)3-10(6-16-12)17-2-1-8-5-15-11(8)7-17/h3,6,8,11,15H,1-2,5,7H2/t8-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.17	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201067 ((1S,6R)-5-(3,8-diaza-bicyclo[4.2.0]oct-3-yl)-N-hyd...) Show SMILES ONC(=N)c1cncc(c1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C12H17N5O/c13-12(16-18)9-3-10(6-14-4-9)17-2-1-8-5-15-11(8)7-17/h3-4,6,8,11,15,18H,1-2,5,7H2,(H2,13,16)/t8-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	182	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201070 ((1R,6S)-8-pyridin-3-yl-3,8-diaza-bicyclo[4.2.0]oct...) Show SMILES C1[C@@H]2CCNC[C@@H]2N1c1cccnc1 |r| Show InChI InChI=1S/C11H15N3/c1-2-10(6-12-4-1)14-8-9-3-5-13-7-11(9)14/h1-2,4,6,9,11,13H,3,5,7-8H2/t9-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	407	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201060 ((1R,6S)-8-(6-chloro-pyridin-3-yl)-3,8-diaza-bicycl...) Show SMILES Clc1ccc(cn1)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C11H14ClN3/c12-11-2-1-9(5-14-11)15-7-8-3-4-13-6-10(8)15/h1-2,5,8,10,13H,3-4,6-7H2/t8-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	37.1	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411230 (CHEMBL451075) Show SMILES Clc1ccc(cn1)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C11H14ClN3/c12-11-2-1-9(5-14-11)15-7-8-3-4-13-6-10(8)15/h1-2,5,8,10,13H,3-4,6-7H2/t8-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	214	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201049 ((1R,6S)-8-(5,6-dichloro-pyridin-3-yl)-3,8-diaza-bi...) Show SMILES Clc1cc(cnc1Cl)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C11H13Cl2N3/c12-9-3-8(4-15-11(9)13)16-6-7-1-2-14-5-10(7)16/h3-4,7,10,14H,1-2,5-6H2/t7-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	269	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411229 (CHEMBL450667) Show SMILES Clc1cc(cnc1Cl)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C11H13Cl2N3/c12-9-3-8(4-15-11(9)13)16-6-7-1-2-14-5-10(7)16/h3-4,7,10,14H,1-2,5-6H2/t7-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	178	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201054 ((1R,6S)-8-(6-chloro-5-methyl-pyridin-3-yl)-3,8-dia...) Show SMILES Cc1cc(cnc1Cl)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C12H16ClN3/c1-8-4-10(5-15-12(8)13)16-7-9-2-3-14-6-11(9)16/h4-5,9,11,14H,2-3,6-7H2,1H3/t9-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75.9	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411213 (CHEMBL468065) Show SMILES Cc1cc(cnc1Cl)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C12H16ClN3/c1-8-4-10(5-15-12(8)13)16-7-9-2-3-14-6-11(9)16/h4-5,9,11,14H,2-3,6-7H2,1H3/t9-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	135	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201057 ((1R,6S)-8-(6-Bromo-5-methoxy-pyridin-3-yl)-3,8-dia...) Show SMILES COc1cc(cnc1Br)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C12H16BrN3O/c1-17-11-4-9(5-15-12(11)13)16-7-8-2-3-14-6-10(8)16/h4-5,8,10,14H,2-3,6-7H2,1H3/t8-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411212 (CHEMBL481002) Show SMILES COc1cc(cnc1Br)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C12H16BrN3O/c1-17-11-4-9(5-15-12(11)13)16-7-8-2-3-14-6-10(8)16/h4-5,8,10,14H,2-3,6-7H2,1H3/t8-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411211 (CHEMBL468064) Show SMILES N#Cc1cncc(c1)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C12H14N4/c13-4-9-3-11(6-15-5-9)16-8-10-1-2-14-7-12(10)16/h3,5-6,10,12,14H,1-2,7-8H2/t10-,12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201068 ((1S,6R)-5-(3,8-Diaza-bicyclo[4.2.0]oct-8-yl)-nicot...) Show SMILES N#Cc1cncc(c1)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C12H14N4/c13-4-9-3-11(6-15-5-9)16-8-10-1-2-14-7-12(10)16/h3,5-6,10,12,14H,1-2,7-8H2/t10-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201053 ((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-8-y...) Show SMILES Brc1ncc(cc1C#N)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C12H13BrN4/c13-12-9(4-14)3-10(5-16-12)17-7-8-1-2-15-6-11(8)17/h3,5,8,11,15H,1-2,6-7H2/t8-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411209 (CHEMBL448697) Show SMILES Brc1ncc(cc1C#N)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C12H13BrN4/c13-12-9(4-14)3-10(5-16-12)17-7-8-1-2-15-6-11(8)17/h3,5,8,11,15H,1-2,6-7H2/t8-,11-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	174	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201050 ((1R,6S)-2-bromo-5-(3,8-diaza-bicyclo[4.2.0]oct-8-y...) Show SMILES NC(=O)c1cc(cnc1Br)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C12H15BrN4O/c13-11-9(12(14)18)3-8(4-16-11)17-6-7-1-2-15-5-10(7)17/h3-4,7,10,15H,1-2,5-6H2,(H2,14,18)/t7-,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411223 (CHEMBL463862) Show SMILES NC(=O)c1cc(cnc1Br)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C12H15BrN4O/c13-11-9(12(14)18)3-8(4-16-11)17-6-7-1-2-15-5-10(7)17/h3-4,7,10,15H,1-2,5-6H2,(H2,14,18)/t7-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	339	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50201066 ((1R,6S)-8-(5-Methoxy-pyridin-3-yl)-3,8-diaza-bicyc...) Show SMILES COc1cncc(c1)N1C[C@@H]2CCNC[C@H]12 |r| Show InChI InChI=1S/C12H17N3O/c1-16-11-4-10(5-14-6-11)15-8-9-2-3-13-7-12(9)15/h4-6,9,12-13H,2-3,7-8H2,1H3/t9-,12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.76E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50411215 (CHEMBL443370) Show SMILES COc1cncc(c1)N1C[C@H]2CCNC[C@@H]12 |r| Show InChI InChI=1S/C12H17N3O/c1-16-11-4-10(5-14-6-11)15-8-9-2-3-13-7-12(9)15/h4-6,9,12-13H,2-3,7-8H2,1H3/t9-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha4beta2 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50201069 ((1R,6S)-3-(pyridin-3-yl)-3,8-diaza-bicyclo[4.2.0]o...) Show SMILES C1N[C@H]2CN(CC[C@@H]12)c1cccnc1 |r| Show InChI InChI=1S/C11H15N3/c1-2-10(7-12-4-1)14-5-3-9-6-13-11(9)8-14/h1-2,4,7,9,11,13H,3,5-6,8H2/t9-,11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	47.9	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha3beta4 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50411218 (CHEMBL479613) Show SMILES C1N[C@@H]2CN(CC[C@H]12)c1cccnc1 |r| Show InChI InChI=1S/C11H15N3/c1-2-10(7-12-4-1)14-5-3-9-6-13-11(9)8-14/h1-2,4,7,9,11,13H,3,5-6,8H2/t9-,11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	257	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha3beta4 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50411219 (CHEMBL479614) Show SMILES Clc1ccc(cn1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H14ClN3/c12-11-2-1-9(6-14-11)15-4-3-8-5-13-10(8)7-15/h1-2,6,8,10,13H,3-5,7H2/t8-,10-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25.1	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha3beta4 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50201059 ((1R,6S)-3-(5-bromo-pyridin-3-yl)-3,8-diaza-bicyclo...) Show SMILES Brc1cncc(c1)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C11H14BrN3/c12-9-3-10(6-13-5-9)15-2-1-8-4-14-11(8)7-15/h3,5-6,8,11,14H,1-2,4,7H2/t8-,11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75.9	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha3beta4 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50411216 (CHEMBL481184) Show SMILES Brc1cncc(c1)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H14BrN3/c12-9-3-10(6-13-5-9)15-2-1-8-4-14-11(8)7-15/h3,5-6,8,11,14H,1-2,4,7H2/t8-,11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	955	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha3beta4 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50201061 ((1R,6S)-3-(5,6-dichloro-pyridin-3-yl)-3,8-diaza-bi...) Show SMILES Clc1cc(cnc1Cl)N1CC[C@H]2CN[C@H]2C1 |r| Show InChI InChI=1S/C11H13Cl2N3/c12-9-3-8(5-15-11(9)13)16-2-1-7-4-14-10(7)6-16/h3,5,7,10,14H,1-2,4,6H2/t7-,10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha3beta4 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50411226 (CHEMBL506353) Show SMILES Clc1cc(cnc1Cl)N1CC[C@@H]2CN[C@@H]2C1 |r| Show InChI InChI=1S/C11H13Cl2N3/c12-9-3-8(5-15-11(9)13)16-2-1-7-4-14-10(7)6-16/h3,5,7,10,14H,1-2,4,6H2/t7-,10-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Burnham Institute for Medical Research Curated by ChEMBL					Assay Description Agonist activity against human alpha3beta4 nAChR				Bioorg Med Chem Lett 19: 127-31 (2008) Article DOI: 10.1016/j.bmcl.2008.11.016 BindingDB Entry DOI: 10.7270/Q2T154WM
					More data for this Ligand-Target Pair

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