Compile Data Set for Download or QSAR

Found 89 hits Enz. Inhib. hit(s) with all data for entry = 50041817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416285 (CHEMBL1171008) Show SMILES OC(=O)c1ccccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H11Cl3N2O5S/c19-10-7-15(23-29(26,27)11-5-6-13(20)14(21)8-11)17(22-9-10)28-16-4-2-1-3-12(16)18(24)25/h1-9,23H,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416284 (CHEMBL1170828) Show SMILES OC(=O)c1cccc(Oc2ncc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C18H11Cl3N2O5S/c19-11-7-16(23-29(26,27)13-4-5-14(20)15(21)8-13)17(22-9-11)28-12-3-1-2-10(6-12)18(24)25/h1-9,23H,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416308 (CHEMBL1170827) Show SMILES OC(=O)c1c(F)cccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H10Cl3FN2O5S/c19-9-6-14(24-30(27,28)10-4-5-11(20)12(21)7-10)17(23-8-9)29-15-3-1-2-13(22)16(15)18(25)26/h1-8,24H,(H,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416304 (CHEMBL1171786) Show SMILES OC(=O)c1ccccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H12Cl3NO5S/c20-11-5-8-18(28-17-4-2-1-3-13(17)19(24)25)16(9-11)23-29(26,27)12-6-7-14(21)15(22)10-12/h1-10,23H,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416283 (CHEMBL1170829) Show SMILES OC(=O)c1ccc(Oc2ncc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C18H11Cl3N2O5S/c19-11-7-16(23-29(26,27)13-5-6-14(20)15(21)8-13)17(22-9-11)28-12-3-1-10(2-4-12)18(24)25/h1-9,23H,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416289 (CHEMBL1171787) Show SMILES OC(=O)c1ccccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C17H11Cl2NO5S2/c18-10-5-6-14(25-13-4-2-1-3-11(13)17(21)22)12(9-10)20-27(23,24)16-8-7-15(19)26-16/h1-9,20H,(H,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416290 (CHEMBL1171614) Show SMILES OC(=O)c1ccccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H13Cl2NO5S/c20-12-4-3-5-14(10-12)28(25,26)22-16-11-13(21)8-9-18(16)27-17-7-2-1-6-15(17)19(23)24/h1-11,22H,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359023 (CHEMBL1170725) Show SMILES Cc1ncccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H12Cl3N3O3S/c1-10-16(3-2-6-21-10)26-17-15(7-11(18)9-22-17)23-27(24,25)12-4-5-13(19)14(20)8-12/h2-9,23H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416307 (CHEMBL1171011) Show SMILES OC(=O)c1cncc(Oc2ncc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C17H10Cl3N3O5S/c18-10-4-15(23-29(26,27)12-1-2-13(19)14(20)5-12)16(22-7-10)28-11-3-9(17(24)25)6-21-8-11/h1-8,23H,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416281 (CHEMBL1169994) Show SMILES Clc1cncc(Oc2ncc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C16H9Cl4N3O3S/c17-9-3-11(8-21-6-9)26-16-15(4-10(18)7-22-16)23-27(24,25)12-1-2-13(19)14(20)5-12/h1-8,23H	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416306 (CHEMBL1169995) Show SMILES Clc1cnc(Oc2ccc(nc2)C#N)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C17H9Cl3N4O3S/c18-10-5-16(24-28(25,26)13-3-4-14(19)15(20)6-13)17(23-8-10)27-12-2-1-11(7-21)22-9-12/h1-6,8-9,24H	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416282 (CHEMBL1170722) Show SMILES Clc1cnc(Oc2cccnc2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C16H10Cl3N3O3S/c17-10-6-15(16(21-8-10)25-11-2-1-5-20-9-11)22-26(23,24)12-3-4-13(18)14(19)7-12/h1-9,22H	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416294 (CHEMBL1171760) Show SMILES OC(=O)c1ccccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H13Cl2NO5S/c20-12-5-8-14(9-6-12)28(25,26)22-16-11-13(21)7-10-18(16)27-17-4-2-1-3-15(17)19(23)24/h1-11,22H,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416305 (CHEMBL1169660) Show SMILES OCCNC(=O)c1ccccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H16Cl3N3O5S/c21-12-9-17(26-32(29,30)13-5-6-15(22)16(23)10-13)20(25-11-12)31-18-4-2-1-3-14(18)19(28)24-7-8-27/h1-6,9-11,26-27H,7-8H2,(H,24,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416286 (CHEMBL1170801) Show SMILES OC(=O)c1ccccc1Oc1ncccc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H12Cl2N2O5S/c19-13-8-7-11(10-14(13)20)28(25,26)22-15-5-3-9-21-17(15)27-16-6-2-1-4-12(16)18(23)24/h1-10,22H,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416300 (CHEMBL1171006) Show SMILES OC(=O)c1ccccc1Oc1c(F)cc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-16-10-11(20(23,24)25)9-15(22)18(16)31-17-4-2-1-3-14(17)19(27)28/h1-10,26H,(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416298 (CHEMBL1169653) Show SMILES OC(=O)c1ccccc1Oc1ccc(F)cc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H13ClFNO5S/c20-12-5-8-14(9-6-12)28(25,26)22-16-11-13(21)7-10-18(16)27-17-4-2-1-3-15(17)19(23)24/h1-11,22H,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416311 (CHEMBL1171035) Show SMILES Cc1ncccc1Oc1ncc(cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1)C#N Show InChI InChI=1S/C18H12Cl2N4O3S/c1-11-17(3-2-6-22-11)27-18-16(7-12(9-21)10-23-18)24-28(25,26)13-4-5-14(19)15(20)8-13/h2-8,10,24H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416309 (CHEMBL1170800) Show SMILES OC(=O)c1ccccc1Oc1cnccc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H12Cl2N2O5S/c19-13-6-5-11(9-14(13)20)28(25,26)22-15-7-8-21-10-17(15)27-16-4-2-1-3-12(16)18(23)24/h1-10H,(H,21,22)(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416300 (CHEMBL1171006) Show SMILES OC(=O)c1ccccc1Oc1c(F)cc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-16-10-11(20(23,24)25)9-15(22)18(16)31-17-4-2-1-3-14(17)19(27)28/h1-10,26H,(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis in presence of 1% fetal bovine serum				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416295 (CHEMBL1169652) Show SMILES OC(=O)c1ccccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C#N Show InChI InChI=1S/C20H13ClN2O5S/c21-14-6-8-15(9-7-14)29(26,27)23-17-11-13(12-22)5-10-19(17)28-18-4-2-1-3-16(18)20(24)25/h1-11,23H,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50416303 (CHEMBL1170391) Show SMILES OC(=O)c1c(F)cccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-15-10-11(20(23,24)25)4-9-16(15)31-17-3-1-2-14(22)18(17)19(27)28/h1-10,26H,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 assessed as inhibition of MIP-1-alpha-induced [35S]-GTPgammaS binding after 3 to 4 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50416300 (CHEMBL1171006) Show SMILES OC(=O)c1ccccc1Oc1c(F)cc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-16-10-11(20(23,24)25)9-15(22)18(16)31-17-4-2-1-3-14(17)19(27)28/h1-10,26H,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 assessed as inhibition of MIP-1-alpha-induced [35S]-GTPgammaS binding after 3 to 4 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416303 (CHEMBL1170391) Show SMILES OC(=O)c1c(F)cccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-15-10-11(20(23,24)25)4-9-16(15)31-17-3-1-2-14(22)18(17)19(27)28/h1-10,26H,(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416291 (CHEMBL1169824) Show SMILES OC(=O)c1ccccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H14ClNO5S/c20-13-10-11-18(26-17-9-5-4-8-15(17)19(22)23)16(12-13)21-27(24,25)14-6-2-1-3-7-14/h1-12,21H,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416303 (CHEMBL1170391) Show SMILES OC(=O)c1c(F)cccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-15-10-11(20(23,24)25)4-9-16(15)31-17-3-1-2-14(22)18(17)19(27)28/h1-10,26H,(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis in presence of 1% fetal bovine serum				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416294 (CHEMBL1171760) Show SMILES OC(=O)c1ccccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H13Cl2NO5S/c20-12-5-8-14(9-6-12)28(25,26)22-16-11-13(21)7-10-18(16)27-17-4-2-1-3-15(17)19(23)24/h1-11,22H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416280 (CHEMBL1170187) Show SMILES Clc1cnc(Oc2cccnn2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C15H9Cl3N4O3S/c16-9-6-13(15(19-8-9)25-14-2-1-5-20-21-14)22-26(23,24)10-3-4-11(17)12(18)7-10/h1-8,22H	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416300 (CHEMBL1171006) Show SMILES OC(=O)c1ccccc1Oc1c(F)cc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-16-10-11(20(23,24)25)9-15(22)18(16)31-17-4-2-1-3-14(17)19(27)28/h1-10,26H,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416298 (CHEMBL1169653) Show SMILES OC(=O)c1ccccc1Oc1ccc(F)cc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H13ClFNO5S/c20-12-5-8-14(9-6-12)28(25,26)22-16-11-13(21)7-10-18(16)27-17-4-2-1-3-15(17)19(23)24/h1-11,22H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416301 (CHEMBL1171758) Show SMILES OC(=O)c1ccccc1Oc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H14ClNO5S/c20-13-9-11-14(12-10-13)27(24,25)21-16-6-2-4-8-18(16)26-17-7-3-1-5-15(17)19(22)23/h1-12,21H,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50416301 (CHEMBL1171758) Show SMILES OC(=O)c1ccccc1Oc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H14ClNO5S/c20-13-9-11-14(12-10-13)27(24,25)21-16-6-2-4-8-18(16)26-17-7-3-1-5-15(17)19(22)23/h1-12,21H,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 assessed as inhibition of MIP-1-alpha-induced [35S]-GTPgammaS binding after 3 to 4 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50416304 (CHEMBL1171786) Show SMILES OC(=O)c1ccccc1Oc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H12Cl3NO5S/c20-11-5-8-18(28-17-4-2-1-3-13(17)19(24)25)16(9-11)23-29(26,27)12-6-7-14(21)15(22)10-12/h1-10,23H,(H,24,25)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR4				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416301 (CHEMBL1171758) Show SMILES OC(=O)c1ccccc1Oc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H14ClNO5S/c20-13-9-11-14(12-10-13)27(24,25)21-16-6-2-4-8-18(16)26-17-7-3-1-5-15(17)19(22)23/h1-12,21H,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis in presence of 1% fetal bovine serum				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416293 (CHEMBL1171938) Show SMILES OC(=O)c1ccccc1Oc1c(Cl)cccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H13Cl2NO5S/c20-12-8-10-13(11-9-12)28(25,26)22-16-6-3-5-15(21)18(16)27-17-7-2-1-4-14(17)19(23)24/h1-11,22H,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416301 (CHEMBL1171758) Show SMILES OC(=O)c1ccccc1Oc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H14ClNO5S/c20-13-9-11-14(12-10-13)27(24,25)21-16-6-2-4-8-18(16)26-17-7-3-1-5-15(17)19(22)23/h1-12,21H,(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis in presence of 1% human serum				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416287 (CHEMBL1170799) Show SMILES OC(=O)c1ccccc1Oc1ncncc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2N3O5S/c18-12-6-5-10(7-13(12)19)28(25,26)22-14-8-20-9-21-16(14)27-15-4-2-1-3-11(15)17(23)24/h1-9,22H,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416288 (CHEMBL1171788) Show SMILES CS(=O)(=O)Nc1cc(Cl)ccc1Oc1ccccc1C(O)=O Show InChI InChI=1S/C14H12ClNO5S/c1-22(19,20)16-11-8-9(15)6-7-13(11)21-12-5-3-2-4-10(12)14(17)18/h2-8,16H,1H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50416302 (CHEMBL1171586) Show SMILES OC(=O)c1ccccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H13ClF3NO5S/c21-13-6-8-14(9-7-13)31(28,29)25-16-11-12(20(22,23)24)5-10-18(16)30-17-4-2-1-3-15(17)19(26)27/h1-11,25H,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 assessed as inhibition of MIP-1-alpha-induced [35S]-GTPgammaS binding after 3 to 4 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416293 (CHEMBL1171938) Show SMILES OC(=O)c1ccccc1Oc1c(Cl)cccc1NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H13Cl2NO5S/c20-12-8-10-13(11-9-12)28(25,26)22-16-6-3-5-15(21)18(16)27-17-7-2-1-4-14(17)19(23)24/h1-11,22H,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416292 (CHEMBL1171207) Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(Oc2ccccc2C(O)=O)c1 Show InChI InChI=1S/C20H16ClNO5S/c1-13-6-11-17(22-28(25,26)15-9-7-14(21)8-10-15)19(12-13)27-18-5-3-2-4-16(18)20(23)24/h2-12,22H,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416292 (CHEMBL1171207) Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(Oc2ccccc2C(O)=O)c1 Show InChI InChI=1S/C20H16ClNO5S/c1-13-6-11-17(22-28(25,26)15-9-7-14(21)8-10-15)19(12-13)27-18-5-3-2-4-16(18)20(23)24/h2-12,22H,1H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416310 (CHEMBL1171398) Show SMILES OC(=O)c1ccccc1Oc1nccnc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2N3O5S/c18-12-6-5-10(9-13(12)19)28(25,26)22-15-16(21-8-7-20-15)27-14-4-2-1-3-11(14)17(23)24/h1-9H,(H,20,22)(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50416285 (CHEMBL1171008) Show SMILES OC(=O)c1ccccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H11Cl3N2O5S/c19-10-7-15(23-29(26,27)11-5-6-13(20)14(21)8-11)17(22-9-10)28-16-4-2-1-3-12(16)18(24)25/h1-9,23H,(H,24,25)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR4				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416302 (CHEMBL1171586) Show SMILES OC(=O)c1ccccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H13ClF3NO5S/c21-13-6-8-14(9-7-13)31(28,29)25-16-11-12(20(22,23)24)5-10-18(16)30-17-4-2-1-3-15(17)19(26)27/h1-11,25H,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416295 (CHEMBL1169652) Show SMILES OC(=O)c1ccccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C#N Show InChI InChI=1S/C20H13ClN2O5S/c21-14-6-8-15(9-7-14)29(26,27)23-17-11-13(12-22)5-10-19(17)28-18-4-2-1-3-16(18)20(24)25/h1-11,23H,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416303 (CHEMBL1170391) Show SMILES OC(=O)c1c(F)cccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H12ClF4NO5S/c21-12-5-7-13(8-6-12)32(29,30)26-15-10-11(20(23,24)25)4-9-16(15)31-17-3-1-2-14(22)18(17)19(27)28/h1-10,26H,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50359023 (CHEMBL1170725) Show SMILES Cc1ncccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H12Cl3N3O3S/c1-10-16(3-2-6-21-10)26-17-15(7-11(18)9-22-17)23-27(24,25)12-4-5-13(19)14(20)8-12/h2-9,23H,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR4				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50416305 (CHEMBL1169660) Show SMILES OCCNC(=O)c1ccccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H16Cl3N3O5S/c21-12-9-17(26-32(29,30)13-5-6-15(22)16(23)10-13)20(25-11-12)31-18-4-2-1-3-14(18)19(28)24-7-8-27/h1-6,9-11,26-27H,7-8H2,(H,24,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at CCR4				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Mus musculus)	BDBM50416302 (CHEMBL1171586) Show SMILES OC(=O)c1ccccc1Oc1ccc(cc1NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C20H13ClF3NO5S/c21-13-6-8-14(9-7-13)31(28,29)25-16-11-12(20(22,23)24)5-10-18(16)30-17-4-2-1-3-15(17)19(26)27/h1-11,25H,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mouse CCR2				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 89 total )  |  Next  |  Last  >>

Jump to: